DE60117801D1 - Pharmazeutische zusammensetzung mit gesteuerter freigabe und verzögerter absorption - Google Patents
Pharmazeutische zusammensetzung mit gesteuerter freigabe und verzögerter absorptionInfo
- Publication number
- DE60117801D1 DE60117801D1 DE60117801T DE60117801T DE60117801D1 DE 60117801 D1 DE60117801 D1 DE 60117801D1 DE 60117801 T DE60117801 T DE 60117801T DE 60117801 T DE60117801 T DE 60117801T DE 60117801 D1 DE60117801 D1 DE 60117801D1
- Authority
- DE
- Germany
- Prior art keywords
- active principle
- controlled release
- forming
- polymer
- microcapsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0009047A FR2811571B1 (fr) | 2000-07-11 | 2000-07-11 | Composition pharmaceutique orale, permettant la liberation controlee et l'absorption prolongee d'un principe actif |
FR0009047 | 2000-07-11 | ||
PCT/FR2001/002224 WO2002003964A1 (fr) | 2000-07-11 | 2001-07-10 | Composition pharmaceutique orale a liberation controlee et a absorption prolongee |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60117801D1 true DE60117801D1 (de) | 2006-05-04 |
DE60117801T2 DE60117801T2 (de) | 2006-11-23 |
Family
ID=8852353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60117801T Expired - Lifetime DE60117801T2 (de) | 2000-07-11 | 2001-07-10 | Pharmazeutische zusammensetzung mit gesteuerter freigabe und verzögerter absorption |
Country Status (13)
Country | Link |
---|---|
US (2) | US20040022849A1 (de) |
EP (1) | EP1299090B1 (de) |
JP (1) | JP2004502723A (de) |
AT (1) | ATE319431T1 (de) |
AU (1) | AU2001277570A1 (de) |
BR (1) | BR0112532A (de) |
CA (1) | CA2415378C (de) |
DE (1) | DE60117801T2 (de) |
ES (1) | ES2260253T3 (de) |
FR (1) | FR2811571B1 (de) |
IL (1) | IL153086A0 (de) |
WO (1) | WO2002003964A1 (de) |
ZA (1) | ZA200209525B (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2816840B1 (fr) * | 2000-11-17 | 2004-04-09 | Flamel Tech Sa | Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation |
JP3834215B2 (ja) | 2001-09-07 | 2006-10-18 | アグリテクノ矢崎株式会社 | ゲル被覆種子 |
FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
EP1492511B3 (de) | 2002-04-09 | 2012-05-02 | Flamel Technologies | Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen |
IL164221A0 (en) | 2002-04-09 | 2005-12-18 | Flamel Tech Sa | Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim |
US7670623B2 (en) * | 2002-05-31 | 2010-03-02 | Materials Modification, Inc. | Hemostatic composition |
WO2003105809A1 (en) | 2002-06-17 | 2003-12-24 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
US8268352B2 (en) * | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US7985422B2 (en) | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
US7560160B2 (en) * | 2002-11-25 | 2009-07-14 | Materials Modification, Inc. | Multifunctional particulate material, fluid, and composition |
US20040265372A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
WO2005065639A2 (en) * | 2003-11-21 | 2005-07-21 | Torrent Pharmaceuticals Limited | Novel pharmaceutical compositions |
US8241670B2 (en) * | 2004-04-15 | 2012-08-14 | Chiasma Inc. | Compositions capable of facilitating penetration across a biological barrier |
US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
FR2889810A1 (fr) * | 2005-05-24 | 2007-02-23 | Flamel Technologies Sa | Forme medicamenteuse orale, microparticulaire, anti-mesurage |
DE102005006539A1 (de) * | 2005-02-11 | 2006-08-24 | Merck Patent Gmbh | Biguanid enthaltende Zusammensetzungen |
WO2006133733A1 (en) | 2005-06-13 | 2006-12-21 | Flamel Technologies | Oral dosage form comprising an antimisuse system |
FR2891459B1 (fr) * | 2005-09-30 | 2007-12-28 | Flamel Technologies Sa | Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant |
US8652529B2 (en) | 2005-11-10 | 2014-02-18 | Flamel Technologies | Anti-misuse microparticulate oral pharmaceutical form |
FR2892937B1 (fr) * | 2005-11-10 | 2013-04-05 | Flamel Tech Sa | Forme pharmaceutique orale microparticulaire anti-mesusage |
US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
AU2007205996A1 (en) * | 2006-01-10 | 2007-07-26 | Pipex, Inc. | Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases |
US20070264346A1 (en) * | 2006-02-16 | 2007-11-15 | Flamel Technologies | Multimicroparticulate pharmaceutical forms for oral administration |
US9023400B2 (en) * | 2006-05-24 | 2015-05-05 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
JP4741991B2 (ja) | 2006-07-14 | 2011-08-10 | 株式会社日立製作所 | シリアアライザ/デシリアライザ方式の転送装置 |
EP3210474B1 (de) | 2008-09-17 | 2020-11-18 | Chiasma, Inc. | Pharmazeutische zusammensetzungen mit polypeptiden und zugehörige abgabeverfahren |
EP2521570A4 (de) * | 2009-12-29 | 2015-05-13 | Impax Laboratories Inc | Feste gastroretentive orale dosierungsformen mit quellfähigem hydrophilem polymer |
CN103037870B (zh) | 2010-05-12 | 2016-05-25 | 斯派克托姆制药公司 | 碱式碳酸镧、碳酸氧镧及其制造方法和用途 |
EP2872121B1 (de) | 2012-07-12 | 2018-09-05 | SpecGx LLC | Missbrauchssichere pharmazeutische zusammensetzungen mit verzögerter freisetzung |
US10842802B2 (en) | 2013-03-15 | 2020-11-24 | Medicis Pharmaceutical Corporation | Controlled release pharmaceutical dosage forms |
US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
MA41462A (fr) | 2015-02-03 | 2021-05-12 | Chiasma Inc | Méthode de traitement de maladies |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
CA3127871A1 (en) | 2019-03-01 | 2020-09-10 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
CN110354090B (zh) * | 2019-07-29 | 2021-10-01 | 石药集团欧意药业有限公司 | 一种盐酸二甲双胍缓释片及其制备方法 |
CN111202718A (zh) * | 2020-02-25 | 2020-05-29 | 北京鑫开元医药科技有限公司 | 一种盐酸雷尼替丁胶囊及其制备方法 |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6248618A (ja) * | 1985-08-27 | 1987-03-03 | Zeria Shinyaku Kogyo Kk | 徐放性製剤およびその製造法 |
US5268182A (en) * | 1988-06-24 | 1993-12-07 | Abbott Laboratories | Sustained-release drug dosage units of terazosin |
CA2007181C (en) | 1989-01-06 | 1998-11-24 | Angelo Mario Morella | Sustained release pharmaceutical composition |
IT1250421B (it) | 1991-05-30 | 1995-04-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato con proprieta' bio-adesive. |
FR2704146B1 (fr) * | 1993-04-19 | 1995-07-13 | Cripdom | Microcapsules d'acide acétylsalicylique à libération contrôlée. |
SI9520049A (en) * | 1994-05-06 | 1997-12-31 | Pfizer | Controlled-release dosage forms of azithromycin |
DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
FR2725623A1 (fr) * | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
US5858398A (en) | 1994-11-03 | 1999-01-12 | Isomed Inc. | Microparticular pharmaceutical compositions |
ID26082A (id) * | 1998-03-19 | 2000-11-23 | Briston Myers Squib Company | Sistem pengiriman lepas terkendali dwifasa untuk zat-zat farmasi kelarutan tinggi dan metodenya |
US6099859A (en) | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
US5945123A (en) * | 1998-04-02 | 1999-08-31 | K-V Pharmaceutical Company | Maximizing effectiveness of substances used to improve health and well being |
US6499158B1 (en) | 2000-10-30 | 2002-12-31 | Steris, Inc. | Surgical table top and accessory clamp used thereon |
-
2000
- 2000-07-11 FR FR0009047A patent/FR2811571B1/fr not_active Expired - Fee Related
-
2001
- 2001-07-10 BR BR0112532-0A patent/BR0112532A/pt not_active IP Right Cessation
- 2001-07-10 ES ES01955397T patent/ES2260253T3/es not_active Expired - Lifetime
- 2001-07-10 IL IL15308601A patent/IL153086A0/xx unknown
- 2001-07-10 CA CA2415378A patent/CA2415378C/fr not_active Expired - Fee Related
- 2001-07-10 US US10/332,463 patent/US20040022849A1/en not_active Abandoned
- 2001-07-10 AT AT01955397T patent/ATE319431T1/de not_active IP Right Cessation
- 2001-07-10 WO PCT/FR2001/002224 patent/WO2002003964A1/fr active IP Right Grant
- 2001-07-10 DE DE60117801T patent/DE60117801T2/de not_active Expired - Lifetime
- 2001-07-10 AU AU2001277570A patent/AU2001277570A1/en not_active Abandoned
- 2001-07-10 JP JP2002508419A patent/JP2004502723A/ja active Pending
- 2001-07-10 EP EP01955397A patent/EP1299090B1/de not_active Expired - Lifetime
-
2002
- 2002-11-22 ZA ZA200209525A patent/ZA200209525B/en unknown
-
2007
- 2007-03-21 US US11/723,553 patent/US7879362B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2415378C (fr) | 2010-03-16 |
ES2260253T3 (es) | 2006-11-01 |
IL153086A0 (en) | 2003-06-24 |
WO2002003964A1 (fr) | 2002-01-17 |
BR0112532A (pt) | 2003-07-29 |
DE60117801T2 (de) | 2006-11-23 |
ZA200209525B (en) | 2003-11-24 |
AU2001277570A1 (en) | 2002-01-21 |
EP1299090A1 (de) | 2003-04-09 |
US20040022849A1 (en) | 2004-02-05 |
US20070207214A1 (en) | 2007-09-06 |
ATE319431T1 (de) | 2006-03-15 |
JP2004502723A (ja) | 2004-01-29 |
US7879362B2 (en) | 2011-02-01 |
FR2811571A1 (fr) | 2002-01-18 |
FR2811571B1 (fr) | 2002-10-11 |
CA2415378A1 (fr) | 2002-01-17 |
EP1299090B1 (de) | 2006-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |