DE60317305D1 - Kontaktloses verfahren zur verteilung geringer flüssigkeitsvolumen - Google Patents
Kontaktloses verfahren zur verteilung geringer flüssigkeitsvolumenInfo
- Publication number
- DE60317305D1 DE60317305D1 DE60317305T DE60317305T DE60317305D1 DE 60317305 D1 DE60317305 D1 DE 60317305D1 DE 60317305 T DE60317305 T DE 60317305T DE 60317305 T DE60317305 T DE 60317305T DE 60317305 D1 DE60317305 D1 DE 60317305D1
- Authority
- DE
- Germany
- Prior art keywords
- dispensing
- liquid
- system fluid
- communication passageway
- dispensing orifice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/148—Specific details about calibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/14—Means for pressure control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
- B01L2400/0666—Solenoid valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1041—Ink-jet like dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1044—Using pneumatic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00712—Automatic status testing, e.g. at start-up or periodic
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/2931—Diverse fluid containing pressure systems
- Y10T137/3003—Fluid separating traps or vents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/15—Inorganic acid or base [e.g., hcl, sulfuric acid, etc. ]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35185802P | 2002-01-25 | 2002-01-25 | |
US351858P | 2002-01-25 | ||
PCT/US2003/002414 WO2003065049A2 (en) | 2002-01-25 | 2003-01-27 | Low volume, non-contact liquid dispensing method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60317305D1 true DE60317305D1 (de) | 2007-12-20 |
DE60317305T2 DE60317305T2 (de) | 2008-08-28 |
Family
ID=27663031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2003617305 Expired - Lifetime DE60317305T2 (de) | 2002-01-25 | 2003-01-27 | Kontaktloses verfahren zur verteilung geringer flüssigkeitsmengen |
Country Status (7)
Country | Link |
---|---|
US (3) | US6983636B2 (de) |
EP (1) | EP1470427B1 (de) |
JP (3) | JP2005516220A (de) |
AT (1) | ATE377763T1 (de) |
CA (1) | CA2473860A1 (de) |
DE (1) | DE60317305T2 (de) |
WO (1) | WO2003065049A2 (de) |
Families Citing this family (61)
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EP1354211A1 (de) * | 2001-01-25 | 2003-10-22 | Tecan Trading AG | Pipettiervorrichtung |
US6579724B2 (en) * | 2001-09-13 | 2003-06-17 | First Ten Angstroms | Dispensing method and apparatus for dispensing very small quantities of fluid |
US6865425B2 (en) * | 2002-01-07 | 2005-03-08 | Siemens Energy & Automation, Inc. | State machine for a pulse output function |
US7410615B2 (en) * | 2002-01-24 | 2008-08-12 | Perkinelmer Las, Inc. | Precision liquid dispensing system |
US7288228B2 (en) * | 2002-02-12 | 2007-10-30 | Gilson, Inc. | Sample injection system |
CN100392587C (zh) | 2002-06-03 | 2008-06-04 | 西门子能量及自动化公司 | 用于编程智能模块的向导 |
DE10255595A1 (de) * | 2002-11-26 | 2004-06-03 | Cybio Ag | Mehrkanaldosiervorrichtung mit automatischer Kalibrierung |
US6746966B1 (en) * | 2003-01-28 | 2004-06-08 | Taiwan Semiconductor Manufacturing Company | Method to solve alignment mark blinded issues and a technology for application of semiconductor etching at a tiny area |
JP3972012B2 (ja) * | 2003-03-19 | 2007-09-05 | 株式会社日立ハイテクノロジーズ | 試料分注機構及びそれを備えた自動分析装置 |
US7543720B2 (en) * | 2003-05-05 | 2009-06-09 | The Lee Company | Method and apparatus for dispensing small volumes of fluid |
WO2005019360A1 (en) | 2003-08-25 | 2005-03-03 | Dip Tech. Ltd. | Ink for ceramic surfaces |
US8211214B2 (en) * | 2003-10-02 | 2012-07-03 | Molecular Imprints, Inc. | Single phase fluid imprint lithography method |
US7396512B2 (en) * | 2003-11-04 | 2008-07-08 | Drummond Scientific Company | Automatic precision non-contact open-loop fluid dispensing |
US20050203482A1 (en) * | 2004-03-15 | 2005-09-15 | Chinea Vanessa I. | Pharmaceutical dispensing apparatus and method |
WO2005124366A1 (en) * | 2004-06-14 | 2005-12-29 | Parker-Hannifin Corporation | Robotic handling system and method with independently operable detachable tools |
US8161020B2 (en) * | 2004-11-15 | 2012-04-17 | Zi Corporation Of Canada, Inc. | Searching for and providing objects using byte-by-byte comparison |
US8057756B2 (en) * | 2005-01-28 | 2011-11-15 | Parker-Hannifin Corporation | Sampling probe, gripper and interface for laboratory sample management systems |
US20060258011A1 (en) * | 2005-04-22 | 2006-11-16 | Igor Shvets | Cleaning of system for dispensing of liquid droplets |
US20070116608A1 (en) * | 2005-11-23 | 2007-05-24 | Birdsell Michael P | Vented ceramic tip arrangement for use with a microarray |
US20080314412A1 (en) * | 2005-12-05 | 2008-12-25 | Grippo Paul M | Self-Cleaning Injection Port for Analytical Applications |
US20090032065A1 (en) * | 2005-12-08 | 2009-02-05 | Bantz Daniel L | Syringe wash station for analytical applications |
US20090188630A1 (en) * | 2006-02-06 | 2009-07-30 | Kanji Takada | Laminated Microcapsule Sheet Producing Apparatus |
JP4906416B2 (ja) * | 2006-07-11 | 2012-03-28 | 日本碍子株式会社 | 物体の通過検出装置 |
WO2008038812A1 (fr) * | 2006-09-28 | 2008-04-03 | Shimadzu Corporation | Procédé permettant de préparer un échantillon pour la spectrométrie de masse à désorption-ionisation laser assistée par matrice et procédé de spectrométrie de masse à désorption-ionisation laser assistée par matrice |
KR101065571B1 (ko) * | 2006-09-28 | 2011-09-19 | 가부시키가이샤 시마즈세이사쿠쇼 | 파라핀 포매 표본의 탈파라핀법 및 파라핀 포매 표본의 해석법 |
US7832252B2 (en) * | 2006-10-05 | 2010-11-16 | Watson Gary W | Precise droplet injection for calibrating a gas chromatography instrument |
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US7861581B2 (en) * | 2006-12-01 | 2011-01-04 | Gamida For Life B.V. | Fluidic volume dispense verification tool |
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EP2136911A2 (de) | 2007-01-19 | 2009-12-30 | Biodot, Inc. | Systeme und verfahren für hochgeschwindigkeitsarraydruck und -hybridisierung |
US8016260B2 (en) | 2007-07-19 | 2011-09-13 | Formulatrix, Inc. | Metering assembly and method of dispensing fluid |
JP4952470B2 (ja) * | 2007-09-19 | 2012-06-13 | 和光純薬工業株式会社 | 分注装置および分注装置における吐出状態判定方法 |
CH712572B1 (de) * | 2007-11-28 | 2017-12-15 | Integra Biosciences Ag | Handpipettiergerät. |
JP2009146241A (ja) * | 2007-12-17 | 2009-07-02 | Fuji Koki Corp | 弁制御装置及び弁制御方法 |
US8808625B2 (en) * | 2008-01-11 | 2014-08-19 | National Institute Of Advanced Industrial Science And Technology | Dispensing apparatus and a dispensing method |
US8100293B2 (en) * | 2009-01-23 | 2012-01-24 | Formulatrix, Inc. | Microfluidic dispensing assembly |
JP2010223638A (ja) * | 2009-03-19 | 2010-10-07 | Beckman Coulter Inc | 分注装置、自動分析装置及び分注装置の分注監視方法 |
US8444935B2 (en) * | 2009-06-12 | 2013-05-21 | Bose Corporation | Multiple-specimen device testing with particle measurement |
KR20110046935A (ko) * | 2009-10-29 | 2011-05-06 | 포항공과대학교 산학협력단 | 액적 토출 장치 |
CN102656464A (zh) * | 2009-12-22 | 2012-09-05 | 通用电气健康护理生物科学股份公司 | 具有改进混合的分析方法 |
JP4919119B2 (ja) * | 2010-01-19 | 2012-04-18 | 株式会社日立プラントテクノロジー | 試薬分注ノズルによる分取・分注方法および試薬分取・分注機構 |
CH702769B1 (de) * | 2010-02-22 | 2019-07-31 | Reseachem Gmbh | Dosiervorrichtung und Verfahren zur Dosierung eines Fluids in ein Reaktionsgefäss. |
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US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
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FR2978064B1 (fr) * | 2011-07-18 | 2016-02-19 | Interlab | Procede et dispositif de distribution gravimetrique et en serie de solution. |
CN103998144A (zh) * | 2011-10-28 | 2014-08-20 | 惠普发展公司,有限责任合伙企业 | 并行寻址方法 |
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CN104321634B (zh) * | 2012-04-12 | 2017-12-12 | 生物辐射实验室股份有限公司 | 颗粒分配装置和方法 |
WO2013156408A1 (en) * | 2012-04-18 | 2013-10-24 | Sias Ag | Pipetting arrangement and method of controlling pipetting |
EP2986704B1 (de) | 2013-04-19 | 2019-04-03 | Siemens Healthcare Diagnostics Inc. | Kontaktloser mikrotropfenspender |
US9410977B2 (en) | 2013-08-08 | 2016-08-09 | Illumina, Inc. | Fluidic system for reagent delivery to a flow cell |
CA2955172C (en) | 2014-07-14 | 2021-07-20 | President And Fellows Of Havard College | Systems and methods for improved performance of fluidic and microfluidic systems |
PL3279618T3 (pl) * | 2016-08-01 | 2021-09-13 | Harro Höfliger Verpackungsmaschinen GmbH | Urządzenie kalibrujące i sposób dozowania jednostek dawkowania |
ES2922878T3 (es) * | 2016-10-28 | 2022-09-21 | Becton Dickinson Co | Sensor de verificación de dispensación positiva |
DE112019001892T5 (de) * | 2018-04-10 | 2021-02-04 | Elemental Scientific, Inc. | System zum Sammeln von Flüssigkeitsproben und zum Transportieren über Strecken, während ein Flüssigkeitsprobenabschnitt aufrechterhalten wird |
CN108636469A (zh) * | 2018-06-14 | 2018-10-12 | 成都瀚辰光翼科技有限责任公司 | 一种非接触式移液装置及移液方法 |
EP3823758A4 (de) | 2018-07-20 | 2022-04-06 | Brighton Technologies LLC | Verfahren und vorrichtung zur bestimmung der masse eines tröpfchens aus von einem flüssigkeitströpfchenausgabesystem gesammelten probendaten |
JP7433821B2 (ja) * | 2019-09-24 | 2024-02-20 | 東芝テック株式会社 | 薬液滴下装置 |
US11919241B1 (en) * | 2021-02-25 | 2024-03-05 | Xerox Corporation | Optimized nozzle design for drop-on-demand printers and methods thereof |
CN114965310B (zh) * | 2022-04-26 | 2023-05-26 | 上海亚新城市建设有限公司 | 水质在线监测系统量程自切换控制方法及系统 |
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-
2003
- 2003-01-27 US US10/353,804 patent/US6983636B2/en not_active Expired - Lifetime
- 2003-01-27 JP JP2003564592A patent/JP2005516220A/ja active Pending
- 2003-01-27 CA CA 2473860 patent/CA2473860A1/en not_active Abandoned
- 2003-01-27 EP EP20030704032 patent/EP1470427B1/de not_active Expired - Lifetime
- 2003-01-27 US US10/353,824 patent/US7169616B2/en active Active - Reinstated
- 2003-01-27 WO PCT/US2003/002414 patent/WO2003065049A2/en active IP Right Grant
- 2003-01-27 AT AT03704032T patent/ATE377763T1/de not_active IP Right Cessation
- 2003-01-27 DE DE2003617305 patent/DE60317305T2/de not_active Expired - Lifetime
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2007
- 2007-01-26 US US11/627,830 patent/US20070155019A1/en not_active Abandoned
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2009
- 2009-01-15 JP JP2009007035A patent/JP2009168816A/ja active Pending
- 2009-01-15 JP JP2009007032A patent/JP4621777B2/ja not_active Expired - Fee Related
Also Published As
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WO2003065049A3 (en) | 2003-10-16 |
JP4621777B2 (ja) | 2011-01-26 |
US20070155019A1 (en) | 2007-07-05 |
US20030170903A1 (en) | 2003-09-11 |
US6983636B2 (en) | 2006-01-10 |
JP2009162761A (ja) | 2009-07-23 |
EP1470427A2 (de) | 2004-10-27 |
WO2003065049A2 (en) | 2003-08-07 |
US20030167822A1 (en) | 2003-09-11 |
US7169616B2 (en) | 2007-01-30 |
CA2473860A1 (en) | 2003-08-07 |
JP2005516220A (ja) | 2005-06-02 |
DE60317305T2 (de) | 2008-08-28 |
ATE377763T1 (de) | 2007-11-15 |
JP2009168816A (ja) | 2009-07-30 |
EP1470427B1 (de) | 2007-11-07 |
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