DE60128900D1 - Massenmarker - Google Patents

Massenmarker

Info

Publication number
DE60128900D1
DE60128900D1 DE60128900T DE60128900T DE60128900D1 DE 60128900 D1 DE60128900 D1 DE 60128900D1 DE 60128900 T DE60128900 T DE 60128900T DE 60128900 T DE60128900 T DE 60128900T DE 60128900 D1 DE60128900 D1 DE 60128900D1
Authority
DE
Germany
Prior art keywords
mass
label
labels
group
different
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128900T
Other languages
English (en)
Other versions
DE60128900T2 (de
Inventor
Gunter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Electrophoretics Ltd
Original Assignee
Electrophoretics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9887608&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60128900(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Electrophoretics Ltd filed Critical Electrophoretics Ltd
Application granted granted Critical
Publication of DE60128900D1 publication Critical patent/DE60128900D1/de
Publication of DE60128900T2 publication Critical patent/DE60128900T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6872Methods for sequencing involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/13Tracers or tags
DE60128900T 2000-03-14 2001-03-14 Massenmarker Expired - Lifetime DE60128900T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0006141 2000-03-14
GBGB0006141.6A GB0006141D0 (en) 2000-03-14 2000-03-14 Mass labels
PCT/GB2001/001122 WO2001068664A2 (en) 2000-03-14 2001-03-14 Mass labels

Publications (2)

Publication Number Publication Date
DE60128900D1 true DE60128900D1 (de) 2007-07-26
DE60128900T2 DE60128900T2 (de) 2008-02-07

Family

ID=9887608

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128900T Expired - Lifetime DE60128900T2 (de) 2000-03-14 2001-03-14 Massenmarker

Country Status (15)

Country Link
US (3) US7294456B2 (de)
EP (2) EP1806586B1 (de)
JP (1) JP4608171B2 (de)
CN (2) CN102839213A (de)
AT (1) ATE364841T1 (de)
AU (2) AU2001240834B2 (de)
CA (1) CA2403114C (de)
DE (1) DE60128900T2 (de)
DK (1) DK1275004T3 (de)
ES (2) ES2389510T3 (de)
GB (1) GB0006141D0 (de)
IL (2) IL151732A0 (de)
NO (1) NO330733B1 (de)
PT (1) PT1275004E (de)
WO (1) WO2001068664A2 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002728A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Characterising nucleic acids
AU8356201A (en) * 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
ATE483161T1 (de) * 2001-04-03 2010-10-15 Thermo Finnigan Llc Zur vereinfachung komplexer peptidgemische geeignete verfahren und kits
DE60223696T2 (de) 2001-09-14 2009-01-29 Electrophoretics Ltd., Cobham Massenmarker
AU2002365271B2 (en) * 2001-11-06 2008-12-11 Agilix Corporation Sensitive coded detection systems
DE60231845D1 (de) * 2001-12-11 2009-05-14 Univ New Jersey Med Diagnoseverfahren für proteinprofilierung
AU2003224253A1 (en) 2002-04-04 2003-10-27 Electrophoretics Limited Method for characterising analytes
EP1588145B1 (de) 2003-01-30 2011-07-06 Life Technologies Corporation Verfahren, mixturen, kits und zusammensetzungen bezüglich der analytbestimmung
GB0306756D0 (en) * 2003-03-24 2003-04-30 Xzillion Gmbh & Co Kg Mass labels
US20060263886A1 (en) * 2003-11-14 2006-11-23 Eric Peters Fluorous labeling for selective processing of biologically-derived samples
US20050148087A1 (en) 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom
US20050148771A1 (en) 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
US7355045B2 (en) 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
WO2005085869A2 (en) * 2004-03-01 2005-09-15 Applera Corporation Determination of analyte characteristics based upon binding properties
WO2005101017A1 (en) * 2004-04-07 2005-10-27 Genentech, Inc. Mass spectrometry of antibody conjugates
CA2567459A1 (en) * 2004-05-19 2005-12-01 Applera Corporation Expression quantification using mass spectrometry
US20070054345A1 (en) * 2004-05-19 2007-03-08 Hunter Christie L Expression quantification using mass spectrometry
US20080206737A1 (en) * 2004-05-19 2008-08-28 Hunter Christie L Expression quantification using mass spectrometry
EP1756307A1 (de) 2004-05-20 2007-02-28 Trillion Genomics Limited Verwendung massenmarkierter sonden zum nachweis von zielnukleinsäuren mittels massenspektrometrie
US20070048752A1 (en) * 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
WO2006017208A1 (en) * 2004-07-12 2006-02-16 Applera Corporation Mass tags for quantitative analyses
CA2575675A1 (en) 2004-07-30 2006-03-09 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
JP2008529035A (ja) * 2005-02-03 2008-07-31 パーキンエルマー エルエーエス,インク. 多次元シグナルを用いる超高感度検出システム
US20070037286A1 (en) * 2005-02-09 2007-02-15 Subhasish Purkayastha Thyroxine-containing compound analysis methods
US20060183238A1 (en) * 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
JP4651094B2 (ja) * 2005-08-09 2011-03-16 キヤノン株式会社 標識されたプローブ結合物体、その製造方法、及びその利用方法
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
WO2007078229A1 (en) * 2006-01-05 2007-07-12 Ge Healthcare Bio-Sciences Ab Kit and method for mass labelling
US7902345B2 (en) * 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US8133701B2 (en) * 2006-12-05 2012-03-13 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US7728287B2 (en) * 2007-03-01 2010-06-01 Lawrence Livermore National Security, Llc Imaging mass spectrometer with mass tags
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
GB0809488D0 (en) 2008-05-23 2008-07-02 Electrophoretics Ltd Mass spectrometric analysis
GB0811574D0 (en) * 2008-06-24 2008-07-30 Trillion Genomics Ltd Characterising planar samples by mass spectrometry
EP2356259A4 (de) * 2008-10-30 2012-11-14 Sequenom Inc Produkte und verfahren zur multiplex-identifizierung von nukleinsäuren
EP2406634A4 (de) 2009-03-10 2013-06-19 Univ Maryland Isobare deuterium-markierungsreagenzien für quantitative analyse
GB0916881D0 (en) * 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
GB0921665D0 (en) 2009-12-10 2010-01-27 Trillion Genomics Ltd Phobes
US8309359B2 (en) 2010-01-15 2012-11-13 California Institute Of Technology Isobaric tags for analyte detection and quantification
US8372653B2 (en) * 2010-01-22 2013-02-12 Dh Technologies Development Pte. Ltd. Mass tag reagents for simultaneous quantitation and identification of small molecules
ES2676183T3 (es) 2010-07-02 2018-07-17 Ventana Medical Systems, Inc. Detección de dianas usando marcas de masa y espectrometría de masas
US8461987B2 (en) * 2010-11-17 2013-06-11 Theodosios Kountotsis System and method for performing chemical analysis of fingerprints for providing at least one response
WO2012159089A1 (en) * 2011-05-19 2012-11-22 Sequenom, Inc. Products and processes for multiplex nucleic acid identification
US9388132B2 (en) 2011-09-15 2016-07-12 Wisconsin Alumni Research Foundation Isobaric tandem mass tags for quantitative proteomics and peptidomics
WO2013170067A1 (en) 2012-05-10 2013-11-14 Thermo Finnigan Llc Method for highly multiplexed quantitation of peptides by mass spectrometry and labeling reagent sets therefor
US9366678B2 (en) 2012-10-25 2016-06-14 Wisconsin Alumni Research Foundation Neutron encoded mass tags for analyte quantification
CN105102977A (zh) * 2012-12-26 2015-11-25 奎斯特诊断投资公司 通过质谱法的c肽检测
JP5569761B1 (ja) * 2013-03-29 2014-08-13 シャープ株式会社 分析方法
GB201308765D0 (en) * 2013-05-15 2013-06-26 Electrophoretics Ltd Mass Tag Reagents
GB201322567D0 (en) 2013-12-19 2014-02-05 Electrophoretics Ltd Mass labels
GB201410523D0 (en) 2014-06-12 2014-07-30 Electrophoretics Ltd Mass labels
AU2016250849A1 (en) 2015-04-24 2017-11-02 Agena Bioscience, Inc. Multiplex methods for detection and quantification of minor variants
US10233489B2 (en) 2015-04-24 2019-03-19 Agena Bioscience, Inc. Multiplexed method for the identification and quantitation of minor alleles and polymorphisms
GB201511508D0 (en) * 2015-07-01 2015-08-12 Ge Healthcare Bio Sciences Ab Method for determining a size of biomolecules
GB201521919D0 (en) 2015-12-11 2016-01-27 Electrophoretics Ltd Isobaric mass labels
GB201521903D0 (en) 2015-12-11 2016-01-27 Electrophoretics Ltd Isorbaric mass labels
CN108700551B (zh) * 2016-02-22 2021-12-03 株式会社岛津制作所 唾液酸糖链解析方法
JP7051871B2 (ja) * 2016-12-23 2022-04-11 エフ.ホフマン-ラ ロシュ アーゲー 分析系におけるプロセス中に試薬を同定するための方法
JP7046070B2 (ja) * 2016-12-23 2022-04-01 エフ.ホフマン-ラ ロシュ アーゲー 分析系におけるプロセス中に試薬を同定するための方法
WO2018115243A1 (en) * 2016-12-23 2018-06-28 Roche Diagnostics Gmbh Method for tracking a sample identity during a process in an analysis system
JP2022526128A (ja) * 2019-03-21 2022-05-23 シー2センス, インコーポレイテッド 揮発性イオンの検出のためのシステムおよび関連する方法
GB201907792D0 (en) 2019-05-31 2019-07-17 Thermo Fisher Scient Bremen Gmbh Deconvolution of mass spectromerty data
EP4047371A1 (de) 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Verfahren und vorrichtung zur analyse von proben von biomolekülen mittels massenspektrometrie mit datenunabhängiger erfassung

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5252296A (en) 1990-05-15 1993-10-12 Chiron Corporation Method and apparatus for biopolymer synthesis
GB9315847D0 (en) 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
JPH08145948A (ja) * 1994-11-16 1996-06-07 Sumitomo Chem Co Ltd 還元性オリゴ糖の質量分析法
US6027890A (en) * 1996-01-23 2000-02-22 Rapigene, Inc. Methods and compositions for enhancing sensitivity in the analysis of biological-based assays
ES2144846T5 (es) 1996-01-23 2006-07-16 Qiagen Genomics, Inc. Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos.
AU2217597A (en) * 1996-03-18 1997-10-22 Sequenom, Inc. Dna sequencing by mass spectrometry
EP0863858B1 (de) 1996-04-08 2004-02-04 Glaxo Group Limited Auf masse basierte kodierung und qualitative analyse von kombinatorischen bibliotheken
GB9620769D0 (en) 1996-10-04 1996-11-20 Brax Genomics Ltd Nucleic acid sequencing
JPH10123096A (ja) * 1996-10-22 1998-05-15 Sumitomo Chem Co Ltd シアロオリゴ糖の質量分析法
DE69735445T2 (de) 1996-12-10 2006-08-10 Sequenom, Inc., San Diego Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
DE69838519T2 (de) * 1997-01-15 2008-07-03 Xzillion Gmbh & Co. Kg Massenmarkierte Hybridisierungssonden
WO1999002728A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Characterising nucleic acids
GB9718921D0 (en) 1997-09-05 1997-11-12 Brax Genomics Ltd Catalytically generated mass labels
CA2303790A1 (en) 1997-09-15 1999-03-25 Brax Group Limited Characterising nucleic acid by mass spectrometry
FI106679B (fi) * 1997-12-16 2001-03-15 Nokia Networks Oy Optinen vastaanotin
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB9823646D0 (en) * 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry
AU8356201A (en) 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
US9722639B2 (en) 2013-05-01 2017-08-01 Qorvo Us, Inc. Carrier aggregation arrangements for mobile devices
US9701046B2 (en) 2013-06-21 2017-07-11 Pavestone, LLC Method and apparatus for dry cast facing concrete deposition
US9187086B1 (en) 2014-05-22 2015-11-17 Ford Global Technologies, Llc Clutch control to enter powersplit hybrid powertrain parallel mode
US9701070B2 (en) 2014-11-06 2017-07-11 Lockheed Martin Corporation Mandrel forming for discrete wing skin stiffeners

Also Published As

Publication number Publication date
US7294456B2 (en) 2007-11-13
CA2403114C (en) 2007-07-31
CN1427953A (zh) 2003-07-02
US20080167197A1 (en) 2008-07-10
CA2403114A1 (en) 2001-09-20
IL151732A0 (en) 2003-04-10
PT1275004E (pt) 2007-08-14
AU2001240834B2 (en) 2005-11-17
IL151732A (en) 2008-11-03
US20080145850A1 (en) 2008-06-19
NO20024344D0 (no) 2002-09-12
DE60128900T2 (de) 2008-02-07
DK1275004T3 (da) 2007-10-15
ES2287104T3 (es) 2007-12-16
JP4608171B2 (ja) 2011-01-05
NO330733B1 (no) 2011-06-27
US20030194717A1 (en) 2003-10-16
JP2003529059A (ja) 2003-09-30
WO2001068664A2 (en) 2001-09-20
AU4083401A (en) 2001-09-24
US7816304B2 (en) 2010-10-19
ES2389510T3 (es) 2012-10-26
CN1427953B (zh) 2012-08-29
ATE364841T1 (de) 2007-07-15
US7825069B2 (en) 2010-11-02
NO20024344L (no) 2002-11-14
WO2001068664A3 (en) 2002-03-21
EP1275004B1 (de) 2007-06-13
EP1275004A2 (de) 2003-01-15
EP1806586A1 (de) 2007-07-11
CN102839213A (zh) 2012-12-26
EP1806586B1 (de) 2012-08-15
GB0006141D0 (en) 2000-05-03

Similar Documents

Publication Publication Date Title
DE60128900D1 (de) Massenmarker
CA2460131A1 (en) Mass labels
ATE537451T1 (de) Massenmarkierungen
DE60327649D1 (de) Markierte nukleotide
DE59812124D1 (de) Thermisch härtbare, wässrige zusammensetzungen
HK1054241A1 (en) Polymer matrix electroluminescent materials and devices
RS51229B (sr) Bezbednosni element koji sadrži aspekt koji zavisi od ugla posmatranja
NO20020348D0 (no) Peptid acceptor ligeringsmetoder
DE60109563D1 (de) Zusammensetzung auf der Basis von Olefinharzen
ATE312866T1 (de) Antivirale dendrimere
DE60238156D1 (de) Auf zwei Weisen härtbare Siliconzusammensetzungen
EP1709699B8 (de) Konjugierte polymere, deren darstellung und verwendung
FR2792443B1 (fr) Actionneurs telecommandes par des emetteurs possedant un numero d'identite
HK1036290A1 (en) Modified polycyclic polymers
GT200200038A (es) Conjugados peg de hgf-nk4
AR019961A1 (es) Marcador magnetico de pagina.
BR0114972A (pt) Marcadores moleculares para sistemas de solventes orgânicos
HN1998000045A (es) Composiciones farmaceuticas
EP1303598A4 (de) Molekulare marker
ATE430170T1 (de) Hochschlagfeste aromatische monovinylidenpolymere
DE60003174D1 (de) Harzzusammensetzung auf wasser basis
AUPR470101A0 (en) A molecular marker
HK1062022A1 (en) One-pack moisture curable epoxy resin composition.
AU1507201A (en) Marking device for pedestrian crossings
ES1043087Y (es) Distribuidor de tarjetas publicitarias mejorado.

Legal Events

Date Code Title Description
8363 Opposition against the patent