DE60113121D1 - Herstellung von vernetzter hyaluronsäure und dessen hydrogel, die hergestellten produkte und deren verwendungen - Google Patents

Herstellung von vernetzter hyaluronsäure und dessen hydrogel, die hergestellten produkte und deren verwendungen

Info

Publication number
DE60113121D1
DE60113121D1 DE60113121T DE60113121T DE60113121D1 DE 60113121 D1 DE60113121 D1 DE 60113121D1 DE 60113121 T DE60113121 T DE 60113121T DE 60113121 T DE60113121 T DE 60113121T DE 60113121 D1 DE60113121 D1 DE 60113121D1
Authority
DE
Germany
Prior art keywords
hydrogel
networked
preparation
hyaluronic acid
products manufactured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60113121T
Other languages
English (en)
Other versions
DE60113121T2 (de
DE60113121T3 (de
Inventor
Estelle Piron
Raymonde Tholin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Industrie SAS
Original Assignee
LABORATOIRES D'ESTHETIQUE APPLIQUEE PARIS
D ESTHETIQUE APPLIQUEE PARIS L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8852712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60113121(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LABORATOIRES D'ESTHETIQUE APPLIQUEE PARIS, D ESTHETIQUE APPLIQUEE PARIS L filed Critical LABORATOIRES D'ESTHETIQUE APPLIQUEE PARIS
Application granted granted Critical
Publication of DE60113121D1 publication Critical patent/DE60113121D1/de
Publication of DE60113121T2 publication Critical patent/DE60113121T2/de
Publication of DE60113121T3 publication Critical patent/DE60113121T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
DE60113121T 2000-07-19 2001-07-16 Herstellung von vernetzter hyaluronsäure und dessen hydrogel, die hergestellten produkte und deren verwendungen Expired - Lifetime DE60113121T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0009497A FR2811996B1 (fr) 2000-07-19 2000-07-19 Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
FR0009497 2000-07-19
EP01954103A EP1303542B3 (de) 2000-07-19 2001-07-16 Herstellung von vernetzter hyaluronsäure und dessen hydrogel, die hergestellten produkte und deren verwendungen
PCT/FR2001/002300 WO2002006350A1 (fr) 2000-07-19 2001-07-16 Reticulation de polysaccharide(s), preparation d'hydrogel(s), polysaccharide(s) et hydrogel(s) obtenu(s), leurs utilisations.

Publications (3)

Publication Number Publication Date
DE60113121D1 true DE60113121D1 (de) 2005-10-06
DE60113121T2 DE60113121T2 (de) 2006-06-14
DE60113121T3 DE60113121T3 (de) 2012-11-22

Family

ID=8852712

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60113121T Expired - Lifetime DE60113121T3 (de) 2000-07-19 2001-07-16 Herstellung von vernetzter hyaluronsäure und dessen hydrogel, die hergestellten produkte und deren verwendungen

Country Status (7)

