DE60234583D1 - Analyse von raman-spektralsignalen von ausgewählten augenbereichen - Google Patents

Analyse von raman-spektralsignalen von ausgewählten augenbereichen

Info

Publication number
DE60234583D1
DE60234583D1 DE60234583T DE60234583T DE60234583D1 DE 60234583 D1 DE60234583 D1 DE 60234583D1 DE 60234583 T DE60234583 T DE 60234583T DE 60234583 T DE60234583 T DE 60234583T DE 60234583 D1 DE60234583 D1 DE 60234583D1
Authority
DE
Germany
Prior art keywords
level
raman spectrum
eye
blood
brain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60234583T
Other languages
English (en)
Inventor
James L Lambert
Mark S Borchert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Childrens Hospital Los Angeles
Childrens Hospital Los Angeles Research Institute
Original Assignee
California Institute of Technology CalTech
Childrens Hospital Los Angeles
Childrens Hospital Los Angeles Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech, Childrens Hospital Los Angeles, Childrens Hospital Los Angeles Research Institute filed Critical California Institute of Technology CalTech
Application granted granted Critical
Publication of DE60234583D1 publication Critical patent/DE60234583D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/027—Control of working procedures of a spectrometer; Failure detection; Bandwidth calculation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/656—Raman microprobe
DE60234583T 2001-01-09 2002-01-09 Analyse von raman-spektralsignalen von ausgewählten augenbereichen Expired - Fee Related DE60234583D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/756,897 US6574501B2 (en) 1998-07-13 2001-01-09 Assessing blood brain barrier dynamics or identifying or measuring selected substances or toxins in a subject by analyzing Raman spectrum signals of selected regions in the eye
PCT/US2002/000649 WO2002060321A2 (en) 2001-01-09 2002-01-09 Analysis of raman spectrum signals from selected regions of the eye

Publications (1)

Publication Number Publication Date
DE60234583D1 true DE60234583D1 (de) 2010-01-14

Family

ID=25045516

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60234583T Expired - Fee Related DE60234583D1 (de) 2001-01-09 2002-01-09 Analyse von raman-spektralsignalen von ausgewählten augenbereichen

Country Status (7)

Country Link
US (1) US6574501B2 (de)
EP (1) EP1383417B1 (de)
AT (1) ATE450195T1 (de)
AU (1) AU2002248331A1 (de)
CA (1) CA2438027A1 (de)
DE (1) DE60234583D1 (de)
WO (1) WO2002060321A2 (de)

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Also Published As

Publication number Publication date
ATE450195T1 (de) 2009-12-15
US20010034478A1 (en) 2001-10-25
WO2002060321A3 (en) 2003-11-20
CA2438027A1 (en) 2002-08-08
US6574501B2 (en) 2003-06-03
EP1383417A2 (de) 2004-01-28
EP1383417B1 (de) 2009-12-02
WO2002060321A2 (en) 2002-08-08
AU2002248331A1 (en) 2002-08-12

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