DE60227014D1 - Mikronadeln für minimal-invasive Medikamentenverabreichung oder für diagnostisches Probenehmen - Google Patents

Mikronadeln für minimal-invasive Medikamentenverabreichung oder für diagnostisches Probenehmen

Info

Publication number
DE60227014D1
DE60227014D1 DE60227014T DE60227014T DE60227014D1 DE 60227014 D1 DE60227014 D1 DE 60227014D1 DE 60227014 T DE60227014 T DE 60227014T DE 60227014 T DE60227014 T DE 60227014T DE 60227014 D1 DE60227014 D1 DE 60227014D1
Authority
DE
Germany
Prior art keywords
processor
electrically coupled
fluid
medicinal fluid
disposable cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60227014T
Other languages
English (en)
Inventor
Steve T Cho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospira Inc
Original Assignee
Hospira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospira Inc filed Critical Hospira Inc
Application granted granted Critical
Publication of DE60227014D1 publication Critical patent/DE60227014D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81CPROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00111Tips, pillars, i.e. raised structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221Valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150748Having means for aiding positioning of the piercing device at a location where the body is to be pierced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150847Communication to or from blood sampling device
    • A61B5/15087Communication to or from blood sampling device short range, e.g. between console and disposable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150969Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150977Arrays of piercing elements for simultaneous piercing
    • A61B5/150984Microneedles or microblades
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/157Devices characterised by integrated means for measuring characteristics of blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/05Microfluidics
    • B81B2201/055Microneedles
DE60227014T 2001-06-13 2002-05-22 Mikronadeln für minimal-invasive Medikamentenverabreichung oder für diagnostisches Probenehmen Expired - Fee Related DE60227014D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/880,377 US6767341B2 (en) 2001-06-13 2001-06-13 Microneedles for minimally invasive drug delivery

Publications (1)

Publication Number Publication Date
DE60227014D1 true DE60227014D1 (de) 2008-07-17

Family

ID=25376125

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60227014T Expired - Fee Related DE60227014D1 (de) 2001-06-13 2002-05-22 Mikronadeln für minimal-invasive Medikamentenverabreichung oder für diagnostisches Probenehmen
DE60217510T Expired - Fee Related DE60217510T2 (de) 2001-06-13 2002-05-22 Mikronadeln für die minimal invasive arzneimittelabgabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60217510T Expired - Fee Related DE60217510T2 (de) 2001-06-13 2002-05-22 Mikronadeln für die minimal invasive arzneimittelabgabe

Country Status (9)

Country Link
US (2) US6767341B2 (de)
EP (2) EP1418977B1 (de)
JP (1) JP4286131B2 (de)
AT (1) ATE397473T1 (de)
AU (1) AU2002312013A1 (de)
CA (1) CA2450367C (de)
DE (2) DE60227014D1 (de)
ES (2) ES2308657T3 (de)
WO (1) WO2002100474A2 (de)

