DE60131530D1 - Vorrichtung zum erzeugen eines aerosols - Google Patents

Vorrichtung zum erzeugen eines aerosols

Info

Publication number
DE60131530D1
DE60131530D1 DE60131530T DE60131530T DE60131530D1 DE 60131530 D1 DE60131530 D1 DE 60131530D1 DE 60131530 T DE60131530 T DE 60131530T DE 60131530 T DE60131530 T DE 60131530T DE 60131530 D1 DE60131530 D1 DE 60131530D1
Authority
DE
Germany
Prior art keywords
aerosol
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60131530T
Other languages
English (en)
Other versions
DE60131530T2 (de
Inventor
Peter R Byron
Michael Hindle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philip Morris USA Inc
Original Assignee
Philip Morris USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris USA Inc filed Critical Philip Morris USA Inc
Publication of DE60131530D1 publication Critical patent/DE60131530D1/de
Application granted granted Critical
Publication of DE60131530T2 publication Critical patent/DE60131530T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
    • A61M16/109—Preparation of respiratory gases or vapours by influencing the temperature the humidifying liquid or the beneficial agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
DE60131530T 2000-04-27 2001-04-25 Vorrichtung zum erzeugen eines aerosols Expired - Lifetime DE60131530T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56051000A 2000-04-27 2000-04-27
US560510 2000-04-27
PCT/US2001/040597 WO2001081182A2 (en) 2000-04-27 2001-04-25 Improved method and apparatus for generating an aerosol

Publications (2)

Publication Number Publication Date
DE60131530D1 true DE60131530D1 (de) 2008-01-03
DE60131530T2 DE60131530T2 (de) 2008-10-23

Family

ID=24238095

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60131530T Expired - Lifetime DE60131530T2 (de) 2000-04-27 2001-04-25 Vorrichtung zum erzeugen eines aerosols

Country Status (10)

Country Link
US (1) US7128067B2 (de)
EP (1) EP1276672B1 (de)
JP (1) JP4602631B2 (de)
AR (1) AR028042A1 (de)
AU (2) AU5980401A (de)
CA (1) CA2406042C (de)
DE (1) DE60131530T2 (de)
MY (1) MY136453A (de)
TW (1) TW500614B (de)
WO (1) WO2001081182A2 (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6883516B2 (en) * 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US7077130B2 (en) * 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US7594507B2 (en) * 2001-01-16 2009-09-29 Hewlett-Packard Development Company, L.P. Thermal generation of droplets for aerosol
US7766013B2 (en) * 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7645442B2 (en) * 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7090830B2 (en) * 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US6805853B2 (en) * 2001-11-09 2004-10-19 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US6759029B2 (en) * 2001-05-24 2004-07-06 Alexza Molecular Delivery Corporation Delivery of rizatriptan and zolmitriptan through an inhalation route
US7585493B2 (en) * 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
JP2005503425A (ja) * 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
JP4357842B2 (ja) * 2001-05-24 2009-11-04 アレックザ ファーマシューティカルズ， インコーポレイテッド 所定の吸入ルートによるアルプラゾラム、エスタゾラム、ミダゾラムまたはトリアゾラムの送出
US7458374B2 (en) * 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US6681769B2 (en) * 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
EP1494732B1 (de) 2002-03-20 2008-01-30 MannKind Corporation Inhalationsgerät
EP1503744A1 (de) * 2002-05-13 2005-02-09 Alexza Molecular Delivery Corporation Verabreichung von aminenhaltigen arzneistoffen durch inhalation
US20060193788A1 (en) * 2002-11-26 2006-08-31 Hale Ron L Acute treatment of headache with phenothiazine antipsychotics
ES2357566T3 (es) 2002-09-06 2011-04-27 Philip Morris Usa Inc. Dispositivos generadores de aerosol y métodos para generar aerosoles con tamaños de partículas controlados.
US7040314B2 (en) * 2002-09-06 2006-05-09 Philip Morris Usa Inc. Aerosol generating devices and methods for generating aerosols suitable for forming propellant-free aerosols
CA2507159A1 (en) * 2002-11-26 2004-06-10 Alexza Molecular Delivery Corporation Use of loxapine and amoxapine for the manufacture of a medicament for the treatment of pain
US20040105818A1 (en) * 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
JP2006514633A (ja) * 2002-11-26 2006-05-11 アレックザ ファーマシューティカルズ， インコーポレイテッド 吸入によって送達される抗精神病薬を用いた頭痛の治療
US7550133B2 (en) * 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
US7913688B2 (en) * 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
EP1596824A4 (de) * 2003-02-04 2011-11-23 Chrysalis Tech Inc Aerosolformulierungen und aerosolabgabe von buspiron, buprenorphin, triazolam, zyckobenzaprin und zolpidem
JP4601619B2 (ja) 2003-05-21 2010-12-22 アレックザ ファーマシューティカルズ， インコーポレイテッド 内蔵式加熱ユニットおよびそれを使用する薬剤供給ユニット
WO2004112799A1 (en) * 2003-06-13 2004-12-29 Chrysalis Technologies Incorporated Methods and apparatus for producing nanoscale particles
JP4869927B2 (ja) * 2003-08-04 2012-02-08 アレックザ ファーマシューティカルズ， インコーポレイテッド 薬物送達デバイスのための基材および調製方法および使用
WO2005037949A2 (en) * 2003-10-07 2005-04-28 Chrysalis Technologies Incorporated Aerosol formulations of butalbital, lorazepam, ipratropium, baclofen, morphine and scopolamine
US7347859B2 (en) * 2003-12-18 2008-03-25 Boston Scientific, Scimed, Inc. Tissue treatment system and method for tissue perfusion using feedback control
US20050150489A1 (en) * 2004-01-12 2005-07-14 Steve Dunfield Dispensing medicaments based on rates of medicament action
US7540286B2 (en) * 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
WO2006009176A1 (ja) * 2004-07-20 2006-01-26 Asahi Glass Company, Limited 液晶レンズ素子および光ヘッド装置
US20100006092A1 (en) * 2004-08-12 2010-01-14 Alexza Pharmaceuticals, Inc. Aerosol Drug Delivery Device Incorporating Percussively Activated Heat Packages
EP2246086A3 (de) * 2004-08-12 2012-11-21 Alexza Pharmaceuticals, Inc. Aerosolverabreichungsvorrichtung mit Schlag gezündete Heizeinheit
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
PL2322180T3 (pl) 2004-08-23 2015-10-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
US20060102175A1 (en) * 2004-11-18 2006-05-18 Nelson Stephen G Inhaler
WO2006090260A1 (en) * 2005-02-28 2006-08-31 Pulmonox Technologies Corporation Means and method for supplying therapeutic gas to a spontaneously breathing patient
US7186958B1 (en) * 2005-09-01 2007-03-06 Zhao Wei, Llc Inhaler
CN104324366B (zh) 2005-09-14 2016-10-05 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
CA2623358C (en) * 2005-09-26 2014-09-09 University Of Leeds Fuel injector
US8375987B2 (en) * 2005-12-22 2013-02-19 Donovan B. Yeates Concentrator for increasing the particle concentration in an aerosol flow
US8820662B2 (en) 2005-12-22 2014-09-02 Donovan B. Yeates Nozzle and nozzle holder for an aerosol generator
US7802569B2 (en) * 2005-12-22 2010-09-28 Kaer Biotherapeutics Corporation Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery
US8596268B2 (en) 2005-12-22 2013-12-03 Donovan B. Yeates Method of operating a compact, low flow resistance aerosol generator
US8616532B2 (en) 2005-12-22 2013-12-31 Donovan B. Yeates Flow conditioner for a compact, low flow resistance aerosol generator
MX360812B (es) 2006-02-22 2018-11-16 Mannkind Corp Un método para mejorar las propiedades farmacéuticas de micropartículas que contienen dicetopiperazina y un agente activo.
US20080069780A1 (en) * 2006-04-05 2008-03-20 S.C. Johnson & Son, Inc. High Concentration Single Phase Gycol Aerosol Air Sanitizer with Dimethyl Ether Propellant/Solvent
PT2032266E (pt) * 2006-06-09 2013-03-25 Philip Morris Prod Gerador capilar de aerossóis aquecido indirectamente
WO2008080170A1 (en) * 2006-12-22 2008-07-03 Alexza Pharmaceuticals, Inc. Mixed drug aerosol compositiions
US9061300B2 (en) * 2006-12-29 2015-06-23 Philip Morris Usa Inc. Bent capillary tube aerosol generator
ES2594867T3 (es) 2007-03-09 2016-12-23 Alexza Pharmaceuticals, Inc. Unidad de calentamiento para usar en un dispositivo de administración de fármaco
MX2010003438A (es) * 2007-10-02 2010-04-21 Philip Morris Prod Sistema capilar con elemento fluidico.
US8052127B2 (en) * 2007-10-19 2011-11-08 Philip Morris Usa Inc. Respiratory humidification system
WO2009069518A1 (ja) * 2007-11-29 2009-06-04 Japan Tobacco Inc. エアロゾル吸引システム
UA100398C2 (en) * 2007-12-05 2012-12-25 Джапан Тобакко Инк. Aerosol aspirator
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products
DE202009018480U1 (de) 2008-06-13 2012-01-26 Mannkind Corp. Trockenpulverinhalator und System zur Medikamentenabgabe
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US8495998B2 (en) 2009-06-17 2013-07-30 British American Tobacco (Investments) Limited Inhaler
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
US8422869B2 (en) * 2009-12-16 2013-04-16 Disney Enterprises, Inc. Handheld low-voltage fog effects system
WO2011094684A1 (en) * 2010-02-01 2011-08-04 Geno Llc Nitric oxide delivery system
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
US20120048963A1 (en) 2010-08-26 2012-03-01 Alexza Pharmaceuticals, Inc. Heat Units Using a Solid Fuel Capable of Undergoing an Exothermic Metal Oxidation-Reduction Reaction Propagated without an Igniter
US9301547B2 (en) * 2010-11-19 2016-04-05 Huizhou Kimree Technology Co., Ltd. Shenzhen Branch Electronic cigarette, electronic cigarette smoke capsule and atomization device thereof
BR122020008875B8 (pt) 2011-04-01 2022-12-06 Mannkind Corp Embalagem de bolha e método de fabricação de uma embalagem de bolhas
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9393336B2 (en) * 2011-07-08 2016-07-19 S. C. Johnson & Son, Inc. Insert for dispensing a compressed gas product, system with such an insert, and method of dispensing a compressed gas product
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
US9713687B2 (en) 2012-08-21 2017-07-25 Philip Morris Usa Inc. Ventilator aerosol delivery system with transition adapter for introducing carrier gas
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10034988B2 (en) 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
US10010692B2 (en) * 2013-07-08 2018-07-03 Virginia Commonwealth University Systems, devices, and methods for changing therapeutic aerosol size and improving efficiency of ventilation and aerosol drug delivery
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
WO2015042412A1 (en) 2013-09-20 2015-03-26 E-Nicotine Technology. Inc. Devices and methods for modifying delivery devices
US9802010B2 (en) * 2013-11-22 2017-10-31 Noveome Biotherapeutics, Inc. Interproximal drug delivery device
US10743793B2 (en) * 2014-03-10 2020-08-18 Respimetrix Gmbh Systems and methods for delivering an agent to a user's lungs and for simultaneously monitoring lung health
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
EP3191162B1 (de) 2014-09-10 2022-02-23 Fontem Holdings 1 B.V. Verfahren und vorrichtungen zur modulierung des luftstroms in abgabevorrichtungen
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
RU2681342C2 (ru) * 2015-01-22 2019-03-06 Фонтем Холдингс 1 Б.В. Электронные испарительные устройства
CN107750177B (zh) * 2015-03-11 2022-03-11 艾利斯达医药品公司 气道中的防静电材料用于热气溶胶凝结方法的用途
EP3097803A1 (de) * 2015-05-26 2016-11-30 Fontem Holdings 1 B.V. Elektronische rauchvorrichtung
US11425911B2 (en) 2017-05-25 2022-08-30 Markesbery Blue Pearl LLC Method for disinfection of items and spaces
US9861102B2 (en) 2016-05-26 2018-01-09 Markesbery Blue Pearl LLC Methods for disinfection
CA3039029C (en) * 2016-10-12 2021-09-21 Japan Tobacco Inc. Flavor inhaler
BR112020010486A2 (pt) * 2017-12-07 2020-10-20 Philip Morris Products S.A. artigo gerador de aerossol com elemento de centramento expansível de calor
CN109004167B (zh) * 2018-06-15 2023-12-01 宁德时代新能源科技股份有限公司 电池模组
EP3953060A4 (de) * 2019-04-10 2022-12-28 New Mexico Tech University Research Park Corporation Festkörperaerosolgenerator
CN113100494B (zh) * 2020-01-13 2023-02-03 小卫（上海）生物科技有限公司 一种雾化器
CN116818971B (zh) * 2023-06-06 2024-04-05 苏州智爱环境科技有限公司 一种在线有机气溶胶热脱附气相色谱质谱分析系统和方法

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2896856A (en) 1956-12-21 1959-07-28 Licencia Talalmanyokat Vaporizer for diesel engines
US3084698A (en) 1960-04-01 1963-04-09 Marvin M Smith Instrument for cooling smoke
US3162324A (en) 1961-11-22 1964-12-22 Robertshaw Controls Co Pneumatic dispenser
NL297349A (de) 1962-08-31
US3200535A (en) 1963-09-10 1965-08-17 George D Besler Apparatus for creating aerosol dispersions
US3431393A (en) 1965-09-07 1969-03-04 Dainippon Jochugiku Kk Apparatus for vaporizing chemicals and perfumes by heating
US3486663A (en) 1967-11-16 1969-12-30 Frederick Harold Humphrey Elastomeric pump and check-valve
DE1813993C3 (de) 1968-12-11 1974-01-24 Paul Ritzau Pari-Werk Kg, 8135 Soecking Vorrichtung zum Zerstäuben und Vernebeln von flüssigen oder pulverförmigen Stoffen
US3731876A (en) 1971-03-19 1973-05-08 M Showalter Injection spray systems
US3750961A (en) 1971-07-16 1973-08-07 N Franz Very high velocity fluid jet nozzles and methods of making same
US3859398A (en) 1972-10-05 1975-01-07 Hudson Oxygen Therapy Sales Co Outboard heating device
US3902635A (en) 1973-03-05 1975-09-02 Walter J Jinotti Fluid dispensing apparatus
US4042153A (en) 1973-03-14 1977-08-16 Standard Oil Company Liquid dropping device
US3847304A (en) 1973-08-13 1974-11-12 M Cohen Bag-type fluid and paste dispenser
US3967001A (en) 1973-11-01 1976-06-29 The United States Of America As Represented By The Secretary Of The Army Process of preparing a secondary electron emissive coating on the interior walls of a microchannel plate
US3987941A (en) 1973-12-14 1976-10-26 Blessing Alfred V Preserving container for liquid food substances
US3903883A (en) 1974-04-17 1975-09-09 Respiratory Care Variable aerosol heater with automatic temperature control
US3904083A (en) 1974-04-19 1975-09-09 Gen Electric Self-sealing viscous material dispenser loading apparatus
US3995371A (en) 1974-10-10 1976-12-07 The Curators Of The University Of Missouri Electroless plating method for treating teeth
US4077542A (en) 1974-12-02 1978-03-07 Petterson Tor H Unattended aerosol dispenser
US3993246A (en) 1975-06-19 1976-11-23 Erb Elisha Nebulizer and method
US4060082A (en) 1976-08-16 1977-11-29 Mpl, Inc. Dual-ingredient medication dispenser
US4161281A (en) 1976-08-30 1979-07-17 Erb Elisha Pneumatic nebulizer and method
NL165639C (nl) 1977-03-02 1981-05-15 Evert Jacob Sybren Bron Pijp voor sigaretten, sigaren en andere tabaksartikelen waarbij in het rookkanaal een gloeidraad als nabrander is aangebracht.
US4162501A (en) 1977-08-08 1979-07-24 Silonics, Inc. Ink supply system for an ink jet printer
US4258073A (en) 1978-03-02 1981-03-24 Payne John M Taking of finger prints
US4231492A (en) 1978-03-14 1980-11-04 Oatey Co. Apparatus and method for dispensing putty-like material
US4261356A (en) 1978-10-23 1981-04-14 Baxter Travenol Laboratories, Inc. Method and apparatus for controlling the dispensing of fluid
US4289003A (en) 1979-05-10 1981-09-15 Yang Tayhugh L Key holder
GB2050303B (en) 1979-05-21 1983-03-02 Rhen Beteiligung Finanz Dispensing valve
US4291838A (en) 1979-12-26 1981-09-29 C. R. Bard, Inc. Nebulizer and associated heater
US4471892A (en) 1980-02-11 1984-09-18 Fabricated Metals, Inc. Material container having a flexible follower
US4259409A (en) 1980-03-06 1981-03-31 Ses, Incorporated Electroless plating process for glass or ceramic bodies and product
US4303083A (en) * 1980-10-10 1981-12-01 Burruss Jr Robert P Device for evaporation and inhalation of volatile compounds and medications
US4383171A (en) 1980-11-17 1983-05-10 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Particle analyzing method and apparatus
US4391308A (en) 1981-04-16 1983-07-05 Steiner Corporation Soap dispensing system
US4395303A (en) 1981-04-22 1983-07-26 Masco Corporation Method of manufacturing thin-walled corrosion resistant metallic objects
GR79615B (de) 1982-10-08 1984-10-31 Glaxo Group Ltd
US4512341A (en) 1982-11-22 1985-04-23 Lester Victor E Nebulizer with capillary feed
US4682010A (en) 1983-03-07 1987-07-21 Safeway Products, Inc. In-line electric heater for an aerosol delivery system
US4730111A (en) 1983-08-30 1988-03-08 Research Corporation Ion vapor source for mass spectrometry of liquids
US4649911A (en) 1983-09-08 1987-03-17 Baylor College Of Medicine Small particle aerosol generator for treatment of respiratory disease including the lungs
US4575609A (en) 1984-03-06 1986-03-11 The United States Of America As Represented By The United States Department Of Energy Concentric micro-nebulizer for direct sample insertion
IT1196142B (it) 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
US4762995A (en) 1984-06-22 1988-08-09 Georgia Tech Research Corporation Monodisperse aerosol generator
EP0181092B1 (de) 1984-10-04 1993-01-13 I J & L A TETLEY MANUFACTURING PTY LTD Gerät zur Erzeugung eines Gasgemisches für diagnostische Zwecke
US4744932A (en) 1985-05-31 1988-05-17 Celanese Corporation Process for forming a skinless hollow fiber of a cellulose ester
US4700657A (en) 1985-07-10 1987-10-20 Print-Lock Corporation Fingerprinting system incorporating a spray container and a portable vapor tank
CH672600A5 (de) 1985-07-30 1989-12-15 Glaxo Group Ltd
US5133343A (en) 1985-08-09 1992-07-28 Johnson Iv John J Apparatus for supporting an inhaler
JPS62153370A (ja) 1985-12-27 1987-07-08 Alpha Giken:Kk ２―シアノアクリレート系組成物および接着剤
US4837260A (en) 1986-05-23 1989-06-06 Toagosei Chemical Industry Co., Ltd. Cyanoacrylate compositions
US4790305A (en) 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
US4926852B1 (en) 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
US4776515A (en) 1986-08-08 1988-10-11 Froughieh Michalchik Electrodynamic aerosol generator
DE3627222A1 (de) 1986-08-11 1988-02-18 Siemens Ag Ultraschall-taschenzerstaeubergeraet
US4735217A (en) 1986-08-21 1988-04-05 The Procter & Gamble Company Dosing device to provide vaporized medicament to the lungs as a fine aerosol
US4819834A (en) 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
GB8713645D0 (en) 1987-06-11 1987-07-15 Imp Tobacco Ltd Smoking device
US5322057A (en) 1987-07-08 1994-06-21 Vortran Medical Technology, Inc. Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use
US4871115A (en) 1987-08-24 1989-10-03 Hessey B Russell Smoke generating apparatus
US4935624A (en) 1987-09-30 1990-06-19 Cornell Research Foundation, Inc. Thermal-assisted electrospray interface (TAESI) for LC/MS
US4819625A (en) 1987-11-12 1989-04-11 Cimco, Inc. Nebulizer heater
US5063921A (en) 1987-11-12 1991-11-12 Cimco, Inc. Nebulizer heater
US5259370A (en) 1987-11-12 1993-11-09 Cimco, Inc. Nebulizer heater
CH675216A5 (de) 1987-11-30 1990-09-14 Alphasem Ag
US4911157A (en) 1988-01-07 1990-03-27 Pegasus Research Corporation Self-regulating, heated nebulizer system
US5021802A (en) 1988-02-19 1991-06-04 Dataproducts Corporation Thermally reversible sol-gel phase change ink or bubble jet ink
US4871623A (en) 1988-02-19 1989-10-03 Minnesota Mining And Manufacturing Company Sheet-member containing a plurality of elongated enclosed electrodeposited channels and method
US4922901A (en) * 1988-09-08 1990-05-08 R. J. Reynolds Tobacco Company Drug delivery articles utilizing electrical energy
US4947875A (en) 1988-09-08 1990-08-14 R. J. Reynolds Tobacco Company Flavor delivery articles utilizing electrical energy
US4992206A (en) 1988-11-01 1991-02-12 Lowndes Engineering Co., Inc. Aerosol generator apparatus and method of use
EP0373237A1 (de) 1988-12-13 1990-06-20 Siemens Aktiengesellschaft Inhalationsgerät, insbesondere Taschen-Inhalationsgerät
DE3908161A1 (de) 1989-03-13 1990-09-27 Bat Cigarettenfab Gmbh Rauchbarer artikel
US4982097A (en) 1989-05-19 1991-01-01 Battelle Memorial Institute Vaporization device for continuous introduction of liquids into a mass spectrometer
US4941483A (en) 1989-09-18 1990-07-17 R. J. Reynolds Tobacco Company Aerosol delivery article
US5007419A (en) * 1989-09-25 1991-04-16 Allan Weinstein Inhaler device
US5226441A (en) 1989-11-13 1993-07-13 Cmb Industries Backflow preventor with adjustable outflow direction
US5060671A (en) 1989-12-01 1991-10-29 Philip Morris Incorporated Flavor generating article
US5144962A (en) 1989-12-01 1992-09-08 Philip Morris Incorporated Flavor-delivery article
US5056511A (en) 1989-12-14 1991-10-15 Juergen L. Fischer Method and apparatus for compressing, atomizing, and spraying liquid substances
US5231983A (en) 1990-01-03 1993-08-03 Minnesota Mining And Manufacturing Method of and apparatus for the aerosol administration of medication
US5044565A (en) 1990-03-13 1991-09-03 The Board Of Regents Of The University Of Nebrasaka Forming fine particles
US5096092A (en) 1990-03-13 1992-03-17 Mmm, Ltd. Food dispensing apparatus utilizing inflatable bladder
DE4012849A1 (de) 1990-04-23 1991-10-24 Alfill Getraenketechnik Vorrichtung zum fuellen von behaeltern mit einer fluessigkeit
BE1004267A3 (nl) 1990-05-18 1992-10-20 Aurinco Holdings Ltd Zelfdragende spiegel en werkwijze ter vervaardiging daarvan.
DE59103399D1 (de) 1990-06-21 1994-12-08 Wilhelm A Keller Austragkartusche mit Vorratszylinder und Förderkolben.
FR2667254B1 (fr) 1990-09-27 1992-10-30 Commissariat Energie Atomique Nebuliseur pneumatique.
US5217004A (en) 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
US5505214A (en) * 1991-03-11 1996-04-09 Philip Morris Incorporated Electrical smoking article and method for making same
CA2065724A1 (en) * 1991-05-01 1992-11-02 Thomas R. Anthony Method of producing articles by chemical vapor deposition and the support mandrels used therein
US5230445A (en) 1991-09-30 1993-07-27 City Of Hope Micro delivery valve
JP2902197B2 (ja) 1992-02-04 1999-06-07 株式会社日立製作所 大気圧イオン化質量分析装置
BR9307141A (pt) * 1992-09-29 1999-03-30 Inhale Therapeutic Syst Processo para a liberação sistência pulsátil de um fragmento ativo de hormônio de paratiróide (PTH) para um hospedeiro mamífero e para um paciente e composição farmacêutica
US5349946A (en) 1992-10-07 1994-09-27 Mccomb R Carter Microprocessor controlled flow regulated molecular humidifier
US5299565A (en) 1992-10-19 1994-04-05 Brown James N Portable nebulizer apparatus
US5327915A (en) 1992-11-13 1994-07-12 Brown & Williamson Tobacco Corp. Smoking article
US5342180A (en) 1992-11-17 1994-08-30 Ivac Corporation Pump mechanism having a drive motor with an external rotor
US5819726A (en) * 1993-01-29 1998-10-13 Aradigm Corporation Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5395445A (en) 1993-05-20 1995-03-07 Bohanan; Arthur M. Method and apparatus for detecting fingerprints on skin
US5744557A (en) * 1993-06-16 1998-04-28 Minnesota Mining And Manufacturing Company Energy-curable cyanate/ethylenically unsaturated compositions
US5342645A (en) 1993-09-15 1994-08-30 Minnesota Mining And Manufacturing Company Metal complex/cyanoacrylate compositions useful in latent fingerprint development
US5421489A (en) 1994-01-12 1995-06-06 Steiner Company, Inc. Push-type soap dispenser
US5509557A (en) 1994-01-24 1996-04-23 International Business Machines Corporation Depositing a conductive metal onto a substrate
DE4414708A1 (de) * 1994-04-27 1995-11-02 Henkel Ecolab Gmbh & Co Ohg Verfahren und Vorrichtung zum Entleeren eines mit einer thixotropen Paste gefüllten Behälters
ES2245780T3 (es) * 1994-05-18 2006-01-16 Nektar Therapeutics Metodos y composiciones para la formulacion de interferones como un polvo seco.
US5462597A (en) 1994-06-30 1995-10-31 Minnesota Mining And Manufacturing System for inkless fingerprinting
US5509404A (en) * 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
JP3420359B2 (ja) * 1994-10-21 2003-06-23 ダイセル化学工業株式会社 たばこ煙用フィルター素材、繊維状セルロースエステル及びその製造方法
DE4446891A1 (de) * 1994-12-27 1996-07-04 Falk Pharma Gmbh Stabile wäßrige Budesonid-Lösung
DE19510690A1 (de) * 1995-03-14 1996-09-19 Schering Ag Polymere Nano- und/oder Mikropartikel, Verfahren zu deren Herstellung, sowie Verwendung in medizinischen Diagnostik und Therapie
US6014970A (en) * 1998-06-11 2000-01-18 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US6205999B1 (en) * 1995-04-05 2001-03-27 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US6085740A (en) * 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US5474059A (en) 1995-04-08 1995-12-12 Cooper; Guy F. Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
US6136346A (en) * 1995-04-14 2000-10-24 Inhale Therapeutic Systems Powdered pharmaceutical formulations having improved dispersibility
GB9508691D0 (en) * 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US5587582A (en) * 1995-05-19 1996-12-24 Cornell Research Foundation, Inc. Self-aligning liquid junction
WO1997002856A1 (fr) * 1995-07-10 1997-01-30 A & D Company, Limited Atomiseur pratique
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
US5617844A (en) * 1995-09-21 1997-04-08 King; Russell W. Aerosol medication delivery system
US6187214B1 (en) * 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6189803B1 (en) * 1996-05-13 2001-02-20 University Of Seville Fuel injection nozzle and method of use
US6116516A (en) * 1996-05-13 2000-09-12 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
ES2140998B1 (es) * 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
US5743251A (en) * 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
US5958378A (en) * 1996-07-03 1999-09-28 Research Development Foundation High dose liposomal aerosol formulations containing cyclosporin A or budesonide
DE19641750A1 (de) * 1996-10-10 1998-04-23 Henkel Ecolab Gmbh & Co Ohg Topf mit flexiblem Vorratsgebinde und Folgeplatte
US5878752A (en) * 1996-11-25 1999-03-09 Philip Morris Incorporated Method and apparatus for using, cleaning, and maintaining electrical heat sources and lighters useful in smoking systems and other apparatuses
JP2001507701A (ja) * 1996-12-31 2001-06-12 インヘイル・セラピューティック・システムズ・インコーポレーテッド 親水性賦形剤を有する疎水性薬剤の溶液を噴霧乾燥するための方法及びその方法によって作製された組成物
US6192882B1 (en) * 1997-02-24 2001-02-27 Aradigm Corporation Formulation and devices for monitoring the efficacy of the delivery of aerosols
US5756995A (en) * 1997-07-09 1998-05-26 The United States Of America As Represented By The Secretary Of The Army Ion interface for mass spectrometer
US6182712B1 (en) * 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
JP3643224B2 (ja) * 1997-11-25 2005-04-27 日本特殊陶業株式会社 センサ素子電極形成方法
US6054032A (en) * 1998-01-27 2000-04-25 3M Innovative Properties Company Capillary electrophoresis array
US6223746B1 (en) * 1998-02-12 2001-05-01 Iep Pharmaceutical Devices Inc. Metered dose inhaler pump
US6234167B1 (en) * 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6070575A (en) * 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure
US6053176A (en) * 1999-02-23 2000-04-25 Philip Morris Incorporated Heater and method for efficiently generating an aerosol from an indexing substrate
US6235177B1 (en) * 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets

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AU5980401A (en) 2001-11-07
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MY136453A (en) 2008-10-31
CA2406042A1 (en) 2001-11-01
EP1276672A2 (de) 2003-01-22
TW500614B (en) 2002-09-01
WO2001081182A2 (en) 2001-11-01
EP1276672A4 (de) 2003-10-22
CA2406042C (en) 2008-04-22
JP4602631B2 (ja) 2010-12-22
US7128067B2 (en) 2006-10-31
DE60131530T2 (de) 2008-10-23
AU2001259804B2 (en) 2006-12-21
EP1276672B1 (de) 2007-11-21
US20040016427A1 (en) 2004-01-29
AR028042A1 (es) 2003-04-23

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