DE60221287D1 - Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung - Google Patents

Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung

Info

Publication number
DE60221287D1
DE60221287D1 DE60221287A DE60221287A DE60221287D1 DE 60221287 D1 DE60221287 D1 DE 60221287D1 DE 60221287 A DE60221287 A DE 60221287A DE 60221287 A DE60221287 A DE 60221287A DE 60221287 D1 DE60221287 D1 DE 60221287D1
Authority
DE
Germany
Prior art keywords
bio
therapeutic agent
intraluminal device
oil
intraluminal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60221287A
Other languages
English (en)
Other versions
DE60221287T4 (de
DE60221287T2 (de
Inventor
Pierre Jacobs
Maria Dhondt
Scheerder Ivan De
Johan Martens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Atrium Medical Corp
Original Assignee
Atrium Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27224430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60221287(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Atrium Medical Corp filed Critical Atrium Medical Corp
Application granted granted Critical
Publication of DE60221287D1 publication Critical patent/DE60221287D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
DE60221287A 2001-11-08 2002-11-08 Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung Expired - Lifetime DE60221287D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP01870237 2001-11-08
EP02447048 2002-03-28
EP02447075 2002-04-26
PCT/BE2002/000166 WO2003039612A1 (en) 2001-11-08 2002-11-08 Intraluminal device with a coating containing a therapeutic agent

Publications (1)

Publication Number Publication Date
DE60221287D1 true DE60221287D1 (de) 2007-08-30

Family

ID=27224430

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60221287A Expired - Lifetime DE60221287D1 (de) 2001-11-08 2002-11-08 Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung
DE60235775T Expired - Lifetime DE60235775D1 (de) 2001-11-08 2002-11-08 Intraluminale Vorrichtung mit einer therapeutisches-mittel enthaltenden Beschichtung
DE60221287T Expired - Lifetime DE60221287T4 (de) 2001-11-08 2002-11-08 Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE60235775T Expired - Lifetime DE60235775D1 (de) 2001-11-08 2002-11-08 Intraluminale Vorrichtung mit einer therapeutisches-mittel enthaltenden Beschichtung
DE60221287T Expired - Lifetime DE60221287T4 (de) 2001-11-08 2002-11-08 Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung

Country Status (9)

Country Link
US (4) US8460693B2 (de)
EP (4) EP1842567A3 (de)
JP (2) JP2005507754A (de)
AT (2) ATE367172T1 (de)
CA (2) CA2466432A1 (de)
DE (3) DE60221287D1 (de)
DK (1) DK1576970T3 (de)
ES (1) ES2289153T7 (de)
WO (1) WO2003039612A1 (de)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7947015B2 (en) 1999-01-25 2011-05-24 Atrium Medical Corporation Application of a therapeutic substance to a tissue location using an expandable medical device
US6955661B1 (en) 1999-01-25 2005-10-18 Atrium Medical Corporation Expandable fluoropolymer device for delivery of therapeutic agents and method of making
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
US20030077310A1 (en) * 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors
CA2466432A1 (en) 2001-11-08 2003-05-15 Atrium Medical Corporation Intraluminal device with a coating containing a therapeutic agent
US7744584B2 (en) 2002-01-22 2010-06-29 Mercator Medsystems, Inc. Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation
US10441747B2 (en) 2002-01-22 2019-10-15 Mercator Medsystems, Inc. Methods and systems for inhibiting vascular inflammation
WO2003061731A2 (en) * 2002-01-22 2003-07-31 Endobionics, Inc. Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia
US8506617B1 (en) 2002-06-21 2013-08-13 Advanced Cardiovascular Systems, Inc. Micronized peptide coated stent
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758880B2 (en) 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
US7279174B2 (en) 2003-05-08 2007-10-09 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
US7169404B2 (en) 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US20050037048A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices containing antioxidant and therapeutic agent
US8021331B2 (en) * 2003-09-15 2011-09-20 Atrium Medical Corporation Method of coating a folded medical device
EP1663343B8 (de) * 2003-09-15 2019-12-04 Atrium Medical Corporation Applikation einer therapeutischen substanz an eine gewebestelle unter verwendung eines expandierbaren medizinprodukts
CN1897891A (zh) * 2003-10-21 2007-01-17 医学技术设备公司 预防再狭窄的γ－生育酚疗法
GB0326180D0 (en) * 2003-11-11 2003-12-17 Leuven K U Res & Dev Biocompatible coating of medical devices
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US8652502B2 (en) * 2003-12-19 2014-02-18 Cordis Corporation Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury
US8747881B2 (en) 2003-12-19 2014-06-10 Cordis Corporation Intraluminal medical devices in combination with therapeutic agents
BRPI0507850A (pt) * 2004-02-28 2007-07-10 Hemoteq Gmbh produto medicinal, método para revestimento biocompatìvel de produtos medicinais
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US9561309B2 (en) 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
US7563780B1 (en) 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
EP1809349B1 (de) * 2004-07-05 2009-10-14 Ziscoat N.V. Biokompatible beschichtung von medizinischen vorrichtungen mit molekularsieben
US7494665B1 (en) 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US20060083768A1 (en) * 2004-09-28 2006-04-20 Atrium Medical Corporation Method of thickening a coating using a drug
US8312836B2 (en) 2004-09-28 2012-11-20 Atrium Medical Corporation Method and apparatus for application of a fresh coating on a medical device
US8367099B2 (en) 2004-09-28 2013-02-05 Atrium Medical Corporation Perforated fatty acid films
US20090011116A1 (en) * 2004-09-28 2009-01-08 Atrium Medical Corporation Reducing template with coating receptacle containing a medical device to be coated
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
WO2006036964A2 (en) * 2004-09-28 2006-04-06 Atrium Medical Corporation Barrier layer
US9801982B2 (en) 2004-09-28 2017-10-31 Atrium Medical Corporation Implantable barrier device
US20060067977A1 (en) 2004-09-28 2006-03-30 Atrium Medical Corporation Pre-dried drug delivery coating for use with a stent
US8603634B2 (en) 2004-10-27 2013-12-10 Abbott Cardiovascular Systems Inc. End-capped poly(ester amide) copolymers
EP1830900A1 (de) * 2004-12-16 2007-09-12 Miv Therapeutics Inc. Mehrschichtige arzneimittelabgabevorrichtung und herstellungsverfahren dafür
US7604818B2 (en) 2004-12-22 2009-10-20 Advanced Cardiovascular Systems, Inc. Polymers of fluorinated monomers and hydrocarbon monomers
DE102005002703C5 (de) * 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
EP1888137A2 (de) * 2005-04-29 2008-02-20 Atrium Medical Corporation Arzneistoffzuführungsbeschichtung zur verwendung mit einer medizinischen vorrichtung sowie verfahren zur behandlung von gefässverletzung
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
CA2626030A1 (en) 2005-10-15 2007-04-26 Atrium Medical Corporation Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings
WO2007131802A1 (en) * 2006-05-17 2007-11-22 Ziscoat Nv Fatty acid triglycerides for making biocompatible coatings
US9561351B2 (en) 2006-05-31 2017-02-07 Advanced Cardiovascular Systems, Inc. Drug delivery spiral coil construct
US8388573B1 (en) 2006-06-28 2013-03-05 Abbott Cardiovascular Systems Inc. Local delivery with a balloon covered by a cage
CA2775940A1 (en) * 2006-07-03 2008-01-10 Hemoteq Ag Catheter balloon with polymeric coating
US9028859B2 (en) 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
DE102006033312A1 (de) * 2006-07-17 2008-01-31 Heraeus Kulzer Gmbh Dentales Implantatsystemteil mit einer Beschichtung
DE102006038233A1 (de) 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Markerkomposit für medizinische Implantate
JP5100084B2 (ja) * 2006-10-26 2012-12-19 株式会社東芝 超音波診断装置、画像処理装置、及び画像処理プログラム
JP2010508897A (ja) * 2006-11-06 2010-03-25 アトリウム メディカル コーポレーション コーティングされた外科用メッシュ
US9492596B2 (en) 2006-11-06 2016-11-15 Atrium Medical Corporation Barrier layer with underlying medical device and one or more reinforcing support structures
JP2008119199A (ja) * 2006-11-10 2008-05-29 Kagoshima Univ カルシニューリン産生亢進を抑制する薬剤コーティングステント
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
WO2008063576A2 (en) * 2006-11-20 2008-05-29 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US20080175887A1 (en) 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
US8425459B2 (en) 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8414525B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
EP2136853B1 (de) 2007-01-21 2013-04-10 Hemoteq AG Medizinprodukt zur behandlung von verschlüssen von körperdurchgängen und zur prävention drohender wiederverschlüsse
US8932345B2 (en) * 2007-02-07 2015-01-13 Cook Medical Technologies Llc Medical device coatings for releasing a therapeutic agent at multiple rates
US7938286B2 (en) * 2007-02-13 2011-05-10 Gateway Plastics, Inc. Container system
US20080207756A1 (en) * 2007-02-27 2008-08-28 Atrium Medical Corporation Bio-absorbable oil suspension
US9056155B1 (en) 2007-05-29 2015-06-16 Abbott Cardiovascular Systems Inc. Coatings having an elastic primer layer
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
DE102007036685A1 (de) 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
DE102007040868A1 (de) 2007-08-29 2009-04-16 Innora Gmbh Ballonkatheter mit Schutz vor Auffaltung
US8100855B2 (en) 2007-09-17 2012-01-24 Abbott Cardiovascular Systems, Inc. Methods and devices for eluting agents to a vessel
WO2009041691A1 (ja) * 2007-09-28 2009-04-02 Terumo Kabushiki Kaisha 生体内留置物
CA2702183A1 (en) * 2007-10-10 2009-04-16 Miv Therapeutics Inc. Lipid coatings for implantable medical devices
US8916188B2 (en) 2008-04-18 2014-12-23 Abbott Cardiovascular Systems Inc. Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
DE102008020415A1 (de) 2008-04-24 2009-10-29 Biotronik Vi Patent Ag Biodegradierbare metallische Stents mit Wachsschicht
WO2010024898A2 (en) 2008-08-29 2010-03-04 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US8226603B2 (en) 2008-09-25 2012-07-24 Abbott Cardiovascular Systems Inc. Expandable member having a covering formed of a fibrous matrix for intraluminal drug delivery
US8076529B2 (en) 2008-09-26 2011-12-13 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix for intraluminal drug delivery
US8049061B2 (en) 2008-09-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Expandable member formed of a fibrous matrix having hydrogel polymer for intraluminal drug delivery
US8500687B2 (en) 2008-09-25 2013-08-06 Abbott Cardiovascular Systems Inc. Stent delivery system having a fibrous matrix covering with improved stent retention
US8728150B2 (en) * 2009-01-21 2014-05-20 Meril Life Sciences Private Limited Medical device loaded with formulation for targeted delivery of biologically active material/s and method of manufacture thereof
EP3064230B1 (de) 2009-07-10 2019-04-10 Boston Scientific Scimed, Inc. Verwendung von nanokristallen für einen wirkstofffreisetzungsballon
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 薬剤送達バルーンの製造方法
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US20110045050A1 (en) * 2009-08-24 2011-02-24 Atrium Medical Corporation Nanoemulsion formulations for direct delivery
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
US8927000B2 (en) * 2010-06-30 2015-01-06 Surmodics, Inc. Lipid coating for medical devices delivering bioactive agent
US10322213B2 (en) 2010-07-16 2019-06-18 Atrium Medical Corporation Compositions and methods for altering the rate of hydrolysis of cured oil-based materials
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
WO2013007273A1 (en) 2011-07-08 2013-01-17 Cardionovum Sp.Z.O.O. Balloon surface coating
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
WO2013091722A1 (en) 2011-12-23 2013-06-27 Innora Gmbh Drug-coated medical devices
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
US20150231306A1 (en) * 2014-02-19 2015-08-20 Lenn R. Hann Coated medical device
US10390831B2 (en) * 2015-11-10 2019-08-27 Covidien Lp Endoscopic reposable surgical clip applier
CA3035774A1 (en) 2016-09-22 2018-03-29 Mercator Medsystems, Inc. Treatment of restenosis using temsirolimus
CN110996687A (zh) 2017-05-26 2020-04-10 墨卡托医疗系统公司 用于治疗再狭窄的联合疗法
WO2019178231A1 (en) 2018-03-14 2019-09-19 Mercator Medsystems, Inc. Medical instrument and medical method for localized drug delivery

Family Cites Families (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950124A (de) * 1972-09-27 1974-05-15
DE2828623C2 (de) * 1978-06-29 1983-11-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung
SE8206744D0 (sv) * 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
SU1297865A1 (ru) * 1984-05-04 1987-03-23 Ленинградский Государственный Институт Усовершенствования Врачей Им.С.М.Кирова Способ лечени больных хроническим неспецифическим звенным колитом
HU193951B (en) * 1985-03-11 1987-12-28 Richter Gedeon Vegyeszet Process for producing new sulfur-containing 5-substituted benzimidazol derivatives and pharmaceutical compositions containing them
JPS61291520A (ja) * 1985-06-19 1986-12-22 Daigo Eiyou Kagaku Kk エリスロマイシン脂肪乳剤
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4847301A (en) * 1985-11-13 1989-07-11 Pennwalt Corporation Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
US5118493A (en) * 1986-05-02 1992-06-02 Brigham And Women's Hospital Composition having reduced nephrotoxocity comprising a fatty acid containing component and cyclosporine
US5371109A (en) 1986-07-01 1994-12-06 Drilletten Ab Controlled release composition for a biologically active material dissolved or dispersed in an L2-phase
US6387379B1 (en) * 1987-04-10 2002-05-14 University Of Florida Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like
US4894231A (en) * 1987-07-28 1990-01-16 Biomeasure, Inc. Therapeutic agent delivery system
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
DE3734147C2 (de) * 1987-10-09 1998-10-29 Braun Melsungen Ag Isotone omega-3-fettsäurenhaltige Fettemulsion und ihre Verwendung
US6146358A (en) * 1989-03-14 2000-11-14 Cordis Corporation Method and apparatus for delivery of therapeutic agent
US5843089A (en) * 1990-12-28 1998-12-01 Boston Scientific Corporation Stent lining
CA2380683C (en) 1991-10-28 2006-08-08 Advanced Cardiovascular Systems, Inc. Expandable stents and method for making same
DE4222380A1 (de) * 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker In den Körper eines Patienten perkutan implantierbare Endoprothese
US5283257A (en) * 1992-07-10 1994-02-01 The Board Of Trustees Of The Leland Stanford Junior University Method of treating hyperproliferative vascular disease
US6491938B2 (en) * 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
FR2710161B1 (fr) * 1993-09-13 1995-11-24 Suisse Electronique Microtech Réseau miniature d'obturateurs de lumière.
DE69431071T2 (de) * 1993-12-29 2003-03-20 Matrix Pharma Zusammensetzung für lokale freigabe von zytostatika
US6228383B1 (en) * 1994-03-03 2001-05-08 Gs Development Ab Use of fatty acid esters as bioadhesive substances
EP0752855B1 (de) * 1994-03-30 1999-06-09 Gs Development Ab Verwendung von fettsäureester als bioklebstoffe
US5716614A (en) 1994-08-05 1998-02-10 Molecular/Structural Biotechnologies, Inc. Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-conjugated polycationic carrier
US5591230A (en) * 1994-09-07 1997-01-07 Global Therapeutics, Inc. Radially expandable stent
SE518619C2 (sv) * 1994-12-09 2002-10-29 Gs Dev Ab Komposition för reglerad frisättning innehållande monokaproin
US5891108A (en) * 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
DE4432708A1 (de) * 1994-09-14 1996-03-21 Hoechst Ag Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
US5509899A (en) * 1994-09-22 1996-04-23 Boston Scientific Corp. Medical device with lubricious coating
US5637113A (en) 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
US6004549A (en) 1994-12-14 1999-12-21 Schering Corporation Crystalline protein controlled release compositions
US6262109B1 (en) * 1995-12-22 2001-07-17 Henkel Corporation Methods of preventing and/or treating high serum levels of cholesterol and/or lipids
US5496832A (en) 1995-03-09 1996-03-05 American Home Products Corporation Method of treating cardiac inflammatory disease
US5605696A (en) * 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
SE504582C2 (sv) 1995-07-06 1997-03-10 Gs Dev Ab Cyklosporinkomposition baserad på en L2-fas
RU2125887C1 (ru) * 1995-08-25 1999-02-10 Владивостокский государственный медицинский университет Способ приготовления липосомального интерферона
US5714360A (en) * 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
US6764509B2 (en) * 1996-09-06 2004-07-20 Carbomedics Inc. Prosthetic heart valve with surface modification
PL190181B1 (pl) 1996-10-11 2005-11-30 Scarista Ltd Zastosowanie oleju zawierającego kwas eikozapentaenowy (KEP) i/lub kwas stearydonowy (KS) oraz preparat farmaceutyczny zawierający olej
ZA9710342B (en) 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US5843172A (en) 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
ES2202870T3 (es) * 1997-05-29 2004-04-01 K.U. LEUVEN RESEARCH & DEVELOPMENT Eliminacion de compuestos de acidos grasos trans-insaturados mediante adsorcion selectiva con zeolitas.
AU8293498A (en) * 1997-07-02 1999-01-25 Euro-Celtique S.A. Stabilized sustained release tramadol formulations
US5897911A (en) * 1997-08-11 1999-04-27 Advanced Cardiovascular Systems, Inc. Polymer-coated stent structure
US6083950A (en) * 1997-11-13 2000-07-04 Ranbaxy Laboratories Limited 1-(4-arylpiperazin-1-yl)-ω-[n-(α,ω-dicarboximido)]-alka nes useful as uro-selective α1-adrenoceptor blockers
CA2313024C (en) * 1997-12-10 2008-06-03 Severson, Mary L. Pharmaceutical compositions containing an omega-3 fatty acid oil
US6033436A (en) * 1998-02-17 2000-03-07 Md3, Inc. Expandable stent
US6465525B1 (en) * 1998-03-18 2002-10-15 Surmodics, Inc. Latent reactive blood compatible agents
DE19916086B4 (de) 1998-04-11 2004-11-11 Inflow Dynamics Inc. Implantierbare Prothese, insbesondere Gefäßprothese (Stent)
US6206916B1 (en) * 1998-04-15 2001-03-27 Joseph G. Furst Coated intraluminal graft
US6197357B1 (en) * 1998-05-28 2001-03-06 University Of Massachusetts Refined vegetable oils and extracts thereof
ATE255427T1 (de) * 1998-06-03 2003-12-15 Blue Medical Devices B V Stents mit diamantartiger beschichtung
US6254634B1 (en) * 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
US6369039B1 (en) * 1998-06-30 2002-04-09 Scimed Life Sytems, Inc. High efficiency local drug delivery
WO2000010622A1 (en) * 1998-08-20 2000-03-02 Cook Incorporated Coated implantable medical device
US6211315B1 (en) * 1998-11-12 2001-04-03 Iowa State University Research Foundation, Inc. Lewis acid-catalyzed polymerization of biological oils and resulting polymeric materials
EP1140243B1 (de) 1998-12-31 2003-04-09 Angiotech Pharmaceuticals, Inc. Stent-transplantate mit bioaktiven beschichtungen
DE19900054A1 (de) * 1999-01-04 2000-07-06 Hans Dietl Taxane enthaltende stabile und sterile Emulsion und Verfahren zu ihrer Herstellung
AU3722800A (en) * 1999-03-04 2000-09-21 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
CN1167462C (zh) * 1999-03-09 2004-09-22 杭州华东医药集团生物工程研究所有限公司 一种含环孢素的药物组合物
US6607598B2 (en) * 1999-04-19 2003-08-19 Scimed Life Systems, Inc. Device for protecting medical devices during a coating process
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6730349B2 (en) * 1999-04-19 2004-05-04 Scimed Life Systems, Inc. Mechanical and acoustical suspension coating of medical implants
US6610035B2 (en) * 1999-05-21 2003-08-26 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hybrid top coat
JP4421699B2 (ja) * 1999-06-30 2010-02-24 大洋薬品工業株式会社 静脈注射可能なプロスタグランジン脂肪乳剤
US6503556B2 (en) * 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
JP2004505886A (ja) * 2000-02-18 2004-02-26 スィーヴィー　セラピューティクス　インコーポレイテッド 鬱血性心不全の処置における部分的な脂肪酸酸化阻害剤
EP1132058A1 (de) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravaskuläre Prothese
US20040039441A1 (en) * 2002-05-20 2004-02-26 Rowland Stephen Maxwell Drug eluting implantable medical device
US6527801B1 (en) * 2000-04-13 2003-03-04 Advanced Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
US7875283B2 (en) * 2000-04-13 2011-01-25 Advanced Cardiovascular Systems, Inc. Biodegradable polymers for use with implantable medical devices
US7419678B2 (en) 2000-05-12 2008-09-02 Cordis Corporation Coated medical devices for the prevention and treatment of vascular disease
US6776796B2 (en) * 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US6670355B2 (en) 2000-06-16 2003-12-30 Wyeth Method of treating cardiovascular disease
US6451373B1 (en) * 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
CA2425665C (en) * 2000-10-31 2013-07-16 Cook Incorporated Coated implantable medical device
US6471980B2 (en) * 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
US7056339B2 (en) * 2001-04-20 2006-06-06 The Board Of Trustees Of The Leland Stanford Junior University Drug delivery platform
US20030189927A1 (en) * 2001-04-27 2003-10-09 Foster Michael S. Method and system for multiframe buffering in a routing device
WO2002100455A2 (en) * 2001-06-08 2002-12-19 Baylor College Of Medicine Use of ozone for the prevention of infection caused by medical devices
US6787179B2 (en) * 2001-06-29 2004-09-07 Ethicon, Inc. Sterilization of bioactive coatings
US7034037B2 (en) * 2001-06-29 2006-04-25 Ethicon, Inc. Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin
US7030127B2 (en) 2001-06-29 2006-04-18 Ethicon, Inc. Composition and medical devices utilizing bioabsorbable polymeric waxes
EP1273314A1 (de) * 2001-07-06 2003-01-08 Terumo Kabushiki Kaisha Stent
US6444318B1 (en) * 2001-07-17 2002-09-03 Surmodics, Inc. Self assembling monolayer compositions
US20040137066A1 (en) * 2001-11-26 2004-07-15 Swaminathan Jayaraman Rationally designed therapeutic intravascular implant coating
US6641611B2 (en) 2001-11-26 2003-11-04 Swaminathan Jayaraman Therapeutic coating for an intravascular implant
US20030077310A1 (en) * 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors
CA2466432A1 (en) * 2001-11-08 2003-05-15 Atrium Medical Corporation Intraluminal device with a coating containing a therapeutic agent
US6663880B1 (en) 2001-11-30 2003-12-16 Advanced Cardiovascular Systems, Inc. Permeabilizing reagents to increase drug delivery and a method of local delivery
US20030204168A1 (en) * 2002-04-30 2003-10-30 Gjalt Bosma Coated vascular devices
US7048962B2 (en) * 2002-05-02 2006-05-23 Labcoat, Ltd. Stent coating device
US6645547B1 (en) 2002-05-02 2003-11-11 Labcoat Ltd. Stent coating device
AU2003251787A1 (en) 2002-07-02 2004-01-23 Polycord, Inc. Polymerized and modified rapamycins and their use in coating medical prostheses
US6767405B2 (en) 2002-07-10 2004-07-27 Carmeda Ab Apparatus and process for coating articles
AU2003256540B2 (en) 2002-07-12 2008-12-11 Cook Medical Technologies Llc Coated medical device
US7732535B2 (en) * 2002-09-05 2010-06-08 Advanced Cardiovascular Systems, Inc. Coating for controlled release of drugs from implantable medical devices
US6899729B1 (en) * 2002-12-18 2005-05-31 Advanced Cardiovascular Systems, Inc. Stent for treating vulnerable plaque
US20040224003A1 (en) 2003-02-07 2004-11-11 Schultz Robert K. Drug formulations for coating medical devices
US20040167572A1 (en) * 2003-02-20 2004-08-26 Roth Noah M. Coated medical devices
WO2004075781A2 (en) * 2003-02-26 2004-09-10 Medivas, Llc Bioactive stents and methods for use thereof
US20040230176A1 (en) 2003-04-23 2004-11-18 Medtronic Vascular, Inc. System for treating a vascular condition that inhibits restenosis at stent ends
US8021418B2 (en) 2003-06-19 2011-09-20 Boston Scientific Scimed, Inc. Sandwiched radiopaque marker on covered stent
JP2007502135A (ja) 2003-08-14 2007-02-08 ブルー・メディカル・デバイシーズ・ベスローテン・フェンノートシャップ 治療剤を含んで成る腔内人工器官
GB0326180D0 (en) 2003-11-11 2003-12-17 Leuven K U Res & Dev Biocompatible coating of medical devices
US8747881B2 (en) 2003-12-19 2014-06-10 Cordis Corporation Intraluminal medical devices in combination with therapeutic agents
US7303758B2 (en) 2004-01-20 2007-12-04 Cordis Corporation Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury
US20050159809A1 (en) * 2004-01-21 2005-07-21 Medtronic Vascular, Inc. Implantable medical devices for treating or preventing restenosis
US7806924B2 (en) * 2004-02-18 2010-10-05 Cordis Corporation Implantable structures for local vascular delivery of cladribine in combination with rapamycin for restenosis
US8139270B2 (en) 2007-05-31 2012-03-20 Xerox Corporation Variable data periodic line patterns for composing a font system

Also Published As

Publication number Publication date
EP1842567A3 (de) 2008-01-02
EP1463545B1 (de) 2007-07-18
EP1576970A1 (de) 2005-09-21
CA2466432A1 (en) 2003-05-15
DE60235775D1 (de) 2010-05-06
EP2201965A1 (de) 2010-06-30
JP2006051369A (ja) 2006-02-23
EP1463545A1 (de) 2004-10-06
DE60221287T4 (de) 2009-06-25
ES2289153T3 (es) 2008-02-01
EP1463545B3 (de) 2008-12-10
WO2003039612A1 (en) 2003-05-15
US20050158361A1 (en) 2005-07-21
US20060008501A1 (en) 2006-01-12
DK1576970T3 (da) 2010-07-12
DE60221287T2 (de) 2008-04-03
ES2289153T7 (es) 2009-06-18
US20130274319A1 (en) 2013-10-17
ATE461717T1 (de) 2010-04-15
EP1576970B1 (de) 2010-03-24
EP1842567A2 (de) 2007-10-10
CA2508907A1 (en) 2003-05-15
US8460693B2 (en) 2013-06-11
US20100209473A1 (en) 2010-08-19
JP2005507754A (ja) 2005-03-24
ATE367172T1 (de) 2007-08-15

Similar Documents

Publication Publication Date Title
DE60221287D1 (de) Intraluminale vorrichtung mit einer ein therapeutisches-mittel enthaltenden beschichtung
ATE509641T1 (de) Beschichtung für implantierbare vorrichtungen und verfahren zu ihrer herstellung
ATE448812T1 (de) Beschichtung von stents mit verzögerter wirkstofffreisetzung
DE602005018178D1 (de) Phospholipid und verunreinigungsbeständige beschichtungszusammensetzungen
ITRM20020596A0 (it) Protesi vascolare ad impianto con tecnica combinata, laparoscopica edendovascolare, per la cura degli aneurismi dell'aorta addominale, e co
WO2003009778A3 (en) Methods and devices for delivery of therapeutic capable agents with variable release profile
UA86942C2 (ru) N-гетероциклилфенилзамещенные циклические кетоенолы и способ их получения
DE10294792D2 (de) Beschichtung von Stents zur Verhinderung von Restenose
ATE358505T1 (de) Beschichtete endovaskuläre vorrichtung
ATE407709T1 (de) Medizinische prothesevorrichtungen mit verbesserer biokompatibilität
WO2006104894A3 (en) Coating for implantable devices and a method of forming the same
ATE544447T1 (de) Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung
EP1648339A4 (de) Implantierbare prothesenvorrichtungen insbesondere für die transarterielle abgabe bei der behandlung von aortenstenose und implantationsverfahren für diese vorrichtungen
DE602004012816D1 (de) Selbstexpandierbarer Stent und Stenteinbringungssystem zur Behandlung von Gefässerkrankungen
AU2003220970A1 (en) Diamino-pyrimidines and their use as angiogenesis inhibitors
WO2004098455A3 (en) Bifurcated medical appliance delivery apparatus and method
WO2007015739A3 (en) Pea-tempo/pea-bz coatings for controlled delivery of drugs from implantable medical devices
EP2281561A3 (de) Verwendung von LCK-Hemmern zur Behandlung von Immunerkrankungen
MXPA05008461A (es) Equipo para aplicar revestimiento de farmaco a un dispositivo medico en un cuarto del cirujano.
ATE438361T1 (de) Stent beschichtet mit dna
EP1600122A3 (de) Verfahren und Vorrichtung zur Behandlung von Aneurysmen
BR0313915A (pt) Enxerto stent flexìvel
PL1809270T3 (pl) Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi
CY1105317T1 (el) Χρηση υποκατεστημενων ενωσεων 6-διμεθυλαμινομεθυλο-1-φαινυλο-κυκλοεξανιου για τη θepαπεια της ακρατειας ουρων
NO20054034L (no) Fremgangsmate for behandling av hypotyroidisme.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: WAGNER + HELBIG PATENTANWAELTE, 80538 MUENCHEN