DE60123833D1 - Entwurf und verwendung von verbesserten zink-chelatbildenden peptiden zur regulation von matrix-metalloproteinasen - Google Patents

Entwurf und verwendung von verbesserten zink-chelatbildenden peptiden zur regulation von matrix-metalloproteinasen

Info

Publication number
DE60123833D1
DE60123833D1 DE60123833T DE60123833T DE60123833D1 DE 60123833 D1 DE60123833 D1 DE 60123833D1 DE 60123833 T DE60123833 T DE 60123833T DE 60123833 T DE60123833 T DE 60123833T DE 60123833 D1 DE60123833 D1 DE 60123833D1
Authority
DE
Germany
Prior art keywords
chelat
design
matrix metal
improved zinc
mmp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60123833T
Other languages
English (en)
Other versions
DE60123833T2 (de
Inventor
Stephen Quirk
David John Tyrrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kimberly Clark Worldwide Inc
Kimberly Clark Corp
Original Assignee
Kimberly Clark Worldwide Inc
Kimberly Clark Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Worldwide Inc, Kimberly Clark Corp filed Critical Kimberly Clark Worldwide Inc
Application granted granted Critical
Publication of DE60123833D1 publication Critical patent/DE60123833D1/de
Publication of DE60123833T2 publication Critical patent/DE60123833T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
DE60123833T 2000-12-29 2001-12-21 Entwurf und verwendung von verbesserten zink-chelatbildenden peptiden zur regulation von matrix-metalloproteinasen Expired - Lifetime DE60123833T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US753139 2000-12-29
US09/753,139 US7041787B2 (en) 2000-12-29 2000-12-29 Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
PCT/US2001/049276 WO2002053173A2 (en) 2000-12-29 2001-12-21 Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases

Publications (2)

Publication Number Publication Date
DE60123833D1 true DE60123833D1 (de) 2006-11-23
DE60123833T2 DE60123833T2 (de) 2007-11-29

Family

ID=25029322

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60123833T Expired - Lifetime DE60123833T2 (de) 2000-12-29 2001-12-21 Entwurf und verwendung von verbesserten zink-chelatbildenden peptiden zur regulation von matrix-metalloproteinasen

Country Status (9)

Country Link
US (1) US7041787B2 (de)
EP (1) EP1348024B1 (de)
KR (1) KR100818874B1 (de)
AT (1) ATE342352T1 (de)
AU (1) AU2002231087A1 (de)
CA (1) CA2431853A1 (de)
DE (1) DE60123833T2 (de)
MX (1) MXPA03005903A (de)
WO (1) WO2002053173A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US6989139B2 (en) * 2000-02-15 2006-01-24 Bristol-Myers Squibb Pharma Company Matrix metalloproteinase inhibitors
WO2004007520A2 (en) * 2002-07-12 2004-01-22 Medarex, Inc. Methods and compositions for preventing oxidative degradation of proteins
US20100131051A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Systems and Methods for Treatment of Aneurysms Using Zinc Chelator(s)
US20100131001A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Targeted Drug Delivery for Aneurysm Treatment
WO2010070076A1 (en) 2008-12-19 2010-06-24 Crystax Pharmaceuticals, S.L. Alkanoic acid derivatives and their therapeutic use as hdac inhibitors
KR101363455B1 (ko) * 2011-09-09 2014-02-21 (주)케어젠 매트릭스 메탈로프로테아제 활성 억제 펩타이드 및 이의 용도
US9782457B2 (en) * 2011-10-07 2017-10-10 Tissue Repair Company Flowable formulations for tissue repair and regeneration
WO2015073538A2 (en) * 2013-11-12 2015-05-21 Echogen, Inc. Interaction with metalloenzymes
CN104710525B (zh) * 2015-03-18 2020-08-04 浙江海洋学院 一种金枪鱼鱼骨胶原蛋白源锌螯合胶原肽及其制备方法和用途

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Also Published As

Publication number Publication date
WO2002053173A2 (en) 2002-07-11
KR20030064885A (ko) 2003-08-02
WO2002053173A3 (en) 2003-04-10
MXPA03005903A (es) 2003-09-10
AU2002231087A1 (en) 2002-07-16
EP1348024A2 (de) 2003-10-01
CA2431853A1 (en) 2002-07-11
DE60123833T2 (de) 2007-11-29
US20030073808A1 (en) 2003-04-17
KR100818874B1 (ko) 2008-04-01
ATE342352T1 (de) 2006-11-15
US7041787B2 (en) 2006-05-09
EP1348024B1 (de) 2006-10-11

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