DE60227507D1 - Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit - Google Patents

Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit

Info

Publication number
DE60227507D1
DE60227507D1 DE60227507T DE60227507T DE60227507D1 DE 60227507 D1 DE60227507 D1 DE 60227507D1 DE 60227507 T DE60227507 T DE 60227507T DE 60227507 T DE60227507 T DE 60227507T DE 60227507 D1 DE60227507 D1 DE 60227507D1
Authority
DE
Germany
Prior art keywords
treatment
dosed
low
alzheimer disease
lhrh antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60227507T
Other languages
English (en)
Inventor
Juergen Engel
Rainer Voegeli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeterna Zentaris GmbH
Original Assignee
Aeterna Zentaris GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris GmbH filed Critical Aeterna Zentaris GmbH
Application granted granted Critical
Publication of DE60227507D1 publication Critical patent/DE60227507D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE60227507T 2001-04-30 2002-04-27 Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit Expired - Fee Related DE60227507D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28743401P 2001-04-30 2001-04-30
PCT/EP2002/004677 WO2002102401A1 (en) 2001-04-30 2002-04-27 Treatment of dementia and neurodegenerative diseases with intermediate doses of lhrh antagonists

Publications (1)

Publication Number Publication Date
DE60227507D1 true DE60227507D1 (de) 2008-08-21

Family

ID=23102886

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60227507T Expired - Fee Related DE60227507D1 (de) 2001-04-30 2002-04-27 Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit

Country Status (28)

Country Link
US (1) US7288517B2 (de)
EP (1) EP1392348B1 (de)
JP (1) JP2004529207A (de)
KR (1) KR20040000446A (de)
CN (1) CN1317030C (de)
AT (1) ATE400287T1 (de)
AU (1) AU2002310788B2 (de)
BG (1) BG108339A (de)
BR (1) BR0209290A (de)
CA (1) CA2444876A1 (de)
CZ (1) CZ20033167A3 (de)
DE (1) DE60227507D1 (de)
DK (1) DK1392348T3 (de)
ES (1) ES2307760T3 (de)
HK (1) HK1072000A1 (de)
HU (1) HUP0400067A2 (de)
IL (1) IL156777A0 (de)
MX (1) MXPA03008666A (de)
NO (1) NO20034322D0 (de)
NZ (1) NZ544417A (de)
PL (1) PL362319A1 (de)
PT (1) PT1392348E (de)
RU (1) RU2319501C2 (de)
SI (1) SI1392348T1 (de)
SK (1) SK14512003A3 (de)
UA (1) UA80679C2 (de)
WO (1) WO2002102401A1 (de)
ZA (1) ZA200305326B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US20020077327A1 (en) * 1999-09-23 2002-06-20 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
CN1186326C (zh) 2000-07-05 2005-01-26 山之内制药株式会社 丙－1,3－二酮衍生物
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
MXPA06014131A (es) 2004-06-04 2007-03-07 Astellas Pharma Inc Derivado de propano-1,3-diona o su sal.
US20080171736A1 (en) * 2004-12-23 2008-07-17 Gregory Christopher W Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists
EP1827468B1 (de) * 2004-12-23 2012-08-22 Curaxis Pharmaceutical Corporation Acetylcholinesterasehemmer und Leuprolidacetat zur Behandlung von Alzheimer-Krankheit
AU2006232469B2 (en) * 2005-03-31 2011-03-31 Astellas Pharma Inc. Propane-1,3-dion derivative or salt thereof
RU2009119181A (ru) * 2006-10-21 2010-11-27 Эбботт Гмбх Унд Ко.Кг (De) Гетероциклические соединения и их применение в качестве ингибиторов гликогенсинтаза-киназы-3
JP2010538994A (ja) * 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 例えば肺炎連鎖球菌感染症を治療するためのｂｆｇｆ１−２４および任意での（ａｒｇ８）バソプレシンの使用
WO2009033765A2 (en) * 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2095818A1 (de) * 2008-02-29 2009-09-02 AEterna Zentaris GmbH Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen
US20110129532A1 (en) * 2008-05-29 2011-06-02 Isr Immune System Regulation Ab Method and means for treating viral disease, in particular hiv/aids
US9266855B2 (en) 2010-09-27 2016-02-23 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
US9090592B2 (en) 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
EP3560555A1 (de) * 2018-04-26 2019-10-30 LifeArc Zusammensetzung zur behandlung einer oder mehrerer östrogenvermittelter krankheiten

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135743A (en) 1960-06-29 1964-06-02 Sterling Drug Inc Steroido[2. 3-d]isoxazoles and preparation thereof
US6150352A (en) * 1996-05-20 2000-11-21 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
DE19911771B4 (de) 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
CA2372044A1 (en) * 1999-05-14 2000-11-23 Neurocrine Biosciences, Inc. Imidazo- and pyrrolo[1,2-a]pyrimid-4-ones as gonadotropin-releasing hormone receptor antagonists
CA2309395A1 (en) 1999-06-04 2000-12-04 Richard Lloyd Bowen Methods for preventing and treating alzheimer's disease
MXPA02003614A (es) * 1999-10-15 2002-10-23 Neurocrine Biosciences Inc Antagonistas del receptor de la hormona liberadora de ganadotropina y metodos relacionados con los mismos..
WO2001078780A1 (fr) 2000-04-13 2001-10-25 Takeda Chemical Industries, Ltd. Agents preventifs/remedes pour la maladie d'alzheimer
CN1186326C (zh) 2000-07-05 2005-01-26 山之内制药株式会社 丙－1,3－二酮衍生物

Also Published As

Publication number Publication date
HK1072000A1 (en) 2005-08-12
EP1392348B1 (de) 2008-07-09
ATE400287T1 (de) 2008-07-15
AU2002310788B2 (en) 2007-04-05
PT1392348E (pt) 2008-09-09
NO20034322L (no) 2003-09-26
RU2003134949A (ru) 2005-02-10
NZ544417A (en) 2008-03-28
CZ20033167A3 (cs) 2004-08-18
CN1575185A (zh) 2005-02-02
CA2444876A1 (en) 2002-12-27
BG108339A (bg) 2004-11-30
KR20040000446A (ko) 2004-01-03
US20020177556A1 (en) 2002-11-28
ES2307760T3 (es) 2008-12-01
SI1392348T1 (sl) 2008-12-31
CN1317030C (zh) 2007-05-23
WO2002102401A1 (en) 2002-12-27
UA80679C2 (en) 2007-10-25
JP2004529207A (ja) 2004-09-24
BR0209290A (pt) 2004-07-13
SK14512003A3 (sk) 2004-08-03
NO20034322D0 (no) 2003-09-26
ZA200305326B (en) 2003-07-30
MXPA03008666A (es) 2004-10-15
HUP0400067A2 (hu) 2004-04-28
RU2319501C2 (ru) 2008-03-20
PL362319A1 (en) 2004-10-18
US7288517B2 (en) 2007-10-30
DK1392348T3 (da) 2008-09-29
EP1392348A1 (de) 2004-03-03
IL156777A0 (en) 2004-02-08

Similar Documents

Publication Publication Date Title
HK1072000A1 (en) Treatment of alzheimer's diseases with intemediatedoses of lhrh antagonists
EA200201247A1 (ru) Соединения для лечения болезни альцгеймера
ATE409176T1 (de) 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen
WO2002002518A3 (en) Compounds to treat alzheimer's disease
WO2002002520A3 (en) Compounds to treat alzheimer's disease
AT500379B8 (de) Tau-proteine
DE602004021797D1 (de) Behandlung von alzheimer-krankheit und amyloider gehirnangiopathie
HUP0303656A2 (hu) Bruton-féle tirozin kináz modulátorai és Bruton-féle tirozin kináz intermedierek, és eljárások azonosításukra és alkalmazásuk oszteoporózis és rokon betegségek kezelésére és prevenciójára
EA200800880A1 (ru) Комбинация росиглитазона и донепезила, предназначенная для улучшения когнитивной функции
DE60033649D1 (de) Verbindungen und therapeutische methoden
ATE438405T1 (de) Verwendung von peptidantagonisten des zonulin zur behandlung von diabetes
ATE319439T1 (de) Mittel zur behandlung von erkrankungen des tracheo-bronchialtraktes, insbesondere der copd
DK1007040T3 (da) Anvendelsen af phanquinon til behandlingen af Alzheimers sygdom
DE59900222D1 (de) Verwendung von hyperforin und hyperforinhaltigen extrakten zur behandlung und prophylaxe von demenzerkrankungen
DE50010648D1 (de) Triazinonverbindungen zur behandlung von durch den befall mit parasitischen protozoen bedingten krankheiten
MXPA03008406A (es) Nuevas composiciones de medicamentos sobre la base de agentes anticolinergicos y agentes antagonistas de endotelina.
EA200200987A1 (ru) Лечение заболеваний, связанных с серотонинергической системой
ATE337790T1 (de) Verwendung von cortisol-sequestriermitteln zur behandlung von hypercortisolaemie-verwandten erkrankungen
DE60143025D1 (de) Zusammensetzung zur behandlung von periodontalen erkrankungen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee