DE60314413D1 - Verfahren und vorrichtung zur isolierung von plättchen aus blut - Google Patents

Verfahren und vorrichtung zur isolierung von plättchen aus blut

Info

Publication number
DE60314413D1
DE60314413D1 DE60314413T DE60314413T DE60314413D1 DE 60314413 D1 DE60314413 D1 DE 60314413D1 DE 60314413 T DE60314413 T DE 60314413T DE 60314413 T DE60314413 T DE 60314413T DE 60314413 D1 DE60314413 D1 DE 60314413D1
Authority
DE
Germany
Prior art keywords
float
density
platelet collection
platelets
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60314413T
Other languages
English (en)
Other versions
DE60314413T2 (de
Inventor
Randel Dorian
Richard Wood Storrs
Scott King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hanuman LLC
Original Assignee
Hanuman LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanuman LLC filed Critical Hanuman LLC
Publication of DE60314413D1 publication Critical patent/DE60314413D1/de
Application granted granted Critical
Publication of DE60314413T2 publication Critical patent/DE60314413T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0012—Settling tanks making use of filters, e.g. by floating layers of particulate material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE60314413T 2002-05-03 2003-04-24 Verfahren und vorrichtung zur isolierung von plättchen aus blut Expired - Lifetime DE60314413T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US37755902P 2002-05-03 2002-05-03
US377559P 2002-05-03
US37995102P 2002-05-10 2002-05-10
US379951P 2002-05-10
US38263902P 2002-05-21 2002-05-21
US382639P 2002-05-21
PCT/US2003/012888 WO2003092894A2 (en) 2002-05-03 2003-04-24 Method and apparatus for isolating platelets from blood

Publications (2)

Publication Number Publication Date
DE60314413D1 true DE60314413D1 (de) 2007-07-26
DE60314413T2 DE60314413T2 (de) 2008-02-21

Family

ID=29407799

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60314413T Expired - Lifetime DE60314413T2 (de) 2002-05-03 2003-04-24 Verfahren und vorrichtung zur isolierung von plättchen aus blut

Country Status (9)

Country Link
US (8) US20030205538A1 (de)
EP (1) EP1509326B1 (de)
JP (1) JP4511922B2 (de)
AT (1) ATE364446T1 (de)
AU (1) AU2003265160B2 (de)
CA (1) CA2483931C (de)
DE (1) DE60314413T2 (de)
ES (1) ES2289306T3 (de)
WO (1) WO2003092894A2 (de)

Families Citing this family (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524231B1 (en) 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
WO2002008197A1 (de) * 2000-07-24 2002-01-31 Bayer Cropscience Ag Biphenylcarboxamide
US7608258B2 (en) * 2002-04-13 2009-10-27 Allan Mishra Method for treatment of tendinosis using platelet rich plasma
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US7179391B2 (en) 2002-05-24 2007-02-20 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US7992725B2 (en) * 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7845499B2 (en) * 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7220593B2 (en) 2002-10-03 2007-05-22 Battelle Memorial Institute Buffy coat separator float system and method
US20130084594A1 (en) * 2002-10-03 2013-04-04 Battelle Memorial Institute Drug susceptibility using rare cell detection system
US20130084579A1 (en) * 2002-10-03 2013-04-04 Battelle Memorial Institute Drug susceptibility using rare cell detection system
US7297272B2 (en) 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
WO2004104553A2 (en) * 2003-05-19 2004-12-02 Harvest Technologies Corporation Method and apparatus for separating fluid components
EP1754048A1 (de) * 2003-12-08 2007-02-21 Sentronic GmbH Gesellschaft für Optische Messsysteme Sensitives system zur optischen detektion chemischer und/oder physikalischer zustandsänderungen innerhalb von verpackten medien
US7678780B2 (en) * 2003-12-29 2010-03-16 Allan Mishra Method of treating cancer using platelet releasate
US20070122906A1 (en) * 2003-12-29 2007-05-31 Allan Mishra Method of culturing cells
WO2005065269A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Compositions and method for decreasing the appearance of skin wrinkles
US7354515B2 (en) * 2004-02-23 2008-04-08 Millennium Medical Technologies, Inc. Fluid concentrator
US7462268B2 (en) 2004-08-20 2008-12-09 Allan Mishra Particle/cell separation device and compositions
CN101907622A (zh) 2004-11-24 2010-12-08 巴特尔纪念研究所 用于检测稀有细胞的方法和装置
EP1848474B1 (de) 2005-02-07 2013-06-12 Hanuman LLC Vorrichtung und verfahren mit blutplättchenreichem plasmakonzentrat
ES2426941T3 (es) 2005-02-07 2013-10-25 Hanuman Llc Aparato y procedimiento de concentrados de plasma rico en plaquetas
US7866485B2 (en) * 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US7766900B2 (en) * 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US7694828B2 (en) * 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US7829022B1 (en) 2005-06-27 2010-11-09 Lich Bryan V Centrifuge tube assembly and method of using the same
US8048297B2 (en) * 2005-08-23 2011-11-01 Biomet Biologics, Llc Method and apparatus for collecting biological materials
US7771590B2 (en) * 2005-08-23 2010-08-10 Biomet Manufacturing Corp. Method and apparatus for collecting biological materials
US8048678B2 (en) * 2005-10-27 2011-11-01 Ecw Therapeutics, Inc. Cell separation method and apparatus
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
TW200800318A (en) * 2006-06-15 2008-01-01 Antera Biotech Corp Synchronous injection mechanism for common liquid
WO2008022651A1 (en) 2006-08-21 2008-02-28 Antoine Turzi Process and device for the preparation of platelet rich plasma for extemporaneous use and combination thereof with skin and bone cells
US8034014B2 (en) 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US7806276B2 (en) 2007-04-12 2010-10-05 Hanuman, Llc Buoy suspension fractionation system
US20080269762A1 (en) * 2007-04-25 2008-10-30 Biomet Manufacturing Corp. Method and device for repair of cartilage defects
US7901344B2 (en) * 2007-05-11 2011-03-08 Biomet Biologics, Llc Methods of reducing surgical complications in cancer patients
EP3127549B1 (de) 2007-06-22 2019-12-18 Children's Medical Center Corporation Verfahren und verwendung von einem fragment von saposin a
US20090192528A1 (en) * 2008-01-29 2009-07-30 Biomet Biologics, Inc. Method and device for hernia repair
US8075468B2 (en) 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
EP2259774B1 (de) 2008-02-27 2012-12-12 Biomet Biologics, LLC Verfahren und zusammensetzungen zur abgabe eines interleukin-1-rezeptor-antagonisten
US8753690B2 (en) 2008-02-27 2014-06-17 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
WO2009111338A1 (en) 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
MX366109B (es) 2008-07-21 2019-06-26 Becton Dickinson Co Dispositivo de separacion de fases por densidad.
CN102149472B (zh) 2008-07-21 2014-08-13 贝克顿·迪金森公司 密度相分离装置
AU2009274096B2 (en) 2008-07-21 2012-08-02 Becton, Dickinson And Company Density phase separation device
US8123713B2 (en) * 2008-08-12 2012-02-28 Caridian Bct, Inc. System and method for collecting plasma protein fractions from separated blood components
US8202240B2 (en) * 2008-08-12 2012-06-19 Caridianbct, Inc. System and method for collecting plasma protein fractions from separated blood components
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
EP2337617A4 (de) 2008-10-09 2013-06-12 Bioparadox Llc Plättchenreiche plasmaformulierungen für herzbehandlungen
US8177072B2 (en) * 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US20100233282A1 (en) * 2009-03-13 2010-09-16 Allan Mishra Device and methods for delivery of bioactive materials to the right side of the heart
US8313954B2 (en) * 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
NZ596537A (en) 2009-05-15 2014-11-28 Becton Dickinson Co Density phase separation device
US20100291618A1 (en) 2009-05-15 2010-11-18 Biomerieux, Inc. Methods for rapid identification and/or characterization of a microbial agent in a sample
US9272083B2 (en) 2009-05-29 2016-03-01 Endocellutions, Inc. Apparatus and methods for aspirating and separating components of different densities from a physiological fluid containing cells
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9763875B2 (en) 2009-08-27 2017-09-19 Biomet Biologics, Llc Implantable device for production of interleukin-1 receptor antagonist
US20110052561A1 (en) * 2009-08-27 2011-03-03 Biomet Biologics,LLC Osteolysis treatment
US7927563B1 (en) * 2009-10-13 2011-04-19 Cytomedix, Inc. Kit for separation of biological fluids
KR101069877B1 (ko) 2009-10-28 2011-10-05 임기표 원심분리 키트 및 이를 이용한 원심분리 방법
EP2513137B1 (de) 2009-12-17 2018-02-28 Children's Medical Center Corporation Aus saposin-a gewonnene peptide und verwendungen davon
NL1037672C2 (nl) * 2010-02-01 2011-08-03 Eurotrol B V Werkwijze voor het bepalen van de betrouwbaarheid van een inrichting voor het meten van de concentratie van een stof in volledig bloed, werkwijze voor het behandelen van volledig bloed, houder en kit.