Families Citing this family (222)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL134997A0 (en) * 2000-03-09 2001-05-20 Yehoshua Yeshurun Health care system based on micro device
US6533949B1 (en) * 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
HUP0303558A2 (en) * 2000-10-13 2004-01-28 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6749792B2 (en) * 2001-07-09 2004-06-15 Lifescan, Inc. Micro-needles and methods of manufacture and use thereof
SE0102736D0 (sv) * 2001-08-14 2001-08-14 Patrick Griss Side opened out-of-plane microneedles for microfluidic transdermal interfacing and fabrication process of side opened out-of-plane microneedles
US20030044318A1 (en) * 2001-09-05 2003-03-06 Lorin Olson Devices for analyte concentration determination and methods of using the same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
DE10238266A1 (de) * 2002-02-28 2003-11-06 Ibidi Gmbh Mikrofluidsystem
WO2004033021A1 (en) * 2002-10-07 2004-04-22 Biovalve Technologies, Inc. Microneedle array patch
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US7415299B2 (en) * 2003-04-18 2008-08-19 The Regents Of The University Of California Monitoring method and/or apparatus
AU2004244909A1 (en) * 2003-06-10 2004-12-16 Medrx Co., Ltd. Process for producing pad base for transdermal drug administration, pad base for transdermal drug administration and needle
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20050228313A1 (en) * 2003-12-04 2005-10-13 University Technologies International Inc. Fluid sampling, analysis and delivery system
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US7850676B2 (en) * 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US20070292445A1 (en) * 2004-07-06 2007-12-20 Transpharma Medical Ltd. Delivery system for transdermal immunization
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US7076987B2 (en) 2004-08-05 2006-07-18 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US7560036B2 (en) * 2004-08-05 2009-07-14 Apogee Technology, Inc. System and method for drug delivery and microfluidic applications using microneedles
US7086266B2 (en) 2004-08-05 2006-08-08 Becton, Dickinson And Company Method of producing tapered or pointed cannula
ATE490037T1 (de) 2004-08-16 2010-12-15 Functional Microstructures Ltd Verfahren zur herstellung einer mikronadel oder eines mikroimplantats
SE0402100D0 (sv) * 2004-08-30 2004-08-30 Bonsens Ab Molded micro-needles
US7132054B1 (en) * 2004-09-08 2006-11-07 Sandia Corporation Method to fabricate hollow microneedle arrays
EP1819379B1 (de) * 2004-11-18 2016-08-31 Nanopass Technologies Ltd. System zur abgabe einer flüssigkeit in eine flexible biologische barriere
US20080009800A1 (en) * 2004-12-02 2008-01-10 Nickel Janice H Transdermal drug delivery device
EP1671585A1 (de) * 2004-12-17 2006-06-21 F. Hoffmann-La Roche Ag Verfahren zur Herstellung eines Stechelements
US7588705B2 (en) 2004-12-28 2009-09-15 Nabtesco Corporation Skin needle manufacturing apparatus and skin needle manufacturing method
AU2006209421A1 (en) * 2005-01-31 2006-08-03 Bioserentach Co., Ltd. Transdermal absorption preparation, sheet holding transdermal absorption preparation and transdermal absorption preparation holder
JP4731931B2 (ja) 2005-02-03 2011-07-27 Tti・エルビュー株式会社 イオントフォレーシス装置
TW200640519A (en) * 2005-02-16 2006-12-01 Alza Corp Microprojection arrays with improved biocompatibility
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Tti・エルビュー株式会社 イオントフォレーシス装置
CA2602259A1 (en) 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US20060264783A1 (en) * 2005-05-09 2006-11-23 Holmes Elizabeth A Systems and methods for monitoring pharmacological parameters
US8505544B2 (en) * 2005-05-31 2013-08-13 The Board Of Trustees Of The Leland Stanford Junior University Optically-implemented microsurgery system and approach
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
JPWO2007032446A1 (ja) 2005-09-15 2009-03-19 Tti・エルビュー株式会社 ロッド型イオントフォレーシス装置
US20070073212A1 (en) * 2005-09-28 2007-03-29 Takehiko Matsumura Iontophoresis apparatus and method to deliver active agents to biological interfaces
JP2009509685A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 損傷組織の治癒を増強するための血管新生因子の送達のためのイオントフォレーシス装置及び方法
US7574256B2 (en) * 2005-09-30 2009-08-11 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
US7848801B2 (en) 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US7699819B2 (en) * 2006-02-21 2010-04-20 The Hong Kong University Of Science And Technology Molecular sieve and zeolite microneedles and preparation thereof
US7415858B2 (en) 2006-02-21 2008-08-26 Tyco Healthcare Group Lp Grindless surgical needle manufacture
US8858807B2 (en) * 2006-03-24 2014-10-14 3M Innovative Properties Company Process for making microneedles, microneedle arrays, masters, and replication tools
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US20090131778A1 (en) * 2006-03-28 2009-05-21 Jina Arvind N Devices, systems, methods and tools for continuous glucose monitoring
US20080154107A1 (en) * 2006-12-20 2008-06-26 Jina Arvind N Device, systems, methods and tools for continuous glucose monitoring
US20100049021A1 (en) * 2006-03-28 2010-02-25 Jina Arvind N Devices, systems, methods and tools for continuous analyte monitoring
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
US20080008745A1 (en) * 2006-06-21 2008-01-10 University Of Kentucky Research Foundation Transdermal delivery of naltrexone hydrochloride, naltrexol hydrochloride, and bis(hydroxy-methyl)propionyl-3-0 ester naltrexone using microneedles
DE102006028781A1 (de) * 2006-06-23 2007-12-27 Robert Bosch Gmbh Verfahren zur Herstellung von porösen Mikronadeln und ihre Verwendung
JP4265696B2 (ja) * 2006-07-04 2009-05-20 凸版印刷株式会社 マイクロニードルの製造方法
JP5338021B2 (ja) * 2006-07-04 2013-11-13 凸版印刷株式会社 針状体の製造方法
CN101528830A (zh) 2006-07-10 2009-09-09 麦德医像公司 超弹性环氧水凝胶
US8250729B2 (en) * 2006-07-12 2012-08-28 University Of Utah Research Foundation 3D fabrication of needle tip geometry and knife blade
KR100781702B1 (ko) * 2006-07-21 2007-12-03 연세대학교 산학협력단 중공형 마이크로니들 및 이의 제조방법
JP4396776B2 (ja) 2006-07-27 2010-01-13 凸版印刷株式会社 マイクロニードルの製造方法
EP2062611A4 (de) * 2006-08-18 2010-01-06 Toppan Printing Co Ltd Mikronadel und mikronadelstelle
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
US20080097352A1 (en) * 2006-09-12 2008-04-24 Beck Patricia A Methods of fabricating microneedles with bio-sensory functionality
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
WO2008042902A2 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
JPWO2008062832A1 (ja) 2006-11-22 2010-03-04 凸版印刷株式会社 マイクロニードルアレイ及びマイクロニードルアレイの製造方法
JP5383497B2 (ja) 2006-12-01 2014-01-08 Tti・エルビュー株式会社 装置、例として経皮送達装置に給電し且つ/又は当該装置を制御するシステム及び装置
WO2008091602A2 (en) 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
US20090011158A1 (en) * 2007-03-18 2009-01-08 Nanopass Technologies Ltd. Microneedle structures and corresponding production methods employing a backside wet etch
US20080234562A1 (en) * 2007-03-19 2008-09-25 Jina Arvind N Continuous analyte monitor with multi-point self-calibration
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
US20100224590A1 (en) * 2007-05-20 2010-09-09 Nanopass Technologies Ltd. Method for producing microneedle structures employing one-sided processing
US20080312518A1 (en) * 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
WO2009029572A1 (en) * 2007-08-24 2009-03-05 Deka Products Limited Partnership Microneedle systems and apparatus
JP5173332B2 (ja) * 2007-09-10 2013-04-03 凸版印刷株式会社 マイクロニードルおよびマイクロニードル製造方法
JP5223278B2 (ja) * 2007-09-27 2013-06-26 凸版印刷株式会社 マイクロニードル製造方法
CN101808588B (zh) * 2007-09-28 2012-12-19 贝尔法斯特女王大学 递送装置及方法
US9345836B2 (en) 2007-10-02 2016-05-24 Medimop Medical Projects Ltd. Disengagement resistant telescoping assembly and unidirectional method of assembly for such
US9656019B2 (en) 2007-10-02 2017-05-23 Medimop Medical Projects Ltd. Apparatuses for securing components of a drug delivery system during transport and methods of using same
US10420880B2 (en) 2007-10-02 2019-09-24 West Pharma. Services IL, Ltd. Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
US7967795B1 (en) 2010-01-19 2011-06-28 Lamodel Ltd. Cartridge interface assembly with driving plunger
CN101868273B (zh) 2007-10-02 2014-10-15 莱蒙德尔有限公司 外部药泵
JP5466161B2 (ja) * 2007-10-09 2014-04-09 トランスファーマ メディカル リミテッド 磁気的なパッチ連結物
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
MY157968A (en) * 2007-11-14 2016-08-30 Mimos Berhad Method for fabricating microneedled and microneedle fabricated from the same
WO2009073734A2 (en) 2007-12-03 2009-06-11 Medipacs, Inc. Fluid metering device
MX2010006062A (es) 2007-12-05 2010-09-14 Syneron Medical Ltd Aplicador desechable de energia electromagnetica y metodo para su uso.
JP5461427B2 (ja) 2007-12-17 2014-04-02 ニューワールド ファーマシューティカルズ,エルエルシー 統合的な皮内送達、診断、及び、情報伝達システム
WO2009079712A1 (en) 2007-12-24 2009-07-02 The University Of Queensland Coating method
KR101626167B1 (ko) 2008-01-17 2016-05-31 시네론 메디컬 리미티드 개인용 모발 제거 장치 및 그 사용 방법
JP2011509791A (ja) 2008-01-24 2011-03-31 シネロン メディカル リミテッド 脂肪組織治療の機器、装置および方法
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
WO2009097660A1 (en) 2008-02-07 2009-08-13 The University Of Queensland Patch production
WO2009105709A1 (en) 2008-02-21 2009-08-27 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US20090234322A1 (en) * 2008-03-12 2009-09-17 Ultradent Products, Inc. Method of dental tissue injection using an array of micro-needles
FR2929135A1 (fr) * 2008-03-31 2009-10-02 Commissariat Energie Atomique Dispositif d'aliquotage et de dispense d'un liquide
KR101383285B1 (ko) 2008-05-21 2014-04-08 테라젝트, 인코포레이티드 고용체 퍼포레이터 패치의 제조 방법 및 그 사용
AU2009250341A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection using a needle projection patch
US20110150946A1 (en) * 2008-08-22 2011-06-23 Al-Ghananeem Abeer M Transdermal Delivery of Apomorphine Using Microneedles
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
EP2334234A4 (de) 2008-09-19 2013-03-20 Tandem Diabetes Care Inc Vorrichtung zur messung der konzentration eines gelösten stoffs und entsprechende verfahren
KR101523807B1 (ko) 2008-09-21 2015-05-28 시네론 메디컬 리미티드 개인용 피부 치료 장치
US20100145305A1 (en) * 2008-11-10 2010-06-10 Ruth Alon Low volume accurate injector
US8734697B2 (en) 2008-12-22 2014-05-27 The University Of Queensland Patch production
US8152779B2 (en) * 2008-12-30 2012-04-10 Medimop Medical Projects Ltd. Needle assembly for drug pump
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US20110306878A1 (en) 2009-02-26 2011-12-15 Liquidia Technologies, Inc. Interventional drug delivery system and associated methods
CN101829396B (zh) * 2009-03-27 2013-01-30 清华大学 微针阵列芯片及利用其的经皮给药贴剂及其制备方法
KR100922138B1 (ko) * 2009-04-14 2009-10-19 봄텍전자 주식회사 피부용 액체침투장치
ES2464495T3 (es) * 2009-07-30 2014-06-03 3M Innovative Properties Company Tobera y método para hacer la misma
WO2011014704A2 (en) 2009-07-30 2011-02-03 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
US8409147B2 (en) 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
WO2011032011A1 (en) 2009-09-10 2011-03-17 Medipacs, Inc. Low profile actuator and improved method of caregiver controlled administration of therapeutics
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
US10071196B2 (en) 2012-05-15 2018-09-11 West Pharma. Services IL, Ltd. Method for selectively powering a battery-operated drug-delivery device and device therefor
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス, インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
US9500186B2 (en) 2010-02-01 2016-11-22 Medipacs, Inc. High surface area polymer actuator with gas mitigating components
RU2585138C2 (ru) 2010-04-28 2016-05-27 Кимберли-Кларк Ворлдвайд, Инк. Медицинские устройства для доставки кирнк
EP2563450B1 (de) 2010-04-28 2017-07-26 Kimberly-Clark Worldwide, Inc. Vorrichtung zur verabreichung eines medikaments gegen rheumatoide arthritis
MX2012012567A (es) 2010-04-28 2012-11-21 Kimberly Clark Co Metodo para aumentar la permeabilidad de una barrera epitelial.
JP5871907B2 (ja) 2010-04-28 2016-03-01 キンバリー クラーク ワールドワイド インコーポレイテッド 細胞間相互作用を強化させたナノパターンド医療デバイス
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
WO2011141907A1 (en) 2010-05-10 2011-11-17 Medimop Medical Projects Ltd. Low volume accurate injector
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
TWI455722B (zh) 2010-06-04 2014-10-11 Pfizer Vaccines Llc 用於預防或治療菸鹼成癮之共軛體
KR101180032B1 (ko) * 2010-07-12 2012-09-05 인싸이토(주) 외형 조절이 가능한 중공형 마이크로니들의 제조방법
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
IT1403293B1 (it) 2010-12-27 2013-10-17 Fond Don Carlo Gnocchi Onlus Apparecchiatura ad aghi per la somministrazione transdermica di farmaci.
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
USD702834S1 (en) 2011-03-22 2014-04-15 Medimop Medical Projects Ltd. Cartridge for use in injection device
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
AU2012323782B2 (en) 2011-10-12 2017-04-06 Vaxxas Pty Limited Delivery device
BR112014009713A2 (pt) 2011-10-27 2017-04-18 Kimberly Clark Co administração transdérmica de agentes bioativos de alta viscosidade
JP6535464B2 (ja) 2011-10-27 2019-06-26 ソレント・セラピューティクス・インコーポレイテッド 生理活性薬剤の送達のための移植可能な装置
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
KR101412535B1 (ko) * 2011-11-29 2014-06-26 연세대학교 산학협력단 유리체강 주사용 중공형 마이크로니들
EP2601928B1 (de) * 2011-12-08 2014-09-17 King Saud University Vorrichtung zur transdermalen Abgabe einer bioaktiven Lösung
DE102011089752A1 (de) * 2011-12-23 2013-06-27 Robert Bosch Gmbh Verfahren zur Herstellung von Silizium-Mikronadelarrays mit Löchern und Mikronadelarray
CN102530848A (zh) * 2012-03-06 2012-07-04 大连理工大学 一种仿蚊子嘴空心微针阵列的制作方法
US9791080B2 (en) 2012-03-12 2017-10-17 Idex Health & Science Llc Microfluidic interconnect
CA2906274A1 (en) 2012-03-14 2013-09-19 Medipacs, Inc. Smart polymer materials with excess reactive molecules
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
ES2743404T3 (es) 2012-12-21 2020-02-19 Corium Inc Matriz para suministro de agente terapéutico y método de fabricación
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
EP2968887B1 (de) 2013-03-12 2022-05-04 Corium, Inc. Mikroprojektionsapplikatoren
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
EP2968118B1 (de) 2013-03-15 2022-02-09 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur verwendung
US9011164B2 (en) 2013-04-30 2015-04-21 Medimop Medical Projects Ltd. Clip contact for easy installation of printed circuit board PCB
US9452281B2 (en) 2013-04-30 2016-09-27 Elwha Llc Tattooing systems and methods
US20150087144A1 (en) * 2013-09-26 2015-03-26 Taiwan Semiconductor Manufacturing Company Ltd. Apparatus and method of manufacturing metal gate semiconductor device
EP3597261A1 (de) * 2014-04-30 2020-01-22 Sorrento Therapeutics, Inc. Drapierte mikronadelanordnung
US10321858B2 (en) * 2014-08-18 2019-06-18 Proteadx, Inc. Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
EP4218892A1 (de) 2015-02-02 2023-08-02 Vaxxas Pty Limited Mikroprojektionsarrayapplikator
US10293120B2 (en) 2015-04-10 2019-05-21 West Pharma. Services IL, Ltd. Redundant injection device status indication
US10149943B2 (en) 2015-05-29 2018-12-11 West Pharma. Services IL, Ltd. Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
EP3302652B1 (de) 2015-06-04 2023-09-06 Medimop Medical Projects Ltd. Kartuscheneinführung für arzneimittelabgavevorrichtung
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
US9987432B2 (en) 2015-09-22 2018-06-05 West Pharma. Services IL, Ltd. Rotation resistant friction adapter for plunger driver of drug delivery device
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
CN108472438B (zh) 2015-10-09 2022-01-28 西医药服务以色列分公司 至预填充的流体储存器的弯曲流体路径附加装置
US10646643B2 (en) 2016-01-21 2020-05-12 West Pharma. Services IL, Ltd. Needle insertion and retraction mechanism
USD801523S1 (en) * 2016-01-21 2017-10-31 Roger Khouri Needle cartridge
JP6513297B2 (ja) 2016-01-21 2019-05-22 ウェスト ファーマ サービシーズ イスラエル リミテッド 自動注射器、受け入れフレーム及び自動注射器におけるカートリッジの接続方法
JP6885960B2 (ja) 2016-01-21 2021-06-16 ウェスト ファーマ サービシーズ イスラエル リミテッド 視覚的インジケータを有する薬剤デリバリデバイス
KR20180131554A (ko) * 2016-03-01 2018-12-10 키토테크 메디컬 인코포레이티드 상처 봉합을 위한 마이크로 구조-기반 시스템, 장치, 및 방법
WO2017161076A1 (en) 2016-03-16 2017-09-21 Medimop Medical Projects Ltd. Staged telescopic screw assembly having different visual indicators
JP6732373B2 (ja) * 2016-03-31 2020-07-29 花王株式会社 微細中空突起具の製造方法、及び微細中空突起具
CN109310831B (zh) 2016-06-02 2021-11-23 西医药服务以色列有限公司 三位置针缩回
EP3490643B1 (de) 2016-08-01 2021-10-27 West Pharma. Services Il, Ltd. Verdrehsicherungsstift
US11730892B2 (en) 2016-08-01 2023-08-22 West Pharma. Services IL, Ltd. Partial door closure prevention spring
CN117731591A (zh) * 2016-11-21 2024-03-22 艾里奥治疗公司 大试剂的透皮递送
USD819197S1 (en) 2016-12-16 2018-05-29 Kimberly-Clark Worldwide, Inc. Fluid delivery apparatus
EP3554618B1 (de) 2016-12-16 2023-02-01 Sorrento Therapeutics, Inc. Flüssigkeitabgabevorrichtung zur behandlung von migräne oder clusterkopfschmerzen die eine mikronadeleinheit enthält
CN110300612B (zh) 2016-12-16 2022-04-22 索伦托治疗有限公司 具有控制器组件的流体递送装置及其使用方法
USD836774S1 (en) 2016-12-16 2018-12-25 Sorrento Therapeutics, Inc. Cartridge for a fluid delivery apparatus
US10646454B2 (en) 2017-03-24 2020-05-12 E Ink California, Llc Microcell delivery systems including charged or magnetic particles for regulating rate of administration of actives
CN110461314A (zh) 2017-03-24 2019-11-15 伊英克加利福尼亚有限责任公司 用于递送活性分子的微单元系统
DK3606760T3 (da) 2017-03-31 2023-11-06 Vaxxas Pty Ltd Indretning og fremgangsmåde til belægning af overflader
CN110869072B (zh) 2017-05-30 2021-12-10 西部制药服务有限公司(以色列) 用于穿戴式注射器的模块化驱动机构
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP3661587A4 (de) 2017-08-04 2021-06-09 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
US10035010B1 (en) * 2017-09-28 2018-07-31 Carydean Enterprises LLC Systems and methods for drug delivery
TWI682787B (zh) 2017-11-14 2020-01-21 美商伊英克加利福尼亞有限責任公司 包含多孔導電電極層之電泳主動遞送系統
CN114470420A (zh) 2017-12-22 2022-05-13 西氏医药包装(以色列)有限公司 适用于不同尺寸的药筒的注射器
JP6375435B1 (ja) 2017-12-26 2018-08-15 三島光産株式会社 マイクロニードルアレイ
US20210060322A1 (en) * 2018-01-09 2021-03-04 Evonik Corporation Wearable device with microneedle array delivery system
CN111836582A (zh) * 2018-03-16 2020-10-27 国立大学法人东京大学 检测芯片以及检测装置
US10932729B2 (en) 2018-06-06 2021-03-02 Masimo Corporation Opioid overdose monitoring
US11464410B2 (en) 2018-10-12 2022-10-11 Masimo Corporation Medical systems and methods
EP3772332A1 (de) * 2019-08-08 2021-02-10 PKvitality Körperüberwachungssystem mit einer mikronadel
CN114728155A (zh) 2019-11-27 2022-07-08 伊英克加利福尼亚有限责任公司 包括具有电蚀密封层的微单元的有益剂输送系统
EP4120901A1 (de) 2020-03-20 2023-01-25 Masimo Corporation Tragbare vorrichtung zur nichtinvasiven körpertemperaturmessung
AU2021260929A1 (en) * 2020-04-22 2022-11-24 Paul Gilbert Fluid characteristic indicator
CN116322881A (zh) 2020-10-29 2023-06-23 伊英克加利福尼亚有限责任公司 用于递送有益剂的微单元系统
WO2022093547A1 (en) 2020-10-29 2022-05-05 E Ink California, Llc Microcell systems for delivering hydrophilic active molecules
KR102297883B1 (ko) * 2021-02-17 2021-09-03 주식회사 지엘캄퍼니 마이크로 니들조립체
US11915813B2 (en) * 2021-12-09 2024-02-27 Jubilee Biotech Co., Ltd. Medication compliance management method
US11717612B1 (en) 2022-09-14 2023-08-08 Robert Backstein Multi-purpose automatic injector

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3633580A (en) * 1967-01-18 1972-01-11 Knox Lab Inc Hypodermic needle
US3645268A (en) * 1969-12-10 1972-02-29 Dagoberto Capote Disposable, presterilized, self-locating and piercing evacuator with ejector tube
US4969468A (en) 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
EP0390481B1 (de) * 1989-03-23 1996-02-28 Sanyo Chemical Industries Ltd. Chirurgische Heftfolie
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5250067A (en) * 1992-11-30 1993-10-05 Ala Gelfer Body treatment pad having a multiple number of sharpened skin-penetration protuberances
EP0892444B1 (de) 1993-11-02 2004-04-21 Matsushita Electric Industrial Co., Ltd Halbleiterbauelement mit einem Aggregat von Mikro-Nadeln aus Halbleitermaterial
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
DE59505328D1 (de) * 1994-12-09 1999-04-15 Novartis Ag Transdermales system
US5968022A (en) * 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
US5634913A (en) * 1996-01-23 1997-06-03 Stinger; Florence Softening conduit for carrying fluids into and out of the human body
US5899915A (en) * 1996-12-02 1999-05-04 Angiotrax, Inc. Apparatus and method for intraoperatively performing surgery
US5860957A (en) * 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
US5911363A (en) * 1997-03-10 1999-06-15 Spratronics, Inc. Vehicle mounted spray apparatus and method
AU767122B2 (en) 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6554798B1 (en) * 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
WO2000035530A1 (en) 1998-12-18 2000-06-22 Minimed Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
US6217554B1 (en) * 1999-02-12 2001-04-17 Pharmaspec Corporation Methods and apparatus for delivering substances into extravascular tissue
US6689103B1 (en) * 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
WO2001033614A1 (en) 1999-11-02 2001-05-10 University Of Hawaii Method for fabricating arrays of micro-needles
US6406638B1 (en) * 2000-01-06 2002-06-18 The Regents Of The University Of California Method of forming vertical, hollow needles within a semiconductor substrate, and needles formed thereby
US6629949B1 (en) * 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
EP1345646A2 (de) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
US6689100B2 (en) * 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device

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US20040186419A1 (en) 2004-09-23
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AU2002312013A1 (en) 2002-12-23
US6767341B2 (en) 2004-07-27
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US20020193754A1 (en) 2002-12-19
ES2308657T3 (es) 2008-12-01
EP1695734A1 (de) 2006-08-30
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