DE602004021685D1 - Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld - Google Patents

Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld

Info

Publication number
DE602004021685D1
DE602004021685D1 DE602004021685T DE602004021685T DE602004021685D1 DE 602004021685 D1 DE602004021685 D1 DE 602004021685D1 DE 602004021685 T DE602004021685 T DE 602004021685T DE 602004021685 T DE602004021685 T DE 602004021685T DE 602004021685 D1 DE602004021685 D1 DE 602004021685D1
Authority
DE
Germany
Prior art keywords
flag
biological
chemical substances
free detection
evanescence field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004021685T
Other languages
English (en)
Inventor
Po Ki Yuen
Frederic J Quan
Eric J Mozdy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corning Inc
Original Assignee
Corning Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Inc filed Critical Corning Inc
Publication of DE602004021685D1 publication Critical patent/DE602004021685D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
DE602004021685T 2003-03-27 2004-02-27 Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld Expired - Lifetime DE602004021685D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45811903P 2003-03-27 2003-03-27
PCT/US2004/006046 WO2005012886A1 (en) 2003-03-27 2004-02-27 Label-free evanescent-field detection of biological and chemical agents

Publications (1)

Publication Number Publication Date
DE602004021685D1 true DE602004021685D1 (de) 2009-08-06

Family

ID=34115279

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004021685T Expired - Lifetime DE602004021685D1 (de) 2003-03-27 2004-02-27 Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld

Country Status (5)

Country Link
US (1) US7368281B2 (de)
EP (1) EP1616169B1 (de)
JP (1) JP4751328B2 (de)
DE (1) DE602004021685D1 (de)
WO (1) WO2005012886A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8017174B2 (en) * 2003-05-16 2011-09-13 Board Of Regents The University Of Texas System Densely packed sensor arrays
MXPA06005558A (es) 2003-11-20 2006-12-15 Biowarn Llc Metodologia y aparato para la deteccion de sustancias biologicas.
GB0327755D0 (en) * 2003-12-01 2003-12-31 Elliott Stephen R Optical-sensor chip
US20070159325A1 (en) * 2004-11-16 2007-07-12 Biowam Llc Methodology and Apparatus for the Detection of Biological Substances
US7834320B2 (en) * 2004-12-06 2010-11-16 Bar-Giora Goldberg Remote biological, chemical and explosive detector
US7349080B2 (en) 2004-12-30 2008-03-25 Corning Incorporated Label-independent detection of unpurified analytes
US8349605B1 (en) * 2005-04-12 2013-01-08 Colorado State University Research Foundation Optical analyte sensor
JP5184353B2 (ja) * 2005-07-20 2013-04-17 コーニング インコーポレイテッド ラベルフリーハイスループット生体分子スクリーニングシステム及び方法
US7606592B2 (en) 2005-09-19 2009-10-20 Becker Charles D Waveguide-based wireless distribution system and method of operation
US8158340B2 (en) * 2005-12-28 2012-04-17 Corning Incorporated Methods for detecting conformational changes in bioentities
WO2007082160A2 (en) * 2006-01-06 2007-07-19 Siemens Healthcare Diagnostics Inc. Method for increasing signal intensity in an optical waveguide sensor
US7976217B2 (en) * 2006-09-15 2011-07-12 Corning Incorporated Screening system and method for analyzing a plurality of biosensors
WO2008130737A1 (en) * 2007-03-01 2008-10-30 Ajjer Llc Analysis of beryllium in soils and other samples by fluorescence
WO2008126666A1 (en) * 2007-03-23 2008-10-23 Canon Kabushiki Kaisha Sensing apparatus
JP2010524465A (ja) * 2007-04-19 2010-07-22 コーニング インコーポレイテッド 病原体侵入の生細胞シグナルおよびその方法
WO2009076323A2 (en) * 2007-12-06 2009-06-18 Genalyte Inc. Monitoring enzymatic process
JP5238820B2 (ja) * 2007-12-26 2013-07-17 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロ電子センサデバイス
US8046175B2 (en) * 2008-10-13 2011-10-25 Actherm Inc Analytical strip reading apparatus and the analyical strip used therein
WO2010062627A2 (en) 2008-10-27 2010-06-03 Genalyte Inc. Biosensors based on optical probing and sensing
WO2010063116A1 (en) * 2008-12-02 2010-06-10 National Research Council Of Canada Grating-based evanescent field molecular sensor using a thin silicon waveguide layer
KR101229160B1 (ko) * 2008-12-05 2013-02-01 액텀 아이엔씨. 착탈식 펌웨어를 갖는 시편 판독기
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US8331751B2 (en) * 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
CN102576020B (zh) * 2009-09-28 2014-09-17 皇家飞利浦电子股份有限公司 用于生物性结合的特性描述的方法
EP2616797B1 (de) 2010-09-15 2017-01-11 MBIO Diagnostics Inc. System und verfahren zur detektion von mehreren molekülen in einem assay
US20120070885A1 (en) * 2010-09-21 2012-03-22 Florida State University Research Foundation Integrated device for analyzing aqueous samples using lipid multilayer gratings
EP3266881B1 (de) 2010-11-05 2019-12-25 Genalyte, Inc. Systeme zur optischen analytdetektion und verfahren zur verwendung
EP2734841B1 (de) 2011-07-20 2017-07-05 University Of Washington Through Its Center For Commercialization Photonische blutgruppenbestimmung
US9242248B2 (en) * 2011-09-16 2016-01-26 The University Of North Carolina At Charlotte Methods and devices for optical sorting of microspheres based on their resonant optical properties
US9841367B2 (en) * 2011-09-16 2017-12-12 The University Of North Carolina At Charlotte Methods and devices for optical sorting of microspheres based on their resonant optical properties
US10031138B2 (en) 2012-01-20 2018-07-24 University Of Washington Through Its Center For Commercialization Hierarchical films having ultra low fouling and high recognition element loading properties
EP2743694A1 (de) * 2012-12-14 2014-06-18 Numares GmbH Verfahren zur Ergänzung einer Probe mit spezifischen Informationen und Probenröhrchensystem
US9983206B2 (en) 2013-03-15 2018-05-29 The Board Of Trustees Of The University Of Illinois Methods and compositions for enhancing immunoassays
ES2854352T3 (es) * 2014-03-24 2021-09-21 Instr Laboratory Co Sistema de bioensayo y método para detectar analitos en fluidos corporales
KR101651337B1 (ko) * 2014-06-18 2016-08-25 한국과학기술원 진단용 마이크로 칩 및 이를 이용한 통합형 회전식 병원균 확인 방법
WO2020148566A2 (en) * 2018-08-31 2020-07-23 University Of Montana Apparatus and method for the detection of bioaerosols
WO2023112482A1 (ja) * 2021-12-14 2023-06-22 シスメックス株式会社 細胞外小胞の測定方法、神経変性に関する情報の取得方法、細胞外小胞の単離方法及び試薬キット

