DE60227507D1 - Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit - Google Patents
Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheitInfo
- Publication number
- DE60227507D1 DE60227507D1 DE60227507T DE60227507T DE60227507D1 DE 60227507 D1 DE60227507 D1 DE 60227507D1 DE 60227507 T DE60227507 T DE 60227507T DE 60227507 T DE60227507 T DE 60227507T DE 60227507 D1 DE60227507 D1 DE 60227507D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- dosed
- low
- alzheimer disease
- lhrh antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28743401P | 2001-04-30 | 2001-04-30 | |
PCT/EP2002/004677 WO2002102401A1 (en) | 2001-04-30 | 2002-04-27 | Treatment of dementia and neurodegenerative diseases with intermediate doses of lhrh antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60227507D1 true DE60227507D1 (de) | 2008-08-21 |
Family
ID=23102886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60227507T Expired - Fee Related DE60227507D1 (de) | 2001-04-30 | 2002-04-27 | Niedrigdosierte lhrh antagonisten zur behandlung von neurodegenerativen krankheiten, insbesondere alzheimer krankheit |
Country Status (28)
Country | Link |
---|---|
US (1) | US7288517B2 (de) |
EP (1) | EP1392348B1 (de) |
JP (1) | JP2004529207A (de) |
KR (1) | KR20040000446A (de) |
CN (1) | CN1317030C (de) |
AT (1) | ATE400287T1 (de) |
AU (1) | AU2002310788B2 (de) |
BG (1) | BG108339A (de) |
BR (1) | BR0209290A (de) |
CA (1) | CA2444876A1 (de) |
CZ (1) | CZ20033167A3 (de) |
DE (1) | DE60227507D1 (de) |
DK (1) | DK1392348T3 (de) |
ES (1) | ES2307760T3 (de) |
HK (1) | HK1072000A1 (de) |
HU (1) | HUP0400067A2 (de) |
IL (1) | IL156777A0 (de) |
MX (1) | MXPA03008666A (de) |
NO (1) | NO20034322D0 (de) |
NZ (1) | NZ544417A (de) |
PL (1) | PL362319A1 (de) |
PT (1) | PT1392348E (de) |
RU (1) | RU2319501C2 (de) |
SI (1) | SI1392348T1 (de) |
SK (1) | SK14512003A3 (de) |
UA (1) | UA80679C2 (de) |
WO (1) | WO2002102401A1 (de) |
ZA (1) | ZA200305326B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
US20020077327A1 (en) * | 1999-09-23 | 2002-06-20 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
CN1186326C (zh) | 2000-07-05 | 2005-01-26 | 山之内制药株式会社 | 丙-1,3-二酮衍生物 |
DE10137174A1 (de) * | 2001-07-31 | 2003-02-13 | Zentaris Ag | Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität |
MXPA06014131A (es) | 2004-06-04 | 2007-03-07 | Astellas Pharma Inc | Derivado de propano-1,3-diona o su sal. |
US20080171736A1 (en) * | 2004-12-23 | 2008-07-17 | Gregory Christopher W | Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists |
EP1827468B1 (de) * | 2004-12-23 | 2012-08-22 | Curaxis Pharmaceutical Corporation | Acetylcholinesterasehemmer und Leuprolidacetat zur Behandlung von Alzheimer-Krankheit |
AU2006232469B2 (en) * | 2005-03-31 | 2011-03-31 | Astellas Pharma Inc. | Propane-1,3-dion derivative or salt thereof |
RU2009119181A (ru) * | 2006-10-21 | 2010-11-27 | Эбботт Гмбх Унд Ко.Кг (De) | Гетероциклические соединения и их применение в качестве ингибиторов гликогенсинтаза-киназы-3 |
JP2010538994A (ja) * | 2007-09-11 | 2010-12-16 | モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト | 例えば肺炎連鎖球菌感染症を治療するためのbfgf1−24および任意での(arg8)バソプレシンの使用 |
WO2009033765A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
EP2095818A1 (de) * | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen |
US20110129532A1 (en) * | 2008-05-29 | 2011-06-02 | Isr Immune System Regulation Ab | Method and means for treating viral disease, in particular hiv/aids |
US9266855B2 (en) | 2010-09-27 | 2016-02-23 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
US9090592B2 (en) | 2010-12-30 | 2015-07-28 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
EP3560555A1 (de) * | 2018-04-26 | 2019-10-30 | LifeArc | Zusammensetzung zur behandlung einer oder mehrerer östrogenvermittelter krankheiten |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3135743A (en) | 1960-06-29 | 1964-06-02 | Sterling Drug Inc | Steroido[2. 3-d]isoxazoles and preparation thereof |
US6150352A (en) * | 1996-05-20 | 2000-11-21 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
DE19911771B4 (de) | 1999-03-17 | 2006-03-30 | Zentaris Gmbh | LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung |
CA2372044A1 (en) * | 1999-05-14 | 2000-11-23 | Neurocrine Biosciences, Inc. | Imidazo- and pyrrolo[1,2-a]pyrimid-4-ones as gonadotropin-releasing hormone receptor antagonists |
CA2309395A1 (en) | 1999-06-04 | 2000-12-04 | Richard Lloyd Bowen | Methods for preventing and treating alzheimer's disease |
MXPA02003614A (es) * | 1999-10-15 | 2002-10-23 | Neurocrine Biosciences Inc | Antagonistas del receptor de la hormona liberadora de ganadotropina y metodos relacionados con los mismos.. |
WO2001078780A1 (fr) | 2000-04-13 | 2001-10-25 | Takeda Chemical Industries, Ltd. | Agents preventifs/remedes pour la maladie d'alzheimer |
CN1186326C (zh) | 2000-07-05 | 2005-01-26 | 山之内制药株式会社 | 丙-1,3-二酮衍生物 |
-
2002
- 2002-04-27 AU AU2002310788A patent/AU2002310788B2/en not_active Ceased
- 2002-04-27 CA CA002444876A patent/CA2444876A1/en not_active Abandoned
- 2002-04-27 EP EP02735312A patent/EP1392348B1/de not_active Expired - Lifetime
- 2002-04-27 PT PT02735312T patent/PT1392348E/pt unknown
- 2002-04-27 CZ CZ20033167A patent/CZ20033167A3/cs unknown
- 2002-04-27 SK SK1451-2003A patent/SK14512003A3/sk unknown
- 2002-04-27 SI SI200230730T patent/SI1392348T1/sl unknown
- 2002-04-27 IL IL15677702A patent/IL156777A0/xx unknown
- 2002-04-27 BR BR0209290-5A patent/BR0209290A/pt not_active IP Right Cessation
- 2002-04-27 MX MXPA03008666A patent/MXPA03008666A/es active IP Right Grant
- 2002-04-27 KR KR10-2003-7014128A patent/KR20040000446A/ko not_active Application Discontinuation
- 2002-04-27 RU RU2003134949/14A patent/RU2319501C2/ru not_active IP Right Cessation
- 2002-04-27 CN CNB028042964A patent/CN1317030C/zh not_active Expired - Fee Related
- 2002-04-27 AT AT02735312T patent/ATE400287T1/de not_active IP Right Cessation
- 2002-04-27 DE DE60227507T patent/DE60227507D1/de not_active Expired - Fee Related
- 2002-04-27 ES ES02735312T patent/ES2307760T3/es not_active Expired - Lifetime
- 2002-04-27 HU HU0400067A patent/HUP0400067A2/hu unknown
- 2002-04-27 JP JP2003504987A patent/JP2004529207A/ja not_active Withdrawn
- 2002-04-27 US US10/133,967 patent/US7288517B2/en not_active Expired - Fee Related
- 2002-04-27 UA UA2003109180A patent/UA80679C2/uk unknown
- 2002-04-27 WO PCT/EP2002/004677 patent/WO2002102401A1/en active IP Right Grant
- 2002-04-27 NZ NZ544417A patent/NZ544417A/en unknown
- 2002-04-27 DK DK02735312T patent/DK1392348T3/da active
- 2002-04-27 PL PL36231902A patent/PL362319A1/xx not_active Application Discontinuation
-
2003
- 2003-07-10 ZA ZA200305326A patent/ZA200305326B/xx unknown
- 2003-09-26 NO NO20034322A patent/NO20034322D0/no not_active Application Discontinuation
- 2003-11-10 BG BG108339A patent/BG108339A/bg unknown
-
2005
- 2005-06-08 HK HK05104803A patent/HK1072000A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1072000A1 (en) | 2005-08-12 |
EP1392348B1 (de) | 2008-07-09 |
ATE400287T1 (de) | 2008-07-15 |
AU2002310788B2 (en) | 2007-04-05 |
PT1392348E (pt) | 2008-09-09 |
NO20034322L (no) | 2003-09-26 |
RU2003134949A (ru) | 2005-02-10 |
NZ544417A (en) | 2008-03-28 |
CZ20033167A3 (cs) | 2004-08-18 |
CN1575185A (zh) | 2005-02-02 |
CA2444876A1 (en) | 2002-12-27 |
BG108339A (bg) | 2004-11-30 |
KR20040000446A (ko) | 2004-01-03 |
US20020177556A1 (en) | 2002-11-28 |
ES2307760T3 (es) | 2008-12-01 |
SI1392348T1 (sl) | 2008-12-31 |
CN1317030C (zh) | 2007-05-23 |
WO2002102401A1 (en) | 2002-12-27 |
UA80679C2 (en) | 2007-10-25 |
JP2004529207A (ja) | 2004-09-24 |
BR0209290A (pt) | 2004-07-13 |
SK14512003A3 (sk) | 2004-08-03 |
NO20034322D0 (no) | 2003-09-26 |
ZA200305326B (en) | 2003-07-30 |
MXPA03008666A (es) | 2004-10-15 |
HUP0400067A2 (hu) | 2004-04-28 |
RU2319501C2 (ru) | 2008-03-20 |
PL362319A1 (en) | 2004-10-18 |
US7288517B2 (en) | 2007-10-30 |
DK1392348T3 (da) | 2008-09-29 |
EP1392348A1 (de) | 2004-03-03 |
IL156777A0 (en) | 2004-02-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |