DE60230868D1 - Criptoblockierende antikörper und deren verwendung - Google Patents

Criptoblockierende antikörper und deren verwendung

Info

Publication number
DE60230868D1
DE60230868D1 DE60230868T DE60230868T DE60230868D1 DE 60230868 D1 DE60230868 D1 DE 60230868D1 DE 60230868 T DE60230868 T DE 60230868T DE 60230868 T DE60230868 T DE 60230868T DE 60230868 D1 DE60230868 D1 DE 60230868D1
Authority
DE
Germany
Prior art keywords
criptoblocking
antibodies
criptoblocking antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230868T
Other languages
English (en)
Inventor
Michele Sanicola-Nadel
Kevin Williams
Susan Schiffer
Paul Rayhorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27501437&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60230868(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of DE60230868D1 publication Critical patent/DE60230868D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
DE60230868T 2001-04-26 2002-04-17 Criptoblockierende antikörper und deren verwendung Expired - Lifetime DE60230868D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28678201P 2001-04-26 2001-04-26
US29302001P 2001-05-17 2001-05-17
US30109101P 2001-06-26 2001-06-26
US36700202P 2002-03-22 2002-03-22
PCT/US2002/011950 WO2002088170A2 (en) 2001-04-26 2002-04-17 Cripto blocking antibodies and uses thereof

Publications (1)

Publication Number Publication Date
DE60230868D1 true DE60230868D1 (de) 2009-03-05

Family

ID=27501437

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230868T Expired - Lifetime DE60230868D1 (de) 2001-04-26 2002-04-17 Criptoblockierende antikörper und deren verwendung

Country Status (34)

Country Link
US (6) US7531174B2 (de)
EP (3) EP1974749B1 (de)
JP (4) JP4307845B2 (de)
KR (1) KR100592357B1 (de)
CN (1) CN100352501C (de)
AR (3) AR037223A1 (de)
AT (2) ATE533508T1 (de)
BG (1) BG108363A (de)
BR (1) BR0209254A (de)
CA (2) CA2443840C (de)
CL (1) CL2009002199A1 (de)
CY (1) CY1108960T1 (de)
CZ (1) CZ20033208A3 (de)
DE (1) DE60230868D1 (de)
DK (1) DK1390389T3 (de)
EA (1) EA007469B1 (de)
EE (1) EE200300528A (de)
ES (1) ES2321065T3 (de)
GE (1) GEP20074091B (de)
HK (1) HK1058935A1 (de)
HU (1) HUP0501113A3 (de)
IS (1) IS2662B (de)
MX (1) MXPA03009797A (de)
MY (2) MY157382A (de)
NO (1) NO20034805L (de)
NZ (1) NZ566268A (de)
PL (1) PL207087B1 (de)
PT (1) PT1390389E (de)
RS (2) RS20110024A (de)
SG (1) SG157951A1 (de)
SI (1) SI1390389T1 (de)
SK (1) SK14432003A3 (de)
TR (1) TR200301846T2 (de)
WO (1) WO2002088170A2 (de)

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