DE60116764D1 - Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum - Google Patents

Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum

Info

Publication number
DE60116764D1
DE60116764D1 DE60116764T DE60116764T DE60116764D1 DE 60116764 D1 DE60116764 D1 DE 60116764D1 DE 60116764 T DE60116764 T DE 60116764T DE 60116764 T DE60116764 T DE 60116764T DE 60116764 D1 DE60116764 D1 DE 60116764D1
Authority
DE
Germany
Prior art keywords
skin
sampling
monitoring
substance
penetrationability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60116764T
Other languages
English (en)
Other versions
DE60116764T2 (de
Inventor
J Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE60116764D1 publication Critical patent/DE60116764D1/de
Application granted granted Critical
Publication of DE60116764T2 publication Critical patent/DE60116764T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/422Desensitising skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
DE60116764T 2000-06-06 2001-06-06 Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum Expired - Lifetime DE60116764T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US588767 2000-06-06
US09/588,767 US6537242B1 (en) 2000-06-06 2000-06-06 Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
PCT/US2001/018198 WO2001093931A1 (en) 2000-06-06 2001-06-06 Method and apparatus for enhancing penetration of a puncturing member into the intradermal space

Publications (2)

Publication Number Publication Date
DE60116764D1 true DE60116764D1 (de) 2006-04-06
DE60116764T2 DE60116764T2 (de) 2006-11-02

Family

ID=24355216

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60116764T Expired - Lifetime DE60116764T2 (de) 2000-06-06 2001-06-06 Vorrichtung zum verbessern der penetrierbarkeit eines punktierelementes in den intradermalen raum

Country Status (8)

Country Link
US (1) US6537242B1 (de)
EP (1) EP1289588B1 (de)
JP (1) JP4746818B2 (de)
AT (1) ATE315944T1 (de)
AU (1) AU2001275260A1 (de)
DE (1) DE60116764T2 (de)
ES (1) ES2254435T3 (de)
WO (1) WO2001093931A1 (de)

