DE60326153D1 - Verfahren zur diagnose von morbus alzheimer - Google Patents
Verfahren zur diagnose von morbus alzheimerInfo
- Publication number
- DE60326153D1 DE60326153D1 DE60326153T DE60326153T DE60326153D1 DE 60326153 D1 DE60326153 D1 DE 60326153D1 DE 60326153 T DE60326153 T DE 60326153T DE 60326153 T DE60326153 T DE 60326153T DE 60326153 D1 DE60326153 D1 DE 60326153D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnosis
- subject
- methods
- present
- morbus alzheimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40001602P | 2002-07-30 | 2002-07-30 | |
PCT/US2003/023093 WO2004011943A1 (en) | 2002-07-30 | 2003-07-24 | Method of diagnosing alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60326153D1 true DE60326153D1 (de) | 2009-03-26 |
Family
ID=31188657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60326153T Expired - Lifetime DE60326153D1 (de) | 2002-07-30 | 2003-07-24 | Verfahren zur diagnose von morbus alzheimer |
Country Status (6)
Country | Link |
---|---|
US (1) | US7682795B2 (de) |
EP (1) | EP1543331B1 (de) |
AT (1) | ATE422671T1 (de) |
AU (1) | AU2003259222A1 (de) |
DE (1) | DE60326153D1 (de) |
WO (1) | WO2004011943A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
WO2005051998A2 (en) * | 2003-11-28 | 2005-06-09 | Astrazeneca Ab | Antibodies binding to a c-terminal fragment of apolipoprotein e |
US7612179B2 (en) * | 2003-11-28 | 2009-11-03 | Astrazeneca Ab | antibodies binding to a C-terminal fragment of apoliopoprotein E |
US9335331B2 (en) * | 2005-04-11 | 2016-05-10 | Cornell Research Foundation, Inc. | Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject |
KR101667623B1 (ko) | 2005-11-30 | 2016-10-19 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도 |
BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
US20090136456A1 (en) * | 2006-12-22 | 2009-05-28 | Yadong Huang | Methods of treating neurodegenerative disorders |
EP2124952A2 (de) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Verfahren zur behandlung von amyloidosen |
WO2009062152A1 (en) * | 2007-11-09 | 2009-05-14 | Washington University In St. Louis | Methods for measuring the metabolism of cns derived biomolecules in vivo |
US9102717B2 (en) * | 2010-03-01 | 2015-08-11 | The J. David Gladstone Institutes | Antibody specific for apolipoprotein and methods of use thereof |
CN102933601B (zh) | 2010-04-15 | 2016-06-08 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
US9488666B2 (en) | 2010-08-24 | 2016-11-08 | Helena Laboratories Corporation | Assay for determination of levels of lipoprotein particles in bodily fluids |
US8741298B2 (en) | 2011-02-07 | 2014-06-03 | Neotope Biosciences Limited | APOE immunotherapy |
EP3760235A1 (de) | 2014-09-30 | 2021-01-06 | Washington University | Kinetische tau-messungen |
AU2016210835B2 (en) * | 2015-01-29 | 2021-01-21 | Technophage, Investigação E Desenvolvimento Em Biotecnologia, Sa | Antibody molecules and peptide delivery systems for use in alzheimer's disease and related disorders |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811310A (en) * | 1986-09-30 | 1998-09-22 | Albert Einstein College Of Medicine Of Yeshiva Univ. | The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease |
US6287793B1 (en) * | 1988-08-19 | 2001-09-11 | Elan Pharmaceuticals, Inc. | Diagnostic methods for alzheimer's disease |
AU2414092A (en) * | 1991-08-01 | 1993-03-02 | Paul H. Voorheis | Diagnostic method for alzheimer's disease |
CA2086165A1 (en) * | 1992-04-09 | 1993-10-10 | Paul P. Tamburini | Diagnostic assay for alzheimer's disease based on the proteolysis of alzheimer's precursor protein |
WO1994009371A1 (en) * | 1992-10-09 | 1994-04-28 | Massachusetts Institute Of Technology | Antemortem diagnostic test for alzheimer's disease |
DE69333461T2 (de) * | 1992-10-13 | 2005-03-24 | Duke University | VERFAHREN ZUM nachweis der Alzheimer Krankheit |
US6300085B1 (en) * | 1993-05-03 | 2001-10-09 | The United States Of America As Represented By The Department Of Health And Human Services | Diagnostic method for Alzheimer's disease |
US5849600A (en) * | 1993-11-10 | 1998-12-15 | The Mclean Hospital Corporation | Diagnostic assays for Alzheimer's disease |
FR2716894B1 (fr) * | 1994-03-07 | 1996-05-24 | Pasteur Institut | Marqueurs génétiques utilisés conjointement pour le diagnostic de la maladie d'Alzheimer, méthode et kit de diagnostic. |
US5976798A (en) * | 1994-03-30 | 1999-11-02 | Mitokor | Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid |
US5972634A (en) * | 1994-10-19 | 1999-10-26 | The General Hospital Corporation | Diagnostic assay for Alzheimer's disease: assessment of Aβ abnormalities |
US5817789A (en) * | 1995-06-06 | 1998-10-06 | Transkaryotic Therapies, Inc. | Chimeric proteins for use in transport of a selected substance into cells |
US5976817A (en) * | 1996-10-31 | 1999-11-02 | Trustees Of Boston University | Diagnostic method for detecting Alzheimer's disease in living patients |
AU3068899A (en) * | 1998-03-05 | 1999-09-20 | Board Of Regents, The University Of Texas System | Diagnostic assay for late-onset alzheimer's disease |
CA2426030C (en) * | 2000-11-03 | 2013-12-31 | The J. David Gladstone Institutes | Methods of treating disorders related to apoe |
US6766817B2 (en) * | 2001-07-25 | 2004-07-27 | Tubarc Technologies, Llc | Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action |
-
2003
- 2003-07-24 EP EP03771762A patent/EP1543331B1/de not_active Expired - Lifetime
- 2003-07-24 US US10/627,447 patent/US7682795B2/en not_active Expired - Fee Related
- 2003-07-24 AT AT03771762T patent/ATE422671T1/de not_active IP Right Cessation
- 2003-07-24 DE DE60326153T patent/DE60326153D1/de not_active Expired - Lifetime
- 2003-07-24 AU AU2003259222A patent/AU2003259222A1/en not_active Abandoned
- 2003-07-24 WO PCT/US2003/023093 patent/WO2004011943A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1543331A1 (de) | 2005-06-22 |
EP1543331B1 (de) | 2009-02-11 |
WO2004011943A1 (en) | 2004-02-05 |
US7682795B2 (en) | 2010-03-23 |
US20040157267A1 (en) | 2004-08-12 |
AU2003259222A1 (en) | 2004-02-16 |
ATE422671T1 (de) | 2009-02-15 |
EP1543331A4 (de) | 2006-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |