DE60228065D1 - Verfahren zur herstellung von mikronadelstrukturen mit sanfter lithographie und photolithographie - Google Patents
Verfahren zur herstellung von mikronadelstrukturen mit sanfter lithographie und photolithographieInfo
- Publication number
- DE60228065D1 DE60228065D1 DE60228065T DE60228065T DE60228065D1 DE 60228065 D1 DE60228065 D1 DE 60228065D1 DE 60228065 T DE60228065 T DE 60228065T DE 60228065 T DE60228065 T DE 60228065T DE 60228065 D1 DE60228065 D1 DE 60228065D1
- Authority
- DE
- Germany
- Prior art keywords
- micromold
- structures
- photolithography
- soft lithography
- micronadel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
- A61B5/1405—Devices for taking blood samples
- A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150274—Manufacture or production processes or steps for blood sampling devices
- A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
- A61B5/150419—Pointed piercing elements, e.g. needles, lancets for piercing the skin comprising means for capillary action
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150977—Arrays of piercing elements for simultaneous piercing
- A61B5/150984—Microneedles or microblades
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
- B81C1/00111—Tips, pillars, i.e. raised structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/055—Microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C2201/00—Manufacture or treatment of microstructural devices or systems
- B81C2201/03—Processes for manufacturing substrate-free structures
- B81C2201/034—Moulding
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/808,534 US6663820B2 (en) | 2001-03-14 | 2001-03-14 | Method of manufacturing microneedle structures using soft lithography and photolithography |
| PCT/US2002/007543 WO2002072189A2 (en) | 2001-03-14 | 2002-03-13 | Method of manufacturing microneedle structures using soft lithography and photolithography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60228065D1 true DE60228065D1 (de) | 2008-09-18 |
Family
ID=25199058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60228065T Expired - Lifetime DE60228065D1 (de) | 2001-03-14 | 2002-03-13 | Verfahren zur herstellung von mikronadelstrukturen mit sanfter lithographie und photolithographie |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6663820B2 (de) |
| EP (1) | EP1377338B9 (de) |
| JP (1) | JP4778669B2 (de) |
| AT (1) | ATE403465T1 (de) |
| CA (1) | CA2436207C (de) |
| DE (1) | DE60228065D1 (de) |
| ES (1) | ES2311615T3 (de) |
| WO (1) | WO2002072189A2 (de) |
Families Citing this family (247)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6256533B1 (en) * | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
| US7131987B2 (en) * | 2000-10-16 | 2006-11-07 | Corium International, Inc. | Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation |
| US7108681B2 (en) | 2000-10-16 | 2006-09-19 | Corium International, Inc. | Microstructures for delivering a composition cutaneously to skin |
| US7828827B2 (en) | 2002-05-24 | 2010-11-09 | Corium International, Inc. | Method of exfoliation of skin using closely-packed microstructures |
| WO2002064193A2 (en) * | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
| US6663820B2 (en) * | 2001-03-14 | 2003-12-16 | The Procter & Gamble Company | Method of manufacturing microneedle structures using soft lithography and photolithography |
| US6753067B2 (en) * | 2001-04-23 | 2004-06-22 | Sipix Imaging, Inc. | Microcup compositions having improved flexure resistance and release properties |
| US6591124B2 (en) | 2001-05-11 | 2003-07-08 | The Procter & Gamble Company | Portable interstitial fluid monitoring system |
| US6793632B2 (en) * | 2001-06-12 | 2004-09-21 | Lifescan, Inc. | Percutaneous biological fluid constituent sampling and measurement devices and methods |
| US6881203B2 (en) * | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
| US20040087992A1 (en) * | 2002-08-09 | 2004-05-06 | Vladimir Gartstein | Microstructures for delivering a composition cutaneously to skin using rotatable structures |
| US20030059344A1 (en) * | 2001-09-24 | 2003-03-27 | Brady Michael D. | Pin plate for use in array printing and method for making the pin plate |
| US7146221B2 (en) * | 2001-11-16 | 2006-12-05 | The Regents Of The University Of California | Flexible electrode array for artifical vision |
| WO2003053514A1 (en) * | 2001-12-19 | 2003-07-03 | Alza Corporation | Reservoir housing having a conductive region integrally formed therein |
| US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
| US6743242B2 (en) * | 2002-02-13 | 2004-06-01 | Qi-Zhao Guo | Dual-use suturing device for suturing wound induced from celioscope surgery |
| US6716754B2 (en) * | 2002-03-12 | 2004-04-06 | Micron Technology, Inc. | Methods of forming patterns and molds for semiconductor constructions |
| US20030186405A1 (en) * | 2002-04-01 | 2003-10-02 | The Ohio State University Research Foundation | Micro/nano-embossing process and useful applications thereof |
| US7060192B2 (en) * | 2002-05-09 | 2006-06-13 | Lifescan, Inc. | Methods of fabricating physiological sample collection devices |
| US7125510B2 (en) * | 2002-05-15 | 2006-10-24 | Zhili Huang | Microstructure fabrication and microsystem integration |
| KR20120087197A (ko) | 2002-07-19 | 2012-08-06 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법 |
| US6805809B2 (en) * | 2002-08-28 | 2004-10-19 | Board Of Trustees Of University Of Illinois | Decal transfer microfabrication |
| AU2003303950A1 (en) * | 2002-09-06 | 2004-11-23 | Derek. J. Hansford | Microfabrication of polymer microparticles |
| US6946362B2 (en) * | 2002-09-06 | 2005-09-20 | Hewlett-Packard Development Company, L.P. | Method and apparatus for forming high surface area material films and membranes |
| IL152912A0 (en) * | 2002-11-18 | 2003-06-24 | Nanopass Ltd | Micro needle systems |
| WO2004113584A1 (en) * | 2002-12-23 | 2004-12-29 | Pirelli Pneumatici S.P.A. | Method dor producing coated metal wire |
| KR100563330B1 (ko) * | 2003-01-16 | 2006-03-22 | 포스트마이크로 주식회사 | Ｌｉｇａ공정을 이용한 폴리머 재질의 미세 바늘 어레이제조방법 |
| EP1443344A1 (de) * | 2003-01-29 | 2004-08-04 | Heptagon Oy | Herstellung von mikrostrukturierten Teilen |
| US7578954B2 (en) * | 2003-02-24 | 2009-08-25 | Corium International, Inc. | Method for manufacturing microstructures having multiple microelements with through-holes |