AU2011238581A1 (en) * 2010-03-30 2012-10-18 Battelle Memorial Institute Buffy coat separator float systems and methods
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
EP2977054A1 (de) 2010-09-03 2016-01-27 Biomet Biologics, LLC Verfahren und zusammensetzungen zur herstellung von interleukin-1-rezeptor-antagonisten
JP5676764B2 (ja) 2010-09-20 2015-02-25 レアププリス・エ・ピ・エス 多層血液製剤を製造するときに使用するための容器
US9555171B2 (en) 2010-09-30 2017-01-31 Depuy Mitek, Llc Methods and devices for collecting separate components of whole blood
KR101008583B1 (ko) 2010-10-27 2011-01-17 주식회사 메디사랑 자가 혈소판 농축물질 분리용 용기
US8394006B2 (en) 2010-11-19 2013-03-12 Kensey Nash Corporation Centrifuge
US8556794B2 (en) 2010-11-19 2013-10-15 Kensey Nash Corporation Centrifuge
US8317672B2 (en) 2010-11-19 2012-11-27 Kensey Nash Corporation Centrifuge method and apparatus
US8870733B2 (en) 2010-11-19 2014-10-28 Kensey Nash Corporation Centrifuge
US8469871B2 (en) 2010-11-19 2013-06-25 Kensey Nash Corporation Centrifuge
KR101026599B1 (ko) 2010-12-30 2011-04-04 문상호 자가 혈소판 농축물질 분리용 용기
US9011684B2 (en) 2011-03-07 2015-04-21 Spinesmith Holdings, Llc Fluid concentrator with removable cartridge
US9164079B2 (en) 2011-03-17 2015-10-20 Greyledge Technologies Llc Systems for autologous biological therapeutics
US9011846B2 (en) 2011-05-02 2015-04-21 Biomet Biologics, Llc Thrombin isolated from blood and blood fractions
US10220384B2 (en) 2011-08-09 2019-03-05 Jae Go Kwon Devices and methods for overlaying blood or cellular suspensions
WO2013023089A1 (en) 2011-08-09 2013-02-14 Eccentric Devices and methods for overlaying blood or cellular suspensions
KR101128163B1 (ko) * 2011-09-22 2012-03-23 황의재 일회용 자가 혈소판 농축물질 분리장치
AU2012340015B2 (en) 2011-11-14 2017-09-21 Alfasigma S.P.A. Assays for selecting a treatment regimen for a subject with depression and methods for treatment
EP3560509B1 (de) 2011-12-22 2024-01-31 Children's Medical Center Corporation Aus saposin-a gewonnene peptide und verwendungen davon
US8632736B2 (en) * 2012-01-06 2014-01-21 Rarecyte, Inc. Float and tube system for separating a suspension with an internal trap
EP2803396B1 (de) 2012-01-12 2018-02-28 Panasonic Healthcare Holdings Co., Ltd. Probenkonzentrierungsbehälter und entsprechendes probenkonzentrierungsverfahren
US9327296B2 (en) 2012-01-27 2016-05-03 Fenwal, Inc. Fluid separation chambers for fluid processing systems
KR101162750B1 (ko) * 2012-03-19 2012-07-05 (주)세원메디텍 혈액 원심분리용 용기
US9120095B2 (en) * 2012-03-29 2015-09-01 Biomet Biologics, Llc Apparatus and method for separating and concentrating a component of a fluid
US8984932B2 (en) 2012-07-18 2015-03-24 Theranos, Inc. Rapid measurement of formed blood component sedimentation rate from small sample volumes
AU2013292378A1 (en) 2012-07-18 2015-01-29 Theranos Ip Company, Llc Rapid measurement of formed blood component sedimentation rate from small sample volumes
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
WO2014039082A1 (en) * 2012-09-04 2014-03-13 Becton, Dickinson And Company Bacterial pre-concentration and detection technique
DK2892496T3 (en) 2012-09-06 2017-09-25 Theranos Inc BODY LIQUID SAMPLING DEVICES
US11318459B2 (en) * 2012-09-07 2022-05-03 Becton, Dickinson And Company Method and apparatus for microorganism detection
WO2014120797A1 (en) 2013-01-29 2014-08-07 Endocellutions, Inc. Cell concentration devices and methods
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9878011B2 (en) 2013-03-15 2018-01-30 Biomet Biologics, Llc Treatment of inflammatory respiratory disease using biological solutions
US9758806B2 (en) 2013-03-15 2017-09-12 Biomet Biologics, Llc Acellular compositions for treating inflammatory disorders
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
CN104704106B (zh) 2013-04-11 2016-08-24 早安生物株式会社 提取自血小板的血液分离容器
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
WO2015025912A1 (ja) * 2013-08-22 2015-02-26 株式会社ジェイ・エム・エス 血液成分分離用装置
US9696242B2 (en) * 2013-10-10 2017-07-04 Biomet Biologics, Llc Fixed chamber separator with adjustment withdrawal member
EP3074507B1 (de) 2013-11-26 2022-01-05 Biomet Biologics, LLC Verfahren zur vermittlung von makrophagenphänotypen
US20170023546A1 (en) * 2013-12-05 2017-01-26 Theranos, Inc. Systems, devices, and methods for bodily fluid sample collection, transport, and handling
EP3660140A1 (de) 2014-01-31 2020-06-03 DSM IP Assets B.V. Zentrifuge zur behandlung von fettgewebe und verfahren zur verwendung
EP3116464B1 (de) 2014-03-12 2022-06-08 Labrador Diagnostics LLC Vorrichtungen zur entnahme von körperflüssigkeitsproben
US9937445B2 (en) 2014-03-27 2018-04-10 Biomet Biologics, Llc System and method for separating a fraction
KR101585857B1 (ko) * 2014-05-23 2016-01-15 주식회사 라온 Prp 추출키트
US20150367064A1 (en) * 2014-06-18 2015-12-24 Patrick Pennie Platelet Concentrating System
US11278884B2 (en) 2014-10-28 2022-03-22 Arteriocyte Medical Systems, Inc. Centrifuge tube comprising a floating buoy, and methods for using the same
US10441635B2 (en) 2014-11-10 2019-10-15 Biomet Biologics, Llc Methods of treating pain using protein solutions
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
JP2016158557A (ja) * 2015-03-02 2016-09-05 セイコーエプソン株式会社 容器、生体関連物質精製カートリッジ及び生体関連物質精製カートリッジ組立体キット
US9763800B2 (en) 2015-03-18 2017-09-19 Biomet C. V. Implant configured for hammertoe and small bone fixation
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
WO2017004606A1 (en) 2015-07-02 2017-01-05 Arthrex, Inc. Methods and devices for preparation of enriched biological fluids
US10371606B2 (en) 2015-07-21 2019-08-06 Theraos IP Company, LLC Bodily fluid sample collection and transport
US10207044B2 (en) 2015-07-29 2019-02-19 Fenwal, Inc. Five-port blood separation chamber and methods of using the same
CN105289772B (zh) * 2015-09-22 2016-12-28 烟台森森环保科技有限公司 一种富血小板血浆专用离心管
EP3165921A1 (de) * 2015-11-05 2017-05-10 Dominik Olbrzymek Kit zur zentrifugalen trennung biologischer flüssigkeitskomponenten und verfahren zur zentrifugalen trennung biologischer flüssigkeitskomponenten
CA3044657C (en) 2015-11-24 2022-10-18 Royal Biologics Methods and apparatus for separating fluid components
AU2017204355B2 (en) 2016-07-08 2021-09-09 Mako Surgical Corp. Scaffold for alloprosthetic composite implant
US20200230526A1 (en) * 2017-07-24 2020-07-23 Arteriocyte Medical Systems, Inc. Methods of preparing liquid exchanged biological fractions, and devices for use in practicing the same
US11305273B2 (en) 2017-07-27 2022-04-19 Biomerieux, Inc. Isolation tube with a rheological control member and a plunger
EP3470142A1 (de) 2017-10-11 2019-04-17 Orthogen AG Vorrichtung mit einer ersten kammer zur aufnahme eines körperfluids
JP2021531059A (ja) 2018-07-09 2021-11-18 ハヌマン ペリカン，インコーポレイテッド 血液を処理するための装置および方法
EP3784363A4 (de) 2018-07-09 2022-02-16 Hanuman Pelican, Inc. Vorrichtung und verfahren zur trennung von blutkomponenten
CN113329809B (zh) * 2018-12-08 2023-01-31 魏民 用于生产细胞疗法产品的装置
US20220088589A1 (en) 2019-01-21 2022-03-24 Eclipse Medcorp, Llc Methods, Systems and Apparatus for Separating Components of a Biological Sample
EP3890799A4 (de) 2019-02-06 2022-10-26 Hanuman Pelican, Inc. Vorrichtung und verfahren zur konzentration von plättchenreichem plasma
CN109794082A (zh) * 2019-03-20 2019-05-24 林侯汎 一种用于抽取血液内单个核细胞的装置
EP3799896A1 (de) 2019-10-04 2021-04-07 Arthrex, Inc Vorrichtungen und verfahren zur herstellung therapeutischer flüssigkeiten
KR102323493B1 (ko) * 2019-11-11 2021-11-09 이준석 체액 성분 분리 장치
WO2024039424A1 (en) * 2022-08-15 2024-02-22 Hanuman Pelican, Inc. Float securement apparatus and methods

Family Cites Families (511)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US593333A (en) * 1897-11-09 Device for separating liquids of different
US280820A (en) * 1883-07-10 Milk-can
US1468313A (en) 1920-07-03 1923-09-18 Firm Luftfahrzeugbau Schutte L Process of producing a cold glue from blood
GB229644A (en) 1924-02-19 1925-10-08 Robert Vogel A method of producing a substance adapted to tampon wounds
US2553004A (en) 1949-03-11 1951-05-15 Rabatine Michael Dividing protractor
US2722257A (en) 1953-02-12 1955-11-01 Compule Corp Sampling tube equipment
SE169293C1 (de) 1958-03-13 1959-11-10
US3013557A (en) 1959-04-13 1961-12-19 Hazleton Lab Inc Combination syringe, shipping container and centrifuge tube
US3159159A (en) 1960-06-01 1964-12-01 Milton J Cohen Fluid withdrawal device and container
US3141846A (en) 1962-04-05 1964-07-21 Western States Machine Co Load control unit for cyclical centrifugal installation
DK113248B (da) 1963-09-02 1969-03-03 Pharmacia Ab Fremgangsmåde til fremstilling af med en eller flere mono- eller dihydroxyalkylgrupper substitueret dekstran.
US3300051A (en) 1963-09-26 1967-01-24 Internat Equipment Co Filter tube for use in a centrifuge
JPS497539B1 (de) 1966-04-13 1974-02-21
US3469369A (en) 1966-12-29 1969-09-30 Bell Telephone Labor Inc Method for preparing and applying a viscous fluid
US3441143A (en) 1967-02-10 1969-04-29 Marvel Eng Co Plural element filter assembly
US3545671A (en) 1967-02-14 1970-12-08 Eugene Ross Lab Inc Apparatus for and method of collecting,storing,separating and dispensing blood and blood components
US3409165A (en) * 1967-04-03 1968-11-05 Olin Mathieson Floating deck
US3508653A (en) 1967-11-17 1970-04-28 Charles M Coleman Method and apparatus for fluid handling and separation
US3596652A (en) 1968-10-14 1971-08-03 Bio Science Labor Fluid separatory device
US3583627A (en) 1969-09-04 1971-06-08 Onslow H Wilson Apparatus for the concentration of macromolecules and subcellular particles from dilute solutions
US3654925A (en) 1969-09-23 1972-04-11 Becton Dickinson Co Plasma separator system
US3647070A (en) 1970-06-11 1972-03-07 Technicon Corp Method and apparatus for the provision of fluid interface barriers
US3741400A (en) 1970-06-15 1973-06-26 J Dick Blood sample container
US3661265A (en) * 1970-07-27 1972-05-09 Contemporary Research And Dev Serum separator type container
USRE32089E (en) * 1970-08-25 1986-03-04 Amicon Corporation Blood fractionating process and apparatus for carrying out same
US3723244A (en) * 1971-01-18 1973-03-27 Atomic Energy Commission Fibrous fibrin sheet and method for producing same
US3706305A (en) 1971-03-03 1972-12-19 Harold J Berger Combination blood sampling vacuum syringe centrifuge container and specimen cup
US3706306A (en) 1971-03-03 1972-12-19 Harold J Berger Combination blood sampling vacuum syringe centrifuge container and specimen cup
DE2115032C3 (de) 1971-03-29 1975-05-07 Kernforschungsanlage Juelich Gmbh, 5170 Juelich Vorrichtung zum Trennen zweier Phasen bei der Flüssig-Flüssig-Extraktion in einer Zentrifuge
US3814248A (en) 1971-09-07 1974-06-04 Corning Glass Works Method and apparatus for fluid collection and/or partitioning
US3965889A (en) 1971-11-26 1976-06-29 Commissariat A L'energie Atomique Apparatus for the sampling of blood and the separation of plasma under anaerobic conditions
US3779383A (en) 1972-04-25 1973-12-18 Becton Dickinson Co Sealed assembly for separation of blood components and method
US3849072A (en) 1972-04-25 1974-11-19 Becton Dickinson Co Plasma separator
US3785549A (en) 1972-07-31 1974-01-15 Haemonetics Corp Centrifuge chuck for disposable, snap-in centrifuge rotor
DE7239445U (de) 1972-10-27 1973-08-02 Merten Utz P Einwegspritze, insbesondere zur Entnahme von Blutproben
US4537767A (en) 1973-01-29 1985-08-27 Pharmacia Aktiebolag Method for cleansing fluid discharging skin surfaces, wounds and mucous membranes and means for carrying out the method
SE452109B (sv) 1973-01-29 1987-11-16 Pharmacia Ab Rengoringsmedel for vetskande utvertes sarytor
US3850369A (en) * 1973-03-08 1974-11-26 Coulter Electronics Centrifuge for preparing platelet rich plasma
US3879295A (en) * 1973-08-17 1975-04-22 Eastman Kodak Co Vacutainer with positive separation barrier
US4001122A (en) 1973-08-22 1977-01-04 Telan Corporation Method and device for separating blood components
US3896733A (en) 1973-10-18 1975-07-29 Pall Corp Autotransfusion apparatus
US3962085A (en) 1973-12-19 1976-06-08 Abbott Laboratories Skimmer assembly
US3897337A (en) 1974-02-27 1975-07-29 Becton Dickinson Co Plasma separator assembly having interface-seeking piston with centrifugal valve
US3941699A (en) 1974-02-27 1976-03-02 Becton, Dickinson And Company Plasma separator with centrifugal valve
US3957654A (en) 1974-02-27 1976-05-18 Becton, Dickinson And Company Plasma separator with barrier to eject sealant
US3931010A (en) 1974-02-27 1976-01-06 Becton, Dickinson And Company Serum/plasma separators with centrifugal valves
US3935113A (en) 1974-02-27 1976-01-27 Becton, Dickinson And Company Serum/plasma separator with centrifugal valve
US3909419A (en) * 1974-02-27 1975-09-30 Becton Dickinson Co Plasma separator with squeezed sealant
US3951801A (en) 1974-02-27 1976-04-20 Becton, Dickinson And Company Serum/plasma separator-strut stop type
US3945928A (en) 1974-02-27 1976-03-23 Becton, Dickinson And Company Serum/plasma separators with centrifugal valves
US3897343A (en) * 1974-02-27 1975-07-29 Becton Dickinson Co Plasma separator-hydrostatic pressure type
US3894952A (en) 1974-02-27 1975-07-15 Becton Dickinson Co Serum/plasma separator assembly having interface-seeking piston
US3887466A (en) 1974-02-27 1975-06-03 Becton Dickinson Co Serum/plasma separator cannula fluid by-pass type centrifugal valve cannula seal
US3929646A (en) 1974-07-22 1975-12-30 Technicon Instr Serum separator and fibrin filter
US3931018A (en) * 1974-08-09 1976-01-06 Becton, Dickinson And Company Assembly for collection, separation and filtration of blood
US4059108A (en) 1974-08-15 1977-11-22 Haemonetics Corporation Process for pheresis procedure and disposable pheresis bowl therefor
US4204537A (en) 1974-08-15 1980-05-27 Haemonetics Corporation Process for pheresis procedure and disposable plasma
DE2444524A1 (de) 1974-09-18 1976-04-08 Oeser Henning Dr Verfahren und vorrichtung zur ausfaellung von human-blutplasma-bestandteilen
US3982691A (en) * 1974-10-09 1976-09-28 Schlutz Charles A Centrifuge separation and washing device and method
US3972812A (en) 1975-05-08 1976-08-03 Becton, Dickinson And Company Blood serum separation filter disc
US4020831A (en) 1975-12-04 1977-05-03 Technicon Instruments Corporation Blood collecting syringe
US4088582A (en) * 1976-01-16 1978-05-09 Sherwood Medical Industries Inc. Blood phase separation means
US4055501A (en) * 1976-01-16 1977-10-25 Sherwood Medical Industries Inc. Fluid collection device with phase partitioning means
US4027660A (en) * 1976-04-02 1977-06-07 Wardlaw Stephen C Material layer volume determination
CA1074273A (en) 1976-05-06 1980-03-25 Sherwood Medical Industries Inc. Phase separation device
US4046699A (en) * 1976-11-01 1977-09-06 Corning Glass Works Access device for centrifugal separation assemblies
FR2377041A1 (fr) 1977-01-10 1978-08-04 Levine Robert Procede pour obtenir une meilleure separation des couches cellulaires dans un echantillon sanguin centrifuge
AT381466B (de) 1977-03-16 1986-10-27 Ballies Uwe Trennroehrchen fuer zentrifugaltrennung
US4189385A (en) 1977-05-03 1980-02-19 Greenspan Donald J Method and apparatus for separating serum or plasma from the formed elements of the blood
US5217426A (en) 1977-08-12 1993-06-08 Baxter International Inc. Combination disposable plastic blood receiving container and blood component centrifuge
US4146172A (en) 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
US4187979A (en) * 1978-09-21 1980-02-12 Baxter Travenol Laboratories, Inc. Method and system for fractionating a quantity of blood into the components thereof
US4303193A (en) 1979-01-22 1981-12-01 Haemonetics Corporation Apparatus for separating blood into components thereof
US4229298A (en) 1979-02-05 1980-10-21 The Western States Machine Company Method and apparatus for determining the thickness of a charge wall formed in a centrifugal basket
US4453927A (en) 1979-02-07 1984-06-12 Gesco International Method and apparatus for microfiltration of blood
AT359653B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
AT359652B (de) 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
US4314823A (en) 1979-03-05 1982-02-09 Dionex Corporation Combination apparatus and method for chromatographic separation and quantitative analysis of multiple ionic species
JPS5917386B2 (ja) 1979-03-23 1984-04-20 テルモ株式会社 血液分離方法および装置
US4300717A (en) 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
NO146616C (no) 1979-10-04 1982-11-03 Ken Heimreid Fremgangsmaate og anordning ved preparering til undersoekelse av ukoagulert blod.
US4269718A (en) * 1980-05-05 1981-05-26 The Institutes Of Medical Sciences Process and device for centrifugal separation of platelets
ES501923A0 (es) 1980-05-08 1982-11-16 Terumo Corp Aparato para separacion de la sangre
JPS6053845B2 (ja) 1980-06-19 1985-11-27 キヤノン株式会社 レンズ鏡胴ユニットの製造方法
US4332351A (en) 1980-09-22 1982-06-01 International Business Machines Corporation Blood fraction extracting centrifuge
DE3101733C2 (de) 1981-01-21 1982-10-14 Uwe Dr.Med. 2300 Kiel Ballies Trennelement in einem Trennröhrchen zur Zentrifugaltrennung
DE3101752A1 (de) 1981-01-21 1982-08-26 Behringwerke Ag, 3550 Marburg "verfahren zur reinigung der blutgerinnungsfaktoren ii, vii, ix und/oder x und danach hergestellte praeparationen"
US4424132A (en) 1981-02-05 1984-01-03 Asahi Kasei Kogyo Kabushiki Kaisha Apparatus and method for separating blood components
DE3105624A1 (de) 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
US4417981A (en) 1981-05-04 1983-11-29 Becton, Dickinson And Company Blood phase separator device
US4322298A (en) * 1981-06-01 1982-03-30 Advanced Blood Component Technology, Inc. Centrifugal cell separator, and method of use thereof
ATE13810T1 (de) 1981-06-25 1985-07-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundabdeckung.
US4442655A (en) 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
ATE20824T1 (de) 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg Angereichertes plasmaderivat zur unterstuetzung von wundverschluss und wundheilung.
US4735726A (en) 1981-07-22 1988-04-05 E. I. Du Pont De Nemours And Company Plasmapheresis by reciprocatory pulsatile filtration
GB2104401B (en) 1981-08-25 1985-03-20 Krauss Maffei Ag Support plate for centrifuges
US4464167A (en) * 1981-09-03 1984-08-07 Haemonetics Corporation Pheresis apparatus
US4416654A (en) * 1981-09-03 1983-11-22 Haemonetics Corporation Pheresis apparatus
DE3203775A1 (de) 1982-02-04 1983-08-11 Behringwerke Ag, 3550 Marburg Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung
DE3212412C2 (de) 1982-04-02 1986-01-02 Dr. Ruhland Nachf. GmbH, 8425 Neustadt Gewebeverklebbare kollagene Wundauflage
US4511662A (en) 1982-06-18 1985-04-16 Bio-Rad Laboratories, Inc. Simultaneous assay for T and B lymphocyte populations and subpopulations
US4443345A (en) * 1982-06-28 1984-04-17 Wells John R Serum preparator
JPS5928766A (ja) 1982-08-10 1984-02-15 Sony Corp 遅延回路
US4445550B1 (en) 1982-08-20 1999-03-09 Scholle Corp Flexible walled container having membrane fitment for use with aseptic filling apparatus
US4680025A (en) 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
WO1984000905A1 (en) 1982-08-24 1984-03-15 Baxter Travenol Lab Blood component collection systems and methods
US4722790A (en) 1982-09-13 1988-02-02 Cawley Leo P On-line plasma modification means
US4839058A (en) 1982-09-13 1989-06-13 Cawley Leo P On-line plasma modification method
EP0109374A1 (de) 1982-10-08 1984-05-23 Antoon Soetens Vorrichtung zum Auffangen von Sonnenenergie auf einem Dach oder ähnlichem
SE8206767D0 (sv) * 1982-11-26 1982-11-26 Seroteknik Hb Sett och anordning for satsvis centrifugalseparering av blod
US5034135A (en) 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US4632761A (en) 1983-08-15 1986-12-30 W. R. Grace & Co. Centrifugal microconcentrator and methods for its use
US4755301A (en) 1983-08-15 1988-07-05 W. R. Grace & Co. Apparatus and method for centrifugal recovery of retentate
US4672969A (en) 1983-10-06 1987-06-16 Sonomo Corporation Laser healing method
JPS60250014A (ja) 1984-05-28 1985-12-10 Mitsui Toatsu Chem Inc 濃縮用樹脂
CH665565A5 (de) 1983-10-22 1988-05-31 Mitsui Toatsu Chemicals Verfahren zur steuerung der konzentration einer eine makromolekulare verbindung enthaltenden waessrigen loesung oder emulsion.
CA1244774A (en) 1983-11-09 1988-11-15 Thomas Jefferson University Medium for storing blood platelets
DE3410286C2 (de) * 1984-03-21 1986-01-23 Fresenius AG, 6380 Bad Homburg Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens
AT379311B (de) 1984-03-29 1985-12-27 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
US4577514A (en) 1984-04-09 1986-03-25 Vanderbilt University Method and apparatus for sampling liquid phase components from a liquid-semisolid fluid
JPS6144825A (ja) 1984-08-09 1986-03-04 Unitika Ltd 止血剤
US4610656A (en) 1984-08-21 1986-09-09 Mehealus Partnership Fully portable semi-automatic mechanical heart-lung substitution system and method
US4776964A (en) * 1984-08-24 1988-10-11 William F. McLaughlin Closed hemapheresis system and method
US4627879A (en) 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
US4928603A (en) 1984-09-07 1990-05-29 The Trustees Of Columbia University In The City Of New York Method of preparing a cryoprecipitated suspension and use thereof
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US5053134A (en) 1984-12-04 1991-10-01 Becton Dickinson And Company Lymphocyte collection tube
US4917801A (en) 1984-12-04 1990-04-17 Becton Dickinson And Company Lymphocyte collection tube
US4639316A (en) 1984-12-14 1987-01-27 Becton, Dickinson And Company Automatic liquid component separator
US5372945A (en) 1985-06-06 1994-12-13 Alchas; Paul G. Device and method for collecting and processing fat tissue and procuring microvessel endothelial cells to produce endothelial cell product
AT382783B (de) 1985-06-20 1987-04-10 Immuno Ag Vorrichtung zur applikation eines gewebeklebstoffes
SE448323B (sv) * 1985-08-27 1987-02-09 Ersson Nils Olof Forfarande och anordnig att separera serum eller plasma fran blod
WO1987001307A1 (en) 1985-09-10 1987-03-12 Vereniging Het Nederlands Kanker Instituut Method and device for the separation and isolation of blood or bone marrow components
US4724317A (en) 1985-12-05 1988-02-09 Baxter Travenol Laboratories, Inc. Optical data collection apparatus and method used with moving members
US4871462A (en) 1985-12-23 1989-10-03 Haemonetics Corporation Enhanced separation of blood components
US4755300A (en) 1985-12-23 1988-07-05 Haemonetics Corporation Couette membrane filtration apparatus for separating suspended components in a fluid medium using high shear
AU578554B2 (en) * 1986-01-24 1988-10-27 Japanese Red Cross Society Centrifugal method of separating blood components
US5112490A (en) 1986-02-19 1992-05-12 Jon Turpen Sample filtration, separation and dispensing device
ES2004281A6 (es) * 1986-04-04 1988-12-16 Univ Jefferson Una superficie protesica implantable para implantacion en un paciente humano
SE8601891D0 (sv) * 1986-04-24 1986-04-24 Svante Jonsson Maskin for plasmabytesbehandling och trombocytgivning
DE3615558A1 (de) 1986-05-09 1987-11-12 Behringwerke Ag Verfahren zur herstellung eines faktor v-konzentrats
DE3622642A1 (de) 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
US4983158A (en) * 1986-07-22 1991-01-08 Haemonetics Corporation Plasmapheresis centrifuge bowl
US4943273A (en) 1986-07-22 1990-07-24 Haemonetics Corporation Disposable centrifuge bowl for blood processing
US4714457A (en) 1986-09-15 1987-12-22 Robert Alterbaum Method and apparatus for use in preparation of fibrinogen from a patient's blood
DK475386D0 (da) 1986-10-03 1986-10-03 Weis Fogh Ulla Sivertsen Fremgangsmaade og apparat til fremstilling af biologiske stoffer
US4915847A (en) 1987-08-04 1990-04-10 Baxter International Inc. Cryoglobulin separation
US4929242A (en) * 1986-11-26 1990-05-29 Baxter International Inc. Solution and method for maintaining patency of a catheter
CH673117A5 (de) 1986-12-10 1990-02-15 Ajinomoto Kk
US4933291A (en) 1986-12-22 1990-06-12 Eastman Kodak Company Centrifugable pipette tip and pipette therefor
US5053127A (en) * 1987-01-13 1991-10-01 William F. McLaughlin Continuous centrifugation system and method for directly deriving intermediate density material from a suspension
US5641414A (en) 1987-01-30 1997-06-24 Baxter International Inc. Blood processing systems and methods which restrict in flow of whole blood to increase platelet yields
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US5370802A (en) * 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US4834890A (en) 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US4832851A (en) 1987-02-02 1989-05-23 W. R. Grace & Co. Centrifugal force-enhanced filtration of fluids
US4983157A (en) * 1987-03-23 1991-01-08 Ceramics Process Systems Corp. Centrifugation system using static layer
US5030341A (en) 1987-04-03 1991-07-09 Andronic Technologies, Inc. Apparatus for separating phases of blood
US5019243A (en) * 1987-04-03 1991-05-28 Mcewen James A Apparatus for collecting blood
IT1203461B (it) 1987-04-08 1989-02-15 Dideco Spa Cella per la centrifugazione del sangue
US4939081A (en) 1987-05-27 1990-07-03 The Netherlands Cancer Institute Cell-separation
US4846835A (en) 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US4738655A (en) 1987-06-17 1988-04-19 Utah Bioresearch, Inc. Apparatus and method for obtaining a rapid hematocrit
DE3723092C1 (de) 1987-07-13 1989-01-26 Westfalia Separator Ag Durchlaufzentrifuge zur industriellen Produktion von Proteinen aus menschlichem Blutplasma
US5260420A (en) 1987-07-30 1993-11-09 Centre Regional De Transfusion Sanguine De Lille Concentrate of thrombin coagulable proteins, the method of obtaining same and therapeutical use thereof
DE3726227A1 (de) 1987-08-07 1989-02-16 Krauss Maffei Ag Vorrichtung zum ergebnisabhaengigen steuern einer filterzentrifuge
US4877520A (en) 1987-10-08 1989-10-31 Becton, Dickinson And Company Device for separating the components of a liquid sample having higher and lower specific gravities
US4818386A (en) * 1987-10-08 1989-04-04 Becton, Dickinson And Company Device for separating the components of a liquid sample having higher and lower specific gravities
US4844818A (en) 1987-10-23 1989-07-04 Becton Dickinson & Company Method for separating the cellular components of blood samples
US4957638A (en) 1987-10-23 1990-09-18 Becton Dickinson And Company Method for separating the cellular components of blood samples
US5290552A (en) * 1988-05-02 1994-03-01 Matrix Pharmaceutical, Inc./Project Hear Surgical adhesive material
US4957637A (en) 1988-05-23 1990-09-18 Sherwood Medical Company Serum separator system for centrifuge with piercable membrane
AT397203B (de) * 1988-05-31 1994-02-25 Immuno Ag Gewebeklebstoff
AU617265B2 (en) * 1988-06-23 1991-11-21 Asahi Medical Co. Ltd. Method for separating blood into blood components, and blood components separator unit
US5024613A (en) 1988-07-18 1991-06-18 Pfizer Hospital Products Group, Inc. Blood recovery system and method
US4874368A (en) 1988-07-25 1989-10-17 Micromedics, Inc. Fibrin glue delivery system
US4846780A (en) 1988-08-10 1989-07-11 Exxon Production Research Company Centrifuge processor and liquid level control system
US4902281A (en) 1988-08-16 1990-02-20 Corus Medical Corporation Fibrinogen dispensing kit
US4946601A (en) 1988-08-22 1990-08-07 Sherwood Medical Company Blood serum separator tube
JPH0271747U (de) 1988-11-22 1990-05-31
US4973168A (en) 1989-01-13 1990-11-27 Chan Kwan Ho Vacuum mixing/bone cement cartridge and kit
DE8900469U1 (de) * 1989-01-17 1990-05-23 Espe Stiftung & Co Produktions- Und Vertriebs Kg, 8031 Seefeld, De
US5002571A (en) * 1989-02-06 1991-03-26 Donnell Jr Francis E O Intraocular lens implant and method of locating and adhering within the posterior chamber
SE8900586L (sv) 1989-02-21 1990-08-22 Pharmacia Ab Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader
JPH02129224U (de) 1989-03-29 1990-10-24
CA2011100C (en) * 1989-05-24 1996-06-11 Stephen C. Wardlaw Centrifuged material layer measurements taken in an evacuated tube
US5226877A (en) 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
US5000970A (en) * 1989-06-30 1991-03-19 Horizons International Foods, Inc. Process for preparing reheatable french fried potatoes
WO1991001383A1 (en) 1989-07-14 1991-02-07 Michigan State University Method for diagnosing blood clotting disorders
US5207638A (en) 1989-08-24 1993-05-04 Hemotrans, Inc. Blood transfer apparatus
US5258126A (en) 1989-09-12 1993-11-02 Pall Corporation Method for obtaining platelets
US5152905A (en) 1989-09-12 1992-10-06 Pall Corporation Method for processing blood for human transfusion
US5100564A (en) * 1990-11-06 1992-03-31 Pall Corporation Blood collection and processing system
US5316674A (en) 1989-09-12 1994-05-31 Pall Corporation Device for processing blood for human transfusion
IL95641A0 (en) 1989-09-15 1991-06-30 Curative Tech Inc Preparation of a platelet releasate product
US5104375A (en) * 1989-10-16 1992-04-14 Johnson & Johnson Medical, Inc. Locking holder for a pair of syringes and method of use
US5039401A (en) 1990-05-16 1991-08-13 Eastman Kodak Company Blood collection and centrifugal separation device including a valve
US5030215A (en) 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
US5219328A (en) 1990-01-03 1993-06-15 Cryolife, Inc. Fibrin sealant delivery method
US5318524A (en) 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
NL9000090A (nl) 1990-01-15 1991-08-01 Harimex Ligos Bv Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat.
US5185001A (en) * 1990-01-18 1993-02-09 The Research Foundation Of State University Of New York Method of preparing autologous plasma fibrin and application apparatus therefor
US5047004A (en) 1990-02-07 1991-09-10 Wells John R Automatic decanting centrifuge
US5178602A (en) * 1990-02-07 1993-01-12 Wells John R Automatic decanting centrifuge
US5045048A (en) 1990-03-29 1991-09-03 Haemonetics Corporation Rotary centrifuge bowl and seal for blood processing
US5204537A (en) * 1990-03-30 1993-04-20 Recognition Equipment Incorporated Thickness sensor comprising a leaf spring means, and a light sensor
DK119490D0 (da) 1990-05-14 1990-05-14 Unes As Apparat til fremstilling af et koncentrat af koagulationsfaktorer, saasom fibrinogen, fra en blodportion
US5171456A (en) * 1990-06-14 1992-12-15 Baxter International Inc. Automated blood component separation procedure and apparatus promoting different functional characteristics in multiple blood components
US5156586A (en) 1990-07-10 1992-10-20 Bardyne Orbital separator for orbitally separating a mixture
FR2665378B1 (fr) 1990-08-03 1992-10-09 Guigan Jean Dispositif pour separer par centrifugation deux phases d'un echantillon d'un liquide heterogene, utilisable notamment pour la separation du plasma du sang total.
US5420250A (en) 1990-08-06 1995-05-30 Fibrin Corporation Phase transfer process for producing native plasma protein concentrates
US5641622A (en) 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5173295A (en) * 1990-10-05 1992-12-22 Advance Biofactures Of Curacao, N.V. Method of enhancing the regeneration of injured nerves and adhesive pharamaceutical formulation therefor
US5112484A (en) 1990-10-11 1992-05-12 Zuk, Inc. Filtration apparatus
US5217627A (en) 1990-11-06 1993-06-08 Pall Corporation System and method for processing biological fluid
US5197985A (en) * 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5226914A (en) 1990-11-16 1993-07-13 Caplan Arnold I Method for treating connective tissue disorders
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5955436A (en) 1990-11-20 1999-09-21 Alcon Laboratories, Inc. Use of platelet derived growth factor to enhance wound healing
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US5234608A (en) * 1990-12-11 1993-08-10 Baxter International Inc. Systems and methods for processing cellular rich suspensions
JPH0774772B2 (ja) * 1990-12-31 1995-08-09 エイ． レビン ロバート 血液サンプリング組立体、ターゲット細胞の採取方法およびターゲット成分の採取方法
US5137832A (en) 1991-01-02 1992-08-11 Becton Dickinson & Company Quantification of fibrinogen in whole blood samples contained in a tube using a float to separate materials
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5156613A (en) 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
US5762798A (en) * 1991-04-12 1998-06-09 Minntech Corporation Hollow fiber membranes and method of manufacture
US5236604A (en) * 1991-05-29 1993-08-17 Sherwood Medical Company Serum separation blood collection tube and the method of using thereof
US5269927A (en) * 1991-05-29 1993-12-14 Sherwood Medical Company Separation device for use in blood collection tubes
US5203825A (en) * 1991-06-07 1993-04-20 Becton, Dickinson And Company Capillary tube assembly including a vented cap
SE9101853D0 (sv) 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
DE4126341C1 (de) * 1991-08-09 1993-01-28 Fresenius Ag, 6380 Bad Homburg, De
US5251786A (en) * 1991-08-16 1993-10-12 Helena Laboratories Corporation Biological fluid collection and delivery apparatus and method
BR9103724A (pt) 1991-08-29 1993-03-30 Univ Estadual Paulista Julio D Cola de fibrina derivada de veneno de cobra e processo para sua preparacao
DE69229272T2 (de) 1991-09-05 2000-02-03 Baxter Int Topischer fibrinogenkomplex
DE4129516C2 (de) * 1991-09-06 2000-03-09 Fresenius Ag Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile
EP0534178B1 (de) 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Verbesserter Gewebekleber, zubereitet aus Kryopräzipitat
JP3388352B2 (ja) 1991-10-18 2003-03-17 バクスター、インターナショナル、インコーポレイテッド 骨髄キット
US5344752A (en) * 1991-10-30 1994-09-06 Thomas Jefferson University Plasma-based platelet concentrate preparations
CA2074671A1 (en) 1991-11-04 1993-05-05 Thomas Bormann Device and method for separating plasma from a biological fluid
US5190057A (en) * 1991-12-13 1993-03-02 Faezeh Sarfarazi Sarfarazi method of closing a corneal incision
US5833866A (en) 1991-12-23 1998-11-10 Baxter International Inc. Blood collection systems and methods which derive instantaneous blood component yield information during blood processing
US5804079A (en) 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
DE4202667C1 (de) 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
DE4204012A1 (de) * 1992-02-12 1993-08-19 Ulrich Prof Dr Zimmermann Mitogenfreie substanz, deren herstellung und verwendung
EP0639980A1 (de) * 1992-02-26 1995-03-01 Allergan, Inc. Verwendung von wachstumsfaktor, abstammend von blutplättchen, zur ophthalmischen wundheilung
US5298016A (en) 1992-03-02 1994-03-29 Advanced Haemotechnologies Apparatus for separating plasma and other wastes from blood
SE9201413L (sv) 1992-04-30 1993-10-31 Stiftelsen Foer Medicinsk Tekn Beredning och sätt för aferesframställning av trombocytkoncentrat med väsentligt förlängd hållbarhet
US5271852A (en) * 1992-05-01 1993-12-21 E. I. Du Pont De Nemours And Company Centrifugal methods using a phase-separation tube
US5403272A (en) * 1992-05-29 1995-04-04 Baxter International Inc. Apparatus and methods for generating leukocyte free platelet concentrate
US5275585A (en) 1992-06-03 1994-01-04 Zimmer Patient Care Autotransfusion system with portable detachable vacuum source
FR2691911B1 (fr) * 1992-06-05 1994-11-25 Delmas Olivier Dispositif permettant l'obtention d'un surnageant de thrombocytes activés, procédé mettant en Óoeuvre le dispositif et surnageant obtenu.
DK83092D0 (da) 1992-06-24 1992-06-24 Unes As Fremgangsmaade til udvinding af thrombin
US5443481A (en) 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites
WO1994006460A1 (en) 1992-09-21 1994-03-31 Vitaphore Corporation Embolization plugs for blood vessels
FR2696095B1 (fr) 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
US5354483A (en) 1992-10-01 1994-10-11 Andronic Technologies, Inc. Double-ended tube for separating phases of blood
CN1091315A (zh) 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
DE69328738T2 (de) * 1992-12-01 2000-12-07 Haemonetics Corp Vorrichtung zur apherese von roten blutkörperchen
US5520885A (en) 1993-01-19 1996-05-28 Thermogenesis Corporation Fibrinogen processing apparatus, method and container
US5370221A (en) 1993-01-29 1994-12-06 Biomet, Inc. Flexible package for bone cement components
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
US5290918A (en) * 1993-02-23 1994-03-01 Haemacure Biotech Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
US5330974A (en) 1993-03-01 1994-07-19 Fibratek, Inc. Therapeutic fibrinogen compositions
US5614106A (en) * 1993-03-12 1997-03-25 Baxter International Inc. Method and apparatus for collection of platelets
GB9307321D0 (en) 1993-04-07 1993-06-02 Knight Scient Ltd Method of separating particles from a filter
WO1994025086A1 (en) * 1993-04-27 1994-11-10 Haemonetics Corporation Apheresis apparatus and method
US5409833A (en) 1993-07-01 1995-04-25 Baxter International Inc. Microvessel cell isolation apparatus
US5456885A (en) * 1993-07-12 1995-10-10 Coleman; Charles M. Fluid collection, separation and dispensing tube
US6189704B1 (en) 1993-07-12 2001-02-20 Baxter International Inc. Inline filter
JPH07103969A (ja) 1993-08-13 1995-04-21 Niigata Kako Kk 血液分離部材及び血液分離用採血管
US5916557A (en) 1993-11-12 1999-06-29 The Trustees Of Columbia University In The City Of New York Methods of repairing connective tissues
CA2131738C (en) 1993-11-17 2001-09-04 Lonny R. Kelley Flow enhanced one-pass centrifuge separator
ZA948564B (en) * 1993-11-19 1995-07-26 Bristol Myers Squibb Co Liquid separation apparatus and method
US5411885A (en) 1993-12-17 1995-05-02 New York Blood Center, Inc. Methods for tissue embedding and tissue culturing
US5437598A (en) * 1994-01-21 1995-08-01 Cobe Laboratories, Inc. Automation of plasma sequestration
WO1995023165A1 (fr) * 1994-02-23 1995-08-31 Kyowa Hakko Kogyo Co., Ltd. Accelerateur de croissance des thrombocytes
US5545339A (en) * 1994-02-25 1996-08-13 Pall Corporation Method for processing biological fluid and treating separated component
EP0754064B1 (de) * 1994-04-08 2003-05-28 Atrix Laboratories, Inc. Beigeordnetes polymersystem zur verwendung mit einer medizinischen vorrichtung
US5533518A (en) * 1994-04-22 1996-07-09 Becton, Dickinson And Company Blood collection assembly including mechanical phase separating insert
US5723331A (en) * 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
US5795751A (en) 1994-06-09 1998-08-18 Lockheed Martin Idaho Technologies Company Biofilter for removal of nitrogen oxides from contaminated gases under aerobic conditions
US5501371A (en) * 1994-07-07 1996-03-26 Schwartz-Feldman; Jean Mixing syringe
US5646004A (en) 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
US5648223A (en) 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
US5474687A (en) 1994-08-31 1995-12-12 Activated Cell Therapy, Inc. Methods for enriching CD34+ human hematopoietic progenitor cells
US5840502A (en) 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5663051A (en) 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
US5577513A (en) * 1994-08-31 1996-11-26 Activated Cell Therapy, Inc. Centrifugation syringe, system and method
US5575778A (en) * 1994-09-21 1996-11-19 B. Braun Melsungen Ag Blood-taking device
US5588958A (en) 1994-09-21 1996-12-31 C. R. Bard, Inc. Closed wound orthopaedic drainage and autotransfusion system
US5645540A (en) 1994-10-11 1997-07-08 Stryker Corporation Blood conservation system
US5733253A (en) 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US5601711A (en) 1994-10-31 1997-02-11 Gelman Sciences Inc. Selective separation filter device
CZ164697A3 (cs) 1994-12-02 1998-03-18 Bristol-Myers Sguibb Company Způsob oddělování složky z plazmy a zařízení k provádění tohoto způsobu
MX9704017A (es) 1994-12-02 1998-02-28 Bristol Myers Squibb Co Metodo y dispositivo para separar fibrina i del plasma sanguineo.
US5733446A (en) 1994-12-02 1998-03-31 Bristol-Myers Squibb Company Centrifuge with annular filter
CA2182862C (en) 1994-12-07 2006-10-03 Richard D. Antanavich Plasma concentrate and tissue sealant compositions
US5585007A (en) 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5560830A (en) 1994-12-13 1996-10-01 Coleman; Charles M. Separator float and tubular body for blood collection and separation and method of use thereof
NO301562B1 (no) 1994-12-21 1997-11-10 Exxon Production Research Co Anordning for måling
US5510102A (en) * 1995-01-23 1996-04-23 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
US7011644B1 (en) * 1995-02-06 2006-03-14 Andrew Mark S Tissue liquefaction and aspiration for dental treatment
US6676629B2 (en) * 1995-02-06 2004-01-13 Mark S. Andrew Tissue liquefaction and aspiration for dental treatment
US5823986A (en) 1995-02-08 1998-10-20 Medtronic, Inc. Perfusion system
FR2731176B1 (fr) 1995-03-02 1997-04-30 Sidel Sa Installation de fabrication de recipients par soufflage de preformes en matiere plastique
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5716616A (en) * 1995-03-28 1998-02-10 Thomas Jefferson University Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects
US5643192A (en) 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
US6053856A (en) * 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
US5674173A (en) * 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
AU702151B2 (en) 1995-04-18 1999-02-18 Gambro Inc Particle separation apparatus and method
US6022306A (en) * 1995-04-18 2000-02-08 Cobe Laboratories, Inc. Method and apparatus for collecting hyperconcentrated platelets
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
USRE38730E1 (en) 1995-05-05 2005-04-26 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and method of treating physiological fluids
EP0836487A1 (de) * 1995-06-06 1998-04-22 Quantic Biomedical Partners Vorrichtung und verfahren zum konzentrieren von plasma
US5958250A (en) 1995-06-07 1999-09-28 Baxter International Inc. Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent
US5738644A (en) * 1995-06-07 1998-04-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5837150A (en) 1995-06-07 1998-11-17 Cobe Laboratories, Inc. Extracorporeal blood processing methods
US20020192632A1 (en) 1995-06-07 2002-12-19 Hei Derek J. Method and devices for the removal of psoralens from blood products
US5750025A (en) 1995-06-07 1998-05-12 Cobe Laboratories, Inc. Disposable for an apheresis system with a contoured support
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
US5632905A (en) * 1995-08-07 1997-05-27 Haynes; John L. Method and apparatus for separating formed and unformed components
US6351659B1 (en) * 1995-09-28 2002-02-26 Brainlab Med. Computersysteme Gmbh Neuro-navigation system
JPH10512960A (ja) 1995-10-03 1998-12-08 ベックマン インスツルメンツ インコーポレーテッド 軸線回り回転の血液分離装置及び方法
US5736033A (en) * 1995-12-13 1998-04-07 Coleman; Charles M. Separator float for blood collection tubes with water swellable material
US5643193A (en) 1995-12-13 1997-07-01 Haemonetics Corporation Apparatus for collection washing and reinfusion of shed blood
US5817519A (en) 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6025201A (en) * 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6200606B1 (en) * 1996-01-16 2001-03-13 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration
US5733466A (en) * 1996-02-06 1998-03-31 International Business Machines Corporation Electrolytic method of depositing gold connectors on a printed circuit board
US5865785A (en) 1996-02-23 1999-02-02 Baxter International Inc. Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes
US5834418A (en) 1996-03-20 1998-11-10 Theratechnologies, Inc. Process for the preparation of platelet growth factors extract
US5707876A (en) * 1996-03-25 1998-01-13 Stephen C. Wardlaw Method and apparatus for harvesting constituent layers from a centrifuged material mixture
DE69605062T2 (de) 1996-04-24 2000-07-13 Claude Fell Zelltrennungsvorrichtung für biologische flüssigkeiten wie blut
JP2000509307A (ja) 1996-04-30 2000-07-25 メドトロニック，インコーポレイテッド 自己由来フィブリン密封材の製造方法
WO2000062828A1 (en) 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
US6099493A (en) 1997-05-06 2000-08-08 Sherwood Services, Ag Continuous autotransfusion filtration system
JP2859845B2 (ja) 1996-05-09 1999-02-24 照明 伊藤 血清分取補助装置
US6020196A (en) 1996-05-09 2000-02-01 Baxter International Inc. Devices for harvesting and homogenizing adipose tissue containing autologous endothelial cells
US5811151A (en) 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
US5824084A (en) 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
AU730749B2 (en) 1996-07-25 2001-03-15 Genzyme Corporation Chondrocyte media formulations and culture procedures
WO1998012274A1 (en) 1996-09-23 1998-03-26 Chandrashekar Pathak Methods and devices for preparing protein concentrates
FR2757770B1 (fr) 1996-12-30 1999-02-26 Inoteb Procede de preparation d'une colle biologique capable de coaguler par simple addition d'ions calcium
US5879624A (en) 1997-01-15 1999-03-09 Boehringer Laboratories, Inc. Method and apparatus for collecting and processing blood
US5961210A (en) 1997-01-24 1999-10-05 Mccardel; Brian R. Bone cement preparation device, and methods of constructing and utilizing same
US5889584A (en) * 1997-03-10 1999-03-30 Robert A. Levine Assembly for rapid measurement of cell layers
WO1998043720A1 (en) 1997-04-03 1998-10-08 Baxter International Inc. Interface detection and control systems and methods
WO1998048938A1 (en) 1997-04-25 1998-11-05 Washington State University Research Foundation Semi-continuous, small volume centrifugal blood separator
US5860937A (en) * 1997-04-30 1999-01-19 Becton, Dickinson & Company Evacuated sample collection tube with aqueous additive
DE19718648A1 (de) 1997-05-02 1998-11-05 Merck Patent Gmbh Verfahren und Vorrichtung zur Herstellung von steril verpacktem Knochenzement
US6063624A (en) 1997-06-09 2000-05-16 Baxter International Inc. Platelet suspensions and methods for resuspending platelets
WO1998057678A2 (en) * 1997-06-18 1998-12-23 Cohesion Technologies, Inc. Compositions containing thrombin and microfibrillar collagen
IT1292410B1 (it) 1997-06-24 1999-02-08 Roberto Beretta Contenitore di pronto impiego per ottenere colla di fibrina autologa
US6979307B2 (en) 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US6007811A (en) 1997-07-01 1999-12-28 Sea Run Holdings, Inc. Method of producing fibrin sealant from clotting factors in fish blood
US5918622A (en) * 1997-07-01 1999-07-06 Bermad Separation valve
US6200287B1 (en) * 1997-09-05 2001-03-13 Gambro, Inc. Extracorporeal blood processing methods and apparatus
US5955032A (en) 1997-09-12 1999-09-21 Becton Dickinson And Company Collection container assembly
US5938621A (en) 1997-09-12 1999-08-17 Becton Dickinson And Company Collection container assembly
US5934803A (en) 1997-10-30 1999-08-10 Physical Systems, Inc. Apparatus and method for mixing multi-part reaction materials under vacuum
CA2307743A1 (en) * 1997-10-30 1999-05-14 The General Hospital Corporation Bonding of cartilaginous matrices using isolated chondrocytes
US7031775B2 (en) 1997-11-07 2006-04-18 Medtronic, Inc. Method and system for myocardial infarction repair
US5951160A (en) 1997-11-20 1999-09-14 Biomet, Inc. Method and apparatus for packaging, mixing and delivering bone cement
US6478808B2 (en) 1997-12-17 2002-11-12 Closys Corporation Clotting cascade initiating apparatus and methods of use and methods of closing wounds
US6051146A (en) * 1998-01-20 2000-04-18 Cobe Laboratories, Inc. Methods for separation of particles
JP4441115B2 (ja) 1998-03-13 2010-03-31 オシリス セラピューティクス，インコーポレイテッド ヒト非自己間葉幹細胞を使用する方法と利用
WO1999047190A1 (en) 1998-03-16 1999-09-23 Medtronic, Inc. Hemostatic system and components for extracorporeal circuit
US5924972A (en) * 1998-03-24 1999-07-20 Turvaville; L. Jackson Portable D.C. powered centrifuge
US6835377B2 (en) 1998-05-13 2004-12-28 Osiris Therapeutics, Inc. Osteoarthritis cartilage regeneration
CN1307491A (zh) * 1998-06-01 2001-08-08 丰收技术股份有限公司 血液抽取系统
US6327491B1 (en) 1998-07-06 2001-12-04 Neutar, Llc Customized surgical fixture
US6274090B1 (en) 1998-08-05 2001-08-14 Thermogenesis Corp. Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby
US6308747B1 (en) * 1998-10-01 2001-10-30 Barry Farris Needleless method and apparatus for transferring liquid from a container to an injecting device without ambient air contamination
US6563953B2 (en) 1998-11-30 2003-05-13 Microsoft Corporation Predictive image compression using a single variable length code for both the luminance and chrominance blocks for each macroblock
US6328765B1 (en) 1998-12-03 2001-12-11 Gore Enterprise Holdings, Inc. Methods and articles for regenerating living tissue
US6479298B1 (en) 1998-12-05 2002-11-12 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6280400B1 (en) * 1998-12-05 2001-08-28 Becton Dickinson And Company Device and method for separating component of a liquid sample
US6516953B1 (en) * 1998-12-05 2003-02-11 Becton, Dickinson And Company Device for separating components of a fluid sample
US6406671B1 (en) 1998-12-05 2002-06-18 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6153113A (en) 1999-02-22 2000-11-28 Cobe Laboratories, Inc. Method for using ligands in particle separation
US6294187B1 (en) 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
US6322785B1 (en) * 1999-03-02 2001-11-27 Natrex Technologies Methods and compositions for bone graft implants
US6777231B1 (en) 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US20030082152A1 (en) 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
US20050076396A1 (en) 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
KR100968165B1 (ko) 1999-03-10 2010-07-06 더 리전츠 오브 더 유니버시티 오브 캘리포니아 지방 유래 간세포 및 격자
US20050153442A1 (en) 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6296602B1 (en) * 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
CN1238083C (zh) 1999-04-12 2006-01-25 丰收技术股份有限公司 制造富含血小板的血浆和/或血小板浓缩液的方法和设备
US6417004B1 (en) 1999-04-29 2002-07-09 Helena Laboratories Corporation Enhancing clot detection in activated clotting time and other fibrin endpoint based tests
EP1057534A1 (de) 1999-06-03 2000-12-06 Haemonetics Corporation Zentrifugentrommel mit Filterkern
US6629919B2 (en) 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
US6472162B1 (en) 1999-06-04 2002-10-29 Thermogenesis Corp. Method for preparing thrombin for use in a biological glue
US6316247B1 (en) 1999-06-15 2001-11-13 University Of Pittsburgh System and method for refining liposuctioned adipose tissue
WO2001003756A1 (en) * 1999-07-08 2001-01-18 Implant Innovations, Inc. Platelet concentration syringe kit
US6716187B1 (en) 1999-07-08 2004-04-06 Implant Innovations, Inc. Platelet concentration syringe kit
US6758978B1 (en) * 1999-08-06 2004-07-06 Gl&V Management Hungary Kft. Deep bed thickener/clarifiers with enhanced liquid removal
US6487992B1 (en) 1999-11-22 2002-12-03 Robert L. Hollis Dog behavior monitoring and training apparatus
US6803022B2 (en) * 1999-12-06 2004-10-12 Becton, Dickinson And Company Device and method for separating components of a fluid sample
US6471069B2 (en) 1999-12-03 2002-10-29 Becton Dickinson And Company Device for separating components of a fluid sample
US6409528B1 (en) 1999-12-06 2002-06-25 Becton, Dickinson And Company Device and method for collecting, preparation and stabilizing a sample
ITAL990010U1 (it) 1999-12-14 2001-06-14 Maria Cristina Sacchi Nuova metodica di laboratorio per preparare gel e membrane piastriniche ottenute dal concentrato piastrinico.
KR100505445B1 (ko) 1999-12-28 2005-08-04 주식회사 하이닉스반도체 반도체 소자의 강유전체 캐패시터 및 그 형성방법
US6651075B1 (en) * 2000-02-16 2003-11-18 Microsoft Corporation Support for multiple temporal snapshots of same volume
US6286670B1 (en) 2000-03-14 2001-09-11 Biomet, Inc. Method and apparatus for mixing a compound utilizing a gas permeable barrier
US20020104808A1 (en) 2000-06-30 2002-08-08 Lou Blasetti Method and apparatus for producing platelet rich plasma and/or platelet concentrate
US6708227B1 (en) * 2000-04-24 2004-03-16 Microsoft Corporation Method and system for providing common coordination and administration of multiple snapshot providers
ATE382408T1 (de) 2000-04-28 2008-01-15 Harvest Technologies Corp Plattentrenneinrichtung für blutbestandteile
AU6888201A (en) * 2000-06-29 2002-01-08 Biosyntech Canada Inc Composition and method for the repair and regeneration of cartilage and other tissues
US6368498B1 (en) 2000-08-30 2002-04-09 Paul Guilmette Liquid separator
US7411006B2 (en) 2000-10-23 2008-08-12 Shanbrom Technologies, Llc Enhanced production of blood clotting factors and fibrin fabric
RU2003117016A (ru) 2000-11-08 2004-12-10 Октафарма АГ (CH) Способ получения латентного антитромбина iii
US20020090711A1 (en) 2000-11-20 2002-07-11 Goran Karlsson Process for preparing latent antithrombin III
WO2002060925A1 (en) 2001-01-30 2002-08-08 Genzymes Corporation Method of producing latent antithrombin iii
US6911202B2 (en) 2001-02-06 2005-06-28 Abraham Amir Cosmetic repair using cartilage producing cells and medical implants coated therewith
US20030050709A1 (en) * 2001-02-23 2003-03-13 Ulrich Noth Trabecular bone-derived human mesenchymal stem cells
AU2002232104A1 (en) 2001-02-26 2002-09-12 Ben-Ami Ballin Syringe for use in blood analysis
US6723131B2 (en) 2001-02-28 2004-04-20 The Cleveland Clinic Foundation Composite bone marrow graft material with method and kit
JP2005098704A (ja) 2001-03-13 2005-04-14 Hajime Ogata 比重の異なる微粒子の分別法
EP1381410A2 (de) 2001-04-09 2004-01-21 Medtronic, Inc. Zentrifugationsverfahren zur isolierung der blutbestandteile, und deren verwendungen
DE60234926D1 (de) 2001-06-06 2010-02-11 Perfusion Partners & Associate Zentrifugenröhrenanordnung
US6623959B2 (en) 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US6764531B2 (en) 2001-07-06 2004-07-20 J. S. Hogan Method and apparatus for cleaning a gas
JP4197157B2 (ja) * 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 軟骨修復再生装置および方法
WO2003015800A1 (en) 2001-08-09 2003-02-27 Ivoclar Vivadent, Inc. Tissue implants and methods for making and using same
US7371409B2 (en) * 2001-09-06 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
US20030054331A1 (en) 2001-09-14 2003-03-20 Stemsource, Inc. Preservation of non embryonic cells from non hematopoietic tissues
US6638503B2 (en) 2001-11-28 2003-10-28 Maharashtra Association For The Cultivation Of Science Streptomyces megasporus sd5, process for the isolation thereof, novel fibrinolytic enzyme prepared therefrom, process for the production of said enzyme and method of treatment of thrombolytic disorders using said enzyme
EP2305276A3 (de) 2001-12-07 2011-09-21 Cytori Therapeutics, Inc. Zellen aus Lipoaspirat und ihre Verwendung zur Therapie
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
AU2002366802A1 (en) 2001-12-20 2003-07-09 Macropore, Inc. Systems and methods for treating patients with collagen-rich material extracted from adipose tissue
US8313742B2 (en) 2002-03-29 2012-11-20 Depuy Acromed, Inc. Cell-containing bone graft material
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US7992725B2 (en) * 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US6905612B2 (en) * 2003-03-21 2005-06-14 Hanuman Llc Plasma concentrate apparatus and method
US7179391B2 (en) * 2002-05-24 2007-02-20 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
US20040182795A1 (en) 2003-03-21 2004-09-23 Randel Dorian Apparatus and method for concentration of plasma from whole blood
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
EP1549434A1 (de) 2002-05-13 2005-07-06 Becton Dickinson and Company Probenahmesystem mit proteasehemmer
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7304128B2 (en) 2002-06-04 2007-12-04 E.I. Du Pont De Nemours And Company Carbon nanotube binding peptides
US7176034B2 (en) 2002-07-03 2007-02-13 St. Joseph's Healthcare Apparatus and method for filtering biological samples
WO2004009207A1 (en) 2002-07-18 2004-01-29 Hanuman Llc Plasma concentrating apparatus and method
US7077827B2 (en) 2002-08-30 2006-07-18 Christian John Greenfield Syringe for sequential delivery of different fluids
CA2499411C (en) 2002-09-19 2009-10-20 Harvest Technologies Corporation Sterile disposable unit
US20040120942A1 (en) 2002-12-23 2004-06-24 Mcginnis Daniel Device and process for the preparation of autologous thrombin serum
US20040182394A1 (en) 2003-03-21 2004-09-23 Alvey Jeffrey Arthur Powered air purifying respirator system and self contained breathing apparatus
JP4344528B2 (ja) 2003-04-07 2009-10-14 テルモ株式会社 医療用容器および医療用容器の製造方法
WO2004104553A2 (en) 2003-05-19 2004-12-02 Harvest Technologies Corporation Method and apparatus for separating fluid components
WO2004113316A1 (en) 2003-05-20 2004-12-29 Genentech, Inc. Benzofuran inhibitors of factor viia
JP2005013783A (ja) 2003-06-23 2005-01-20 Moriai Seiki Kk 液体遠心分離装置
CN101072572B (zh) * 2003-07-09 2013-12-11 华沙整形外科股份有限公司 富含结缔组织生长成分的骨髓组分的分离及其促进结缔组织形成的用途
US20050084962A1 (en) 2003-08-20 2005-04-21 Bruce Simon Methods of treatment using electromagnetic field stimulated stem cells
US7744869B2 (en) 2003-08-20 2010-06-29 Ebi, Llc Methods of treatment using electromagnetic field stimulated mesenchymal stem cells
DK1670315T3 (en) 2003-09-17 2017-08-07 Cytori Therapeutics Inc PROCEDURES FOR USING FAT FLATED REGENERATIVE CELLS IN THE TREATMENT OF PERFECT Vascular Disease
US20050145187A1 (en) 2003-12-29 2005-07-07 Gray James D. Asset management of livestock in an open range using satellite communications
US7354515B2 (en) 2004-02-23 2008-04-08 Millennium Medical Technologies, Inc. Fluid concentrator
US20060051865A1 (en) 2004-08-31 2006-03-09 Higgins Joel C Systems and methods for isolating stromal cells from adipose tissue and uses thereof
SE0402500D0 (sv) 2004-10-14 2004-10-14 Astra Tech Ab Method and apparatus for autotransfusion
ITRM20040638A1 (it) 2004-12-24 2005-03-24 Advance Holdings Ltd Gel piastrinico semisintetico e metodo per la sua preparazione.
ES2426172T3 (es) 2005-02-07 2013-10-21 Hanuman Llc Dispositivo concentrador de plasma
EP1848474B1 (de) 2005-02-07 2013-06-12 Hanuman LLC Vorrichtung und verfahren mit blutplättchenreichem plasmakonzentrat
ES2426941T3 (es) 2005-02-07 2013-10-25 Hanuman Llc Aparato y procedimiento de concentrados de plasma rico en plaquetas
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US7766900B2 (en) 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US7694828B2 (en) 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US7531355B2 (en) 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
US7771590B2 (en) 2005-08-23 2010-08-10 Biomet Manufacturing Corp. Method and apparatus for collecting biological materials
US8048297B2 (en) 2005-08-23 2011-11-01 Biomet Biologics, Llc Method and apparatus for collecting biological materials
FR2890976B1 (fr) 2005-09-20 2007-12-14 Univ La Reunion Kit pour preparer une composition comprenant des cellules adipocytaires et procede d'obtention de ladite composition
WO2007127841A2 (en) 2006-04-26 2007-11-08 Arteriocyte Medical Systems, Inc. Compositions and methods of preparation thereof
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
CA2866455A1 (en) 2006-09-05 2008-03-13 Maasland N.V. A milking implement
JP2008104789A (ja) 2006-10-27 2008-05-08 Nipro Corp 多血小板血漿分離方法及び多血小板血漿分離装置
US20080164204A1 (en) 2007-01-08 2008-07-10 Mehdi Hatamian Valve for facilitating and maintaining separation of fluids and materials
WO2008100442A1 (en) 2007-02-09 2008-08-21 Biomet Biologics, Inc. Treatment of tissue defects with a therapeutic composition
US8034014B2 (en) 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US7806276B2 (en) 2007-04-12 2010-10-05 Hanuman, Llc Buoy suspension fractionation system
US20080268064A1 (en) 2007-04-25 2008-10-30 Biomet Biologics, Inc. Method for treating cartilage defects
US20080269762A1 (en) 2007-04-25 2008-10-30 Biomet Manufacturing Corp. Method and device for repair of cartilage defects
US7901344B2 (en) 2007-05-11 2011-03-08 Biomet Biologics, Llc Methods of reducing surgical complications in cancer patients
WO2009021257A1 (de) 2007-08-13 2009-02-19 Greiner Bio-One Gmbh Medizinische trenneinrichtung
JP5364102B2 (ja) 2007-12-07 2013-12-11 ハーベスト・テクノロジーズ・コーポレイション 血液成分を分離するための浮動ディスク
US20090192528A1 (en) 2008-01-29 2009-07-30 Biomet Biologics, Inc. Method and device for hernia repair
US8753690B2 (en) 2008-02-27 2014-06-17 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
EP2259774B1 (de) 2008-02-27 2012-12-12 Biomet Biologics, LLC Verfahren und zusammensetzungen zur abgabe eines interleukin-1-rezeptor-antagonisten
WO2009111338A1 (en) 2008-02-29 2009-09-11 Biomet Manufacturing Corp. A system and process for separating a material
US8518272B2 (en) 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8182769B2 (en) 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US8177072B2 (en) 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods

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US8187477B2 (en) 2012-05-29
ES2289306T3 (es) 2008-02-01
WO2003092894A3 (en) 2004-03-25
US7837884B2 (en) 2010-11-23
ATE364446T1 (de) 2007-07-15
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AU2003265160A1 (en) 2003-11-17
US7470371B2 (en) 2008-12-30
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US20050196874A1 (en) 2005-09-08
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US8950586B2 (en) 2015-02-10
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US20070034579A1 (en) 2007-02-15
US20050186120A1 (en) 2005-08-25
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