Families Citing this family (320)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US20020198509A1 (en) * 1999-10-14 2002-12-26 Mikszta John A. Intradermal delivery of vaccines and gene therapeutic agents via microcannula
US8465468B1 (en) * 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
DE60020159T2 (de) * 1999-12-10 2005-10-06 Alza Corp., Mountain View Hautbehandlungsvorrichtung zur verlängerten transdermalen verabreichung von medikamenten
US9717451B2 (en) * 2000-06-08 2017-08-01 Becton, Dickinson And Company Device for withdrawing or administering a substance and method of manufacturing a device
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6749575B2 (en) * 2001-08-20 2004-06-15 Alza Corporation Method for transdermal nucleic acid sampling
PT1341442E (pt) * 2000-10-13 2005-09-30 Alza Corp Aplicador de impacto com um conjunto de microlaminas
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
EP2085109A3 (de) * 2000-10-26 2009-09-02 Alza Corporation Transdermale Arzneimittelverabreichungsvorrichtungen mit beschichteten Mikrovorsprüngen
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
EP2554196B1 (de) * 2000-11-30 2018-10-17 Valeritas, Inc. Flüssigkeitsabgabe- und -messsysteme
EP1345646A2 (de) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Mikronadel-vorrichtungen und deren herstellung
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6752817B2 (en) * 2001-03-26 2004-06-22 Bayer Corporation Split pressure ring for lancing device and method of operation
CA2444391A1 (en) * 2001-04-13 2002-10-24 Becton Dickinson And Company Methods and devices for administration of substances into the intradermal layer of skin for systemic absorption
WO2002085447A2 (en) * 2001-04-20 2002-10-31 Alza Corporation Microprojection array having a beneficial agent containing coating
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
EP1404234B1 (de) 2001-06-12 2011-02-09 Pelikan Technologies Inc. Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
DE60234598D1 (de) 2001-06-12 2010-01-14 Pelikan Technologies Inc Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
WO2003022330A2 (en) * 2001-09-12 2003-03-20 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
ES2329781T3 (es) * 2002-02-04 2009-12-01 Becton, Dickinson And Company Dispositivo y metodo para suministrar o extraer una sustancia a traves de la piel.
EP1490147A2 (de) * 2002-03-04 2004-12-29 Nano Pass Technologies Ltd. Vorrichtungen und verfahren für den transport von flüssigkeit durch eine biologische barriere
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7811260B2 (en) 2002-05-31 2010-10-12 Vidacare Corporation Apparatus and method to inject fluids into bone marrow and other target sites
CA2485904C (en) 2002-05-31 2013-05-21 Vidacare Corporation Apparatus and method to access the bone marrow
US11337728B2 (en) 2002-05-31 2022-05-24 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
US8641715B2 (en) 2002-05-31 2014-02-04 Vidacare Corporation Manual intraosseous device
US8668698B2 (en) 2002-05-31 2014-03-11 Vidacare Corporation Assembly for coupling powered driver with intraosseous device
US10973545B2 (en) 2002-05-31 2021-04-13 Teleflex Life Sciences Limited Powered drivers, intraosseous devices and methods to access bone marrow
JP4460451B2 (ja) * 2002-08-29 2010-05-12 ベクトン・ディキンソン・アンド・カンパニー 回転マイクロ剥離面による物質送達
EP1539241A2 (de) * 2002-08-30 2005-06-15 Becton, Dickinson and Company Verfahren zur kontrolle der pharmakokinetik von immunomodulatorischen verbindungen
WO2004033021A1 (en) * 2002-10-07 2004-04-22 Biovalve Technologies, Inc. Microneedle array patch
EP1581116B1 (de) * 2002-12-30 2010-04-07 Roche Diagnostics GmbH Kapillarrohr-spitzen-design zur unterstützung des blutflusses
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7578954B2 (en) * 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
US9504477B2 (en) 2003-05-30 2016-11-29 Vidacare LLC Powered driver
EP1628567B1 (de) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Verfahren und vorrichtung zur injektion von flüssigkeit
DK1633235T3 (da) 2003-06-06 2014-08-18 Sanofi Aventis Deutschland Apparat til udtagelse af legemsvæskeprøver og detektering af analyt
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
CA2529048A1 (en) * 2003-06-13 2005-02-24 Becton, Dickinson And Company Improved intra-dermal delivery of biologically active agents
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CA2530531A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Formulations for coated microprojections containing non-volatile counterions
CA2536669A1 (en) * 2003-08-26 2005-03-17 Becton, Dickinson And Company Methods for intradermal delivery of therapeutics agents
EP1660149B1 (de) 2003-08-28 2018-03-07 Becton, Dickinson and Company Intradermale injektionsvorrichtung
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
EP1680014A4 (de) 2003-10-14 2009-01-21 Pelikan Technologies Inc Verfahren und gerät für eine variable anwenderschnittstelle
JP2007535337A (ja) * 2003-10-28 2007-12-06 アルザ・コーポレーシヨン 被覆された微小突起による治療用ペプチドおよびタンパクのポリマー接合体の送達
WO2005044333A2 (en) * 2003-10-31 2005-05-19 Alza Corporation Self-actuating applicator for microprojection array
EP1696983A2 (de) * 2003-12-18 2006-09-06 Novo Nordisk A/S Düsenvorrichtung mit hautdehnmittel
DE602004016687D1 (de) * 2003-12-22 2008-10-30 Paul Hadvary Dermal befestigte sensorvorrichtung
EP1706171A1 (de) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medizinprodukte und diese enthaltende sets
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
GB0402131D0 (en) * 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005091922A2 (en) * 2004-03-03 2005-10-06 Becton, Dickinson And Company Methods and devices for improving delivery of a substance to skin
US7377903B2 (en) * 2004-03-05 2008-05-27 Roche Diagnostics Operations, Inc. Split tip expression device
US20050203575A1 (en) * 2004-03-15 2005-09-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Skin microactivation system and method
WO2005094526A2 (en) * 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US7201723B2 (en) * 2004-03-25 2007-04-10 Roche Diagnostics Operations, Inc. Pulsating expression cap
BRPI0509806A (pt) * 2004-04-12 2007-09-18 Allergan Inc sistema de injeção em múltiplos locais
WO2005115360A2 (en) * 2004-05-11 2005-12-08 Becton, Dickinson And Company Formulations of anti-pain agents and methods of using the same
BRPI0509788A (pt) 2004-05-13 2007-10-23 Alza Corp aparato e método para liberação transdérmica de agentes de hormÈnio paratireóides
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US7076987B2 (en) * 2004-08-05 2006-07-18 Becton, Dickinson And Company Method of producing tapered or pointed cannula
KR20070065333A (ko) * 2004-09-16 2007-06-22 쥬바 메디컬, 인코포레이티드 조직 확장 기구
US20060058892A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
US7641688B2 (en) 2004-09-16 2010-01-05 Evera Medical, Inc. Tissue augmentation device
US20060058891A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Transformable tissue bulking device
US7244270B2 (en) * 2004-09-16 2007-07-17 Evera Medical Systems and devices for soft tissue augmentation
JP4927752B2 (ja) * 2004-11-18 2012-05-09 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイアプリケーターおよび保持装置
WO2006055799A1 (en) * 2004-11-18 2006-05-26 3M Innovative Properties Company Masking method for coating a microneedle array
AU2012201016B2 (en) * 2004-11-18 2012-10-11 3M Innovative Properties Company Low-profile microneedle array applicator
CA2587387C (en) 2004-11-18 2013-06-25 3M Innovative Properties Company Method of contact coating a microneedle array
KR20130026511A (ko) * 2004-11-18 2013-03-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US10207095B2 (en) 2004-12-14 2019-02-19 C. R. Bard, Inc. Fast clear port
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US10226207B2 (en) * 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
JP5301985B2 (ja) 2005-04-07 2013-09-25 スリーエム イノベイティブ プロパティズ カンパニー ツールフィードバック感知のためのシステム及び方法
EP1904158B1 (de) * 2005-06-24 2013-07-24 3M Innovative Properties Company Faltbares Pflaster mit Mikronadelnanordnung
JP5144510B2 (ja) * 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
US20070038148A1 (en) * 2005-08-11 2007-02-15 Joel Mechelke Sampling module for extracting interstitial fluid
US20090093737A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound apparatus with treatment lens
US7967763B2 (en) * 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
JP2007097980A (ja) * 2005-10-07 2007-04-19 Univ Kansai 穿刺デバイスおよびその製造方法
EP1785090A1 (de) * 2005-11-10 2007-05-16 F.Hoffmann-La Roche Ag Stechelement, Stechsystem und Verfahren zur Hautdetektion
US7842008B2 (en) * 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US20080200864A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080195036A1 (en) * 2005-12-02 2008-08-14 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
JP2010512170A (ja) * 2005-12-08 2010-04-22 ナノパス テクノロジーズ エルティディ. 薬剤投与器用マイクロ・ニードル・アダプタ
AU2006328853A1 (en) 2005-12-20 2007-06-28 Novo Nordisk A/S Skin retention device for a medical jet injection unit
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US20100168501A1 (en) * 2006-10-02 2010-07-01 Daniel Rogers Burnett Method and apparatus for magnetic induction therapy
US9610459B2 (en) * 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US8556828B2 (en) * 2006-02-09 2013-10-15 Panasonic Corporation Blood test device
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US20070276425A1 (en) * 2006-05-29 2007-11-29 Stanley Kim Painless Blood Sampling Lancet with Bundled Multiple Thin Needles
WO2007140381A2 (en) * 2006-05-29 2007-12-06 Stanley Kim Multiple needle system
JP2008022988A (ja) * 2006-07-19 2008-02-07 Ritsumeikan 採血装置
US8944069B2 (en) 2006-09-12 2015-02-03 Vidacare Corporation Assemblies for coupling intraosseous (IO) devices to powered drivers
ES2805203T3 (es) 2006-09-12 2021-02-11 Teleflex Medical Devices S A R L Aparato para biopsia y aspiración de médula ósea
WO2008042902A2 (en) * 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
KR20080051342A (ko) * 2006-12-05 2008-06-11 연세대학교 산학협력단 마이크로니들 기기 및 이의 응용방법
JP2008154849A (ja) * 2006-12-25 2008-07-10 Ritsumeikan 注入装置
WO2008091602A2 (en) * 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
KR20090128499A (ko) * 2007-03-19 2009-12-15 인슐린 메디컬 엘티디 약물 전달 장치
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
EP2131723B1 (de) * 2007-03-19 2013-07-24 Insuline Medical Ltd. Vorrichtung zur messung von substanzen
US20100286467A1 (en) * 2007-03-19 2010-11-11 Benny Pesach Device for drug delivery and associated connections thereto
US9114238B2 (en) 2007-04-16 2015-08-25 Corium International, Inc. Solvent-cast microprotrusion arrays containing active ingredient
JP5044334B2 (ja) * 2007-09-06 2012-10-10 株式会社ニコン 採液収容装置
JP5222512B2 (ja) * 2007-09-19 2013-06-26 凸版印刷株式会社 マイクロニードルチップ
US20090093723A1 (en) * 2007-10-05 2009-04-09 Cabochon Aesthetics, Inc. Ultrasound device including dispenser
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
WO2009079712A1 (en) 2007-12-24 2009-07-02 The University Of Queensland Coating method
JP5508285B2 (ja) 2008-01-04 2014-05-28 エッジ システムズ コーポレーション 皮膚を治療するための装置および方法
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
US20090198329A1 (en) 2008-02-01 2009-08-06 Kesten Randy J Breast implant with internal flow dampening
US20090198331A1 (en) * 2008-02-01 2009-08-06 Kesten Randy J Implantable prosthesis with open cell flow regulation
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
WO2009130926A1 (ja) * 2008-04-22 2009-10-29 南部化成株式会社 経皮投薬方法、ニードル形成体及び経皮投薬装置
WO2009136479A1 (ja) * 2008-05-09 2009-11-12 パナソニック株式会社 皮膚切開器具およびそれによって皮膚を切開する方法
JP4422791B2 (ja) 2008-05-13 2010-02-24 パナソニック株式会社 皮膚切開器具
US9066738B2 (en) * 2008-07-14 2015-06-30 Syneron Medical Ltd. Devices and methods for percutaneous energy delivery
US20100106063A1 (en) * 2008-10-29 2010-04-29 Cabochon Aesthetics, Inc. Ultrasound Enhancing Target for Treating Subcutaneous Tissue
CN102245137A (zh) 2008-11-07 2011-11-16 茵苏莱恩医药有限公司 用于药物递送的装置和方法
JP5713913B2 (ja) * 2008-11-07 2015-05-07 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company 薬剤の注射を容易にするシリンジ筐体
EP2355862A4 (de) 2008-12-09 2015-07-08 Becton Dickinson Co Zweikammer-arzneiausgabevorrichtung für hochdruckinjektionen
EP2355869B1 (de) 2008-12-09 2022-08-24 Becton, Dickinson and Company Mehrtakt-ausgabepumpmechanismus für eine arzneiverabreichungsvorrichtung für hochdruckinjektionen
JP5600115B2 (ja) 2008-12-09 2014-10-01 ベクトン・ディキンソン・アンド・カンパニー 高圧注入システムのためにレバーおよびギア力を増大させる薬剤供給システム
CA2746164C (en) 2008-12-09 2019-08-13 Becton, Dickinson And Company Open and closed valve medication delivery system for high pressure injections
KR101033513B1 (ko) * 2009-01-20 2011-05-09 (주)마이티시스템 미세바늘을 이용한 유용성분 피부전달용 용기
US9440024B2 (en) * 2009-01-27 2016-09-13 Becton, Dickinson And Company Infusion set with anesthetic compound
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8167280B2 (en) * 2009-03-23 2012-05-01 Cabochon Aesthetics, Inc. Bubble generator having disposable bubble cartridges
US20100256596A1 (en) * 2009-04-07 2010-10-07 Cabochon Aesthetics, Inc. Fiber growth promoting implants for reducing the appearance of cellulite
CA2759850C (en) * 2009-04-24 2019-10-22 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2451367B1 (de) 2009-07-08 2020-01-22 Edge Systems Corporation Vorrichtungen zur hautbehandlung mithilfe zeitgesteuert freigesetzter substanzen
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
WO2011016230A1 (ja) * 2009-08-07 2011-02-10 株式会社メドレックス 剣山型マイクロニードルのアプリケータデバイス
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
JP2011045565A (ja) * 2009-08-27 2011-03-10 Nanbu Plastics Co Ltd 薬液注入装置
EP2482724A2 (de) * 2009-09-30 2012-08-08 Dexcom, Inc. Transkutaner analytsensor
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス, インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
DE102009046581A1 (de) * 2009-11-10 2011-05-12 Robert Bosch Gmbh Herstellungsverfahren für eine poröse Mikronadelanordnung und entsprechende poröse Mikronadelanordnung und entsprechender Substratverbund
RU2539991C2 (ru) * 2009-12-16 2015-01-27 Кронтек Фарма Аб Впрыскивающие игла и устройство
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CA2801247C (en) * 2010-05-04 2018-09-04 Corium International, Inc. Applicators for microneedles
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
JP5770055B2 (ja) * 2010-09-29 2015-08-26 富士フイルム株式会社 針状アレイ経皮吸収シートの製造方法
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
US20130296791A1 (en) * 2011-01-18 2013-11-07 Michael Segev Medication delivery assembly
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
JP4923156B1 (ja) * 2011-05-24 2012-04-25 エム・エフ・ヴィ株式会社 塗布用具
WO2012166965A2 (en) * 2011-05-31 2012-12-06 Microlin, Llc An apparatus and method for dermal delivery
GB201109620D0 (en) * 2011-06-09 2011-07-20 Ardehali Massoud H Injection apparatus
WO2012170497A2 (en) * 2011-06-09 2012-12-13 3M Innovative Properties Company Microstructure device with removable microstructure patch
US20120316499A1 (en) * 2011-06-10 2012-12-13 Erich George Brehm Fluid Delivery System
CN103717249B (zh) 2011-06-15 2017-03-22 克洛恩泰克制药股份公司 注射针和装置
US9730729B2 (en) 2011-07-11 2017-08-15 Teleflex Medical Devices S.A R.L. Sternal locators and associated systems and methods
WO2013046868A1 (ja) * 2011-09-29 2013-04-04 テルモ株式会社 シリンジ
AU2012323782B2 (en) 2011-10-12 2017-04-06 Vaxxas Pty Limited Delivery device
EP2589401A1 (de) * 2011-11-04 2013-05-08 Fiderm S.r.l. (Ricerca e Technogie in Scienze Dermatologiche) Vorrichtung zur Steuerung der Tiefe und zur Reduzierung des Schmerzes von Injektionen
WO2013065814A1 (ja) * 2011-11-04 2013-05-10 ニプロ株式会社 注射針
US10058657B2 (en) * 2011-11-07 2018-08-28 Eli Lilly And Company Injection devices with ergonomic enhancements
CA2859387A1 (en) 2011-12-16 2013-06-20 Moderna Therapeutics, Inc. Modified nucleoside, nucleotide, and nucleic acid compositions
WO2013151766A1 (en) * 2012-04-02 2013-10-10 Medtronic, Inc. Therapy for kidney disease and/or heart failure by intradermal infusion
EP3563772B1 (de) * 2012-08-14 2022-01-12 The General Hospital Corporation Vorrichtung zur gewebeableitung
CN103673821A (zh) * 2012-09-03 2014-03-26 致茂电子(苏州)有限公司 探针压缩行程量测方法与相关的电路测试系统
US9782574B2 (en) 2012-10-10 2017-10-10 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
US20140107450A1 (en) 2012-10-12 2014-04-17 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140213866A1 (en) 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
SG11201502146QA (en) * 2012-10-19 2015-05-28 Amgen Inc Improved autoinjector
JP6144355B2 (ja) 2012-11-26 2017-06-07 モデルナティエックス インコーポレイテッドModernaTX,Inc. 化学修飾mRNA
