DE60133538D1 - Formulierung und tabletten mit guaifenesin mit verzögerter freisetzung - Google Patents

Formulierung und tabletten mit guaifenesin mit verzögerter freisetzung

Info

Publication number
DE60133538D1
DE60133538D1 DE60133538T DE60133538T DE60133538D1 DE 60133538 D1 DE60133538 D1 DE 60133538D1 DE 60133538 T DE60133538 T DE 60133538T DE 60133538 T DE60133538 T DE 60133538T DE 60133538 D1 DE60133538 D1 DE 60133538D1
Authority
DE
Germany
Prior art keywords
guaifenesin
product
formulation
release formulation
modified release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60133538T
Other languages
English (en)
Other versions
DE60133538T2 (de
Inventor
Ralph W Blume
Robert D Davis
Donald J Keyser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser LLC
Original Assignee
Adams Respiratory Operations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24233984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60133538(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adams Respiratory Operations Inc filed Critical Adams Respiratory Operations Inc
Publication of DE60133538D1 publication Critical patent/DE60133538D1/de
Application granted granted Critical
Publication of DE60133538T2 publication Critical patent/DE60133538T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
DE60133538T 2000-04-28 2001-04-26 Formulierung und tabletten mit guaifenesin mit verzögerter freisetzung Expired - Lifetime DE60133538T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/559,542 US6372252B1 (en) 2000-04-28 2000-04-28 Guaifenesin sustained release formulation and tablets
US559542 2000-04-28
PCT/US2001/013379 WO2001082895A2 (en) 2000-04-28 2001-04-26 Guaifenesin sustained release formulation and tablets

Publications (2)

Publication Number Publication Date
DE60133538D1 true DE60133538D1 (de) 2008-05-21
DE60133538T2 DE60133538T2 (de) 2009-07-09

Family

ID=24233984

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60133538T Expired - Lifetime DE60133538T2 (de) 2000-04-28 2001-04-26 Formulierung und tabletten mit guaifenesin mit verzögerter freisetzung

Country Status (17)

Country Link
US (1) US6372252B1 (de)
EP (2) EP1276467B1 (de)
JP (1) JP2003531849A (de)
AT (1) ATE391494T1 (de)
AU (2) AU2001255680B2 (de)
CA (1) CA2405031C (de)
CY (1) CY1108166T1 (de)
DE (1) DE60133538T2 (de)
DK (1) DK1276467T3 (de)
ES (1) ES2301537T3 (de)
HK (1) HK1052651A1 (de)
IL (3) IL152012A0 (de)
MX (1) MXPA02010556A (de)
NZ (1) NZ521959A (de)
PT (1) PT1276467E (de)
TW (2) TWI326602B (de)
WO (1) WO2001082895A2 (de)

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JP6184903B2 (ja) * 2014-06-04 2017-08-23 ヴァレアント インターナショナル バミューダＶａｌｅａｎｔ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｂｅｒｍｕｄａ 塩酸ブプロピオン放出調節錠剤
TWI535784B (zh) 2014-08-26 2016-06-01 財團法人工業技術研究院 剪切增稠配方、及包含其之複合材料
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Also Published As

Publication number Publication date
TW200727919A (en) 2007-08-01
EP1276467A2 (de) 2003-01-22
DK1276467T3 (da) 2008-08-04
AU2001255680B2 (en) 2006-02-16
EP1276467B1 (de) 2008-04-09
ATE391494T1 (de) 2008-04-15
AU5568001A (en) 2001-11-12
ES2301537T3 (es) 2008-07-01
CA2405031C (en) 2011-12-06
IL190742A0 (en) 2008-11-03
TWI326602B (en) 2010-07-01
JP2003531849A (ja) 2003-10-28
HK1052651A1 (en) 2003-09-26
EP1913937A1 (de) 2008-04-23
CA2405031A1 (en) 2001-11-08
IL152012A0 (en) 2003-04-10
US6372252B1 (en) 2002-04-16
PT1276467E (pt) 2008-05-15
NZ521959A (en) 2004-10-29
DE60133538T2 (de) 2009-07-09
WO2001082895A2 (en) 2001-11-08
WO2001082895A3 (en) 2002-05-23
MXPA02010556A (es) 2003-10-14
IL152012A (en) 2010-04-15
CY1108166T1 (el) 2014-02-12
TWI314866B (en) 2009-09-21

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