DE60127134D1 - Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel - Google Patents

Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel

Info

Publication number
DE60127134D1
DE60127134D1 DE60127134T DE60127134T DE60127134D1 DE 60127134 D1 DE60127134 D1 DE 60127134D1 DE 60127134 T DE60127134 T DE 60127134T DE 60127134 T DE60127134 T DE 60127134T DE 60127134 D1 DE60127134 D1 DE 60127134D1
Authority
DE
Germany
Prior art keywords
transdermal
active ingredient
new composition
appropriate therapeutic
ingredient use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60127134T
Other languages
English (en)
Other versions
DE60127134T2 (de
Inventor
Dario Carrara
Gabriel Porto
Jorge Rodriguez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antares Pharma IPL AG
Original Assignee
Antares Pharma IPL AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antares Pharma IPL AG filed Critical Antares Pharma IPL AG
Application granted granted Critical
Publication of DE60127134D1 publication Critical patent/DE60127134D1/de
Publication of DE60127134T2 publication Critical patent/DE60127134T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
DE60127134T 2000-08-03 2001-08-03 Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel Expired - Lifetime DE60127134T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP0007533 2000-08-03
WOPCT/EP00/07533 2000-08-03
PCT/EP2001/009007 WO2002011768A1 (en) 2000-08-03 2001-08-03 Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels

Publications (2)

Publication Number Publication Date
DE60127134D1 true DE60127134D1 (de) 2007-04-19
DE60127134T2 DE60127134T2 (de) 2007-11-08

Family

ID=8164048

Family Applications (3)

Application Number Title Priority Date Filing Date
DE60127277T Expired - Lifetime DE60127277T2 (de) 2000-08-03 2001-08-03 Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert
DE60127134T Expired - Lifetime DE60127134T2 (de) 2000-08-03 2001-08-03 Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel
DE60143360T Expired - Lifetime DE60143360D1 (de) 2000-08-03 2001-08-03 Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60127277T Expired - Lifetime DE60127277T2 (de) 2000-08-03 2001-08-03 Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60143360T Expired - Lifetime DE60143360D1 (de) 2000-08-03 2001-08-03 Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert

Country Status (12)

Country Link
US (2) US7214381B2 (de)
EP (4) EP1307232B1 (de)
JP (1) JP2004505931A (de)
KR (1) KR100856523B1 (de)
AR (1) AR030312A1 (de)
AT (3) ATE485837T1 (de)
AU (2) AU8206401A (de)
CA (1) CA2418135C (de)
DE (3) DE60127277T2 (de)
ES (2) ES2283665T3 (de)
NZ (1) NZ524423A (de)
WO (1) WO2002011768A1 (de)

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ATE356636T1 (de) 2007-04-15
ATE355854T1 (de) 2007-03-15
DE60143360D1 (de) 2010-12-09
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US7404965B2 (en) 2008-07-29
KR100856523B1 (ko) 2008-09-04
ATE485837T1 (de) 2010-11-15
EP1325752A2 (de) 2003-07-09
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EP1307232A1 (de) 2003-05-07
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US20070098775A1 (en) 2007-05-03
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AU8206401A (en) 2002-02-18
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