DE602005010840D1 - Thioamidderivate als progesteronrezeptormodulatoren - Google Patents
Thioamidderivate als progesteronrezeptormodulatorenInfo
- Publication number
- DE602005010840D1 DE602005010840D1 DE602005010840T DE602005010840T DE602005010840D1 DE 602005010840 D1 DE602005010840 D1 DE 602005010840D1 DE 602005010840 T DE602005010840 T DE 602005010840T DE 602005010840 T DE602005010840 T DE 602005010840T DE 602005010840 D1 DE602005010840 D1 DE 602005010840D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor modulators
- thioamid
- derivatives
- progesterone receptor
- thioamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56056904P | 2004-04-08 | 2004-04-08 | |
PCT/US2005/011757 WO2005100346A1 (en) | 2004-04-08 | 2005-04-07 | Thioamide derivatives as progesterone receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005010840D1 true DE602005010840D1 (de) | 2008-12-18 |
Family
ID=34965700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005010840T Active DE602005010840D1 (de) | 2004-04-08 | 2005-04-07 | Thioamidderivate als progesteronrezeptormodulatoren |
Country Status (14)
Country | Link |
---|---|
US (4) | US7358246B2 (de) |
EP (1) | EP1732921B1 (de) |
JP (1) | JP4869221B2 (de) |
CN (1) | CN100522960C (de) |
AT (1) | ATE413398T1 (de) |
AU (1) | AU2005233591B2 (de) |
BR (1) | BRPI0509209A (de) |
CA (1) | CA2561014C (de) |
DE (1) | DE602005010840D1 (de) |
DK (1) | DK1732921T3 (de) |
ES (1) | ES2317223T3 (de) |
MX (1) | MXPA06011696A (de) |
PL (1) | PL1732921T3 (de) |
WO (1) | WO2005100346A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4950027B2 (ja) * | 2004-04-08 | 2012-06-13 | ワイス・エルエルシー | チオアミド不純物を最小限に抑えるための方法 |
BRPI0509209A (pt) * | 2004-04-08 | 2007-08-28 | Wyeth Corp | composto, métodos para contracepção, terapia de reposição hormonal, tratamento ou prevenção de doença neoplásica dependente de hormÈnios; tratamento de sangramento disfuncional ou da sìndrome de ovários policìsticos; sincronização do estro; tratamento da acne ou tratamento do hirsutismo, e para preparação do composto, composição farmacêutica, kit farmacêutico, e, uso de um composto |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
US20070093548A1 (en) * | 2005-10-25 | 2007-04-26 | Wyeth | Use of progesterone receptor modulators |
WO2008021338A2 (en) * | 2006-08-15 | 2008-02-21 | Wyeth | Tricyclic oxazolidone derivatives useful as pr modulators |
JP2011507853A (ja) * | 2007-12-20 | 2011-03-10 | テバ ウィメンズ ヘルス インコーポレイテッド | 緊急避妊のための投与量レジメンならびに薬学的組成物およびパッケージ |
CN107281215A (zh) * | 2016-04-01 | 2017-10-24 | 复旦大学附属妇产科医院 | 硫化氢供体硫氢化钠在制药中的用途 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) * | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4008719A (en) * | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US4295987A (en) * | 1979-12-26 | 1981-10-20 | The Procter & Gamble Company | Cross-linked sodium polyacrylate absorbent |
US4959217A (en) * | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
AU608891B2 (en) | 1987-09-24 | 1991-04-18 | Merck & Co., Inc. | Solubility modulated drug delivery device |
US5273752A (en) * | 1989-07-18 | 1993-12-28 | Alza Corporation | Controlled release dispenser comprising beneficial agent |
US5124455A (en) * | 1990-08-08 | 1992-06-23 | American Home Products Corporation | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents |
US5459151A (en) * | 1993-04-30 | 1995-10-17 | American Home Products Corporation | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents |
US5854388A (en) * | 1993-06-24 | 1998-12-29 | Washington State University Research Foundation | Angiotensin IV peptides and receptor |
US5817343A (en) * | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
US5756127A (en) * | 1996-10-29 | 1998-05-26 | Wright Medical Technology, Inc. | Implantable bioresorbable string of calcium sulfate beads |
FI971385A0 (fi) | 1997-04-04 | 1997-04-04 | Bioxid Oy | Biokompatibel komposition, metoder foer dess framstaellning samt anvaendning daerav |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6417214B1 (en) * | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
HUP0203332A3 (en) * | 1999-05-04 | 2004-12-28 | Wyeth Corp | Cyclothiocarbamate derivatives, their use as progesterone receptor modulators and pharmaceutical compositions containing them |
NZ515351A (en) * | 1999-05-04 | 2004-01-30 | American Home Prod | Thio-oxindole derivatives |
US6355648B1 (en) * | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
US6509334B1 (en) * | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
US6518306B1 (en) * | 1999-08-10 | 2003-02-11 | Smithkline Beecham Corporation | 1,4-substitued 4,4-diaryl cyclohexanes |
US6258833B1 (en) * | 1999-12-23 | 2001-07-10 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
JP4716547B2 (ja) * | 2000-08-10 | 2011-07-06 | 住友精化株式会社 | 2−フェニルチアゾール類の製造方法 |
US20030225273A1 (en) * | 2002-03-21 | 2003-12-04 | Michaelides Michael R. | Thiopyrimidine and isothiazolopyrimidine kinase inhibitors |
KR100985160B1 (ko) * | 2002-06-06 | 2010-10-05 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신규한 축합된 이미다졸 유도체 |
BR0312054A (pt) * | 2002-06-25 | 2005-10-18 | Wyeth Corp | Uso de derivados de tio-oxindol na preparação de medicamentos úteis no tratamento de condições relacionadas com hormÈnio, e kit farmacêutico |
AU2003258952A1 (en) * | 2002-06-25 | 2004-01-06 | Wyeth | Use of thio-oxindole derivatives in treatment of skin disorders |
CN1662241A (zh) | 2002-06-25 | 2005-08-31 | 惠氏公司 | 环硫代氨基甲酸酯衍生物在治疗与激素有关的病症中的用途 |
WO2004000230A2 (en) * | 2002-06-25 | 2003-12-31 | Wyeth | Cyclothiocarbamative derivatives as pr modulators and use thereof for treatment of skin disorders |
BRPI0509209A (pt) * | 2004-04-08 | 2007-08-28 | Wyeth Corp | composto, métodos para contracepção, terapia de reposição hormonal, tratamento ou prevenção de doença neoplásica dependente de hormÈnios; tratamento de sangramento disfuncional ou da sìndrome de ovários policìsticos; sincronização do estro; tratamento da acne ou tratamento do hirsutismo, e para preparação do composto, composição farmacêutica, kit farmacêutico, e, uso de um composto |
JP4950027B2 (ja) * | 2004-04-08 | 2012-06-13 | ワイス・エルエルシー | チオアミド不純物を最小限に抑えるための方法 |
US7122705B2 (en) | 2004-04-08 | 2006-10-17 | Wyeth | Method for preparing 3-cyclopentyloxy-4-methoxybenzaldehyde |
AU2005237520B2 (en) | 2004-04-27 | 2012-01-19 | Wyeth | Purification of progesterone receptor modulators |
-
2005
- 2005-04-07 BR BRPI0509209-4A patent/BRPI0509209A/pt not_active IP Right Cessation
- 2005-04-07 ES ES05735464T patent/ES2317223T3/es active Active
- 2005-04-07 CA CA2561014A patent/CA2561014C/en not_active Expired - Fee Related
- 2005-04-07 WO PCT/US2005/011757 patent/WO2005100346A1/en active Application Filing
- 2005-04-07 MX MXPA06011696A patent/MXPA06011696A/es active IP Right Grant
- 2005-04-07 US US11/100,860 patent/US7358246B2/en not_active Expired - Fee Related
- 2005-04-07 EP EP05735464A patent/EP1732921B1/de not_active Not-in-force
- 2005-04-07 JP JP2007507494A patent/JP4869221B2/ja not_active Expired - Fee Related
- 2005-04-07 DK DK05735464T patent/DK1732921T3/da active
- 2005-04-07 PL PL05735464T patent/PL1732921T3/pl unknown
- 2005-04-07 AU AU2005233591A patent/AU2005233591B2/en not_active Ceased
- 2005-04-07 CN CNB2005800108301A patent/CN100522960C/zh not_active Expired - Fee Related
- 2005-04-07 DE DE602005010840T patent/DE602005010840D1/de active Active
- 2005-04-07 AT AT05735464T patent/ATE413398T1/de not_active IP Right Cessation
-
2008
- 2008-03-07 US US12/044,287 patent/US7511071B2/en not_active Expired - Fee Related
-
2009
- 2009-02-12 US US12/369,789 patent/US7659265B2/en not_active Expired - Fee Related
-
2010
- 2010-02-02 US US12/698,472 patent/US8168672B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1732921B1 (de) | 2008-11-05 |
PL1732921T3 (pl) | 2009-04-30 |
ES2317223T3 (es) | 2009-04-16 |
ATE413398T1 (de) | 2008-11-15 |
US7659265B2 (en) | 2010-02-09 |
JP4869221B2 (ja) | 2012-02-08 |
MXPA06011696A (es) | 2006-12-14 |
EP1732921A1 (de) | 2006-12-20 |
US20100197645A1 (en) | 2010-08-05 |
WO2005100346A1 (en) | 2005-10-27 |
BRPI0509209A (pt) | 2007-08-28 |
CN100522960C (zh) | 2009-08-05 |
JP2007532564A (ja) | 2007-11-15 |
US7358246B2 (en) | 2008-04-15 |
CN1938299A (zh) | 2007-03-28 |
US20080167299A1 (en) | 2008-07-10 |
US20050227971A1 (en) | 2005-10-13 |
DK1732921T3 (da) | 2009-02-23 |
CA2561014A1 (en) | 2005-10-27 |
US20090143345A1 (en) | 2009-06-04 |
CA2561014C (en) | 2013-09-10 |
US8168672B2 (en) | 2012-05-01 |
US7511071B2 (en) | 2009-03-31 |
AU2005233591B2 (en) | 2011-10-27 |
AU2005233591A1 (en) | 2005-10-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |