DE602004022150D1 - Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung - Google Patents

Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung

Info

Publication number
DE602004022150D1
DE602004022150D1 DE602004022150T DE602004022150T DE602004022150D1 DE 602004022150 D1 DE602004022150 D1 DE 602004022150D1 DE 602004022150 T DE602004022150 T DE 602004022150T DE 602004022150 T DE602004022150 T DE 602004022150T DE 602004022150 D1 DE602004022150 D1 DE 602004022150D1
Authority
DE
Germany
Prior art keywords
ngal
cell injury
renal
kit
nierentubulus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004022150T
Other languages
English (en)
Inventor
Prased Devarajan
Jonathan M Barasch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cincinnati Childrens Hospital Medical Center
Columbia University of New York
Original Assignee
Cincinnati Childrens Hospital Medical Center
Columbia University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33135089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602004022150(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cincinnati Childrens Hospital Medical Center, Columbia University of New York filed Critical Cincinnati Childrens Hospital Medical Center
Publication of DE602004022150D1 publication Critical patent/DE602004022150D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
DE602004022150T 2003-03-27 2004-03-26 Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung Expired - Lifetime DE602004022150D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45814303P 2003-03-27 2003-03-27
US48159603P 2003-11-04 2003-11-04
PCT/US2004/009191 WO2004088276A2 (en) 2003-03-27 2004-03-26 A method and kit for detecting the early onset of renal tubular cell injury

Publications (1)

Publication Number Publication Date
DE602004022150D1 true DE602004022150D1 (de) 2009-09-03

Family

ID=33135089

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004022150T Expired - Lifetime DE602004022150D1 (de) 2003-03-27 2004-03-26 Verfahren und kit zum nachweis des frühstadiums einer nierentubuluszellenverletzung

Country Status (14)

Country Link
US (11) US20040219603A1 (de)
EP (3) EP2083270B1 (de)
JP (2) JP5392980B2 (de)
CN (1) CN102183656B (de)
AT (1) ATE437371T1 (de)
AU (1) AU2004225472B2 (de)
BR (1) BRPI0408802B8 (de)
CA (1) CA2520658A1 (de)
DE (1) DE602004022150D1 (de)
DK (2) DK2360475T3 (de)
ES (3) ES2330005T5 (de)
MX (1) MXPA05010385A (de)
NZ (1) NZ543028A (de)
WO (1) WO2004088276A2 (de)

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ES2330005T5 (es) * 2003-03-27 2018-06-20 Children's Hospital Medical Center Un método y kit para la detección de la instauración precoz de la lesión de células tubulares renales
ATE448484T1 (de) * 2004-12-20 2009-11-15 Antibodyshop As Bestimmung von neutrophilem gelatinase- assoziiertem lipocalin (ngal) als diagnostischer marker für nierenerkrankungen
US7977110B2 (en) * 2008-06-02 2011-07-12 Children's Hospital Medical Center Method for distinguishing between kidney dysfunctions

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US20090123941A1 (en) 2009-05-14
MXPA05010385A (es) 2006-03-08
EP1616184A4 (de) 2006-07-12
AU2004225472A1 (en) 2004-10-14
ATE437371T1 (de) 2009-08-15
US20150185231A1 (en) 2015-07-02
ES2754753T3 (es) 2020-04-20
ES2739463T3 (es) 2020-01-31
EP2083270B1 (de) 2019-06-12
EP2360475B1 (de) 2019-10-02
US20040219603A1 (en) 2004-11-04
JP5392980B2 (ja) 2014-01-22
DK2360475T3 (da) 2020-01-06
EP1616184B2 (de) 2018-05-30
US20100227418A1 (en) 2010-09-09
US20100233728A1 (en) 2010-09-16
DK1616184T4 (en) 2018-08-13
BRPI0408802B1 (pt) 2019-08-20
EP2083270A1 (de) 2009-07-29
ES2330005T3 (es) 2009-12-03
JP2011221033A (ja) 2011-11-04
ES2330005T5 (es) 2018-06-20
US20120028371A1 (en) 2012-02-02
BRPI0408802A (pt) 2006-04-04
WO2004088276A3 (en) 2004-11-25
US20130183693A1 (en) 2013-07-18
US20130137116A1 (en) 2013-05-30
US20070254370A1 (en) 2007-11-01
DK1616184T3 (da) 2009-10-19
EP1616184B1 (de) 2009-07-22
EP1616184A2 (de) 2006-01-18
EP2360475A1 (de) 2011-08-24
JP2006521565A (ja) 2006-09-21
CN102183656A (zh) 2011-09-14
BRPI0408802B8 (pt) 2021-07-27
US20130137191A1 (en) 2013-05-30
US20090181407A1 (en) 2009-07-16
CA2520658A1 (en) 2004-10-14
WO2004088276A2 (en) 2004-10-14
NZ543028A (en) 2008-06-30
AU2004225472B2 (en) 2011-02-10
CN102183656B (zh) 2014-04-16

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