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US392275A (en) 1888-11-06 The sliveb in sliver boxes of carding
US4815843A (en) 1985-05-29 1989-03-28 Oerlikon-Buhrle Holding Ag Optical sensor for selective detection of substances and/or for the detection of refractive index changes in gaseous, liquid, solid and porous samples
GB8813307D0 (en) * 1988-06-06 1988-07-13 Amersham Int Plc Biological sensors
GB9212416D0 (en) * 1992-06-11 1992-07-22 Medical Res Council Reversible binding substances
GB9314991D0 (en) 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
EP0888546A1 (de) 1996-03-19 1999-01-07 University Of Utah Research Foundation Oszillator und methoden fur multi-analyt fluoro-immunassays
US5804384A (en) 1996-12-06 1998-09-08 Vysis, Inc. Devices and methods for detecting multiple analytes in samples
WO1999013320A1 (de) 1997-09-10 1999-03-18 Artificial Sensing Instruments Asi Ag Optischer sensor und optisches verfahren zur charakterisierung einer chemischen und/oder biochemischen substanz
US6277628B1 (en) 1998-10-02 2001-08-21 Incyte Genomics, Inc. Linear microarrays
CA2358566A1 (en) * 1999-01-08 2000-07-13 Charles S. Vann Fiber array for contacting chemical species and methods for using and making same
US6192168B1 (en) * 1999-04-09 2001-02-20 The United States Of America As Represented By The Secretary Of The Navy Reflectively coated optical waveguide and fluidics cell integration
EP1266207B1 (de) * 2000-03-22 2010-10-27 Axela Inc. Verfahren und vorrichtung zur bestimmung mehrerer analyten
US7244572B1 (en) 2000-03-24 2007-07-17 Wisys Technology Foundation, Inc. One-dimensional arrays on optical fibers
US7678539B2 (en) 2000-08-10 2010-03-16 Corning Incorporated Arrays of biological membranes and methods and use thereof
US7264973B2 (en) 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7153702B2 (en) 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US6951715B2 (en) 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7175980B2 (en) 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US20030113766A1 (en) 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7101660B2 (en) 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7118710B2 (en) 2000-10-30 2006-10-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US20030092075A1 (en) 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7023544B2 (en) 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7217574B2 (en) 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7306827B2 (en) 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US6777244B2 (en) * 2000-12-06 2004-08-17 Hrl Laboratories, Llc Compact sensor using microcavity structures
JP2002277390A (ja) * 2001-03-22 2002-09-25 Fuji Photo Film Co Ltd 測定チップ
US6841663B2 (en) 2001-10-18 2005-01-11 Agilent Technologies, Inc. Chemical arrays
US7497992B2 (en) 2003-05-08 2009-03-03 Sru Biosystems, Inc. Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers

Also Published As

Publication number Publication date
EP1616169B1 (de) 2009-06-24
US20040191765A1 (en) 2004-09-30
EP1616169A1 (de) 2006-01-18
WO2005012886A1 (en) 2005-02-10
JP4751328B2 (ja) 2011-08-17
JP2007501402A (ja) 2007-01-25
US7368281B2 (en) 2008-05-06

Similar Documents

Publication Publication Date Title
DE602004021685D1 (de) Markierungsfreier nachweis biologischer und chemischer stoffe mittels evaneszenzfeld
DE602004018575D1 (de) Chirurgisches Ultraschallsystem und Probe
DE602004024068D1 (de) Bedingungsanalyseeinrichtung
DE602004009894D1 (de) Chemischer sensor
DK1266608T3 (da) Biologisk væskeprövetagnings- og analytmåleindretning
DE602004031909D1 (de) Ausdruck mittels Zusammenspiel von Bilderzeugungsgeräten
DE502004004192D1 (de) Drehknopf eines bediengerätes
DE60327664D1 (de) Persönliche identifikationseinrichtung
FR2881225B1 (fr) Appareil de detection portable permettant de detecter sur le terrain des elements marques par fluorescence
FI20030261A (fi) Iskulaite
ATE465977T1 (de) Fluidbehandlungseinrichtung
DE602005001290D1 (de) Spektralanalyse mittels Anregung von evaneszenten Feldern
DE602004024147D1 (de) Vorrichtung zur chemischen Analyse
ITRN20030024A0 (it) Dispositivo per il prelievo di campioni biologici e chimici
DE602004004262D1 (de) Ultraschallbehandlung von gewebematrices
DE602004022084D1 (de) Bandgiessen von nicht eisenhaltigen und leichtmetallen und vorrichtung dafür
DE202004015484U1 (de) Probenbearbeitungsvorrichtung und Probenanalysevorrichtung
DE602004026773D1 (de) Verfahrensherstellung von ethern
SE0303177L (sv) Undersökningsmetod och -anordning
FI20031678A0 (fi) Näytteen käsittelymenetelmä ja järjestely siihen
DE602006020224D1 (de) Kleine Vorrichtung zur Analyse von Genen
ITTO20050555A1 (it) Dispositivo e metodo di attuazione
DE602004011292D1 (de) Vorrichtung zur Vokaldetektion
DE50306263D1 (de) Detektion von toxischen algen
DE502004002729D1 (de) Labor-Pumpeinheit

Legal Events

Date Code Title Description
8364 No opposition during term of opposition