DE60128900D1 - Massenmarker - Google Patents
MassenmarkerInfo
- Publication number
- DE60128900D1 DE60128900D1 DE60128900T DE60128900T DE60128900D1 DE 60128900 D1 DE60128900 D1 DE 60128900D1 DE 60128900 T DE60128900 T DE 60128900T DE 60128900 T DE60128900 T DE 60128900T DE 60128900 D1 DE60128900 D1 DE 60128900D1
- Authority
- DE
- Germany
- Prior art keywords
- mass
- label
- labels
- group
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0006141 | 2000-03-14 | ||
GBGB0006141.6A GB0006141D0 (en) | 2000-03-14 | 2000-03-14 | Mass labels |
PCT/GB2001/001122 WO2001068664A2 (en) | 2000-03-14 | 2001-03-14 | Mass labels |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60128900D1 true DE60128900D1 (de) | 2007-07-26 |
DE60128900T2 DE60128900T2 (de) | 2008-02-07 |
Family
ID=9887608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60128900T Expired - Lifetime DE60128900T2 (de) | 2000-03-14 | 2001-03-14 | Massenmarker |
Country Status (15)
Country | Link |
---|---|
US (3) | US7294456B2 (de) |
EP (2) | EP1806586B1 (de) |
JP (1) | JP4608171B2 (de) |
CN (2) | CN102839213A (de) |
AT (1) | ATE364841T1 (de) |
AU (2) | AU2001240834B2 (de) |
CA (1) | CA2403114C (de) |
DE (1) | DE60128900T2 (de) |
DK (1) | DK1275004T3 (de) |
ES (2) | ES2389510T3 (de) |
GB (1) | GB0006141D0 (de) |
IL (2) | IL151732A0 (de) |
NO (1) | NO330733B1 (de) |
PT (1) | PT1275004E (de) |
WO (1) | WO2001068664A2 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999002728A1 (en) * | 1997-07-11 | 1999-01-21 | Brax Group Limited | Characterising nucleic acids |
AU8356201A (en) * | 2000-08-11 | 2002-02-25 | Agilix Corp | Ultra-sensitive detection systems |
ATE483161T1 (de) * | 2001-04-03 | 2010-10-15 | Thermo Finnigan Llc | Zur vereinfachung komplexer peptidgemische geeignete verfahren und kits |
DE60223696T2 (de) | 2001-09-14 | 2009-01-29 | Electrophoretics Ltd., Cobham | Massenmarker |
AU2002365271B2 (en) * | 2001-11-06 | 2008-12-11 | Agilix Corporation | Sensitive coded detection systems |
DE60231845D1 (de) * | 2001-12-11 | 2009-05-14 | Univ New Jersey Med | Diagnoseverfahren für proteinprofilierung |
AU2003224253A1 (en) | 2002-04-04 | 2003-10-27 | Electrophoretics Limited | Method for characterising analytes |
EP1588145B1 (de) | 2003-01-30 | 2011-07-06 | Life Technologies Corporation | Verfahren, mixturen, kits und zusammensetzungen bezüglich der analytbestimmung |
GB0306756D0 (en) * | 2003-03-24 | 2003-04-30 | Xzillion Gmbh & Co Kg | Mass labels |
US20060263886A1 (en) * | 2003-11-14 | 2006-11-23 | Eric Peters | Fluorous labeling for selective processing of biologically-derived samples |
US20050148087A1 (en) | 2004-01-05 | 2005-07-07 | Applera Corporation | Isobarically labeled analytes and fragment ions derived therefrom |
US20050148771A1 (en) | 2004-01-05 | 2005-07-07 | Applera Corporation. | Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof |
US7355045B2 (en) | 2004-01-05 | 2008-04-08 | Applera Corporation | Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof |
WO2005085869A2 (en) * | 2004-03-01 | 2005-09-15 | Applera Corporation | Determination of analyte characteristics based upon binding properties |
WO2005101017A1 (en) * | 2004-04-07 | 2005-10-27 | Genentech, Inc. | Mass spectrometry of antibody conjugates |
CA2567459A1 (en) * | 2004-05-19 | 2005-12-01 | Applera Corporation | Expression quantification using mass spectrometry |
US20070054345A1 (en) * | 2004-05-19 | 2007-03-08 | Hunter Christie L | Expression quantification using mass spectrometry |
US20080206737A1 (en) * | 2004-05-19 | 2008-08-28 | Hunter Christie L | Expression quantification using mass spectrometry |
EP1756307A1 (de) | 2004-05-20 | 2007-02-28 | Trillion Genomics Limited | Verwendung massenmarkierter sonden zum nachweis von zielnukleinsäuren mittels massenspektrometrie |
US20070048752A1 (en) * | 2004-07-12 | 2007-03-01 | Applera Corporation | Mass tags for quantitative analyses |
WO2006017208A1 (en) * | 2004-07-12 | 2006-02-16 | Applera Corporation | Mass tags for quantitative analyses |
CA2575675A1 (en) | 2004-07-30 | 2006-03-09 | Adeza Biomedical Corporation | Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin |
JP2008529035A (ja) * | 2005-02-03 | 2008-07-31 | パーキンエルマー エルエーエス,インク. | 多次元シグナルを用いる超高感度検出システム |
US20070037286A1 (en) * | 2005-02-09 | 2007-02-15 | Subhasish Purkayastha | Thyroxine-containing compound analysis methods |
US20060183238A1 (en) * | 2005-02-09 | 2006-08-17 | Applera Corporation | Amine-containing compound analysis methods |
GB0515323D0 (en) | 2005-07-26 | 2005-08-31 | Electrophoretics Ltd | Mass labels |
JP4651094B2 (ja) * | 2005-08-09 | 2011-03-16 | キヤノン株式会社 | 標識されたプローブ結合物体、その製造方法、及びその利用方法 |
GB0518585D0 (en) | 2005-09-12 | 2005-10-19 | Electrophoretics Ltd | Mass labels |
WO2007078229A1 (en) * | 2006-01-05 | 2007-07-12 | Ge Healthcare Bio-Sciences Ab | Kit and method for mass labelling |
US7902345B2 (en) * | 2006-12-05 | 2011-03-08 | Sequenom, Inc. | Detection and quantification of biomolecules using mass spectrometry |
US8133701B2 (en) * | 2006-12-05 | 2012-03-13 | Sequenom, Inc. | Detection and quantification of biomolecules using mass spectrometry |
US7728287B2 (en) * | 2007-03-01 | 2010-06-01 | Lawrence Livermore National Security, Llc | Imaging mass spectrometer with mass tags |
GB0704764D0 (en) | 2007-03-12 | 2007-04-18 | Electrophoretics Ltd | Isobarically labelled reagents and methods of their use |
WO2009032781A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for universal size-specific polymerase chain reaction |
GB0809488D0 (en) | 2008-05-23 | 2008-07-02 | Electrophoretics Ltd | Mass spectrometric analysis |
GB0811574D0 (en) * | 2008-06-24 | 2008-07-30 | Trillion Genomics Ltd | Characterising planar samples by mass spectrometry |
EP2356259A4 (de) * | 2008-10-30 | 2012-11-14 | Sequenom Inc | Produkte und verfahren zur multiplex-identifizierung von nukleinsäuren |
EP2406634A4 (de) | 2009-03-10 | 2013-06-19 | Univ Maryland | Isobare deuterium-markierungsreagenzien für quantitative analyse |
GB0916881D0 (en) * | 2009-09-25 | 2009-11-11 | Electrophoretics Ltd | Mass labels |
GB0921665D0 (en) | 2009-12-10 | 2010-01-27 | Trillion Genomics Ltd | Phobes |
US8309359B2 (en) | 2010-01-15 | 2012-11-13 | California Institute Of Technology | Isobaric tags for analyte detection and quantification |
US8372653B2 (en) * | 2010-01-22 | 2013-02-12 | Dh Technologies Development Pte. Ltd. | Mass tag reagents for simultaneous quantitation and identification of small molecules |
ES2676183T3 (es) | 2010-07-02 | 2018-07-17 | Ventana Medical Systems, Inc. | Detección de dianas usando marcas de masa y espectrometría de masas |
US8461987B2 (en) * | 2010-11-17 | 2013-06-11 | Theodosios Kountotsis | System and method for performing chemical analysis of fingerprints for providing at least one response |
WO2012159089A1 (en) * | 2011-05-19 | 2012-11-22 | Sequenom, Inc. | Products and processes for multiplex nucleic acid identification |
US9388132B2 (en) | 2011-09-15 | 2016-07-12 | Wisconsin Alumni Research Foundation | Isobaric tandem mass tags for quantitative proteomics and peptidomics |
WO2013170067A1 (en) | 2012-05-10 | 2013-11-14 | Thermo Finnigan Llc | Method for highly multiplexed quantitation of peptides by mass spectrometry and labeling reagent sets therefor |
US9366678B2 (en) | 2012-10-25 | 2016-06-14 | Wisconsin Alumni Research Foundation | Neutron encoded mass tags for analyte quantification |
CN105102977A (zh) * | 2012-12-26 | 2015-11-25 | 奎斯特诊断投资公司 | 通过质谱法的c肽检测 |
JP5569761B1 (ja) * | 2013-03-29 | 2014-08-13 | シャープ株式会社 | 分析方法 |
GB201308765D0 (en) * | 2013-05-15 | 2013-06-26 | Electrophoretics Ltd | Mass Tag Reagents |
GB201322567D0 (en) | 2013-12-19 | 2014-02-05 | Electrophoretics Ltd | Mass labels |
GB201410523D0 (en) | 2014-06-12 | 2014-07-30 | Electrophoretics Ltd | Mass labels |
AU2016250849A1 (en) | 2015-04-24 | 2017-11-02 | Agena Bioscience, Inc. | Multiplex methods for detection and quantification of minor variants |
US10233489B2 (en) | 2015-04-24 | 2019-03-19 | Agena Bioscience, Inc. | Multiplexed method for the identification and quantitation of minor alleles and polymorphisms |
GB201511508D0 (en) * | 2015-07-01 | 2015-08-12 | Ge Healthcare Bio Sciences Ab | Method for determining a size of biomolecules |
GB201521919D0 (en) | 2015-12-11 | 2016-01-27 | Electrophoretics Ltd | Isobaric mass labels |
GB201521903D0 (en) | 2015-12-11 | 2016-01-27 | Electrophoretics Ltd | Isorbaric mass labels |
CN108700551B (zh) * | 2016-02-22 | 2021-12-03 | 株式会社岛津制作所 | 唾液酸糖链解析方法 |
JP7051871B2 (ja) * | 2016-12-23 | 2022-04-11 | エフ.ホフマン-ラ ロシュ アーゲー | 分析系におけるプロセス中に試薬を同定するための方法 |
JP7046070B2 (ja) * | 2016-12-23 | 2022-04-01 | エフ.ホフマン-ラ ロシュ アーゲー | 分析系におけるプロセス中に試薬を同定するための方法 |
WO2018115243A1 (en) * | 2016-12-23 | 2018-06-28 | Roche Diagnostics Gmbh | Method for tracking a sample identity during a process in an analysis system |
JP2022526128A (ja) * | 2019-03-21 | 2022-05-23 | シー2センス, インコーポレイテッド | 揮発性イオンの検出のためのシステムおよび関連する方法 |
GB201907792D0 (en) | 2019-05-31 | 2019-07-17 | Thermo Fisher Scient Bremen Gmbh | Deconvolution of mass spectromerty data |
EP4047371A1 (de) | 2021-02-18 | 2022-08-24 | Thermo Fisher Scientific (Bremen) GmbH | Verfahren und vorrichtung zur analyse von proben von biomolekülen mittels massenspektrometrie mit datenunabhängiger erfassung |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5252296A (en) | 1990-05-15 | 1993-10-12 | Chiron Corporation | Method and apparatus for biopolymer synthesis |
GB9315847D0 (en) | 1993-07-30 | 1993-09-15 | Isis Innovation | Tag reagent and assay method |
JPH08145948A (ja) * | 1994-11-16 | 1996-06-07 | Sumitomo Chem Co Ltd | 還元性オリゴ糖の質量分析法 |
US6027890A (en) * | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
ES2144846T5 (es) | 1996-01-23 | 2006-07-16 | Qiagen Genomics, Inc. | Metodos y composiciones para determinar la secuencia de moleculas de acidos nucleicos. |
AU2217597A (en) * | 1996-03-18 | 1997-10-22 | Sequenom, Inc. | Dna sequencing by mass spectrometry |
EP0863858B1 (de) | 1996-04-08 | 2004-02-04 | Glaxo Group Limited | Auf masse basierte kodierung und qualitative analyse von kombinatorischen bibliotheken |
GB9620769D0 (en) | 1996-10-04 | 1996-11-20 | Brax Genomics Ltd | Nucleic acid sequencing |
JPH10123096A (ja) * | 1996-10-22 | 1998-05-15 | Sumitomo Chem Co Ltd | シアロオリゴ糖の質量分析法 |
DE69735445T2 (de) | 1996-12-10 | 2006-08-10 | Sequenom, Inc., San Diego | Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung |
DE69838519T2 (de) * | 1997-01-15 | 2008-07-03 | Xzillion Gmbh & Co. Kg | Massenmarkierte Hybridisierungssonden |
WO1999002728A1 (en) * | 1997-07-11 | 1999-01-21 | Brax Group Limited | Characterising nucleic acids |
GB9718921D0 (en) | 1997-09-05 | 1997-11-12 | Brax Genomics Ltd | Catalytically generated mass labels |
CA2303790A1 (en) | 1997-09-15 | 1999-03-25 | Brax Group Limited | Characterising nucleic acid by mass spectrometry |
FI106679B (fi) * | 1997-12-16 | 2001-03-15 | Nokia Networks Oy | Optinen vastaanotin |
GB9815163D0 (en) * | 1998-07-13 | 1998-09-09 | Brax Genomics Ltd | Compounds |
GB9823646D0 (en) * | 1997-12-19 | 1998-12-23 | Brax Genomics Ltd | Compounds for mass spectrometry |
AU8356201A (en) | 2000-08-11 | 2002-02-25 | Agilix Corp | Ultra-sensitive detection systems |
US9722639B2 (en) | 2013-05-01 | 2017-08-01 | Qorvo Us, Inc. | Carrier aggregation arrangements for mobile devices |
US9701046B2 (en) | 2013-06-21 | 2017-07-11 | Pavestone, LLC | Method and apparatus for dry cast facing concrete deposition |
US9187086B1 (en) | 2014-05-22 | 2015-11-17 | Ford Global Technologies, Llc | Clutch control to enter powersplit hybrid powertrain parallel mode |
US9701070B2 (en) | 2014-11-06 | 2017-07-11 | Lockheed Martin Corporation | Mandrel forming for discrete wing skin stiffeners |
-
2000
- 2000-03-14 GB GBGB0006141.6A patent/GB0006141D0/en not_active Ceased
-
2001
- 2001-03-14 ES ES07075074T patent/ES2389510T3/es not_active Expired - Lifetime
- 2001-03-14 JP JP2001567754A patent/JP4608171B2/ja not_active Expired - Lifetime
- 2001-03-14 ES ES01911912T patent/ES2287104T3/es not_active Expired - Lifetime
- 2001-03-14 EP EP07075074A patent/EP1806586B1/de not_active Expired - Lifetime
- 2001-03-14 US US10/221,666 patent/US7294456B2/en not_active Expired - Lifetime
- 2001-03-14 WO PCT/GB2001/001122 patent/WO2001068664A2/en active IP Right Grant
- 2001-03-14 AU AU2001240834A patent/AU2001240834B2/en not_active Expired
- 2001-03-14 CA CA002403114A patent/CA2403114C/en not_active Expired - Lifetime
- 2001-03-14 IL IL15173201A patent/IL151732A0/xx unknown
- 2001-03-14 DK DK01911912T patent/DK1275004T3/da active
- 2001-03-14 AT AT01911912T patent/ATE364841T1/de active
- 2001-03-14 PT PT01911912T patent/PT1275004E/pt unknown
- 2001-03-14 DE DE60128900T patent/DE60128900T2/de not_active Expired - Lifetime
- 2001-03-14 CN CN2012102853264A patent/CN102839213A/zh active Pending
- 2001-03-14 EP EP01911912A patent/EP1275004B1/de not_active Expired - Lifetime
- 2001-03-14 AU AU4083401A patent/AU4083401A/xx active Pending
- 2001-03-14 CN CN018090419A patent/CN1427953B/zh not_active Expired - Lifetime
-
2002
- 2002-09-12 NO NO20024344A patent/NO330733B1/no not_active IP Right Cessation
- 2002-09-12 IL IL151732A patent/IL151732A/en active IP Right Grant
-
2007
- 2007-08-20 US US11/841,707 patent/US7816304B2/en not_active Expired - Lifetime
- 2007-08-20 US US11/894,735 patent/US7825069B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7294456B2 (en) | 2007-11-13 |
CA2403114C (en) | 2007-07-31 |
CN1427953A (zh) | 2003-07-02 |
US20080167197A1 (en) | 2008-07-10 |
CA2403114A1 (en) | 2001-09-20 |
IL151732A0 (en) | 2003-04-10 |
PT1275004E (pt) | 2007-08-14 |
AU2001240834B2 (en) | 2005-11-17 |
IL151732A (en) | 2008-11-03 |
US20080145850A1 (en) | 2008-06-19 |
NO20024344D0 (no) | 2002-09-12 |
DE60128900T2 (de) | 2008-02-07 |
DK1275004T3 (da) | 2007-10-15 |
ES2287104T3 (es) | 2007-12-16 |
JP4608171B2 (ja) | 2011-01-05 |
NO330733B1 (no) | 2011-06-27 |
US20030194717A1 (en) | 2003-10-16 |
JP2003529059A (ja) | 2003-09-30 |
WO2001068664A2 (en) | 2001-09-20 |
AU4083401A (en) | 2001-09-24 |
US7816304B2 (en) | 2010-10-19 |
ES2389510T3 (es) | 2012-10-26 |
CN1427953B (zh) | 2012-08-29 |
ATE364841T1 (de) | 2007-07-15 |
US7825069B2 (en) | 2010-11-02 |
NO20024344L (no) | 2002-11-14 |
WO2001068664A3 (en) | 2002-03-21 |
EP1275004B1 (de) | 2007-06-13 |
EP1275004A2 (de) | 2003-01-15 |
EP1806586A1 (de) | 2007-07-11 |
CN102839213A (zh) | 2012-12-26 |
EP1806586B1 (de) | 2012-08-15 |
GB0006141D0 (en) | 2000-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |