DE68900356D1 - Pharmazeutische zusammensetzung die ein dihydropyridinderivat enthaelt. - Google Patents
Pharmazeutische zusammensetzung die ein dihydropyridinderivat enthaelt.Info
- Publication number
- DE68900356D1 DE68900356D1 DE8989109381T DE68900356T DE68900356D1 DE 68900356 D1 DE68900356 D1 DE 68900356D1 DE 8989109381 T DE8989109381 T DE 8989109381T DE 68900356 T DE68900356 T DE 68900356T DE 68900356 D1 DE68900356 D1 DE 68900356D1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical composition
- composition containing
- dihydropyridine derivative
- dihydropyridine
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13226288 | 1988-05-30 | ||
JP1050471A JP2528706B2 (ja) | 1988-05-30 | 1989-03-02 | ジヒドロピリジン化合物の製剤組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE68900356D1 true DE68900356D1 (de) | 1991-11-28 |
Family
ID=26390939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989109381T Expired - Fee Related DE68900356D1 (de) | 1988-05-30 | 1989-05-24 | Pharmazeutische zusammensetzung die ein dihydropyridinderivat enthaelt. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4983593A (de) |
EP (1) | EP0344603B1 (de) |
JP (1) | JP2528706B2 (de) |
CA (1) | CA1332152C (de) |
DE (1) | DE68900356D1 (de) |
ES (1) | ES2051920T3 (de) |
GR (1) | GR3003615T3 (de) |
NZ (1) | NZ229309A (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW212139B (de) * | 1991-04-15 | 1993-09-01 | Yamanouchi Pharma Co Ltd | |
US5773025A (en) | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
US6726930B1 (en) * | 1993-09-09 | 2004-04-27 | Penwest Pharmaceuticals Co. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
TW487582B (en) * | 1995-08-11 | 2002-05-21 | Nissan Chemical Ind Ltd | Method for converting sparingly water-soluble medical substance to amorphous state |
KR100457273B1 (ko) * | 1996-03-18 | 2005-04-08 | 닛산 가가쿠 고교 가부시키 가이샤 | 에포니디핀염산염제제의제조방법 |
WO1998001117A1 (en) * | 1996-07-08 | 1998-01-15 | Edward Mendell Co., Inc. | Sustained release matrix for high-dose insoluble drugs |
DE69837903T2 (de) | 1997-08-11 | 2008-02-14 | Pfizer Products Inc., Groton | Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit |
EP1741424B1 (de) | 1997-08-11 | 2018-10-03 | Pfizer Products Inc. | Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit |
US6056977A (en) | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
US6350786B1 (en) † | 1998-09-22 | 2002-02-26 | Hoffmann-La Roche Inc. | Stable complexes of poorly soluble compounds in ionic polymers |
DE60039377D1 (de) | 1999-02-09 | 2008-08-21 | Pfizer Prod Inc | Zusammensetzungen basischer Arzneistoffe mit verbesserter Bioverfügbarkeit |
ES2310164T3 (es) * | 1999-02-10 | 2009-01-01 | Pfizer Products Inc. | Dispositivo de liberacion controlada por la matriz. |
EP1027886B1 (de) | 1999-02-10 | 2008-07-09 | Pfizer Products Inc. | Pharmazeutische feste Dispersionen |
ATE433318T1 (de) * | 1999-02-10 | 2009-06-15 | Pfizer Prod Inc | Osmotisches system zur verabreichung von wirkstoffen, die feste amorphe dispersionen enthalten |
US6706283B1 (en) | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
AU762291B2 (en) | 1999-09-30 | 2003-06-19 | Penwest Pharmaceutical Co. | Sustained release matrix systems for highly soluble drugs |
AU2583401A (en) * | 1999-12-20 | 2001-07-03 | Cocensys, Inc. | Process for producing nanometer particles by fluid bed spray-drying |
TR200201617T2 (tr) | 1999-12-23 | 2002-10-21 | Pfizer Products Inc. | Kuvvetlendirilmiş ilaç konsantrasyonları sağlayan farmasötik kompozisyonlar |
US7115279B2 (en) | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
WO2002038126A2 (en) * | 2000-11-08 | 2002-05-16 | Aeromatic-Fielder Ag | A process for production of particles for pharmaceutical compositions having increased bioavailability |
DE10058772A1 (de) * | 2000-11-27 | 2002-06-06 | Falk Pharma Gmbh | Verfahren zur Herstellung leicht löslicher Arzneimittelformulierungen und entsprechende Formulierungen |
ES2333645T3 (es) * | 2001-06-22 | 2010-02-25 | Bend Research, Inc. | Composiciones farmaceuticas de dispersiones de medicamentos y polimeros neutros. |
JP2004534811A (ja) * | 2001-06-22 | 2004-11-18 | ファイザー・プロダクツ・インク | ポリマーと薬剤の集合体を含む医薬組成物 |
AR038375A1 (es) * | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
WO2005117834A1 (en) * | 2004-05-27 | 2005-12-15 | Janssen Pharmaceutica N.V. | Solid dispersions of a basic drug compound and a polymer containing acidic groups |
JP2008501009A (ja) | 2004-05-28 | 2008-01-17 | ファイザー・プロダクツ・インク | 性能を高めた医薬組成物 |
EP1829549A1 (de) * | 2004-12-17 | 2007-09-05 | Ono Pharmaceutical Co., Ltd. | Amorphe zusammensetzung |
EP1923051A4 (de) * | 2005-09-06 | 2012-12-19 | Astellas Pharma Inc | Mikroteilchen einer schwerlöslichen substanz mit enterischem basismaterial, das auf der oberfläche der substanz adsorbiert ist |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
MX2010000617A (es) | 2007-07-17 | 2010-05-17 | Plexxikon Inc | Compuestos y metodos para modulacion de cinasa, e indicaciones de estos. |
US20100240711A1 (en) | 2007-09-21 | 2010-09-23 | Shionogi & Co., Ltd. | Solid preparation comprising npyy5 receptor antagonist |
EP2223702B1 (de) * | 2007-12-03 | 2019-05-08 | Tomita Pharmaceutical Co., Ltd. | Kernteilchen für eine pharmazeutische zubereitung |
WO2009140105A2 (en) | 2008-05-14 | 2009-11-19 | Merck & Co., Inc. | Formulations for cathepsin k inhibitors |
WO2010114928A2 (en) | 2009-04-03 | 2010-10-07 | F.Hoffmann-La Roche Ag | Compositions and uses thereof |
US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
US20110064806A1 (en) * | 2009-09-11 | 2011-03-17 | Transtech Pharma, Inc. | Solid compositions comprising an oxadiazoanthracene compound and methods of making and using the same |
NZ629615A (en) | 2009-11-06 | 2016-01-29 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
JP5792807B2 (ja) | 2010-06-14 | 2015-10-14 | ダウ グローバル テクノロジーズ エルエルシー | アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート |
JP5941069B2 (ja) | 2011-02-07 | 2016-06-29 | プレキシコン インコーポレーテッドPlexxikon Inc. | キナーゼ調節のための化合物および方法、ならびにそれに対する適応症 |
AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
BR112013022788A2 (pt) | 2011-03-08 | 2016-12-06 | Zalicus Pharmaceuticals Ltd | "composição farmacêutica compreendendo uma dispersão sólida de 1-(4-benzidrilpiperazin-1-il)-3,3-difenilpropan-1-ona" |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
EP2837391B1 (de) | 2013-08-12 | 2017-05-10 | Shin-Etsu Chemical Co., Ltd. | Hypromellose-Acetat-Succinat zur Verwendung als Heißschmelzextrusionsträger, Heißschmelzextrusionszusammensetzung und Verfahren zur Herstellung eines Heißschmelzextrudats |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
EP3340982B1 (de) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Verbindungen zur behandlung von immun- und entzündungserkrankungen |
CA3029262A1 (en) | 2016-06-27 | 2018-01-04 | Achillion Pharmaceuticals, Inc. | Quinazoline and indole compounds to treat medical disorders |
WO2018175648A1 (en) * | 2017-03-21 | 2018-09-27 | Bioduro, Llc | Gastrointestinal-protective formulations for oral delivery of proteins and peptides |
US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
EP3866773A4 (de) | 2018-10-16 | 2022-10-26 | Georgia State University Research Foundation, Inc. | Kohlenmonoxid-prodrugs zur behandlung von erkrankungen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5948810A (ja) | 1982-09-10 | 1984-03-21 | Sony Corp | 磁性記録体におけるデ−タのマスク及び再生方法 |
JPS62123117A (ja) | 1985-11-22 | 1987-06-04 | Nippon Chemiphar Co Ltd | 塩酸ニカルジピン経口用組成物 |
CN1016063B (zh) * | 1986-01-22 | 1992-04-01 | 日产化学工业株式会社 | 二氢吡啶-5-膦酸环亚丙基酯的制备 |
IL81419A0 (en) * | 1986-01-30 | 1987-08-31 | Syntex Inc | Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation |
-
1989
- 1989-03-02 JP JP1050471A patent/JP2528706B2/ja not_active Expired - Lifetime
- 1989-05-24 DE DE8989109381T patent/DE68900356D1/de not_active Expired - Fee Related
- 1989-05-24 EP EP89109381A patent/EP0344603B1/de not_active Expired - Lifetime
- 1989-05-24 ES ES89109381T patent/ES2051920T3/es not_active Expired - Lifetime
- 1989-05-25 CA CA000600631A patent/CA1332152C/en not_active Expired - Lifetime
- 1989-05-26 NZ NZ229309A patent/NZ229309A/en unknown
- 1989-05-30 US US07/358,144 patent/US4983593A/en not_active Expired - Lifetime
-
1992
- 1992-01-22 GR GR920400057T patent/GR3003615T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP2528706B2 (ja) | 1996-08-28 |
GR3003615T3 (de) | 1993-03-16 |
US4983593A (en) | 1991-01-08 |
EP0344603A1 (de) | 1989-12-06 |
NZ229309A (en) | 1991-06-25 |
EP0344603B1 (de) | 1991-10-23 |
JPH0249728A (ja) | 1990-02-20 |
CA1332152C (en) | 1994-09-27 |
ES2051920T3 (es) | 1994-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |