DE60138428D1 - Oralen Arzneiform mit Oeffnungen in der äusseren Hülle - Google Patents

Oralen Arzneiform mit Oeffnungen in der äusseren Hülle

Info

Publication number
DE60138428D1
DE60138428D1 DE60138428T DE60138428T DE60138428D1 DE 60138428 D1 DE60138428 D1 DE 60138428D1 DE 60138428 T DE60138428 T DE 60138428T DE 60138428 T DE60138428 T DE 60138428T DE 60138428 D1 DE60138428 D1 DE 60138428D1
Authority
DE
Germany
Prior art keywords
openings
outer shell
core
oral pharmaceutical
pharmaceutical form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60138428T
Other languages
English (en)
Inventor
Luigi Martini
Chi Leung Li
Philip Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Ltd
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd, SmithKline Beecham Corp filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE60138428D1 publication Critical patent/DE60138428D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23B—TURNING; BORING
    • B23B37/00—Boring by making use of ultrasonic energy
DE60138428T 2000-11-08 2001-11-02 Oralen Arzneiform mit Oeffnungen in der äusseren Hülle Expired - Lifetime DE60138428D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0027471.2A GB0027471D0 (en) 2000-11-08 2000-11-08 Processes

Publications (1)

Publication Number Publication Date
DE60138428D1 true DE60138428D1 (de) 2009-05-28

Family

ID=9902924

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60116530T Expired - Lifetime DE60116530T2 (de) 2000-11-08 2001-11-02 Prozess zur herstellung einer oralen arzneiform
DE60138428T Expired - Lifetime DE60138428D1 (de) 2000-11-08 2001-11-02 Oralen Arzneiform mit Oeffnungen in der äusseren Hülle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60116530T Expired - Lifetime DE60116530T2 (de) 2000-11-08 2001-11-02 Prozess zur herstellung einer oralen arzneiform

Country Status (9)

Country Link
US (2) US7923027B2 (de)
EP (2) EP1655024B1 (de)
JP (1) JP4290981B2 (de)
AT (2) ATE428407T1 (de)
AU (1) AU2002218280A1 (de)
DE (2) DE60116530T2 (de)
ES (2) ES2256329T3 (de)
GB (1) GB0027471D0 (de)
WO (1) WO2002038131A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
US20030153607A1 (en) * 1998-11-12 2003-08-14 Smithkline Beecham P.L.C. Novel composition and use
JP2005508325A (ja) * 2001-09-28 2005-03-31 マクニール−ピーピーシー・インコーポレイテッド 内側コア及び外側シェルを有する投薬形態
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
PE20030800A1 (es) * 2002-02-12 2003-10-31 Glaxo Group Ltd Forma de dosificacion oral de liberacion controlada
GB0203296D0 (en) 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
US8637512B2 (en) * 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
KR20050071517A (ko) * 2002-09-28 2005-07-07 맥네일-피피씨, 인코포레이티드 코어를 2개 갖는 개질된 방출성 투여 제형
GB0318824D0 (en) * 2003-08-11 2003-09-10 Glaxo Group Ltd Novel composition
EP1686967A4 (de) * 2003-11-25 2012-08-08 Smithkline Beecham Cork Ltd Carvedilol-freie base, salze, wasserfreie formen oder solvate davon, entsprechende pharmazeutische zusammensetzungen, formulierungen mit kontrollierter freisetzung und behandlungs- oder abgabeverfahren
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
BRPI0520830A2 (pt) * 2005-12-30 2009-05-19 Accu Break Technologies Inc forma de dosagem farmacêutica sólida, método de subdividir uma forma de dosagem farmacêutica sólida, método de administração de uma parte de uma subunidade ativa de uma forma de dosagem farmacêutica sólida, método de administração de um ingrediente farmacêutico ativo que está presente dentro de uma subunidade ativa de uma forma de dosagem farmacêutica sólida e método de produção de uma forma de dosagem farmacêutica sólida
US8273105B2 (en) * 2008-02-20 2012-09-25 Tyco Healthcare Group Lp Compound barb medical device and method
BRPI0822655A2 (pt) * 2008-06-04 2015-06-30 Colgate Palmolive Co Implemento e sistema para cuidado oral
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
MX2011000636A (es) * 2008-07-18 2011-08-03 Valeant Pharmaceuticals Int Formulacion de liberacion modificada y metodos de uso.
JP2022532252A (ja) 2019-05-17 2022-07-13 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド （Ｓ）－５－ベンジル－Ｎ－（５－メチル－４－オキソ－２，３，４，５－テトラヒドロベンゾ［ｂ］［１，４］オキサゼピン－３－イル）－４Ｈ－１，２，４－トリアゾール－３－カルボキサミドを含んでなるマトリックス組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1575050A1 (de) * 1966-01-12 1972-04-13 Misto Gen Equipment Co Ultraschall-Nebelerzeugungsgeraet
US4447235A (en) * 1981-05-07 1984-05-08 John M. Clarke Thoracentesis device
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
EP0303769A3 (de) * 1987-08-18 1989-10-25 Balzers Aktiengesellschaft Vorrichtung zur Übertragung von Drehbewegungen durch die Wand einer Vakuumkammer
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
JPH02124251A (ja) 1988-10-28 1990-05-11 Tanaka Kikinzoku Kogyo Kk 微細穴加工方法
US5123903A (en) * 1989-08-10 1992-06-23 Medical Products Development, Inc. Disposable aspiration sleeve for ultrasonic lipectomy
US5317932A (en) * 1992-02-28 1994-06-07 The Dow Chemical Company Sample probe
US5300046A (en) * 1992-03-30 1994-04-05 Symbiosis Corporation Thoracentesis sheath catheter assembly
US5674235A (en) * 1995-05-10 1997-10-07 Ultralase Technologies International Ultrasonic surgical cutting instrument
JPH1024491A (ja) 1996-07-11 1998-01-27 Seidensha Denshi Kogyo Kk 超音波加工装置
US6783662B2 (en) * 1999-03-18 2004-08-31 Exxonmobil Research And Engineering Company Cavitation enhanced liquid atomization
AU776314B2 (en) * 1999-07-20 2004-09-02 Merck & Co., Inc. Sustained release drug dispersion delivery device
WO2001032149A1 (en) * 1999-10-29 2001-05-10 Merck & Co., Inc. Osmotic controlled release drug delivery device
US7708504B2 (en) * 2005-08-29 2010-05-04 Savannah River Nuclear Solutions, Llc Pneumatic conveyance apparatus and process

Also Published As

Publication number Publication date
JP2004512903A (ja) 2004-04-30
US8765065B2 (en) 2014-07-01
EP1333813B1 (de) 2006-01-04
US20110131754A1 (en) 2011-06-09
DE60116530D1 (de) 2006-03-30
EP1333813A2 (de) 2003-08-13
AU2002218280A1 (en) 2002-05-21
US20040062806A1 (en) 2004-04-01
JP4290981B2 (ja) 2009-07-08
ES2256329T3 (es) 2006-07-16
US7923027B2 (en) 2011-04-12
WO2002038131A2 (en) 2002-05-16
ATE428407T1 (de) 2009-05-15
ATE314839T1 (de) 2006-02-15
GB0027471D0 (en) 2000-12-27
WO2002038131A3 (en) 2002-09-12
DE60116530T2 (de) 2006-08-10
EP1655024B1 (de) 2009-04-15
ES2323879T3 (es) 2009-07-27
EP1655024A1 (de) 2006-05-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition