DE60224287D1 - Lytische reagenzzusammensetzung zur bestimmung kernhaltiger roter blutzellen - Google Patents

Lytische reagenzzusammensetzung zur bestimmung kernhaltiger roter blutzellen

Info

Publication number
DE60224287D1
DE60224287D1 DE60224287T DE60224287T DE60224287D1 DE 60224287 D1 DE60224287 D1 DE 60224287D1 DE 60224287 T DE60224287 T DE 60224287T DE 60224287 T DE60224287 T DE 60224287T DE 60224287 D1 DE60224287 D1 DE 60224287D1
Authority
DE
Germany
Prior art keywords
blood cells
red blood
reagent composition
containing red
lytic reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60224287T
Other languages
English (en)
Other versions
DE60224287T2 (de
Inventor
Yi Li
Jing Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of DE60224287D1 publication Critical patent/DE60224287D1/de
Publication of DE60224287T2 publication Critical patent/DE60224287T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/12—Coulter-counters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1493—Particle size
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60224287T 2001-07-27 2002-07-15 Lytische reagenszusammensetzung zur bestimmung zellkernhaltiger roter blutkörperchen Expired - Lifetime DE60224287T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US917530 2001-07-27
US09/917,530 US6573102B2 (en) 2001-07-27 2001-07-27 Lytic reagent composition for determination of nucleated blood cells
PCT/US2002/022414 WO2003012426A1 (en) 2001-07-27 2002-07-15 Lytic reagent composition for determination of nucleated red blood cells

Publications (2)

Publication Number Publication Date
DE60224287D1 true DE60224287D1 (de) 2008-02-07
DE60224287T2 DE60224287T2 (de) 2009-01-02

Family

ID=25438923

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224287T Expired - Lifetime DE60224287T2 (de) 2001-07-27 2002-07-15 Lytische reagenszusammensetzung zur bestimmung zellkernhaltiger roter blutkörperchen

Country Status (5)

Country Link
US (1) US6573102B2 (de)
EP (1) EP1419381B1 (de)
JP (1) JP4170903B2 (de)
DE (1) DE60224287T2 (de)
WO (1) WO2003012426A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2813891B1 (fr) * 2000-09-14 2005-01-14 Immunotech Sa Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications
US6916658B2 (en) * 2001-07-27 2005-07-12 Beckman Coulter, Inc. Method for measurement of immature granulocytes
US7745219B2 (en) * 2003-07-21 2010-06-29 Siemens Healthcare Diagnostics Inc. Reagent composition for the analysis of residual white blood cells in leuko-reduced blood banking products
WO2005036164A1 (en) * 2003-10-02 2005-04-21 Beckman Coulter, Inc. Reference control for optical measurement of nucleated red blood cells of a blood sample
US7198953B2 (en) * 2003-10-12 2007-04-03 Beckman Coulter, Inc. Method of using a reference control composition for measurement of nucleated red blood cells
EP1682865B1 (de) * 2003-10-12 2018-08-15 Beckman Coulter, Inc. Verfahren zur verwendung einer referenzkontrollzusammensetzung zur messung kernhaltiger roter blutzellen
US7195919B2 (en) * 2003-12-19 2007-03-27 Beckman Coulter, Inc. Hematology controls for reticulocytes and nucleated red blood cells
EP1714146B1 (de) * 2004-02-10 2022-08-03 Beckman Coulter, Inc. Verfahren zur messung kernhaltiger roter blutzellen
US7208319B2 (en) * 2004-02-10 2007-04-24 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US7135341B2 (en) * 2004-04-07 2006-11-14 Beckman Coulter, Inc. Reference control containing a nucleated red blood cell component
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7625712B2 (en) * 2004-05-21 2009-12-01 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
EP1810025B1 (de) * 2004-10-20 2010-04-14 Chempaq A/S Lysereagens zur gleichzeitigen auszählung unterschiedlicher arten von blutzellen in einer blutprobe
EP1655606B1 (de) 2004-11-05 2011-08-10 F. Hoffmann-La Roche AG Biochemisches Gerät und Nachweisverfahren
US7235404B2 (en) * 2005-05-04 2007-06-26 Beckman Coulter, Inc. Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
US7482165B2 (en) 2005-08-24 2009-01-27 Beckman Coulter, Inc. Method of preventing white blood cell interferences to red blood cell measurements of a blood sample
US7609369B2 (en) * 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
US7586589B2 (en) * 2005-09-24 2009-09-08 Beckman Coulter, Inc. Methods of determination of responsiveness to erythropoietin treatment
JP4822562B2 (ja) 2006-01-20 2011-11-24 ベックマン コールター， インコーポレイテッド 低ヘモグロビン濃度細胞百分率および鉄欠乏の検出における使用方法
US7674622B2 (en) * 2006-12-22 2010-03-09 Abbott Laboratories, Inc. Method for determination of nucleated red blood cells and leukocytes in a whole blood sample in an automated hematology analyzer
JP4817450B2 (ja) * 2007-01-31 2011-11-16 シスメックス株式会社 血液分析装置、血液分析方法およびコンピュータプログラム
WO2009058876A1 (en) * 2007-10-29 2009-05-07 Beckman Coulter, Inc. Method for a rapid antibody-based analysis of platelet populations
CN101723874B (zh) * 2008-10-31 2013-09-11 深圳迈瑞生物医疗电子股份有限公司 花菁类化合物及其在生物样品染色中的用途
WO2010054180A1 (en) * 2008-11-07 2010-05-14 Beckman Coulter, Inc. High sensitivity parameters for the detection of vitamin b12 and/or folate deficiencies and methods of use
EP2356465B1 (de) 2008-11-13 2014-10-01 Beckman Coulter, Inc. Verfahren zur korrektur von partikelinterferenz bei hämoglobinmessungen
CN101750476B (zh) * 2008-12-08 2015-06-03 深圳迈瑞生物医疗电子股份有限公司 血液分析试剂及其使用方法
EP2216095A1 (de) 2009-01-27 2010-08-11 Koninklijke Philips Electronics N.V. Mikrofluidische Vorrichtung für die Vollblutzählung
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
EP2571383B1 (de) 2010-05-20 2022-01-26 Ecolab USA Inc. Antimikrobielle flüssigzusammensetzungen mit modifizierter rheologie und geringer schäumung sowie verfahren zu ihrer verwendung
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
CN102226804B (zh) * 2011-03-28 2013-07-03 中国人民解放军总医院 一种用于血液白细胞五分类计数的溶血剂及其用途
CN103620052B (zh) * 2011-06-17 2016-06-01 协和梅迪克斯株式会社 糖化血红蛋白的测定方法、测定试剂和测定试剂盒
WO2016196451A1 (en) 2015-06-01 2016-12-08 The Wistar Institute Of Anatomy And Biology Methods for monitoring polymorphonuclear myeloid derived suppressor cells

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286963A (en) * 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
US4528274A (en) 1982-07-06 1985-07-09 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
CA1255197A (en) * 1984-09-24 1989-06-06 Joseph L. Orlik Leukocyte differentiation composition and method
US5389549A (en) * 1987-05-29 1995-02-14 Toa Medical Electronics Co., Ltd. Method for classifying leukocytes and a reagent used therefor
JP2619900B2 (ja) * 1988-01-27 1997-06-11 東亜医用電子株式会社 血液中の白血球およびヘモグロビンの測定用試薬および方法
JP2836865B2 (ja) * 1989-10-23 1998-12-14 東亜医用電子株式会社 血液中の白血球およびヘモグロビンの測定用試薬
US5242832A (en) * 1990-03-01 1993-09-07 Toa Medical Electronics Co., Ltd. Reagent for measurement of leukocytes and hemoglobin in blood
JP2927979B2 (ja) 1991-02-22 1999-07-28 シスメックス株式会社 フローサイトメトリーによる赤芽球の分類方法
JP2716267B2 (ja) 1993-02-25 1998-02-18 アボツト・ラボラトリーズ 全血試料を高速溶解するための多目的試薬系
JP3320869B2 (ja) * 1993-12-22 2002-09-03 シスメックス株式会社 白血球分析用試薬
EP0749583B1 (de) 1994-03-11 2002-08-28 Abbott Laboratories Cyanidfreies reagens und verfahren zur bestimmung von hämoglobin
US5559037A (en) 1994-12-15 1996-09-24 Abbott Laboratories Method for rapid and simultaneous analysis of nucleated red blood cells
US5834315A (en) * 1994-12-23 1998-11-10 Coulter Corporation Cyanide-free reagent and method for hemoglobin determination and leukocyte differentitation
US5686308A (en) * 1995-06-08 1997-11-11 Coulter Corporation Reagent and method for differential determination of leukocytes in blood
US5882933A (en) 1995-06-08 1999-03-16 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
US5786224A (en) * 1995-06-29 1998-07-28 Coulter Corporation Reagent and method for differential determination of leukocytes in blood
US5817518A (en) * 1995-12-18 1998-10-06 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
US5763280A (en) 1997-01-21 1998-06-09 Coulter International Corp. Cyanide-free lytic reagent composition and method for hemoglobin and cell analysis
US5882934A (en) * 1997-01-21 1999-03-16 Coulter International Corp. Composition and method for hemoglobin and cell analysis
US5874310A (en) 1997-11-21 1999-02-23 Coulter International Corp. Method for differentiation of nucleated red blood cells
US5917584A (en) 1997-11-21 1999-06-29 Coulter International Corp. Method for differentiation of nucleated red blood cells
JP3886271B2 (ja) 1998-11-27 2007-02-28 シスメックス株式会社 赤芽球の分類計数用試薬及び分類計数方法
US6214625B1 (en) * 1999-04-28 2001-04-10 Coulter International Corp. Composition and method for differentiation of basophils and eosinophils in blood
US6210969B1 (en) * 1999-04-28 2001-04-03 Coulter International Corp. Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood
US6410330B1 (en) * 2001-07-27 2002-06-25 Coulter International Corp. Method for measurement of nucleated red blood cells

Also Published As

Publication number Publication date
US6573102B2 (en) 2003-06-03
JP4170903B2 (ja) 2008-10-22
DE60224287T2 (de) 2009-01-02
JP2004537725A (ja) 2004-12-16
EP1419381A4 (de) 2006-11-22
US20030040115A1 (en) 2003-02-27
EP1419381A1 (de) 2004-05-19
WO2003012426A1 (en) 2003-02-13
EP1419381B1 (de) 2007-12-26

Similar Documents

Publication Publication Date Title
DE60224287D1 (de) Lytische reagenzzusammensetzung zur bestimmung kernhaltiger roter blutzellen
DE60221080D1 (de) Vorrichtungen zur Bestimmung der Analytkonzentration und ihre Herstellung und Verwendung
DE69941563D1 (de) Elektrochemisches System zur Bestimmung der Blutgerinnungszeit
DE60143748D1 (de) Verfahren zur selektiven bestimmung von glykosyliertem hämoglobin
DE69839947D1 (de) Cyanidfreie lytische Reagenzzusammensetzung und Vefahren zur Hämoglobin- und Zellanalyse
DE69924968D1 (de) Verfahren zur differenzierung roter nukleierter blutzellen
DE60217264D1 (de) Filtersystem für Blutgefässe
FI20011877A (fi) Menetelmä ja bioanturi analyysiä varten
DE60303886D1 (de) Vorrichtungen zur Bestimmung der Analytkonzentration und ihre Verwendung
ATE324586T1 (de) Nitrit-stabilisierte zusammensetzungen von tetrazolium-reagenz und methoden derer nutzung
DE50103557D1 (de) Assistenzsystem zur auswahl von strecken
ATE399350T1 (de) System zur bestimmung der endgültigen position von zähnen
DE69935314D1 (de) Quantitatitative bestimmung von nucleinsäure-amplifizierungsprodukten
HK1055463A1 (en) Determination of sample volume adequacy in biosensor devices
EP1877802A4 (de) Cyanidfreie lösungsmittelzusammensetzung und verwendungsverfahren dafür zur messung von hämoglobin und weissen blutkörperchen
AU2003226027A1 (en) System for performing blood coagulation assays and measuring blood clotting times
ATE324859T1 (de) Zusammensetzung zur oxidationsfärbung von keratinfasern
DE60237639D1 (de) Methode zur bestimmung der biologischen aktivität von difibrotid
FR2759166B1 (fr) Reactif de coloration pour la determination de cellules sanguines
DE60125958D1 (de) Reagenzien zur bestimmung von atomaren sauerstoff
DE60136781D1 (de) Schaltung zur Bestimmung des Verhältnisses von Verlustleistung zu Signalleistung
DE60234821D1 (de) Messverfahren für vollblut
DE60213940D1 (de) Proben-Einführungssystem
DE10297670D2 (de) Analysegerät zur Bestimmung der chemischen Struktur und/oder Zusammensetzung einer Vielzahl von Proben und Träger zur Aufnahme der Proben
ATE344250T1 (de) Herstellung von makrozyklischen tetraamidoliganden zur verwendung als bleichkatalysatoren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BECKMAN COULTER, INC., BREA, CALIF., US