DE60118933D1 - Matrix zur aufnahme von arzneimitteln - Google Patents

Matrix zur aufnahme von arzneimitteln

Info

Publication number
DE60118933D1
DE60118933D1 DE60118933T DE60118933T DE60118933D1 DE 60118933 D1 DE60118933 D1 DE 60118933D1 DE 60118933 T DE60118933 T DE 60118933T DE 60118933 T DE60118933 T DE 60118933T DE 60118933 D1 DE60118933 D1 DE 60118933D1
Authority
DE
Germany
Prior art keywords
medicament
monomer
matrix
vivo
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118933T
Other languages
English (en)
Other versions
DE60118933T2 (de
Inventor
J Chudzik
P Everson
A Amos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Surmodics Inc
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc filed Critical Surmodics Inc
Application granted granted Critical
Publication of DE60118933D1 publication Critical patent/DE60118933D1/de
Publication of DE60118933T2 publication Critical patent/DE60118933T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/145Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/22Lipids, fatty acids, e.g. prostaglandins, oils, fats, waxes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
DE60118933T 2000-08-15 2001-07-09 Matrix zur aufnahme von arzneimitteln Expired - Lifetime DE60118933T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22546500P 2000-08-15 2000-08-15
US225465P 2000-08-15
PCT/US2001/041309 WO2002013871A2 (en) 2000-08-15 2001-07-09 Medicament incorporation matrix

Publications (2)

Publication Number Publication Date
DE60118933D1 true DE60118933D1 (de) 2006-05-24
DE60118933T2 DE60118933T2 (de) 2006-11-30

Family

ID=22844973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118933T Expired - Lifetime DE60118933T2 (de) 2000-08-15 2001-07-09 Matrix zur aufnahme von arzneimitteln

Country Status (9)

Country Link
US (2) US7056533B2 (de)
EP (1) EP1309360B1 (de)
JP (1) JP2004520088A (de)
AT (1) ATE323517T1 (de)
AU (2) AU8130401A (de)
CA (1) CA2419379C (de)
DE (1) DE60118933T2 (de)
MX (1) MXPA03001406A (de)
WO (1) WO2002013871A2 (de)

Families Citing this family (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224539A1 (de) * 1999-10-14 2002-07-24 Advanced Micro Devices, Inc. Vorrichtung und verfahren zum zwischenspeichern von ausrichtungsinformation
US20050002986A1 (en) * 2000-05-12 2005-01-06 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
EP1309360B1 (de) 2000-08-15 2006-04-19 SurModics, Inc. Matrix zur aufnahme von arzneimitteln
US20060222756A1 (en) * 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
EP1322235B2 (de) 2000-09-29 2010-08-11 Cordis Corporation Beschichtete medizinische geräte
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US8182527B2 (en) * 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
MXPA04003162A (es) * 2001-10-05 2005-01-25 Surmodics Inc Recubrimientos de particulas inmovilizadas y usos de los mismos.
WO2003045461A1 (de) * 2001-11-23 2003-06-05 Feg Textiltechnik Forschungs- Und Entwicklungsgesellschaft Mbh Textiles erzeugnis mit oberflächenmodifikation und entsprechendes verfahren zur oberflächenmodifikation
US6706408B2 (en) * 2002-05-16 2004-03-16 Surmodics, Inc. Silane coating composition
US7314484B2 (en) 2002-07-02 2008-01-01 The Foundry, Inc. Methods and devices for treating aneurysms
US20040044404A1 (en) * 2002-08-30 2004-03-04 Stucke Sean M. Retention coatings for delivery systems
US20040116564A1 (en) * 2002-11-27 2004-06-17 Devlin Brian Gerrard Stabilization of poly(oxyalkylene) containing polymeric materials
US7776926B1 (en) 2002-12-11 2010-08-17 Advanced Cardiovascular Systems, Inc. Biocompatible coating for implantable medical devices
US7758880B2 (en) * 2002-12-11 2010-07-20 Advanced Cardiovascular Systems, Inc. Biocompatible polyacrylate compositions for medical applications
JP4903555B2 (ja) * 2003-02-20 2012-03-28 ウィルソン−クック・メディカル・インコーポレーテッド 粘着性のコーティングを備えた医療器具及びその製造方法
WO2004100664A1 (en) * 2003-05-15 2004-11-25 Arch Uk Biocides Limited Composition comprising an acidic copolymer and an antimicrobial agent and use thereof
US8603453B2 (en) * 2003-05-20 2013-12-10 Arch Uk Biocides Limited Antimicrobial polymeric biguanide and acidic co-polymer composition and method of use
DE10332680A1 (de) * 2003-07-18 2005-02-17 Biomet Deutschland Gmbh Verwendung von antiseptischen Wirkstoffen in PMMA-Knochenzementen
US20050064011A1 (en) * 2003-08-11 2005-03-24 Young-Ho Song Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis
US7566502B1 (en) 2003-09-17 2009-07-28 Allegiance Corporation Surface modification of elastomeric articles
WO2005037338A1 (en) * 2003-10-14 2005-04-28 Cook Incorporated Hydrophilic coated medical device
JP2007521847A (ja) * 2003-10-15 2007-08-09 タイコ ヘルスケア グループ リミテッド パートナーシップ 材料を結合する方法
US20050186258A1 (en) * 2004-02-20 2005-08-25 Shiping Wang Antimicrobial medical gloves
US20050267556A1 (en) * 2004-05-28 2005-12-01 Allan Shuros Drug eluting implants to prevent cardiac apoptosis
WO2006002112A1 (en) * 2004-06-18 2006-01-05 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release
US9011831B2 (en) 2004-09-30 2015-04-21 Advanced Cardiovascular Systems, Inc. Methacrylate copolymers for medical devices
WO2006050110A2 (en) * 2004-10-28 2006-05-11 Surmodics, Inc. Pro-fibrotic coatings comprising collagen for medical implants
CA2598445A1 (en) * 2005-02-22 2006-08-31 Tim T. Nguyen Method for treatment of onychomycosis
EP1904118B1 (de) * 2005-07-20 2018-01-17 Surmodics, Inc. Polymerbeschichtungen und verfahren zur zellanhaftung
US8663673B2 (en) 2005-07-29 2014-03-04 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release or hemocompatibility
JP4992070B2 (ja) * 2005-07-29 2012-08-08 国立大学法人 岡山大学 生理活性物質固定化チタン材及びその製造方法
US20070054127A1 (en) * 2005-08-26 2007-03-08 Hergenrother Robert W Silane coating compositions, coating systems, and methods
US7550053B2 (en) * 2006-01-26 2009-06-23 Ilh, Llc Catheters with lubricious linings and methods for making and using them
US9974887B2 (en) 2005-10-04 2018-05-22 Clph, Llc Catheters with lubricious linings and methods for making and using them
US8740864B2 (en) 2005-11-17 2014-06-03 Becton, Dickinson And Company Patient fluid line access valve antimicrobial cap/cleaner
US8262730B2 (en) 2005-12-07 2012-09-11 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
ES2877071T3 (es) * 2006-02-14 2021-11-16 Allegiance Corp Aplicador de líquido y procedimiento para reducir la concentración de subproductos de antiséptico
JP2009542671A (ja) * 2006-06-28 2009-12-03 サーモディクス,インコーポレイティド 微粒子を含む活性剤溶出マトリックス
DE102006033312A1 (de) * 2006-07-17 2008-01-31 Heraeus Kulzer Gmbh Dentales Implantatsystemteil mit einer Beschichtung
WO2008039749A2 (en) * 2006-09-25 2008-04-03 Surmodics, Inc. Multi-layered coatings and methods for controlling elution of active agents
AU2007342674B2 (en) * 2007-01-10 2013-09-19 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and uses therefor
EP2136853B1 (de) 2007-01-21 2013-04-10 Hemoteq AG Medizinprodukt zur behandlung von verschlüssen von körperdurchgängen und zur prävention drohender wiederverschlüsse
US20080188445A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
WO2008097851A1 (en) * 2007-02-02 2008-08-14 Warner Chilcott Company, Inc. Tetracycline compositions for topical administration
CA2631049A1 (en) * 2007-05-10 2008-11-10 Mcmaster University Photo-responsive delivery system
US8003157B2 (en) 2007-06-15 2011-08-23 Abbott Cardiovascular Systems Inc. System and method for coating a stent
US7897195B2 (en) 2007-06-15 2011-03-01 Abbott Cardiovascular Systems Inc. Devices for coating stents
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US8309521B2 (en) 2007-06-19 2012-11-13 Zimmer, Inc. Spacer with a coating thereon for use with an implant device
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
JP5703466B2 (ja) * 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation キナーゼ阻害薬およびその使用
GB0715514D0 (en) * 2007-08-10 2007-09-19 Tissuemed Ltd Coated medical devices
US8608049B2 (en) * 2007-10-10 2013-12-17 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US20110230973A1 (en) * 2007-10-10 2011-09-22 Zimmer, Inc. Method for bonding a tantalum structure to a cobalt-alloy substrate
US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
US20090187256A1 (en) * 2008-01-21 2009-07-23 Zimmer, Inc. Method for forming an integral porous region in a cast implant
US20090198286A1 (en) * 2008-02-05 2009-08-06 Zimmer, Inc. Bone fracture fixation system
EP2689789B1 (de) * 2008-03-28 2019-03-13 SurModics, Inc. Einführbare medizinische Vorrichtungen mit elastischen mikropartikelassoziierten Substraten und Verfahren zur Wirkstofffreisetzung
WO2009123759A2 (en) * 2008-04-02 2009-10-08 Moerae Matrix, Inc. Therapeutic uses of biocompatible biogel compositions
US20090263449A1 (en) * 2008-04-09 2009-10-22 Surmodics, Inc. Delivery of nucleic acid complexes from materials including negatively charged groups
DE102008040786A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Biokorrodierbares Implantat mit einer Beschichtung enthaltend eine wirkstofftragende Polymermatrix
DE102008040787A1 (de) * 2008-07-28 2010-02-04 Biotronik Vi Patent Ag Biokorrodierbares Implantat mit einer Beschichtung enthaltend ein Hydrogel
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US20100135949A1 (en) 2008-12-01 2010-06-03 Becton, Dickinson And Company Antimicrobial compositions
US9327008B2 (en) * 2008-12-10 2016-05-03 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US7704935B1 (en) * 2009-01-06 2010-04-27 Becton, Dickinson And Company Chlorhexidine acetate antiseptic cleaning agent
DE102009011991A1 (de) * 2009-03-05 2010-09-09 Peter Hildebrandt Chirurgisches Implantat mit einem Träger in flächiger Form
US20100247600A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Therapeutic drug eluting implant cover and method of making the same
US9414864B2 (en) 2009-04-15 2016-08-16 Warsaw Orthopedic, Inc. Anterior spinal plate with preformed drug-eluting device affixed thereto
US9078712B2 (en) * 2009-04-15 2015-07-14 Warsaw Orthopedic, Inc. Preformed drug-eluting device to be affixed to an anterior spinal plate
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US8821455B2 (en) 2009-07-09 2014-09-02 Becton, Dickinson And Company Antimicrobial coating for dermally invasive devices
EP3064230B1 (de) 2009-07-10 2019-04-10 Boston Scientific Scimed, Inc. Verwendung von nanokristallen für einen wirkstofffreisetzungsballon
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 薬剤送達バルーンの製造方法
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
US8567340B2 (en) 2009-08-12 2013-10-29 Abbott Cardiovascular Systems Inc. System and method for coating a medical device
JP2011104346A (ja) * 2009-10-22 2011-06-02 Neocel:Kk 人工透析用具
ES2359321B1 (es) * 2009-11-10 2012-03-26 Consejo Superior De Investigaciones Cientificas (Csis) Pol�?meros hidrófilos como sistemas de liberación de compuestos bioactivos en mallas de aplicación quirúrgica.
US8343525B2 (en) * 2009-12-22 2013-01-01 Becton, Dickinson And Company Chlorhexidine acetate antiseptic cleaning agent
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
WO2011130246A2 (en) * 2010-04-13 2011-10-20 Kci Licensing, Inc. Compositions with reactive ingredients, and wound dressings, apparatuses, and methods
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US9480833B2 (en) 2010-07-15 2016-11-01 Becton, Dickinson And Company Antimicrobial IV access cap
US8889211B2 (en) 2010-09-02 2014-11-18 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
DE102011075808B4 (de) * 2010-09-10 2017-06-29 Biolitec Ag Implantat zur Anwendung bei einer photo-dynamischen Behandlung sowie Verfahren zur Herstellung des Implantats
US8722076B2 (en) * 2010-09-30 2014-05-13 Surmodics, Inc. Photochrome- or near IR dye-coupled polymeric matrices for medical articles
WO2012048033A2 (en) * 2010-10-05 2012-04-12 Drexel University Novel compositions for inhibiting virus entry and promoting virolyisis, and methods thereof
AU2011336473A1 (en) * 2010-12-02 2013-06-06 Hemoteq Ag Surface coating for biomedical implants and electrodes
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
WO2013028208A1 (en) 2011-08-25 2013-02-28 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
WO2013109930A1 (en) 2012-01-18 2013-07-25 Surmodics, Inc. Lubricious medical device coating with low particulates
US9452218B2 (en) 2012-03-09 2016-09-27 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
WO2013151991A1 (en) 2012-04-02 2013-10-10 Surmodics, Inc. Hydrophilic polymeric coatings for medical articles with visualization moiety
US9352119B2 (en) 2012-05-15 2016-05-31 Becton, Dickinson And Company Blood control IV catheter with antimicrobial properties
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9579486B2 (en) 2012-08-22 2017-02-28 Becton, Dickinson And Company Blood control IV catheter with antimicrobial properties
EP2912121B1 (de) 2012-10-29 2019-09-25 Ariste Medical, LLC Polymerbeschichtungszusammensetzungen und beschichtete gegenstände
US9629945B2 (en) 2012-12-12 2017-04-25 Surmodics, Inc. Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence
US9399125B2 (en) 2013-02-13 2016-07-26 Becton, Dickinson And Company Needleless connector and access port disinfection cleaner and antimicrobial protection cap
US9695323B2 (en) 2013-02-13 2017-07-04 Becton, Dickinson And Company UV curable solventless antimicrobial compositions
US9750928B2 (en) 2013-02-13 2017-09-05 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator
US9039989B2 (en) 2013-02-13 2015-05-26 Becton, Dickinson And Company Disinfection cap for disinfecting a male luer end of an infusion therapy device
US9327095B2 (en) 2013-03-11 2016-05-03 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US9750927B2 (en) 2013-03-11 2017-09-05 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
JP2016514568A (ja) 2013-04-01 2016-05-23 サイトソーベンツ・コーポレーション 架橋ポリマー材料のための血液適合性改質剤
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US9629978B2 (en) 2013-05-20 2017-04-25 Clph, Llc Catheters with intermediate layers and methods for making them
US9233138B2 (en) 2013-10-22 2016-01-12 Drexel University Compositions for promoting HIV-1 virolysis and methods using same
DE102013112048A1 (de) * 2013-10-31 2015-04-30 Technische Universität Darmstadt Photoreaktive Polymere, Verfahren zur Herstellung von nassfesten Papierprodukten und nassfestes Papierprodukt
US9283369B2 (en) 2014-02-20 2016-03-15 Becton, Dickinson And Company IV access port cap for providing antimicrobial protection
AU2015249769A1 (en) * 2014-04-22 2016-11-10 Ariste Medical, Llc. Methods and processes for application of drug delivery polymeric coatings
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US9675793B2 (en) 2014-04-23 2017-06-13 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
CA2950187A1 (en) 2014-05-29 2015-12-03 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
US10124088B2 (en) 2014-09-29 2018-11-13 Surmodics, Inc. Lubricious medical device elements
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US10308745B2 (en) * 2015-03-31 2019-06-04 Toray Industries, Inc. Copolymer and medical device, separation membrane module for medical use, and blood purifier including the same
WO2017019494A1 (en) * 2015-07-24 2017-02-02 Teleflex Medical Incorporated Implantable orthopedic devices having antimicrobial coatings
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
US11174447B2 (en) 2015-12-29 2021-11-16 Surmodics, Inc. Lubricious coatings with surface salt groups
US10342898B2 (en) 2015-12-29 2019-07-09 Surmodics, Inc. Lubricious coatings with surface salt groups
US10433952B2 (en) 2016-01-29 2019-10-08 Neovasc Tiara Inc. Prosthetic valve for avoiding obstruction of outflow
CA3022830A1 (en) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
CN113893064A (zh) 2016-11-21 2022-01-07 内奥瓦斯克迪亚拉公司 用于快速收回经导管心脏瓣膜递送系统的方法和系统
US10576250B2 (en) 2016-12-13 2020-03-03 Becton, Dickinson And Company Securement dressing for vascular access device with skin adhesive application window
US10987486B2 (en) 2017-04-07 2021-04-27 Becton, Dickinson And Company Catheter securement device with window
EP3672530A4 (de) 2017-08-25 2021-04-14 Neovasc Tiara Inc. Sequentiell eingesetzte transkatheter-mitralklappenprothese
EP3873435A4 (de) * 2018-11-02 2022-11-09 Bionaut Labs Ltd. Magnetomechanische auslösung einer nutzlastfreigabe aus miniaturisierten vorrichtungen
WO2020093172A1 (en) 2018-11-08 2020-05-14 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
CN111514379B (zh) * 2019-02-02 2022-03-15 江苏百赛飞生物科技有限公司 经外周静脉置入中心静脉导管及其制备方法
CN111569159B (zh) * 2019-02-15 2022-03-11 江苏百赛飞生物科技有限公司 一种输尿管导管及其制备方法
WO2020206012A1 (en) 2019-04-01 2020-10-08 Neovasc Tiara Inc. Controllably deployable prosthetic valve
CN113924065A (zh) 2019-04-10 2022-01-11 内奥瓦斯克迪亚拉公司 具有自然血流的假体瓣膜
CN114025813A (zh) 2019-05-20 2022-02-08 内奥瓦斯克迪亚拉公司 具有止血机构的引入器
AU2020295566B2 (en) 2019-06-20 2023-07-20 Neovasc Tiara Inc. Low profile prosthetic mitral valve
US20210115350A1 (en) * 2019-10-21 2021-04-22 Biocoat, Inc. UV Cure Topcoatings For Medical Devices

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1720393A1 (de) 1967-06-03 1971-06-16 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung ungesaettigter Ester von Polymerisaten
US3767398A (en) 1971-10-26 1973-10-23 C Morgan Solid photoresist comprising a polyene and a polythiol
GB1390711A (en) 1973-04-19 1975-04-16 Grace W R & Co Image-forming process employing a polyene/polythiol composition
CS179567B1 (en) 1974-11-25 1977-11-30 Vladimir Stoy Ionogennic hydrophilic in water insoluble gels based on partial saponificated polymers or copolymers acrylonitrile and method of preparing them
US4304591A (en) 1978-01-25 1981-12-08 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers used as carriers for medicaments and pesticides
US4260538A (en) 1979-09-27 1981-04-07 The Budd Company Matured moldable thermosetting dual polyester resin system
US4401793A (en) 1981-09-04 1983-08-30 National Starch And Chemical Corporation Polymeric adducts with pendant polymerizable double bonds, their preparation and use as reactive thickeners in improved anaerobic compositions
US4442133A (en) 1982-02-22 1984-04-10 Greco Ralph S Antibiotic bonding of vascular prostheses and other implants
SE445884B (sv) 1982-04-30 1986-07-28 Medinvent Sa Anordning for implantation av en rorformig protes
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
JPS59135272A (ja) 1983-01-21 1984-08-03 Kuraray Co Ltd 接着剤
DE3323913C2 (de) 1983-07-02 1986-01-02 Th. Goldschmidt Ag, 4300 Essen Polyisobutylenbernsteinsäurehalbester, ihre Herstellung und ihre Verwendung zur Herstellung eines Klebemittels
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4778786A (en) 1985-04-03 1988-10-18 Minnetonka, Inc. Composition for transdermal drug delivery
DE3536077A1 (de) 1985-10-09 1987-04-09 Muehlbauer Ernst Kg Polymerisierbare saeure und saeurederivate enthaltende verbindungen, dieselben enthaltende mischungen und ihre verwendung
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US4917686A (en) 1985-12-16 1990-04-17 Colorado Biomedical, Inc. Antimicrobial device and method
IE63321B1 (en) 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
JPS62223112A (ja) 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
SE453258B (sv) 1986-04-21 1988-01-25 Medinvent Sa Elastisk, sjelvexpanderande protes samt forfarande for dess framstellning
US4895566A (en) 1986-07-25 1990-01-23 C. R. Bard, Inc. Coating medical devices with cationic antibiotics
US5015479A (en) 1987-02-02 1991-05-14 Seamus Mulligan Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine
US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
US5114719A (en) 1987-04-29 1992-05-19 Sabel Bernhard A Extended drug delivery of small, water-soluble molecules
US4846844A (en) 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
US4886062A (en) 1987-10-19 1989-12-12 Medtronic, Inc. Intravascular radially expandable stent and method of implant
IT1215726B (it) 1988-01-18 1990-02-22 Alfa Wassermann Spa Formulazioni galeniche a cessione programmata.
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5268182A (en) 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5169642A (en) 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5165952A (en) 1989-01-18 1992-11-24 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5013306A (en) 1989-01-18 1991-05-07 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5602197A (en) 1989-05-30 1997-02-11 Corning Incorporated Reversible polymer gel binders for powder forming
JPH0366384A (ja) 1989-08-04 1991-03-22 Senjiyu Seiyaku Kk 生理活性物質放出制御システム
US5525348A (en) 1989-11-02 1996-06-11 Sts Biopolymers, Inc. Coating compositions comprising pharmaceutical agents
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5270358A (en) 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
DE59104822D1 (de) 1990-04-26 1995-04-06 Wacker Chemie Gmbh Organo(poly)siloxane mit organyloxy- und hydrogengruppen aufweisenden, endständigen siloxaneinheiten.
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
AU8050791A (en) 1990-06-20 1992-01-07 Advanced Polymer Systems Inc. Compositions and methods for the controlled release of soluble active substances
JP2559528B2 (ja) 1990-08-29 1996-12-04 株式会社日立製作所 光露光装置
AU1579092A (en) 1991-02-27 1992-10-06 Nova Pharmaceutical Corporation Anti-infective and anti-inflammatory releasing systems for medical devices
WO1993000873A1 (en) 1991-07-03 1993-01-21 Sano Corporation Composition and method for transdermal delivery of diclofenac
FR2699406B1 (fr) * 1992-12-21 1995-03-10 Commissariat Energie Atomique Films à base de copolymères, leurs applications dans des systèmes transdermiques et leurs procédés de préparation.
AU673878B2 (en) 1993-01-19 1996-11-28 Schneider (Usa) Inc. Clad composite stent
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US5769796A (en) 1993-05-11 1998-06-23 Target Therapeutics, Inc. Super-elastic composite guidewire
US5749837A (en) 1993-05-11 1998-05-12 Target Therapeutics, Inc. Enhanced lubricity guidewire
US5443455A (en) 1993-07-27 1995-08-22 Target Therapeutics, Inc. Guidewire and method of pretreating metal surfaces for subsequent polymer coating
US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5689641A (en) 1993-10-01 1997-11-18 Vicor, Inc. Multimedia collaboration system arrangement for routing compressed AV signal through a participant site without decompressing the AV signal
US5554147A (en) 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US5965505A (en) 1994-04-13 1999-10-12 The Procter & Gamble Company Detergents containing a heavy metal sequestrant and a delayed release peroxyacid bleach system
US5603955A (en) 1994-07-18 1997-02-18 University Of Cincinnati Enhanced loading of solutes into polymer gels
CN1169112A (zh) 1994-12-06 1997-12-31 普罗克特和甘保尔公司 保存稳定的,含有胶凝聚合物、脂类和脂肪酸乙二醇酯晶体的洁肤液
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5702717A (en) 1995-10-25 1997-12-30 Macromed, Inc. Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
US5739210A (en) * 1995-11-03 1998-04-14 Michigan State University Polymers comprising reversible hydrophobic functionalities
US5756145A (en) 1995-11-08 1998-05-26 Baylor College Of Medicine Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor
US5939090A (en) 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
US5997517A (en) 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US6004573A (en) 1997-10-03 1999-12-21 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6465525B1 (en) 1998-03-18 2002-10-15 Surmodics, Inc. Latent reactive blood compatible agents
US6007833A (en) * 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
AU770404B2 (en) 1999-09-22 2004-02-19 Surmodics, Inc. Water-soluble coating agents bearing initiator groups and coating process
EP1309360B1 (de) 2000-08-15 2006-04-19 SurModics, Inc. Matrix zur aufnahme von arzneimitteln

Also Published As

Publication number Publication date
AU2001281304B2 (en) 2006-05-25
AU8130401A (en) 2002-02-25
US20020041899A1 (en) 2002-04-11
CA2419379A1 (en) 2002-02-21
ATE323517T1 (de) 2006-05-15
US7794751B2 (en) 2010-09-14
US7056533B2 (en) 2006-06-06
DE60118933T2 (de) 2006-11-30
MXPA03001406A (es) 2004-05-04
EP1309360B1 (de) 2006-04-19
WO2002013871A3 (en) 2002-05-30
JP2004520088A (ja) 2004-07-08
WO2002013871A2 (en) 2002-02-21
US20060165751A1 (en) 2006-07-27
CA2419379C (en) 2011-10-11
EP1309360A2 (de) 2003-05-14

Similar Documents

Publication Publication Date Title
DE60118933D1 (de) Matrix zur aufnahme von arzneimitteln
TW200618830A (en) Micorprojection apparatus and system with low infection potential
ATE474563T1 (de) Hydrogelzusammensetzung zur transdermalen arzneistoffabgabe
DE60023520D1 (de) Flüssiges hochvisköses system mit gesteuerter freisetzung und medizinische oder chirurgische vorrichtung
DK0975367T3 (da) Forbedret afgivelse af lægemidler til slimhindeoverflader
DE602005011653D1 (de) Medizinprodukt mit gewebeabhängiger arzneimittelelution
MD20020072A (en) Combination of antibiotic(s) - polymer and utilization there of
ATE374597T1 (de) Mikrokugeln zur aktiven embolisierung
ATE206041T1 (de) Polyether-blockcopolymer micellare zusammensetzungen zur zielgerichteten verabreichung biologischer stoffe
TW200517157A (en) Apparatus and method for enhancing transdermal drug delivery
DE69833000D1 (de) Biologische kleber und verfahren zur topischen verabreichung von wirkstoffen
PT737066E (pt) Dispositivo transdermico contendo polivinilpirrolidona como potenciador de solubilidade
TW200517156A (en) Pretreatment method and system for enhancing transdermal drug delivery
MXPA02011099A (es) Dispositivos de suministro para tratamiento de enfermedades vasculares.
ID27503A (id) Tts yang mengandung antioksidan
RU2004131866A (ru) Форма для трансэпикутального введения для лечения синдрома усталых ног
TW200514590A (en) Hydrophilic adhesives for delivery of herbal medicines
DK1345595T3 (da) Ionstyrke-uafhængig farmaceutisk formulering med depotfrigivelse
KR20170040767A (ko) 용해성 마이크로니들 마스크 키트
BR0100564A (pt) Estrutura compósita com matriz adesiva,contendo um ou vários ativos
DE60101206D1 (de) Transdermale verabreichung von lasofoxifen
UA83036C2 (ru) Фармацевтическая композиция в виде гидрогеля для трансдермального введения в организм действующих веществ
CO5011042A1 (es) Uso de una oxazolidinona para la fabricacion de un medicamento para administracion topica
DK1150981T3 (da) Terapeutisk necleosidforbindelse
GEP20002177B (en) Ointment “Levaskani” for Treatment of Wounds and Burns

Legal Events

Date Code Title Description
8364 No opposition during term of opposition