Country Link
US (1) US6921819B2 (de)
EP (1) EP1303542B3 (de)
CA (1) CA2416504C (de)
DE (1) DE60113121T3 (de)
ES (1) ES2250441T7 (de)
FR (1) FR2811996B1 (de)
WO (1) WO2002006350A1 (de)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
BR0306183A (pt) 2002-08-28 2004-10-19 Inamed Medical Products Corp Dispositivo de enfaixamento gástrico resistente à fadiga
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
CA2534033A1 (fr) * 2003-07-30 2005-02-10 Anteis S.A. Matrice complexe a usage biomedical
US8524213B2 (en) * 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
EP1706044B1 (de) 2004-01-23 2011-10-05 Allergan, Inc. Lösbar befestigbares, einteiliges, verstellbares magenband
FR2865737B1 (fr) * 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
FR2867073B1 (fr) * 2004-03-08 2006-05-05 Europlak Utilisation cosmetique de chitosane pour le traitement et le comblement des rides
ES2333024T3 (es) 2004-03-08 2010-02-16 Allergan Medical S.A. Sistema de cierre para organos tubulares.
EP1732635B1 (de) 2004-03-18 2011-07-27 Allergan, Inc. Vorrichtung zur volumeneinstellung intragastraler ballons
EP1750769B1 (de) * 2004-05-20 2013-01-23 Mentor Worldwide LLC Verfahren zur herstellung eines injizierbaren polymerhydrogels
US8251888B2 (en) 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
US20070116680A1 (en) * 2005-11-18 2007-05-24 Rensselaer Polytechnic Institute Stem cells within gel microenvironments
US7798954B2 (en) 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
CN101490140B (zh) * 2006-09-29 2012-03-28 株式会社日本触媒 用于生产吸水性树脂颗粒的方法
FR2909560B1 (fr) * 2006-12-06 2012-12-28 Fabre Pierre Dermo Cosmetique Gel d'acide hyaluronique pour injection intradermique
CA2687990A1 (en) * 2007-05-23 2008-12-04 Allergan, Inc. Cross-linked collagen and uses thereof
US8658148B2 (en) 2007-06-22 2014-02-25 Genzyme Corporation Chemically modified dendrimers
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
EP3498299A1 (de) 2007-11-16 2019-06-19 Aclaris Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von purpura
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
FR2924615B1 (fr) * 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
CN101502677B (zh) * 2008-02-04 2013-06-26 凌沛学 一种注射用交联透明质酸钠凝胶及其制备方法
US20090286289A1 (en) * 2008-03-10 2009-11-19 Pang Danny Z Production of Hyaluronate Unsaturated Disaccharides and its Application
ITMC20080129A1 (it) * 2008-07-08 2008-10-07 Phitogen Holding S P A Sintesi di acido ialuronico reticolato con inibitore della ialuronidasi microincapsulato.
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (de) 2008-09-02 2020-08-12 Tautona Group LP Stränge aus hyaluronsäure, verfahren zur herstellung davon und verwendungen davon
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
US8317677B2 (en) 2008-10-06 2012-11-27 Allergan, Inc. Mechanical gastric band with cushions
US20100185049A1 (en) 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
JP4885245B2 (ja) * 2009-01-15 2012-02-29 日本航空電子工業株式会社 Ｒｄコンバータ及び角度検出装置
WO2010115081A2 (en) 2009-04-02 2010-10-07 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
FR2945293B1 (fr) * 2009-05-11 2011-06-17 Teoxane Procede de preparation d'un gel reticule.
US20110171310A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US8283463B2 (en) * 2010-02-09 2012-10-09 Bausch & Lomb Incorporated Sterile hyaluronic acid solutions
US8758221B2 (en) 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
CA2792729C (en) 2010-03-12 2016-06-28 Allergan Industrie, Sas Fluid compositions for improving skin conditions
CA2794254C (en) 2010-03-22 2018-09-04 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
WO2011148116A2 (fr) 2010-05-27 2011-12-01 Laboratoire Idenov Acide hyaluronique modifie, procede de fabrication et utilisations
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
NZ610346A (en) 2010-11-08 2015-06-26 Allergan Ind Sas Hyaluronic acid based formulations
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
FR2968305B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
FR2968564B1 (fr) 2010-12-13 2013-06-21 Perouse Medical Dispositif medical destine a entrer en contact avec un tissu d'un patient et procede de fabrication associe.
EP3682911A1 (de) 2011-01-13 2020-07-22 Allergan, Inc. Stabile hydrogelzusammensetzungen mit additiven
EP2484387A1 (de) 2011-02-03 2012-08-08 Q-Med AB Hyaluronsäurezusammensetzung
CA2827615A1 (en) 2011-02-17 2012-08-23 Dennis E. Van Epps Compositions and improved soft tissue replacement methods
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9149422B2 (en) 2011-06-03 2015-10-06 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
ES2777176T3 (es) 2011-08-25 2020-08-04 Allergan Industrie Sas Composiciones de material de relleno dérmico que incluyen antioxidantes
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
KR20200116168A (ko) 2011-09-14 2020-10-08 알러간, 인코포레이티드 잔주름 치료를 위한 진피 필러 조성물
ITAN20110138A1 (it) 2011-10-12 2012-01-11 Regenyal Lab S R L Sintesi di un gel iniettabile multifasico a base di acido ialuronico monofasico libero e reticolato e di acido ialuronico bifasico associato con idrossiapatite con inibitore della ialuronidasi microincapsulato.
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
HUE050947T2 (hu) 2011-12-08 2021-01-28 Allergan Ind Sas Dermális töltõkészítmények
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
ITMI20120732A1 (it) 2012-05-03 2013-11-04 B S Srl Polisaccaridi reticolati a memoria di forma
KR102062420B1 (ko) 2012-07-18 2020-01-03 알러간 인더스트리 에스에이에스 피루베이트를 함유한 히알루론산 제제
CN102863631B (zh) * 2012-09-29 2013-11-13 杭州嘉伟生物制品有限公司 外科整形用组织填充剂交联透明质酸钠凝胶及其制备方法
ES2791180T3 (es) 2012-10-02 2020-11-03 Allergan Inc Hidrogeles de relleno dérmico con complejos de inclusión de vitamina A/ciclodextrina
WO2014055895A1 (en) 2012-10-05 2014-04-10 Allergan, Inc. Injectable device and method for sculpting, augmenting or correcting facial features such as the chin
KR101869988B1 (ko) * 2013-03-27 2018-06-21 주식회사 엘지화학 점탄성 히알루론산 가교물 제조용 조성물, 및 이를 이용하여 얻은 히알루론산 가교물
US20160082150A1 (en) * 2013-05-08 2016-03-24 Allergan Industrie S.A.S. Hyaluronic acid gels crosslinked by sodium trimetaphosphate
MX368941B (es) * 2013-06-28 2019-10-22 Galderma Sa Un procedimiento para preparar un producto de ácido hialurónico entrelazado.
KR20160140716A (ko) 2014-04-01 2016-12-07 클록스 테크놀로지스 인크. 조직 필러 조성물 및 사용 방법
WO2016005785A1 (en) 2014-07-11 2016-01-14 Allergan Industrie, Sas Hyaluronic acid gels crosslinked by sodium trimetaphosphate
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
DE102014015625A1 (de) 2014-10-16 2016-04-21 Gonzalo Urrutia Desmaison Lösungsvermittelnde Zusammenssetzungen
CN107427584A (zh) 2015-01-28 2017-12-01 阿勒根公司 关节脂肪垫制剂及其使用方法
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2017016917A1 (en) 2015-07-27 2017-02-02 Galderma Sa A process for efficient cross-linking of hyaluronic acid
KR20170060599A (ko) * 2015-11-24 2017-06-01 (주)한국비엠아이 히알루론산 유도체 및 dna 분획물이 포함된 히알루론산 주사용 조성물 및 이의 이용
US20200054786A1 (en) 2016-10-13 2020-02-20 Allergan, Inc. Coacervate hyaluronan hydrogels for dermal filler applications
IT201700008651A1 (it) 2017-01-26 2018-07-26 Beauty System Pharma Ltd Acido ialuronico reticolato con agenti reticolanti di tipo naturale o semisintetico
US20210402064A1 (en) 2018-05-09 2021-12-30 The Johns Hopkins University Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
CN112384258A (zh) 2018-05-09 2021-02-19 约翰·霍普金斯大学 用于细胞和组织递送的纳米纤维-水凝胶复合物
IT201900024208A1 (it) 2019-12-17 2021-06-17 Altergon Sa Miscele iniettabili di acido ialuronico per uso in dermoestetica

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA949965A (en) * 1971-12-03 1974-06-25 Robert H. Marchessault Method of preparing cross-linked starch and starch derivatives
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
US5783691A (en) * 1989-02-08 1998-07-21 Biomatrix, Inc. Crosslinked hyaluronate gels, their use and method for producing them
US6368356B1 (en) * 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
DE19800489A1 (de) * 1998-01-09 1999-07-15 Thomas Prof Dr Mang Polysaccharidhaltige Dichtungszusammensetzung

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DE60113121T2 (de) 2006-06-14
WO2002006350A1 (fr) 2002-01-24
ES2250441T3 (es) 2006-04-16
CA2416504A1 (en) 2002-01-24
DE60113121T3 (de) 2012-11-22
US6921819B2 (en) 2005-07-26
FR2811996B1 (fr) 2003-08-08
EP1303542B1 (de) 2005-08-31
CA2416504C (en) 2009-11-24
US20030148995A1 (en) 2003-08-07
FR2811996A1 (fr) 2002-01-25
ES2250441T7 (es) 2013-03-04
EP1303542B3 (de) 2012-07-04
EP1303542A1 (de) 2003-04-23

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