ES2743404T3 (es) 2012-12-21 2020-02-19 Corium Inc Matriz para suministro de agente terapéutico y método de fabricación
US20150352295A1 (en) * 2013-01-08 2015-12-10 3M Innovative Properties Company Application For Applying A Microneedle Device To Skin
WO2014113089A2 (en) 2013-01-17 2014-07-24 Moderna Therapeutics, Inc. Signal-sensor polynucleotides for the alteration of cellular phenotypes
EP2957315B1 (de) 2013-02-13 2019-11-13 Hisamitsu Pharmaceutical Co., Inc. Mikronadelarray
WO2014130359A1 (en) 2013-02-20 2014-08-28 Cytrellis Biosystems, Inc. Methods and devices for skin tightening
CA2901568C (en) * 2013-02-28 2021-02-16 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery device
EP2968887B1 (de) 2013-03-12 2022-05-04 Corium, Inc. Mikroprojektionsapplikatoren
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CA2903459C (en) 2013-03-15 2024-02-20 Corium International, Inc. Multiple impact microprojection applicators and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
EP2968118B1 (de) 2013-03-15 2022-02-09 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur verwendung
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
EP2967633B1 (de) 2013-03-15 2018-04-25 Edge Systems LLC Vorrichtungen zur hautbehandlung
CA2909263C (en) 2013-04-15 2020-01-28 Becton, Dickinson And Company Biological fluid sampling transfer device and biological fluid separation and testing system
GB201307262D0 (en) 2013-04-23 2013-05-29 Chowdhury Dewan F H Device for containment and release of drug formulation
US9474849B2 (en) * 2013-06-07 2016-10-25 John Richard Parker Apparatus and method for reducing incidence of tick borne infections
US20150182703A1 (en) * 2013-12-02 2015-07-02 Biltmore Technologies, Inc. Nanofluidic delivery system
DE102013021058B4 (de) 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Vorrichtung zur Applizierung eines Nadelarrays auf biologischem Gewebe
JP6167048B2 (ja) * 2014-02-14 2017-07-19 株式会社ダイセル 無針注射器
US20150289788A1 (en) 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
EP3132822B1 (de) * 2014-04-14 2018-10-31 Toppan Printing Co., Ltd. Injektionsvorrichtung
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
EP2982302B1 (de) * 2014-08-05 2018-05-23 Roche Diabetes Care GmbH Medizinischer Applikator
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
JP2017533774A (ja) 2014-11-14 2017-11-16 サイトレリス バイオシステムズ,インコーポレーテッド 皮膚のアブレーションのためのデバイス及び方法
EP4324414A2 (de) 2014-12-23 2024-02-21 HydraFacial LLC Vorrichtungen und verfahren zur hautbehandlung mit einem rollball oder einem dochtelement
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP4218892A1 (de) 2015-02-02 2023-08-02 Vaxxas Pty Limited Mikroprojektionsarrayapplikator
CN106456954A (zh) * 2015-02-13 2017-02-22 美德阿利克斯株式会社 微针的穿刺装置及微针贴片的敷贴装置
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3319573A4 (de) 2015-07-08 2019-01-23 Edge Systems LLC Vorrichtungen, systeme und zusammensetzungen zur förderung des haarwachstums
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101711417B1 (ko) * 2015-10-14 2017-03-14 인하대학교 산학협력단 의료용 미소스테이플 삽입장치
US20170165434A1 (en) * 2015-12-10 2017-06-15 Xiamen Brana Design Co., Ltd. Multi-needle needle assembly
CN112089961B (zh) * 2015-12-21 2022-08-09 美德阿利克斯株式会社 微针贴片施用器及其壳体
US10500351B2 (en) 2016-02-12 2019-12-10 Shawn Michael Michels Aid for subcutaneous tissue injection and process of effecting the injection with the aid
US10220195B2 (en) * 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
JP6670207B2 (ja) * 2016-08-26 2020-03-18 日本発條株式会社 穿刺デバイス
US11464954B2 (en) 2016-09-21 2022-10-11 Cytrellis Biosystems, Inc. Devices and methods for cosmetic skin resurfacing
EP3554618B1 (de) 2016-12-16 2023-02-01 Sorrento Therapeutics, Inc. Flüssigkeitabgabevorrichtung zur behandlung von migräne oder clusterkopfschmerzen die eine mikronadeleinheit enthält
CN110300612B (zh) 2016-12-16 2022-04-22 索伦托治疗有限公司 具有控制器组件的流体递送装置及其使用方法
US11577023B2 (en) 2016-12-16 2023-02-14 Sorrento Therapeutics, Inc. Application device for a fluid delivery apparatus and method of use
US11219721B2 (en) * 2016-12-16 2022-01-11 Sorrento Therapeutics, Inc. Attachment band for a fluid delivery apparatus and method of use
CN113730789A (zh) 2016-12-16 2021-12-03 索伦托治疗有限公司 具有抽气机构的流体递送装置及其使用方法
EP3978063A1 (de) 2016-12-16 2022-04-06 Sorrento Therapeutics, Inc. Fluidausgabevorrichtung und verfahren zur montage
US10751484B2 (en) * 2017-01-26 2020-08-25 Allergan Industrie, Sas Needle array device
DK3606760T3 (da) 2017-03-31 2023-11-06 Vaxxas Pty Ltd Indretning og fremgangsmåde til belægning af overflader
US11039823B2 (en) 2017-05-03 2021-06-22 Z Surgical Llc Minimal-access percutaneous and self-retracting surgical system
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP3661587A4 (de) 2017-08-04 2021-06-09 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
CN111629772A (zh) * 2018-01-24 2020-09-04 考司美德制药株式会社 微针用张紧器具
EP3766537A4 (de) * 2018-03-13 2022-05-04 MEDRx Co., Ltd. Haftelement und mikronadelpflaster
JP2019170870A (ja) * 2018-03-29 2019-10-10 凸版印刷株式会社 マイクロニードル
JP1632957S (de) 2018-10-30 2019-06-03
US11369409B2 (en) * 2019-10-03 2022-06-28 Medline Industries, Lp System and method for fluid ingress control for a skin grafting system
WO2021081392A1 (en) * 2019-10-24 2021-04-29 Hopkins Janine Applicator device and methods of use
WO2021121589A1 (en) * 2019-12-18 2021-06-24 Uprax Microsolutions B.V. Applicators and methods for applying a microneedle patch to a skin of a subject, and microneedle patches
WO2021177317A1 (ja) * 2020-03-02 2021-09-10 シンクランド株式会社 マイクロニードルシート及び経皮吸収型薬剤
US20210353878A1 (en) * 2020-05-14 2021-11-18 Jonathan Robin Fugo Hypodermic device with an array of hypodermic needles
EP4161611A1 (de) * 2020-06-04 2023-04-12 SHL Medical AG Komponente einer medikamentenabgabevorrichtung oder zusatzmodul für eine medikamentenabgabevorrichtung
EP4223353A1 (de) 2020-09-30 2023-08-09 Shiseido Company, Ltd. Teil mit nadelförmigen vorsprüngen
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
WO2023168419A2 (en) * 2022-03-03 2023-09-07 Deka Products Limited Partnership Systems, methods, and apparatuses for medical agent administration
WO2023205341A1 (en) * 2022-04-22 2023-10-26 The Board Of Trustees Of The Leland Stanford Junior University Compliant polymeric structures having polymeric microneedles and methods for making and using same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1216813A (en) 1969-02-21 1970-12-23 Shozo Narusawa Transcutaneous injection device
CH582884A5 (de) * 1973-12-10 1976-12-15 Hoffmann La Roche
CA1272423A (en) * 1986-02-25 1990-08-07 Peter C. Lord Soft cannula subcutaneous injection set and method of making same
US4695273A (en) 1986-04-08 1987-09-22 I-Flow Corporation Multiple needle holder and subcutaneous multiple channel infusion port
FR2612401A1 (fr) 1987-03-16 1988-09-23 Denance Raymond Embout stabilisateur pour aiguille hypodermique comportant un moyen faisant office de bequille pour reguler la penetration en fonction de l'angle d'attaque de l'aiguille dans la peau
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
JPH0626570B2 (ja) * 1991-01-31 1994-04-13 参天製薬株式会社 二層式注射器の注射筒
JP3590805B2 (ja) * 1993-11-10 2004-11-17 株式会社ニコン 採血装置
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
SE9502285D0 (sv) 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
JP2718408B2 (ja) * 1995-09-20 1998-02-25 日本電気株式会社 浸出液吸引装置
EP0906062B1 (de) * 1996-05-17 2007-12-26 Roche Diagnostics Operations, Inc. körperflüssigkeitsentnahmevorrichtung
EP0914178B1 (de) 1996-06-18 2003-03-12 Alza Corporation Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
JP3382853B2 (ja) * 1998-04-09 2003-03-04 松下電器産業株式会社 体液検査装置
CA2229522A1 (en) 1998-04-15 1999-10-15 Thomas Randall Inkpen Needle aid
AU767122B2 (en) * 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
ATE462468T1 (de) 1999-06-04 2010-04-15 Georgia Tech Res Inst Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür

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ATE315944T1 (de) 2006-02-15
JP2003534881A (ja) 2003-11-25
EP1289588A1 (de) 2003-03-12
EP1289588B1 (de) 2006-01-18
WO2001093931A1 (en) 2001-12-13
DE60116764T2 (de) 2006-11-02
AU2001275260A1 (en) 2001-12-17
US6537242B1 (en) 2003-03-25
JP4746818B2 (ja) 2011-08-10
ES2254435T3 (es) 2006-06-16

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