| US7377840B2 (en) | 2004-07-21 | 2008-05-27 | Neopad Technologies Corporation | Methods for producing in-situ grooves in chemical mechanical planarization (CMP) pads, and novel CMP pad designs |
| US7415299B2 (en) * | 2003-04-18 | 2008-08-19 | The Regents Of The University Of California | Monitoring method and/or apparatus |
| US20060025717A1 (en) * | 2003-04-18 | 2006-02-02 | The Regents Of The University Of California | Method for forming hollow out-of-plane microneedles and devices formed hereby |
| US6808646B1 (en) * | 2003-04-29 | 2004-10-26 | Hewlett-Packard Development Company, L.P. | Method of replicating a high resolution three-dimensional imprint pattern on a compliant media of arbitrary size |
| CN1321706C (zh) * | 2003-05-29 | 2007-06-20 | 财团法人工业技术研究院 | 一种数组式微针软质基材结构及其制造方法 |
| US7572405B2 (en) * | 2003-06-02 | 2009-08-11 | Corium International Inc. | Method for manufacturing microstructures having hollow microelements using fluidic jets during a molding operation |
| US6921670B2 (en) * | 2003-06-24 | 2005-07-26 | Hewlett-Packard Development Company, Lp. | Nanostructure fabrication using microbial mandrel |
| ATE369802T1 (de) * | 2003-06-30 | 2007-09-15 | Alza Corp | Verfahren zum beschichten von mikrovorsprüngen zum durchstechen der haut |
| US20050011858A1 (en) * | 2003-07-16 | 2005-01-20 | Industrial Technology Research Institute | Method for fabricating a hollow micro-needle array |
| JP2007505747A (ja) * | 2003-09-17 | 2007-03-15 | ナノコムス・パテンツ・リミテッド | マイクロ構造デバイス及びその製造方法 |
| US8353861B2 (en) * | 2003-09-18 | 2013-01-15 | Texmac, Inc. | Applicator for applying functional substances into human skin |
| ATE551383T1 (de) | 2003-09-23 | 2012-04-15 | Univ North Carolina | Photohärtbare perfluorpolyether zur verwendung als neue werkstoffe in mikrofluidischen vorrichtungen |
| WO2005060621A2 (en) * | 2003-11-21 | 2005-07-07 | The Regents Of The University Of California | Method and/or apparatus for puncturing a surface for extraction, in situ analysis, and/or substance delivery using microneedles |
| BRPI0417848B1 (pt) | 2003-12-19 | 2019-01-15 | Univ North Carolina State | método para formar uma pluralidade de micro-partículas e/ou nano-partículas, pluralidade de partículas formada pelo método e aparelho para formar uma pluralidade de partículas de acordo com o método |
| US9040090B2 (en) | 2003-12-19 | 2015-05-26 | The University Of North Carolina At Chapel Hill | Isolated and fixed micro and nano structures and methods thereof |
| US8017145B2 (en) * | 2003-12-22 | 2011-09-13 | Conopco, Inc. | Exfoliating personal care wipe article containing an array of projections |
| GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| US8551391B2 (en) * | 2004-02-17 | 2013-10-08 | Avery Dennison Corporation | Method of making microneedles |
| JP2007523771A (ja) * | 2004-02-23 | 2007-08-23 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの成形方法 |
| ATE490567T1 (de) * | 2004-03-08 | 2010-12-15 | Univ Illinois | Mikrofluidische elektrochemische reaktoren |
| CA2560840C (en) | 2004-03-24 | 2014-05-06 | Corium International, Inc. | Transdermal delivery device |
| US20050221112A1 (en) * | 2004-03-31 | 2005-10-06 | Daewoong Suh | Microtools for package substrate patterning |
| US7195733B2 (en) * | 2004-04-27 | 2007-03-27 | The Board Of Trustees Of The University Of Illinois | Composite patterning devices for soft lithography |
| TWI246929B (en) * | 2004-07-16 | 2006-01-11 | Ind Tech Res Inst | Microneedle array device and its fabrication method |
| WO2006018642A1 (en) | 2004-08-16 | 2006-02-23 | Functional Microstructures Limited | Method of producing a microneedle or microimplant |
| US7662545B2 (en) * | 2004-10-14 | 2010-02-16 | The Board Of Trustees Of The University Of Illinois | Decal transfer lithography |
| US7627938B2 (en) * | 2004-10-15 | 2009-12-08 | Board Of Regents, The Univeristy Of Texas System | Tapered hollow metallic microneedle array assembly and method of making and using the same |
| AU2005314151B2 (en) | 2004-12-07 | 2011-09-08 | 3M Innovative Properties Company | Method of molding a microneedle |
| US7288327B2 (en) * | 2004-12-16 | 2007-10-30 | Xerox Corporation | Plated structures or components |
| US7691298B2 (en) * | 2005-01-21 | 2010-04-06 | Wisconsin Alumni Research Foundation | Plastic cantilevers for force microscopy |
| JP4793806B2 (ja) * | 2005-03-22 | 2011-10-12 | Ｔｔｉ・エルビュー株式会社 | イオントフォレーシス装置 |
| WO2006105146A2 (en) | 2005-03-29 | 2006-10-05 | Arkal Medical, Inc. | Devices, systems, methods and tools for continuous glucose monitoring |
| JP2006341089A (ja) * | 2005-05-13 | 2006-12-21 | Fujikura Ltd | 医薬物運搬用器具およびその製造方法 |
| WO2006121110A1 (ja) * | 2005-05-13 | 2006-11-16 | Hisamitsu Pharmaceutical Co., Inc. | 医薬物運搬用器具およびその製造方法 |
| US7442029B2 (en) * | 2005-05-16 | 2008-10-28 | Asml Netherlands B.V. | Imprint lithography |
| JP4646705B2 (ja) * | 2005-06-03 | 2011-03-09 | アルプス電気株式会社 | 金型の製造方法及び成型品の製造方法 |
| AU2006261899B2 (en) | 2005-06-27 | 2012-05-10 | Kindeva Drug Delivery L.P. | Microneedle cartridge assembly and method of applying |
| US20070078414A1 (en) * | 2005-08-05 | 2007-04-05 | Mcallister Devin V | Methods and devices for delivering agents across biological barriers |
| EP2537657A3 (de) | 2005-08-09 | 2016-05-04 | The University of North Carolina At Chapel Hill | Verfahren und Materialien zur Herstellung mikrofluidischer Vorrichtungen |
| WO2007026605A1 (ja) * | 2005-08-30 | 2007-03-08 | Riken | 微細パターン形成方法 |
| US8518069B2 (en) | 2005-09-07 | 2013-08-27 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
| US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| US9358033B2 (en) * | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
| US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
| BRPI0616165A2 (pt) | 2005-09-15 | 2011-06-07 | Tti Ellebeau Inc | dispositivo de iontoforese do tipo de haste |
| JP2009509685A (ja) * | 2005-09-30 | 2009-03-12 | Ｔｔｉ・エルビュー株式会社 | 損傷組織の治癒を増強するための血管新生因子の送達のためのイオントフォレーシス装置及び方法 |
| JP2009509634A (ja) * | 2005-09-30 | 2009-03-12 | Ｔｔｉ・エルビュー株式会社 | 官能基化マイクロニードル経皮薬剤送達システム、装置及び方法 |
| US20080262416A1 (en) * | 2005-11-18 | 2008-10-23 | Duan Daniel C | Microneedle Arrays and Methods of Preparing Same |
| US7885793B2 (en) | 2007-05-22 | 2011-02-08 | International Business Machines Corporation | Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution |
| WO2007075614A1 (en) * | 2005-12-21 | 2007-07-05 | 3M Innovative Properties Company | Microneedle devices |
| KR101157966B1 (ko) * | 2005-12-29 | 2012-06-25 | 엘지디스플레이 주식회사 | 액정표시소자의 제조방법 |
| WO2007079193A2 (en) | 2005-12-30 | 2007-07-12 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
| SG134178A1 (en) * | 2006-01-09 | 2007-08-29 | Agency Science Tech & Res | Microstructure formation technique |
| US7658728B2 (en) * | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
| US9339641B2 (en) | 2006-01-17 | 2016-05-17 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
| US9610459B2 (en) | 2009-07-24 | 2017-04-04 | Emkinetics, Inc. | Cooling systems and methods for conductive coils |
| US7699819B2 (en) | 2006-02-21 | 2010-04-20 | The Hong Kong University Of Science And Technology | Molecular sieve and zeolite microneedles and preparation thereof |
| US20110107473A1 (en) * | 2006-03-15 | 2011-05-05 | Wisconsin Alumni Research Foundation | Diamond-like carbon coated nanoprobes |
| US20100233350A1 (en) * | 2006-03-15 | 2010-09-16 | Boston Scientific Scimed, Inc. | Drug delivery composition and methods of making same using nanofabrication |
| US20080142709A1 (en) * | 2006-03-21 | 2008-06-19 | Anirudha Vishwanath Sumant | MONOLITHIC ta-C NANOPROBES AND ta-C COATED NANOPROBES |
| US20090131959A1 (en) * | 2006-04-20 | 2009-05-21 | Liquidia Technologies Inc. | Biological Vessel Flow Control Devices and Methods |
| JP2007331095A (ja) * | 2006-05-18 | 2007-12-27 | Semiconductor Energy Lab Co Ltd | 微小構造体、マイクロマシンおよび半導体装置、ならびに微小構造体およびマイクロマシンの作製方法 |
| KR101416512B1 (ko) | 2006-05-18 | 2014-07-08 | 가부시키가이샤 한도오따이 에네루기 켄큐쇼 | 미소 구조체, 마이크로머신, 미소 구조체 및 마이크로머신의 제조방법 |
| US20080063866A1 (en) * | 2006-05-26 | 2008-03-13 | Georgia Tech Research Corporation | Method for Making Electrically Conductive Three-Dimensional Structures |
| US20070276318A1 (en) * | 2006-05-26 | 2007-11-29 | Mit, Llp | Iontosonic-microneedle applicator apparatus and methods |
| US20070282246A1 (en) * | 2006-06-05 | 2007-12-06 | Mit, Llp | Iontosonic-microneedle biosensor apparatus and methods |
| KR100857521B1 (ko) * | 2006-06-13 | 2008-09-08 | 엘지디스플레이 주식회사 | 박막트랜지스터 제조용 몰드의 제조방법 및 그 제조장비 |
| KR100827620B1 (ko) * | 2006-07-10 | 2008-05-07 | 삼성전기주식회사 | 임프린트법을 이용한 인쇄회로기판의 제조방법 |
| US8012566B2 (en) * | 2006-07-12 | 2011-09-06 | Hewlett-Packard Development Company, L.P. | Microneedles formed by electroplating and selectively releasing temperature sensitive layers |
| KR100791363B1 (ko) * | 2006-07-12 | 2008-01-03 | 한국과학기술원 | 미세유로 형성물 및 미세유체소자 제조방법 |
| KR100781702B1 (ko) * | 2006-07-21 | 2007-12-03 | 연세대학교 산학협력단 | 중공형 마이크로니들 및 이의 제조방법 |
| JP2008029710A (ja) * | 2006-07-31 | 2008-02-14 | Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai | マイクロニードル型パッチ及びその製造方法 |
| US20080058726A1 (en) * | 2006-08-30 | 2008-03-06 | Arvind Jina | Methods and Apparatus Incorporating a Surface Penetration Device |
| US20080097352A1 (en) * | 2006-09-12 | 2008-04-24 | Beck Patricia A | Methods of fabricating microneedles with bio-sensory functionality |
| JP4888011B2 (ja) * | 2006-09-28 | 2012-02-29 | 凸版印刷株式会社 | 針状体およびその製造方法 |
| JP4888018B2 (ja) * | 2006-09-29 | 2012-02-29 | 凸版印刷株式会社 | 針状体の製造方法及び針状体 |
| CA2665134A1 (en) | 2006-10-02 | 2008-04-10 | Emkinetics, Inc. | Method and apparatus for magnetic induction therapy |
| US10786669B2 (en) | 2006-10-02 | 2020-09-29 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
| US11224742B2 (en) | 2006-10-02 | 2022-01-18 | Emkinetics, Inc. | Methods and devices for performing electrical stimulation to treat various conditions |
| US9005102B2 (en) | 2006-10-02 | 2015-04-14 | Emkinetics, Inc. | Method and apparatus for electrical stimulation therapy |
| JP5023671B2 (ja) * | 2006-11-22 | 2012-09-12 | 凸版印刷株式会社 | 針状体の製造方法 |
| CA2671069A1 (en) * | 2006-12-01 | 2008-06-12 | Tti Ellebeau, Inc. | Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices |
| KR100790899B1 (ko) * | 2006-12-01 | 2008-01-03 | 삼성전자주식회사 | 얼라인 마크가 형성된 템플릿 및 그 제조 방법 |
| US8877074B2 (en) * | 2006-12-15 | 2014-11-04 | The Regents Of The University Of California | Methods of manufacturing microdevices in laminates, lead frames, packages, and printed circuit boards |
| TW200829215A (en) * | 2007-01-03 | 2008-07-16 | Univ Nat Chiao Tung | Micro probe array and manufacturing method of the trans-print mold thereof |
| CA2676221C (en) | 2007-01-22 | 2016-12-20 | Corium International, Inc. | Applicators for microneedles |
| US7713196B2 (en) | 2007-03-09 | 2010-05-11 | Nellcor Puritan Bennett Llc | Method for evaluating skin hydration and fluid compartmentalization |
| US8560059B2 (en) * | 2007-03-09 | 2013-10-15 | Covidien Lp | System and methods for optical sensing and drug delivery using microneedles |
| US9114238B2 (en) | 2007-04-16 | 2015-08-25 | Corium International, Inc. | Solvent-cast microprotrusion arrays containing active ingredient |
| JP2009039171A (ja) * | 2007-08-06 | 2009-02-26 | Dai Ichi Kasei Kk | 微細針形状突起物及びその成形金型及びその製造方法 |
| JP5205016B2 (ja) * | 2007-09-04 | 2013-06-05 | 凸版印刷株式会社 | 針状体、針状体製造方法 |
| US9549746B2 (en) * | 2007-09-28 | 2017-01-24 | The Queen's University Of Belfast | Delivery device and method |
| US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
| WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
| US8378046B2 (en) | 2007-10-19 | 2013-02-19 | 3M Innovative Properties Company | High refractive index pressure-sensitive adhesives |
| KR101545365B1 (ko) | 2007-10-30 | 2015-08-18 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 고 굴절률 접착제 |
| US20110104321A1 (en) * | 2007-11-01 | 2011-05-05 | Jun-Ying Zhang | Method for replicating master molds |
| AU2008341030B2 (en) | 2007-12-24 | 2014-04-17 | Vaxxas Pty Limited | Coating method |
| AU2009212106B9 (en) * | 2008-02-07 | 2014-05-22 | Vaxxas Pty Limited | Patch production |
| WO2009113519A1 (ja) * | 2008-03-12 | 2009-09-17 | 富士フイルム株式会社 | 凹形アレイモールドの原版、凹形アレイモールド及び針状アレイシートの製造方法 |
| KR101457528B1 (ko) * | 2008-05-15 | 2014-11-04 | 삼성디스플레이 주식회사 | 임프린트 기판의 제조방법 및 임프린팅 방법 |
| JP5584202B2 (ja) * | 2008-05-21 | 2014-09-03 | セラジェクト， インコーポレイテッド | 固溶体穿孔器パッチの製造方法及びその使用 |
| JP2010009729A (ja) * | 2008-06-30 | 2010-01-14 | Toshiba Corp | インプリント用スタンパ、インプリント用スタンパの製造方法、磁気記録媒体、磁気記録媒体の製造方法及び磁気ディスク装置 |
| US20100028604A1 (en) * | 2008-08-01 | 2010-02-04 | The Ohio State University | Hierarchical structures for superhydrophobic surfaces and methods of making |
| WO2010078323A1 (en) * | 2008-12-29 | 2010-07-08 | Sung-Yun Kwon | Method of manufacturing solid solution peforator patches and uses thereof |
| KR101433292B1 (ko) * | 2009-02-17 | 2014-08-22 | 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 | 마이크로구조 제조방법 |
| EP2398638A1 (de) * | 2009-02-17 | 2011-12-28 | The Board Of Trustees Of The UniversityOf Illinois | Flexible mikrostrukturierte superhydrophobe materialien |
| US8465812B2 (en) | 2009-03-23 | 2013-06-18 | The Boeing Company | Durable transparent intelligent coatings for polymeric transparencies |
| US8814954B2 (en) * | 2009-05-08 | 2014-08-26 | Hoowaki, Llc | Method of manufacturing products having a metal surface |
| US20100323248A1 (en) * | 2009-06-17 | 2010-12-23 | Battelle Energy Alliance, Llc | Structures having one or more super-hydrophobic surfaces and methods of forming same |
| US8147704B2 (en) * | 2009-07-10 | 2012-04-03 | Korea University Research And Business Foundation | Wide area stamp for antireflective surface |
| KR101261466B1 (ko) * | 2009-07-17 | 2013-05-10 | 한국전자통신연구원 | 할로우 마이크로 니들의 제조 방법 |
| CA2768835A1 (en) * | 2009-07-23 | 2011-01-27 | Emkinetics, Inc. | Method and apparatus for magnetic induction therapy |
| US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
| US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
| US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
| AU2010313487A1 (en) | 2009-10-26 | 2012-05-24 | Emkinetics, Inc. | Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues |
| KR101666214B1 (ko) * | 2009-11-05 | 2016-10-14 | 삼성디스플레이 주식회사 | 이방성 도전 필름, 이의 제조 방법 및 이를 포함하는 표시 장치 |
| IT1397018B1 (it) * | 2009-11-12 | 2012-12-20 | St Microelectronics Rousset | Procedimento per la realizzazione di un dispositivo a microaghi, in particolare per uso sensoristico |
| DE112009005487A5 (de) * | 2009-12-29 | 2012-10-04 | Werner Suedes | Verfahren zur Herstellung eines Verbundkörpers mit einer freitragenden Fläche |
| US9526883B2 (en) * | 2010-04-28 | 2016-12-27 | Kimberly-Clark Worldwide, Inc. | Composite microneedle array including nanostructures thereon |
| EP2563451B1 (de) | 2010-04-28 | 2017-11-01 | Kimberly-Clark Worldwide, Inc. | Medizinische vorrichtungen zur abgabe von sirna |
| MX2012012567A (es) | 2010-04-28 | 2012-11-21 | Kimberly Clark Co | Metodo para aumentar la permeabilidad de una barrera epitelial. |
| DK2563450T3 (da) | 2010-04-28 | 2017-11-13 | Kimberly Clark Co | Apparat til administration af rheumatoid-arthritis-medikament |
| AU2011248108B2 (en) | 2010-05-04 | 2016-05-26 | Corium Pharma Solutions, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
| US8588884B2 (en) | 2010-05-28 | 2013-11-19 | Emkinetics, Inc. | Microneedle electrode |
| US9943673B2 (en) | 2010-07-14 | 2018-04-17 | Vaxxas Pty Limited | Patch applying apparatus |
| US9168679B2 (en) * | 2010-07-16 | 2015-10-27 | Northwestern University | Programmable soft lithography: solvent-assisted nanoscale embossing |
| TWI486304B (zh) * | 2010-08-13 | 2015-06-01 | Nat Univ Tsing Hua | 可交錯固定之奈微米結構件組及其結構件 |
| WO2012026973A2 (en) | 2010-08-23 | 2012-03-01 | Carnegie Mellon University | Micro-fiber arrays with tip coating and transfer method for preparing same |
| TWI415730B (zh) * | 2011-02-17 | 2013-11-21 | The system of masking | |
| CN102745644B (zh) * | 2011-04-22 | 2015-06-24 | 国家纳米科学中心 | 利用高压静电纺丝翻模在材料表面得到微纳米结构的方法 |
| US9104100B2 (en) | 2011-06-08 | 2015-08-11 | 3M Innovative Properties Company | Photoresists containing polymer-tethered nanoparticles |
| US8875356B2 (en) | 2011-10-06 | 2014-11-04 | Intercontinental Great Brands Llc | Mechanical and adhesive based reclosable fasteners |
| AU2012323782B2 (en) * | 2011-10-12 | 2017-04-06 | Vaxxas Pty Limited | Delivery device |
| JP6100271B2 (ja) | 2011-10-27 | 2017-03-22 | キンバリー クラーク ワールドワイド インコーポレイテッド | 高粘性生理活性薬剤の経皮的送達 |
| DK3542851T3 (da) | 2011-10-27 | 2022-03-14 | Sorrento Therapeutics Inc | Implanterbare indretninger til levering af bioaktive midler |
| US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
| SG11201405643RA (en) * | 2012-03-16 | 2014-10-30 | Univ Singapore | A novel method to fabricate polymeric microneedles |
| CA3077452C (en) | 2012-05-01 | 2022-08-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
| SG11201408221YA (en) | 2012-06-15 | 2015-01-29 | Univ Washington Ct Commerciali | Microstructure-based wound closure devices |
| JP5593355B2 (ja) * | 2012-07-23 | 2014-09-24 | 凸版印刷株式会社 | 針状体および針状体製造方法 |
| CA2892587A1 (en) | 2012-12-14 | 2014-06-19 | Mindera Corporation | Methods and devices for detection and acquisition of biomarkers |
| US10821276B2 (en) * | 2012-12-14 | 2020-11-03 | The Trustees Of Columbia University In The City Of New York | System and method to locally deliver therapeutic agent to inner ear |
| CN102988039A (zh) * | 2012-12-17 | 2013-03-27 | 中国科学院半导体研究所 | 制作基于微针阵列皮肤干电极的方法 |
| MX2015008157A (es) | 2012-12-21 | 2016-02-22 | Corium Int Inc | Microarreglo para la entrega de agente terapeutico y metodos de uso. |
| EP4094799A1 (de) | 2013-03-12 | 2022-11-30 | Corium, Inc. | Mikroprojektionsapplikatoren |
| CA2903583C (en) | 2013-03-15 | 2021-12-28 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| JP2016514133A (ja) | 2013-03-15 | 2016-05-19 | コリウム インターナショナル， インコーポレイテッド | ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法 |
| US9250357B2 (en) | 2013-03-15 | 2016-02-02 | Johnson & Johnson Vision Care, Inc. | Silicone-containing contact lens having reduced amount of silicon on the surface |
| RU2711567C2 (ru) | 2013-03-15 | 2020-01-17 | Кориум, ИНК. | Микрочип для доставки лекарственного средства и способы его использования |
| US10195409B2 (en) | 2013-03-15 | 2019-02-05 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
| CN103231518B (zh) * | 2013-03-22 | 2015-03-11 | 南京航空航天大学 | 一种聚二甲基硅氧烷阵列微孔薄膜制备方法 |
| WO2015016235A1 (ja) * | 2013-07-30 | 2015-02-05 | Ａｓｔｉ株式会社 | マイクロニードルアレイとマイクロニードルアレイ製造方法 |
| US10840400B2 (en) * | 2013-08-29 | 2020-11-17 | Taiwan Semiconductor Manufacturing Co., Ltd. | Photovoltaic device with back reflector |
| US11185271B2 (en) | 2013-09-13 | 2021-11-30 | University Of Utah Research Foundation | Methods of making micro-molded electrodes and arrays |
| KR101741668B1 (ko) * | 2013-11-27 | 2017-05-31 | 부산대학교 산학협력단 | 미세 메쉬 구조물 제작 방법 |
| CN103767704B (zh) * | 2014-01-20 | 2015-08-26 | 上海交通大学 | 一种用于脑电测量的准干电极及其制备方法 |
| US9212045B1 (en) | 2014-07-31 | 2015-12-15 | Infineon Technologies Ag | Micro mechanical structure and method for fabricating the same |
| US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
| WO2016039333A1 (ja) * | 2014-09-08 | 2016-03-17 | 株式会社かいわ | 穿刺器具 |
| JP5967595B2 (ja) * | 2014-09-08 | 2016-08-10 | 株式会社かいわ | 穿刺器具 |
| WO2016072350A1 (ja) | 2014-11-07 | 2016-05-12 | 凸版印刷株式会社 | 経皮投薬用針集成体及びその製造方法 |
| JP6906885B2 (ja) | 2014-11-14 | 2021-07-21 | ロレアル | しわを減少させるためのマイクロニードルシート |
| WO2016084701A1 (ja) * | 2014-11-28 | 2016-06-02 | テルモ株式会社 | マイクロニードルデバイス |
| CA3204959A1 (en) | 2015-02-02 | 2016-08-11 | Vaxxas Pty Limited | Microprojection array applicator and method |
| US20180029288A1 (en) * | 2015-02-16 | 2018-02-01 | Basf Se | Process for producing structured polymer surfaces |
| US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
| WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| US10098574B1 (en) | 2015-07-07 | 2018-10-16 | Verily Life Sciences Llc | Porous microneedles through sacrificial sugar incorporation, analyte detection system, and method for intradermal optode nanosensor implantation |
| US11103259B2 (en) | 2015-09-18 | 2021-08-31 | Vaxxas Pty Limited | Microprojection arrays with microprojections having large surface area profiles |
| WO2017066768A1 (en) | 2015-10-16 | 2017-04-20 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices |
| US11744889B2 (en) | 2016-01-05 | 2023-09-05 | University of Pittsburgh—of the Commonwealth System of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
| JP2019513070A (ja) | 2016-03-01 | 2019-05-23 | キトテック メディカル， インコーポレイテッド | 創傷閉鎖のための微細構造に基づくシステム、装置および方法 |
| KR20190040010A (ko) | 2016-08-22 | 2019-04-16 | 라모트 앳 텔-아비브 유니버시티 리미티드 | 생분석물 검출을 위한 방법 및 시스템 |
| KR20190038660A (ko) * | 2016-08-22 | 2019-04-08 | 라모트 앳 텔-아비브 유니버시티 리미티드 | 피하 센싱을 위한 방법 및 시스템 |
| JP7114094B2 (ja) | 2016-12-22 | 2022-08-08 | オハイオ・ステイト・イノベーション・ファウンデーション | ナノチャネルに基づくカーゴ送達のための相互貫入マイクロ構造体 |
| EP3576833A1 (de) * | 2017-01-31 | 2019-12-11 | SABIC Global Technologies B.V. | Verwendung einer folie zur bereitstellung einer vorform für mikrospritzgiessverfahren |
| DK3606760T3 (da) | 2017-03-31 | 2023-11-06 | Vaxxas Pty Ltd | Indretning og fremgangsmåde til belægning af overflader |
| US11175128B2 (en) | 2017-06-13 | 2021-11-16 | Vaxxas Pty Limited | Quality control of substrate coatings |
| EP4218893A1 (de) | 2017-08-04 | 2023-08-02 | Vaxxas Pty Limited | Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map) |
| CN107994099B (zh) * | 2017-11-23 | 2019-08-09 | 西北工业大学 | 基于二维硒化镓材料场效应晶体管制备方法 |
| KR102139335B1 (ko) * | 2017-11-24 | 2020-07-29 | 주식회사 엘지생활건강 | 니들 팁에 코팅부를 보유하는 마이크로니들을 제조하는 방법 및 장치 |
| EP3494875A1 (de) * | 2017-12-11 | 2019-06-12 | ETH Zurich | Sensorvorrichtung zur detektion eines elektrischen signals |
| US11844919B2 (en) | 2018-01-03 | 2023-12-19 | The Trustees Of Columbia University In The City Of New York | Microneedle for local delivery of therapeutic agent |
| US10980448B2 (en) * | 2018-05-16 | 2021-04-20 | International Business Machines Corporation | Electrically functional polymer microneedle array |
| WO2020005973A1 (en) * | 2018-06-25 | 2020-01-02 | Corium, Inc. | Hybrid method of forming microstructure array molds, methods of making microstructure arrays, and methods of use |
| WO2020069567A1 (en) * | 2018-10-02 | 2020-04-09 | WearOptimo Pty Ltd | Electrode arrangement |
| KR102175312B1 (ko) * | 2018-10-08 | 2020-11-06 | 연세대학교 산학협력단 | 마이크로 구조체 |
| US11482979B2 (en) | 2018-12-03 | 2022-10-25 | X Display Company Technology Limited | Printing components over substrate post edges |
| US11528808B2 (en) | 2018-12-03 | 2022-12-13 | X Display Company Technology Limited | Printing components to substrate posts |
| CN110193097A (zh) * | 2019-03-19 | 2019-09-03 | 厦门理工学院 | 一种三维骨细胞主动接种方法、三维骨细胞主动接种支架及其制备方法 |
| CN110026616A (zh) * | 2019-05-27 | 2019-07-19 | 吉林大学 | 一种微结构阵列表面高效成形机床及成形方法 |
| WO2020257548A1 (en) * | 2019-06-21 | 2020-12-24 | Microneedles Inc | Microneedle patch and fabrication device for production of multilayered microneedles |
| JP2022552622A (ja) * | 2019-09-20 | 2022-12-19 | ナショナル サイエンス アンド テクノロジー デヴェロップメント エージェンシー | マイクロニードルを製造する方法 |
| WO2021066755A2 (en) * | 2019-09-30 | 2021-04-08 | National Science And Technology Development Agency | Manufacturing process of high density microneedles |
| CN112038776B (zh) * | 2020-09-09 | 2022-02-15 | 哈尔滨工业大学 | 一种可拉伸弹性十字超材料的制备方法 |
| CN112373061B (zh) * | 2020-10-13 | 2022-04-29 | 航天特种材料及工艺技术研究所 | 一种复合材料构件及其制造方法 |
| WO2022086754A1 (en) * | 2020-10-19 | 2022-04-28 | Raico International, Llc | Surgical instruments for a trabeculotomy procedure |
| WO2022115714A1 (en) * | 2020-11-30 | 2022-06-02 | Mindera Corporation | Microneedle devices and methods, and skin condition assays |
| CN114660140B (zh) | 2020-12-23 | 2024-02-23 | 北京京东方技术开发有限公司 | 生物检测装置、生物芯片、微电极结构及其制备方法 |
| CN112897455A (zh) * | 2021-01-20 | 2021-06-04 | 西安应用光学研究所 | 一种基于icp刻蚀的连续曲面三维微结构制备方法 |
| CN112794277A (zh) * | 2021-03-05 | 2021-05-14 | 深圳清华大学研究院 | 一种大尺度超滑器件及其加工制作方法 |
| CN113069683B (zh) * | 2021-04-07 | 2022-11-22 | 中国人民解放军军事科学院军事医学研究院 | 一种用于创面修复的可溶性微针贴片的制备方法 |
| CN113460950B (zh) * | 2021-07-02 | 2024-04-02 | 杭州电子科技大学温州研究院有限公司 | 用于心血管疾病监测的柔性可穿戴心电极及其制备方法 |
| CA3226577A1 (en) | 2021-07-07 | 2023-01-12 | The Regents Of The University Of California | Wearable, non-intrusive microneedle sensor |
| CN113927896A (zh) * | 2021-09-08 | 2022-01-14 | 兰州大学 | 一种基于3d打印技术的pdms微针二次母板转写工艺 |
| CN113788453B (zh) * | 2021-09-14 | 2023-06-30 | 深圳清华大学研究院 | 一种超滑岛推动装置和超滑岛的处理方法 |
| CN113777145A (zh) * | 2021-09-14 | 2021-12-10 | 北京大学 | 一种微针生物传感器制造方法 |
| WO2023159181A1 (en) | 2022-02-18 | 2023-08-24 | Kitotech Medical, Inc. | Force modulating deep skin staples and instruments |
| CN114748779A (zh) * | 2022-04-01 | 2022-07-15 | 杭州恒升医学科技有限公司 | 一种微针及其制造工艺 |
| CN114768080B (zh) * | 2022-04-19 | 2024-03-15 | 沈燕萍 | 一种多通道微针及其制造方法 |
| CN115227956A (zh) * | 2022-07-26 | 2022-10-25 | 空芯微医疗科技(上海)有限责任公司 | 空心微针的制备方法 |
| CN117867499A (zh) * | 2022-09-30 | 2024-04-12 | 西安交通大学 | 具有强稳定性的涂层结构 |
Family Cites Families (143)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1770632A (en) * | 1928-07-02 | 1930-07-15 | Arthur E Smith | Ampul syringe |
| BE541794A (de) | 1954-10-04 | |||
| US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
| DE2319591C2 (de) | 1973-04-18 | 1982-02-25 | Kirchner & Wilhelm, 7000 Stuttgart | Medizinischer Apparat |
| FR2232331B1 (de) | 1973-06-06 | 1978-03-24 | Guerin A Ets | |
| AT347283B (de) | 1975-03-07 | 1978-12-27 | Collo Gmbh | Schaumstoffkoerper fuer reinigungs-, scheuer- und/oder polierzwecke u. dgl. |
| US4180232A (en) | 1977-01-13 | 1979-12-25 | Hardigg James S | Truss panel mold |
| US4381963A (en) | 1980-07-30 | 1983-05-03 | The University Of Rochester | Micro fabrication molding process |
| US4585991A (en) | 1982-06-03 | 1986-04-29 | Texas Instruments Incorporated | Solid state multiprobe testing apparatus |
| FR2535602B1 (fr) | 1982-11-05 | 1986-06-13 | Stallergenes Lab | Dispositif scarificateur |
| US5591123A (en) | 1983-08-18 | 1997-01-07 | Drug Delivery Systems Inc. | Programmable control mounting system for transdermal drug applicator |
| US4708716A (en) | 1983-08-18 | 1987-11-24 | Drug Delivery Systems Inc. | Transdermal drug applicator |
| US4583982A (en) | 1984-08-24 | 1986-04-22 | Vlock D G | Fluid dispenser |
| US5135477A (en) | 1984-10-29 | 1992-08-04 | Medtronic, Inc. | Iontophoretic drug delivery |
| US4784737A (en) | 1986-04-18 | 1988-11-15 | The United States Department Of Energy | Electromicroinjection of particles into living cells |
| US4837049A (en) | 1986-06-17 | 1989-06-06 | Alfred E. Mann Foundation For Scientific Research | Method of making an electrode array |
| US5362307A (en) | 1989-01-24 | 1994-11-08 | The Regents Of The University Of California | Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance |
| US5198192A (en) | 1988-05-18 | 1993-03-30 | Inax Corporation | Apparatus for detecting ingredient in urine, a toilet stool equipped with a urine detecting device and a room for urine detecting facility |
| GB2221394B (en) | 1988-08-05 | 1992-03-04 | Eilert Eilertsen | An injection device |
| SU1667864A1 (ru) | 1989-03-23 | 1991-08-07 | Опытный завод энергетического машиностроения | Электростимул тор |
| US5134079A (en) | 1989-03-27 | 1992-07-28 | International Technidyne Corp. | Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling |
| US5531675A (en) * | 1989-05-10 | 1996-07-02 | Yoo; Tae W. | Micro-acupuncture needle for a finger of a hand |
| CA2016900A1 (en) | 1989-07-06 | 1991-01-06 | Ronald J. Filipski | Tines structure in clinical applicator |
| EP0429842B1 (de) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten |
| US5215088A (en) | 1989-11-07 | 1993-06-01 | The University Of Utah | Three-dimensional electrode device |
| US5697901A (en) | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| US5162043A (en) | 1990-03-30 | 1992-11-10 | Alza Corporation | Iontophoretic delivery device |
| US5156591A (en) | 1990-12-13 | 1992-10-20 | S. I. Scientific Innovations Ltd. | Skin electrode construction and transdermal drug delivery device utilizing same |
| US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
| US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
| TW279133B (de) | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
| US5158073A (en) * | 1990-12-18 | 1992-10-27 | Bukowski Voytek Z | Acupressure foot massage mat |
| US5312456A (en) | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
| TW273531B (en) * | 1991-08-14 | 1996-04-01 | Chicopee | Textile-like apertured plastic films |
| US5256360A (en) | 1992-03-25 | 1993-10-26 | Panasonic Technologies, Inc. | Method of manufacturing a precision micro-filter |
| IE930532A1 (en) | 1993-07-19 | 1995-01-25 | Elan Med Tech | Liquid material dispenser and valve |
| US5318557A (en) | 1992-07-13 | 1994-06-07 | Elan Medical Technologies Limited | Medication administering device |
| US5250067A (en) * | 1992-11-30 | 1993-10-05 | Ala Gelfer | Body treatment pad having a multiple number of sharpened skin-penetration protuberances |
| US5383512A (en) | 1993-01-27 | 1995-01-24 | Midwest Research Institute | Method for fabricating a substrate having spaced apart microcapillaries thereon |
| IE68890B1 (en) | 1993-04-08 | 1996-07-24 | Elan Med Tech | Intradermal delivery device |
| US5728089A (en) * | 1993-06-04 | 1998-03-17 | The Regents Of The University Of California | Microfabricated structure to be used in surgery |
| US5320600A (en) * | 1993-06-14 | 1994-06-14 | Lambert Wm S | Plural content container for simultaneous ejection |
| CA2132277C (en) | 1993-10-22 | 2005-05-10 | Giorgio Cirelli | Injection device |
| US5536263A (en) * | 1994-03-30 | 1996-07-16 | Lectec Corporation | Non-occulusive adhesive patch for applying medication to the skin |
| US5611806A (en) | 1994-05-23 | 1997-03-18 | Samsung Electro-Mechanics Co., Ltd. | Skin perforating device for transdermal medication |
| KR0134151B1 (ko) | 1994-05-23 | 1998-04-14 | 이형도 | 인슐린 패치 |
| CA2149836C (en) | 1994-05-23 | 1999-07-06 | Sang Bae Choi | Perforating device for dermal administration |
| US5512219A (en) * | 1994-06-03 | 1996-04-30 | Reflexite Corporation | Method of casting a microstructure sheet having an array of prism elements using a reusable polycarbonate mold |
| US5591139A (en) | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
| US5487726A (en) * | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
| US5771890A (en) | 1994-06-24 | 1998-06-30 | Cygnus, Inc. | Device and method for sampling of substances using alternating polarity |
| US5498235A (en) | 1994-09-30 | 1996-03-12 | Becton Dickinson And Company | Iontophoresis assembly including patch/controller attachment |
| US5551953A (en) | 1994-10-31 | 1996-09-03 | Alza Corporation | Electrotransport system with remote telemetry link |
| IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
| US6120488A (en) | 1994-11-28 | 2000-09-19 | The Procter & Gamble Company | Absorbent articles having cuffs and topsheet with skin care composition(s) disposed thereon |
| WO1996017648A1 (de) | 1994-12-09 | 1996-06-13 | Novartis Ag | Transdermales system |
| AU5740496A (en) | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
| WO1996037256A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
| DE19525607A1 (de) | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
| JP2713255B2 (ja) | 1995-08-11 | 1998-02-16 | 日本電気株式会社 | 浸出液吸引装置 |
| IE77523B1 (en) | 1995-09-11 | 1997-12-17 | Elan Med Tech | Medicament delivery device |
| US5735273A (en) | 1995-09-12 | 1998-04-07 | Cygnus, Inc. | Chemical signal-impermeable mask |
| US5645977A (en) | 1995-09-22 | 1997-07-08 | Industrial Technology Research Institute | Method of making molds for manufacturing multiple-lead microstructures |
| US5658515A (en) | 1995-09-25 | 1997-08-19 | Lee; Abraham P. | Polymer micromold and fabrication process |
| JPH09215755A (ja) | 1996-02-09 | 1997-08-19 | Poritoronikusu:Kk | 皮接治療具 |
| US5948488A (en) | 1996-04-30 | 1999-09-07 | 3M Innovative Properties Company | Glittering cube-corner article |
| ATE234129T1 (de) | 1996-06-18 | 2003-03-15 | Alza Corp | Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten |
| DE19624578A1 (de) | 1996-06-20 | 1998-01-08 | Nancy L Divers | Vorrichtung zur Hautpflege |
| US6183434B1 (en) * | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
| ATE231015T1 (de) | 1996-09-17 | 2003-02-15 | Deka Products Lp | System zur medikamentenabgabe durch transport |
| US5873849A (en) * | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
| US5928207A (en) * | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
| US6216034B1 (en) * | 1997-08-01 | 2001-04-10 | Genetronics, Inc. | Method of programming an array of needle electrodes for electroporation therapy of tissue |
| US6241701B1 (en) * | 1997-08-01 | 2001-06-05 | Genetronics, Inc. | Apparatus for electroporation mediated delivery of drugs and genes |
| US6055453A (en) * | 1997-08-01 | 2000-04-25 | Genetronics, Inc. | Apparatus for addressing needle array electrodes for electroporation therapy |
| US6047208A (en) | 1997-08-27 | 2000-04-04 | Becton, Dickinson And Company | Iontophoretic controller |
| US20010023324A1 (en) | 1997-11-03 | 2001-09-20 | Allan Pronovost | Glucose detector and method for diagnosing diabetes |
| US5938684A (en) * | 1997-12-09 | 1999-08-17 | Sierra Self Healing Products, Inc. | Accupressure device for therapeutic relief |
| US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
| DK1037686T3 (da) | 1997-12-11 | 2006-01-02 | Alza Corp | Apparat til forögelse af transdermal gennemströmning af midler |
| PT1037687E (pt) | 1997-12-11 | 2008-12-17 | Alza Corp | Dispositivo para melhoramento de fluxo transdérmico de agente |
| ATE221400T1 (de) * | 1997-12-11 | 2002-08-15 | Alza Corp | Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses |
| US6778853B1 (en) * | 1997-12-17 | 2004-08-17 | University Of South Florida | Electroporation device |
| US6135990A (en) | 1997-12-17 | 2000-10-24 | University Of South Florida | Electroporation device and method |
| US6024553A (en) * | 1997-12-22 | 2000-02-15 | Mcneil-Ppc, Inc. | Apparatus for supporting a starting web during formation of the apertured web |
| US6106751A (en) | 1998-03-18 | 2000-08-22 | The Regents Of The University Of California | Method for fabricating needles via conformal deposition in two-piece molds |
| US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
| EP1190229B1 (de) * | 1998-05-22 | 2011-10-26 | California Institute Of Technology | Miniaturisierter zellsortierer |
| US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
| AU767122B2 (en) | 1998-06-10 | 2003-10-30 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
| GB9815819D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Transferring materials into cells and a microneedle array |
| GB9815820D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Improvements relating to micro-machining |
| US6532386B2 (en) * | 1998-08-31 | 2003-03-11 | Johnson & Johnson Consumer Companies, Inc. | Electrotransort device comprising blades |
| US6036659A (en) | 1998-10-09 | 2000-03-14 | Flexsite Diagnostics, Inc. | Collection device for biological samples and methods of use |
| US6038465A (en) | 1998-10-13 | 2000-03-14 | Agilent Technologies, Inc. | Telemedicine patient platform |
| US6611706B2 (en) * | 1998-11-09 | 2003-08-26 | Transpharma Ltd. | Monopolar and bipolar current application for transdermal drug delivery and analyte extraction |
| EP1003078A3 (de) * | 1998-11-17 | 2001-11-07 | Corning Incorporated | Verfahren zur Vervielfältigung eines Nanomusters |
| CA2352974A1 (en) | 1998-12-18 | 2000-06-22 | John H. Livingston | Insertion sets with micro-piercing members for use with medical devices and methods of using the same |
| JP2000194142A (ja) * | 1998-12-25 | 2000-07-14 | Fujitsu Ltd | パタ―ン形成方法及び半導体装置の製造方法 |
| JP2000232095A (ja) * | 1999-02-12 | 2000-08-22 | Nippon Telegr & Teleph Corp <Ntt> | 半導体表面の微細パターン形成方法 |
| US6689103B1 (en) * | 1999-05-07 | 2004-02-10 | Scimed Life System, Inc. | Injection array apparatus and method |
| JP2000323461A (ja) * | 1999-05-11 | 2000-11-24 | Nec Corp | 微細パターン形成装置、その製造方法、および形成方法 |
| NO311797B1 (no) * | 1999-05-12 | 2002-01-28 | Thin Film Electronics Asa | Fremgangsmåter til mönstring av polymerfilmer og anvendelse av fremgangsmåtene |
| JP4114761B2 (ja) * | 1999-05-14 | 2008-07-09 | 国立大学法人群馬大学 | 情報記録ディスク用スタンパー、その製造方法、情報記録ディスク、および情報記録ディスク製造方法 |
| US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
| DE60044084D1 (de) | 1999-06-04 | 2010-05-12 | Georgia Tech Res Inst | Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten |
| US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
| US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
| US6312612B1 (en) | 1999-06-09 | 2001-11-06 | The Procter & Gamble Company | Apparatus and method for manufacturing an intracutaneous microneedle array |
| DE19927359A1 (de) * | 1999-06-16 | 2000-12-21 | Creavis Tech & Innovation Gmbh | Elektrophoretische Displays aus lichtstreuenden Trägermaterialien |
| ATE450895T1 (de) * | 1999-07-21 | 2009-12-15 | E Ink Corp | Bevorzugte methode, elektrische leiterbahnen für die kontrolle eines elektronischen displays herzustellen |
| US6623457B1 (en) | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
| US6835184B1 (en) | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
| US6355054B1 (en) * | 1999-11-05 | 2002-03-12 | Ceramoptec Industries, Inc. | Laser system for improved transbarrier therapeutic radiation delivery |
| US6511463B1 (en) * | 1999-11-18 | 2003-01-28 | Jds Uniphase Corporation | Methods of fabricating microneedle arrays using sacrificial molds |
| DE60024312T2 (de) * | 1999-12-10 | 2006-08-17 | Alza Corp., Mountain View | Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür |
| ES2238333T3 (es) * | 1999-12-10 | 2005-09-01 | Alza Corporation | Aparato de tratamiento dermico para la administracion prolongada de farmacos por via transdermica. |
| EP1239775B1 (de) * | 1999-12-16 | 2005-03-16 | ALZA Corporation | Vorrichtung zur erhöhung des transdermalen flusses von probenwirkstoffen |
| US6406638B1 (en) * | 2000-01-06 | 2002-06-18 | The Regents Of The University Of California | Method of forming vertical, hollow needles within a semiconductor substrate, and needles formed thereby |
| US6375627B1 (en) | 2000-03-02 | 2002-04-23 | Agilent Technologies, Inc. | Physiological fluid extraction with rapid analysis |
| US6558361B1 (en) * | 2000-03-09 | 2003-05-06 | Nanopass Ltd. | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems |
| US6629949B1 (en) | 2000-05-08 | 2003-10-07 | Sterling Medivations, Inc. | Micro infusion drug delivery device |
| US6565532B1 (en) * | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
| US6537242B1 (en) * | 2000-06-06 | 2003-03-25 | Becton, Dickinson And Company | Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance |
| US6494830B1 (en) | 2000-06-22 | 2002-12-17 | Guidance Interactive Technologies, Inc. | Handheld controller for monitoring/using medical parameters |
| US6603987B2 (en) | 2000-07-11 | 2003-08-05 | Bayer Corporation | Hollow microneedle patch |
| US6440096B1 (en) | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
| US7131987B2 (en) | 2000-10-16 | 2006-11-07 | Corium International, Inc. | Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation |
| US7108681B2 (en) * | 2000-10-16 | 2006-09-19 | Corium International, Inc. | Microstructures for delivering a composition cutaneously to skin |
| US6533884B1 (en) * | 2000-11-03 | 2003-03-18 | Printpack Illinois, Inc. | Method and system for extrusion embossing |
| US6591133B1 (en) * | 2000-11-27 | 2003-07-08 | Microlin Llc | Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices |
| WO2002064193A2 (en) * | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
| AU2002250011A1 (en) * | 2001-02-05 | 2002-08-19 | Becton, Dickinson And Company | Microprotrusion array and methods of making a microprotrusion |
| JP3696513B2 (ja) * | 2001-02-19 | 2005-09-21 | 住友精密工業株式会社 | 針状体の製造方法 |
| US6663820B2 (en) * | 2001-03-14 | 2003-12-16 | The Procter & Gamble Company | Method of manufacturing microneedle structures using soft lithography and photolithography |
| US6591124B2 (en) * | 2001-05-11 | 2003-07-08 | The Procter & Gamble Company | Portable interstitial fluid monitoring system |
| US6767341B2 (en) * | 2001-06-13 | 2004-07-27 | Abbott Laboratories | Microneedles for minimally invasive drug delivery |
| US6881203B2 (en) * | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
| AU2002333636A1 (en) | 2001-09-14 | 2003-04-01 | The Procter And Gamble Company | Microstructures for delivering a composition cutaneously to skin using rotatable structures |
| CA2460673A1 (en) | 2001-09-14 | 2003-03-27 | The Procter & Gamble Company | Method of exfoliation of skin using closely-packed microstructures and apparatus therefor |
-
2001
- 2001-03-14 US US09/808,534 patent/US6663820B2/en not_active Expired - Lifetime
-
2002
- 2002-03-13 EP EP02750607A patent/EP1377338B9/de not_active Expired - Lifetime
- 2002-03-13 ES ES02750607T patent/ES2311615T3/es not_active Expired - Lifetime
- 2002-03-13 WO PCT/US2002/007543 patent/WO2002072189A2/en active Application Filing
- 2002-03-13 AT AT02750607T patent/ATE403465T1/de not_active IP Right Cessation
- 2002-03-13 DE DE60228065T patent/DE60228065D1/de not_active Expired - Lifetime
- 2002-03-13 CA CA002436207A patent/CA2436207C/en not_active Expired - Lifetime
- 2002-03-13 JP JP2002571146A patent/JP4778669B2/ja not_active Expired - Lifetime
-
2003
- 2003-12-03 US US10/727,124 patent/US7763203B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2311615T3 (es) | 2009-02-16 |
| US20020133129A1 (en) | 2002-09-19 |
| US7763203B2 (en) | 2010-07-27 |
| WO2002072189A2 (en) | 2002-09-19 |
| WO2002072189A3 (en) | 2003-03-20 |
| JP2004526581A (ja) | 2004-09-02 |
| EP1377338B9 (de) | 2008-11-05 |
| ATE403465T1 (de) | 2008-08-15 |
| EP1377338A2 (de) | 2004-01-07 |
| EP1377338B1 (de) | 2008-08-06 |
| US6663820B2 (en) | 2003-12-16 |
| CA2436207A1 (en) | 2002-09-19 |
| US20040146611A1 (en) | 2004-07-29 |
| CA2436207C (en) | 2008-12-02 |
| JP4778669B2 (ja) | 2011-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60228065D1 (de) | Verfahren zur herstellung von mikronadelstrukturen mit sanfter lithographie und photolithographie | |
| Wang et al. | Fabrication of well-defined mushroom-shaped structures for biomimetic dry adhesive by conventional photolithography and molding | |
| Yi et al. | Simple and reliable fabrication of bioinspired mushroom-shaped micropillars with precisely controlled tip geometries | |
| JP4192174B2 (ja) | ソフトモールドの製造方法 | |
| ATE343544T1 (de) | Membran für mikroelektromekanischen schalter und verfahren zu dessen herstellung und verwendung | |
| CA2449193A1 (en) | Method of manufacturing a microfluidic structure, in particular a biochip, and structure obtained by said method | |
| WO2002064193A3 (en) | Microneedle devices and production thereof | |
| KR101565835B1 (ko) | 복제 몰드 제조 방법 및 이를 이용한 미세 구조 및 그 활용. | |
| CN104039951B (zh) | 用于引导细胞迁移的装置和实施这种装置的引导方法 | |
| US20140329061A1 (en) | Durable Hydrophilic Dry Adhesives with Hierarchical Structure and Method of Making | |
| Gallego-Perez et al. | Versatile methods for the fabrication of polyvinylidene fluoride microstructures | |
| Zhao et al. | High-definition micropatterning method for hard, stiff and brittle polymers | |
| Li et al. | Application and development of shape memory micro/nano patterns | |
| Alameda et al. | Multilevel hierarchical topographies by combined photolithography and nanoimprinting processes to create surfaces with controlled wetting | |
| KR101863817B1 (ko) | 건식접착 구조물의 제조방법 | |
| Yu et al. | Micropatterning of polymer substrates for cell culture | |
| JP2008125864A (ja) | 針状体の製造方法 | |
| US20130174973A1 (en) | Microfluidic devices and methods of manufacturing | |
| ATE344844T1 (de) | Verfahren zur herstellung von formkörpern mit thermoregulativen eigenschaften | |
| TWI322331B (de) | ||
| WO2003086958A3 (de) | Verfahren zur herstellung eines erzeugnisses mit einer strukturierten oberfläche | |
| Park et al. | High-aspect-ratio tapered structures using an integrated lens technique | |
| JPWO2007049494A1 (ja) | パターニングされた物質の製造方法 | |
| KR101138472B1 (ko) | 바이오 칩의 미세환경 내에서 세포를 공배양하는 방법 | |
| KR102159231B1 (ko) | 세포 배양용 용기 및 이의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |