DE60118933D1 - Matrix zur aufnahme von arzneimitteln - Google Patents

Matrix zur aufnahme von arzneimitteln

Info

Publication number
DE60118933D1
DE60118933D1 DE60118933T DE60118933T DE60118933D1 DE 60118933 D1 DE60118933 D1 DE 60118933D1 DE 60118933 T DE60118933 T DE 60118933T DE 60118933 T DE60118933 T DE 60118933T DE 60118933 D1 DE60118933 D1 DE 60118933D1
Authority
DE
Germany
Prior art keywords
medicament
monomer
matrix
vivo
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118933T
Other languages
English (en)
Other versions
DE60118933T2 (de
Inventor
J Chudzik
P Everson
A Amos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Surmodics Inc
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc filed Critical Surmodics Inc
Application granted granted Critical
Publication of DE60118933D1 publication Critical patent/DE60118933D1/de
Publication of DE60118933T2 publication Critical patent/DE60118933T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22—Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
DE60118933T 2000-08-15 2001-07-09 Matrix zur aufnahme von arzneimitteln Expired - Lifetime DE60118933T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22546500P 2000-08-15 2000-08-15
US225465P 2000-08-15
PCT/US2001/041309 WO2002013871A2 (en) 2000-08-15 2001-07-09 Medicament incorporation matrix

Publications (2)

Publication Number Publication Date
DE60118933D1 true DE60118933D1 (de) 2006-05-24
DE60118933T2 DE60118933T2 (de) 2006-11-30

Family

ID=22844973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118933T Expired - Lifetime DE60118933T2 (de) 2000-08-15 2001-07-09 Matrix zur aufnahme von arzneimitteln

Country Status (9)

Country Link
US (2) US7056533B2 (de)
EP (1) EP1309360B1 (de)
JP (1) JP2004520088A (de)
AT (1) ATE323517T1 (de)
AU (2) AU2001281304B2 (de)
CA (1) CA2419379C (de)
DE (1) DE60118933T2 (de)
MX (1) MXPA03001406A (de)
WO (1) WO2002013871A2 (de)

Families Citing this family (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224539A1 (de) * 1999-10-14 2002-07-24 Advanced Micro Devices, Inc. Vorrichtung und verfahren zum zwischenspeichern von ausrichtungsinformation
US20050002986A1 (en) * 2000-05-12 2005-01-06 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
JP2004520088A (ja) 2000-08-15 2004-07-08 サーモディックス，インコーポレイティド 薬剤混和マトリックス
DE60124285T3 (de) 2000-09-29 2011-03-17 Cordis Corp., Miami Lakes Beschichtete medizinische geräte
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20060222756A1 (en) * 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US8182527B2 (en) * 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
MXPA04003162A (es) * 2001-10-05 2005-01-25 Surmodics Inc Recubrimientos de particulas inmovilizadas y usos de los mismos.
AU2002358421A1 (en) * 2001-11-23 2003-06-10 Feg Textiltechnik Forschungs- Und Entwicklungsgesellschaft Mbh Surface-modified textile product and a corresponding method for surface modification
US6706408B2 (en) 2002-05-16 2004-03-16 Surmodics, Inc. Silane coating composition
US7314484B2 (en) * 2002-07-02 2008-01-01 The Foundry, Inc. Methods and devices for treating aneurysms
US20040044404A1 (en) * 2002-08-30 2004-03-04 Stucke Sean M. Retention coatings for delivery systems
US20040116564A1 (en) 2002-11-27 2004-06-17 Devlin Brian Gerrard Stabilization of poly(oxyalkylene) containing polymeric materials
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758880B2 (en) 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
JP4903555B2 (ja) * 2003-02-20 2012-03-28 ウィルソン−クック・メディカル・インコーポレーテッド 粘着性のコーティングを備えた医療器具及びその製造方法
JP4857111B2 (ja) * 2003-05-15 2012-01-18 アーチ ユーケイ バイオサイドズ リミテッド 酸コポリマー及び抗微生物剤を含む組成物、並びにその使用
US8603453B2 (en) * 2003-05-20 2013-12-10 Arch Uk Biocides Limited Antimicrobial polymeric biguanide and acidic co-polymer composition and method of use
DE10332680A1 (de) * 2003-07-18 2005-02-17 Biomet Deutschland Gmbh Verwendung von antiseptischen Wirkstoffen in PMMA-Knochenzementen
US20050064011A1 (en) * 2003-08-11 2005-03-24 Young-Ho Song Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis
US7566502B1 (en) 2003-09-17 2009-07-28 Allegiance Corporation Surface modification of elastomeric articles
WO2005037338A1 (en) * 2003-10-14 2005-04-28 Cook Incorporated Hydrophilic coated medical device
JP2007521847A (ja) * 2003-10-15 2007-08-09 タイコ ヘルスケア グループ リミテッド パートナーシップ 材料を結合する方法
US20050186258A1 (en) * 2004-02-20 2005-08-25 Shiping Wang Antimicrobial medical gloves
US20050267556A1 (en) * 2004-05-28 2005-12-01 Allan Shuros Drug eluting implants to prevent cardiac apoptosis
WO2006002112A1 (en) * 2004-06-18 2006-01-05 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
US8535700B2 (en) 2004-10-28 2013-09-17 Surmodics, Inc. Pro-fibrotic coatings
MX2007010147A (es) * 2005-02-22 2007-10-15 Tim T Nguyen Composicion farmaceutica para el tratamiento de la onicomicosis.
CN101253259A (zh) * 2005-07-20 2008-08-27 苏尔莫迪克斯公司 聚合物涂覆的纳米原纤结构和用于细胞维持和分化的方法
US8663673B2 (en) 2005-07-29 2014-03-04 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility
JP4992070B2 (ja) * 2005-07-29 2012-08-08 国立大学法人 岡山大学 生理活性物質固定化チタン材及びその製造方法
US20070054127A1 (en) * 2005-08-26 2007-03-08 Hergenrother Robert W Silane coating compositions, coating systems, and methods
US9974887B2 (en) 2005-10-04 2018-05-22 Clph, Llc Catheters with lubricious linings and methods for making and using them
US7550053B2 (en) * 2006-01-26 2009-06-23 Ilh, Llc Catheters with lubricious linings and methods for making and using them
US8740864B2 (en) 2005-11-17 2014-06-03 Becton, Dickinson And Company Patient fluid line access valve antimicrobial cap/cleaner
WO2007067697A2 (en) * 2005-12-07 2007-06-14 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
WO2007095576A2 (en) * 2006-02-14 2007-08-23 Enturia, Inc. Liquid applicator and method for reducing the concentration of by-products from antiseptic
US7638344B2 (en) * 2006-06-28 2009-12-29 Surmodics, Inc. Active agent eluting matrices with particulates
DE102006033312A1 (de) * 2006-07-17 2008-01-31 Heraeus Kulzer Gmbh Dentales Implantatsystemteil mit einer Beschichtung
WO2008039749A2 (en) * 2006-09-25 2008-04-03 Surmodics, Inc. Multi-layered coatings and methods for controlling elution of active agents
CA2898230C (en) 2007-01-10 2018-04-24 Purdue Research Foundation Polypeptide inhibitors of hsp27 kinase and uses therefor
PL2269664T3 (pl) 2007-01-21 2013-03-29 Hemoteq Ag Wyrób medyczny do leczenia niedrożności układów ciała i do zapobiegania ponownej niedrożności
US20080188445A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
US20080188446A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
CA2631049A1 (en) * 2007-05-10 2008-11-10 Mcmaster University Photo-responsive delivery system
US7897195B2 (en) * 2007-06-15 2011-03-01 Abbott Cardiovascular Systems Inc. Devices for coating stents
US8003157B2 (en) 2007-06-15 2011-08-23 Abbott Cardiovascular Systems Inc. System and method for coating a stent
US8133553B2 (en) * 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
DK2185698T3 (en) 2007-08-07 2015-07-27 Purdue Research Foundation Kinase Inhibitors and Uses thereof
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US8608049B2 (en) * 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US20110230973A1 (en) * 2007-10-10 2011-09-22 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
US20090187256A1 (en) * 2008-01-21 2009-07-23 Zimmer, Inc. Method for forming an integral porous region in a cast implant
US20090198286A1 (en) * 2008-02-05 2009-08-06 Zimmer, Inc. Bone fracture fixation system
EP2271379B1 (de) * 2008-03-28 2015-11-25 SurModics, Inc. Einführbare medizinische vorrichtungen mit mikroteilchen-assoziierten elastischen substraten und verfahren zur arzneimittelabgabe
US20090269406A1 (en) * 2008-04-02 2009-10-29 Alyssa Panitch Therapeutic uses of biocompatible biogel compositions
WO2009126830A2 (en) * 2008-04-09 2009-10-15 Surmodics, Inc. Delivery of nucleic acid complexes from materials including negatively charged groups
DE102008040786A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Biokorrodierbares Implantat mit einer Beschichtung enthaltend eine wirkstofftragende Polymermatrix
DE102008040787A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Biokorrodierbares Implantat mit einer Beschichtung enthaltend ein Hydrogel
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US20100135949A1 (en) * 2008-12-01 2010-06-03 Becton, Dickinson And Company Antimicrobial compositions
WO2010068692A1 (en) * 2008-12-10 2010-06-17 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US7704935B1 (en) * 2009-01-06 2010-04-27 Becton, Dickinson And Company Chlorhexidine acetate antiseptic cleaning agent
DE102009011991A1 (de) * 2009-03-05 2010-09-09 Peter Hildebrandt Chirurgisches Implantat mit einem Träger in flächiger Form
US20100247600A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Therapeutic drug eluting implant cover and method of making the same
US9414864B2 (en) 2009-04-15 2016-08-16 Warsaw Orthopedic, Inc. Anterior spinal plate with preformed drug-eluting device affixed thereto
US9078712B2 (en) * 2009-04-15 2015-07-14 Warsaw Orthopedic, Inc. Preformed drug-eluting device to be affixed to an anterior spinal plate
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US8821455B2 (en) 2009-07-09 2014-09-02 Becton, Dickinson And Company Antimicrobial coating for dermally invasive devices
US10369256B2 (en) 2009-07-10 2019-08-06 Boston Scientific Scimed, Inc. Use of nanocrystals for drug delivery from a balloon
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 薬剤送達バルーンの製造方法
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
US8567340B2 (en) 2009-08-12 2013-10-29 Abbott Cardiovascular Systems Inc. System and method for coating a medical device
JP2011104346A (ja) * 2009-10-22 2011-06-02 Neocel:Kk 人工透析用具
ES2359321B1 (es) * 2009-11-10 2012-03-26 Consejo Superior De Investigaciones Cientificas (Csis) Pol�?meros hidrófilos como sistemas de liberación de compuestos bioactivos en mallas de aplicación quirúrgica.
US8343525B2 (en) * 2009-12-22 2013-01-01 Becton, Dickinson And Company Chlorhexidine acetate antiseptic cleaning agent
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US8785713B2 (en) 2010-04-13 2014-07-22 Kci Licensing, Inc. Compositions with reactive ingredients, and wound dressings, apparatuses, and methods
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9480833B2 (en) 2010-07-15 2016-11-01 Becton, Dickinson And Company Antimicrobial IV access cap
EP2611476B1 (de) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Beschichtungsverfahren für wirkstofffreisetzungsballons mit wärmeinduziertem rewrap-gedächtnis
DE102011075808B4 (de) * 2010-09-10 2017-06-29 Biolitec Ag Implantat zur Anwendung bei einer photo-dynamischen Behandlung sowie Verfahren zur Herstellung des Implantats
US8722076B2 (en) * 2010-09-30 2014-05-13 Surmodics, Inc. Photochrome- or near IR dye-coupled polymeric matrices for medical articles
US9114107B2 (en) 2010-10-05 2015-08-25 Drexel University Compositions for inhibiting virus entry and promoting virolysis, and methods thereof
WO2012075367A1 (en) * 2010-12-02 2012-06-07 Med-El Elektromedizinische Geraete Gmbh Surface coating for biomedical implants and electrodes
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
BR112014017675B1 (pt) 2012-01-18 2021-06-22 Surmodics, Inc Revestimento para um dispositivo médico lubrificante com teor baixo de particulados, dispositivo médico e método de produção do mesmo
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
WO2013151991A1 (en) 2012-04-02 2013-10-10 Surmodics, Inc. Hydrophilic polymeric coatings for medical articles with visualization moiety
US9352119B2 (en) 2012-05-15 2016-05-31 Becton, Dickinson And Company Blood control IV catheter with antimicrobial properties
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9579486B2 (en) 2012-08-22 2017-02-28 Becton, Dickinson And Company Blood control IV catheter with antimicrobial properties
CA2889981A1 (en) 2012-10-29 2014-05-08 Ariste Medical, Inc. Polymer coating compositions and coated products
US9629945B2 (en) 2012-12-12 2017-04-25 Surmodics, Inc. Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence
US9399125B2 (en) 2013-02-13 2016-07-26 Becton, Dickinson And Company Needleless connector and access port disinfection cleaner and antimicrobial protection cap
US9695323B2 (en) 2013-02-13 2017-07-04 Becton, Dickinson And Company UV curable solventless antimicrobial compositions
US9750928B2 (en) 2013-02-13 2017-09-05 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator
US9039989B2 (en) 2013-02-13 2015-05-26 Becton, Dickinson And Company Disinfection cap for disinfecting a male luer end of an infusion therapy device
US9750927B2 (en) 2013-03-11 2017-09-05 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US9327095B2 (en) 2013-03-11 2016-05-03 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
CN111632578A (zh) 2013-04-01 2020-09-08 西托索尔本茨公司 交联聚合物材料的血液相容性修饰剂
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US9629978B2 (en) 2013-05-20 2017-04-25 Clph, Llc Catheters with intermediate layers and methods for making them
US9233138B2 (en) 2013-10-22 2016-01-12 Drexel University Compositions for promoting HIV-1 virolysis and methods using same
DE102013112048A1 (de) * 2013-10-31 2015-04-30 Technische Universität Darmstadt Photoreaktive Polymere, Verfahren zur Herstellung von nassfesten Papierprodukten und nassfestes Papierprodukt
US9283369B2 (en) 2014-02-20 2016-03-15 Becton, Dickinson And Company IV access port cap for providing antimicrobial protection
WO2015164524A1 (en) * 2014-04-22 2015-10-29 Ariste Medical, Inc. Methods and processes for application of drug delivery polymeric coatings
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US9675793B2 (en) 2014-04-23 2017-06-13 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
US10124088B2 (en) 2014-09-29 2018-11-13 Surmodics, Inc. Lubricious medical device elements
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
KR102496897B1 (ko) * 2015-03-31 2023-02-07 도레이 카부시키가이샤 공중합체 및 그것을 사용한 의료 디바이스, 의료용 분리막 모듈, 및 혈액 정화기
US20180221546A1 (en) * 2015-07-24 2018-08-09 Teleflex Medical Incorporated Implantable orthopedic devices having antimicrobial coatings
US11925578B2 (en) 2015-09-02 2024-03-12 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
US11174447B2 (en) 2015-12-29 2021-11-16 Surmodics, Inc. Lubricious coatings with surface salt groups
US10342898B2 (en) 2015-12-29 2019-07-09 Surmodics, Inc. Lubricious coatings with surface salt groups
CA3007670A1 (en) 2016-01-29 2017-08-03 Neovasc Tiara Inc. Prosthetic valve for avoiding obstruction of outflow
EP3442479A1 (de) 2016-04-20 2019-02-20 Harold Alexander Heitzmann Vorrichtung zur verabreichung eines bioresorbierbaren okularen medikaments
CN113893064A (zh) 2016-11-21 2022-01-07 内奥瓦斯克迪亚拉公司 用于快速收回经导管心脏瓣膜递送系统的方法和系统
US10576250B2 (en) 2016-12-13 2020-03-03 Becton, Dickinson And Company Securement dressing for vascular access device with skin adhesive application window
US10987486B2 (en) 2017-04-07 2021-04-27 Becton, Dickinson And Company Catheter securement device with window
WO2019036810A1 (en) 2017-08-25 2019-02-28 Neovasc Tiara Inc. TRANSCATHETER MITRAL VALVULE PROSTHESIS WITH SEQUENTIAL DEPLOYMENT
JP7167336B2 (ja) * 2018-11-02 2022-11-08 バイオナット ラブス リミテッド 小型化されたデバイスからのペイロード放出の磁気機械的トリガー
AU2019374743B2 (en) 2018-11-08 2022-03-03 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
CN111514379B (zh) * 2019-02-02 2022-03-15 江苏百赛飞生物科技有限公司 经外周静脉置入中心静脉导管及其制备方法
CN111569159B (zh) * 2019-02-15 2022-03-11 江苏百赛飞生物科技有限公司 一种输尿管导管及其制备方法
EP3946163A4 (de) 2019-04-01 2022-12-21 Neovasc Tiara Inc. Steuerbar einsetzbare klappenprothese
EP3952792A4 (de) 2019-04-10 2023-01-04 Neovasc Tiara Inc. Herzklappenprothese mit natürlichem blutfluss
CA3140925A1 (en) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Introducer with hemostasis mechanism
AU2020295566B2 (en) 2019-06-20 2023-07-20 Neovasc Tiara Inc. Low profile prosthetic mitral valve
US20210115350A1 (en) * 2019-10-21 2021-04-22 Biocoat, Inc. UV Cure Topcoatings For Medical Devices

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1720393A1 (de) 1967-06-03 1971-06-16 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung ungesaettigter Ester von Polymerisaten
US3767398A (en) 1971-10-26 1973-10-23 C Morgan Solid photoresist comprising a polyene and a polythiol
GB1390711A (en) 1973-04-19 1975-04-16 Grace W R & Co Image-forming process employing a polyene/polythiol composition
CS179567B1 (en) 1974-11-25 1977-11-30 Vladimir Stoy Ionogennic hydrophilic in water insoluble gels based on partial saponificated polymers or copolymers acrylonitrile and method of preparing them
US4304591A (en) 1978-01-25 1981-12-08 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
US4260538A (en) 1979-09-27 1981-04-07 The Budd Company Matured moldable thermosetting dual polyester resin system
US4401793A (en) 1981-09-04 1983-08-30 National Starch And Chemical Corporation Polymeric adducts with pendant polymerizable double bonds, their preparation and use as reactive thickeners in improved anaerobic compositions
US4442133A (en) 1982-02-22 1984-04-10 Greco Ralph S Antibiotic bonding of vascular prostheses and other implants
SE445884B (sv) 1982-04-30 1986-07-28 Medinvent Sa Anordning for implantation av en rorformig protes
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
JPS59135272A (ja) 1983-01-21 1984-08-03 Kuraray Co Ltd 接着剤
DE3323913C2 (de) 1983-07-02 1986-01-02 Th. Goldschmidt Ag, 4300 Essen Polyisobutylenbernsteinsäurehalbester, ihre Herstellung und ihre Verwendung zur Herstellung eines Klebemittels
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4778786A (en) 1985-04-03 1988-10-18 Minnetonka, Inc. Composition for transdermal drug delivery
DE3536077A1 (de) 1985-10-09 1987-04-09 Muehlbauer Ernst Kg Polymerisierbare saeure und saeurederivate enthaltende verbindungen, dieselben enthaltende mischungen und ihre verwendung
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4917686A (en) 1985-12-16 1990-04-17 Colorado Biomedical, Inc. Antimicrobial device and method
IE63321B1 (en) 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
JPS62223112A (ja) 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
SE453258B (sv) 1986-04-21 1988-01-25 Medinvent Sa Elastisk, sjelvexpanderande protes samt forfarande for dess framstellning
US4895566A (en) 1986-07-25 1990-01-23 C. R. Bard, Inc. Coating medical devices with cationic antibiotics
US5015479A (en) 1987-02-02 1991-05-14 Seamus Mulligan Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US5114719A (en) 1987-04-29 1992-05-19 Sabel Bernhard A Extended drug delivery of small, water-soluble molecules
US4846844A (en) 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
IT1215726B (it) 1988-01-18 1990-02-22 Alfa Wassermann Spa Formulazioni galeniche a cessione programmata.
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5169642A (en) 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5268182A (en) 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5013306A (en) 1989-01-18 1991-05-07 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5165952A (en) 1989-01-18 1992-11-24 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5602197A (en) 1989-05-30 1997-02-11 Corning Incorporated Reversible polymer gel binders for powder forming
JPH0366384A (ja) 1989-08-04 1991-03-22 Senjiyu Seiyaku Kk 生理活性物質放出制御システム
US5525348A (en) 1989-11-02 1996-06-11 Sts Biopolymers, Inc. Coating compositions comprising pharmaceutical agents
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5270358A (en) 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
BR9106379A (pt) 1990-04-26 1993-04-27 Wacker Chimie Gmbh Organo(polil)siloxanos com unidades de siloxano em posicao terminal que apresentam grupo orgamiloxi e hidrogenio
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
JP3286315B2 (ja) 1990-06-20 2002-05-27 アドバンスト ポリマー システムズ，インコーポレイティド 可溶性活性物質の調節された放出のための組成物及び方法
JP2559528B2 (ja) 1990-08-29 1996-12-04 株式会社日立製作所 光露光装置
WO1992015286A1 (en) 1991-02-27 1992-09-17 Nova Pharmaceutical Corporation Anti-infective and anti-inflammatory releasing systems for medical devices
WO1993000873A1 (en) 1991-07-03 1993-01-21 Sano Corporation Composition and method for transdermal delivery of diclofenac
FR2699406B1 (fr) * 1992-12-21 1995-03-10 Commissariat Energie Atomique Films à base de copolymères, leurs applications dans des systèmes transdermiques et leurs procédés de préparation.
KR0147482B1 (ko) 1993-01-19 1998-08-01 알렌 제이. 스피겔 피복 복합 스텐트
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US5769796A (en) 1993-05-11 1998-06-23 Target Therapeutics, Inc. Super-elastic composite guidewire
US5749837A (en) 1993-05-11 1998-05-12 Target Therapeutics, Inc. Enhanced lubricity guidewire
US5443455A (en) 1993-07-27 1995-08-22 Target Therapeutics, Inc. Guidewire and method of pretreating metal surfaces for subsequent polymer coating
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5689641A (en) 1993-10-01 1997-11-18 Vicor, Inc. Multimedia collaboration system arrangement for routing compressed AV signal through a participant site without decompressing the AV signal
US5554147A (en) 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US5965505A (en) 1994-04-13 1999-10-12 The Procter & Gamble Company Detergents containing a heavy metal sequestrant and a delayed release peroxyacid bleach system
US5603955A (en) 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
WO1996017592A2 (en) 1994-12-06 1996-06-13 The Procter & Gamble Company Shelf stable skin cleansing liquid with gel forming polymer, lipid and crystalline ethylene glycol fatty acid ester
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5702717A (en) 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
US5739210A (en) 1995-11-03 1998-04-14 Michigan State University Polymers comprising reversible hydrophobic functionalities
US5756145A (en) 1995-11-08 1998-05-26 Baylor College Of Medicine Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor
US5939090A (en) 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
US5997517A (en) 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US6004573A (en) 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6465525B1 (en) 1998-03-18 2002-10-15 Surmodics, Inc. Latent reactive blood compatible agents
US6007833A (en) * 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
ATE270590T1 (de) 1999-09-22 2004-07-15 Surmodics Inc Initiationsgruppentragendes wasserlösliches beschichtungsmittel und beschichtungsverfahren
JP2004520088A (ja) 2000-08-15 2004-07-08 サーモディックス，インコーポレイティド 薬剤混和マトリックス

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