DE60222773D1 - Kombinationen vom PPAR-Aktivator Fenofibrat mit dem Hemmer der Sterol-Absorption Ezetimibe zur Behandlung von kardiovaskulären Indikationen - Google Patents

Kombinationen vom PPAR-Aktivator Fenofibrat mit dem Hemmer der Sterol-Absorption Ezetimibe zur Behandlung von kardiovaskulären Indikationen

Info

Publication number
DE60222773D1
DE60222773D1 DE60222773T DE60222773T DE60222773D1 DE 60222773 D1 DE60222773 D1 DE 60222773D1 DE 60222773 T DE60222773 T DE 60222773T DE 60222773 T DE60222773 T DE 60222773T DE 60222773 D1 DE60222773 D1 DE 60222773D1
Authority
DE
Germany
Prior art keywords
ezetimibe
inhibitor
combinations
treatment
sterol absorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60222773T
Other languages
English (en)
Other versions
DE60222773T2 (de
Inventor
Teddy Kosoglou
Harry R Davis
Gilles Jean Bernard Picard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26950511&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60222773(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE60222773D1 publication Critical patent/DE60222773D1/de
Publication of DE60222773T2 publication Critical patent/DE60222773T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • A61K31/025Halogenated hydrocarbons carbocyclic
    • A61K31/03Halogenated hydrocarbons carbocyclic aromatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • A61K31/055Phenols the aromatic ring being substituted by halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DE60222773T 2001-01-26 2002-01-25 Kombinationen vom PPAR-Aktivator Fenofibrat mit dem Hemmer der Sterol-Absorption Ezetimibe zur Behandlung von kardiovaskulären Indikationen Expired - Lifetime DE60222773T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26439601P 2001-01-26 2001-01-26
US264396P 2001-01-26
US32383901P 2001-09-21 2001-09-21
US323839P 2001-09-21

Publications (2)

Publication Number Publication Date
DE60222773D1 true DE60222773D1 (de) 2007-11-15
DE60222773T2 DE60222773T2 (de) 2008-07-17

Family

ID=26950511

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60216890T Expired - Lifetime DE60216890T2 (de) 2001-01-26 2002-01-25 Kombinationen von einem hemmer der sterol-absorption und einem ppar-aktivator zur behandlung von kardiovaskulären indikationen
DE60222773T Expired - Lifetime DE60222773T2 (de) 2001-01-26 2002-01-25 Kombinationen vom PPAR-Aktivator Fenofibrat mit dem Hemmer der Sterol-Absorption Ezetimibe zur Behandlung von kardiovaskulären Indikationen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60216890T Expired - Lifetime DE60216890T2 (de) 2001-01-26 2002-01-25 Kombinationen von einem hemmer der sterol-absorption und einem ppar-aktivator zur behandlung von kardiovaskulären indikationen

Country Status (33)

Country Link
US (5) US20020151536A1 (de)
EP (2) EP1413331B1 (de)
JP (4) JP4777602B2 (de)
KR (1) KR100596257B1 (de)
CN (1) CN100509058C (de)
AR (2) AR033855A1 (de)
AT (2) ATE348649T1 (de)
AU (1) AU2002247019C1 (de)
BR (1) BR0206654A (de)
CA (3) CA2562982C (de)
CL (1) CL2004001174A1 (de)
CY (2) CY1108000T1 (de)
CZ (2) CZ309209B6 (de)
DE (2) DE60216890T2 (de)
DK (2) DK1413331T3 (de)
EC (1) ECSP11004702A (de)
ES (2) ES2290562T3 (de)
HK (2) HK1063607A1 (de)
HU (2) HUP0303915A3 (de)
IL (3) IL156445A0 (de)
ME (1) MEP27808A (de)
MX (1) MXPA03006725A (de)
NO (1) NO331512B1 (de)
NZ (1) NZ525921A (de)
PL (1) PL208110B1 (de)
PT (2) PT1413331E (de)
RS (2) RS20100015A (de)
RU (1) RU2356550C2 (de)
SI (2) SI1413331T1 (de)
SK (2) SK288217B6 (de)
TW (1) TWI337083B (de)
WO (1) WO2002058732A2 (de)
ZA (1) ZA200305693B (de)

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AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
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CN104337785A (zh) * 2014-11-04 2015-02-11 万全万特制药江苏有限公司 一种含有依折麦布的口腔崩解片及其制备方法
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