DE60108848D1 - Verfahren und vorrichtung zur ortung und konzentration von polaren analyten mittels eines elektrischen wechselfeldes - Google Patents

Verfahren und vorrichtung zur ortung und konzentration von polaren analyten mittels eines elektrischen wechselfeldes

Info

Publication number
DE60108848D1
DE60108848D1 DE60108848T DE60108848T DE60108848D1 DE 60108848 D1 DE60108848 D1 DE 60108848D1 DE 60108848 T DE60108848 T DE 60108848T DE 60108848 T DE60108848 T DE 60108848T DE 60108848 D1 DE60108848 D1 DE 60108848D1
Authority
DE
Germany
Prior art keywords
concentration
location
change area
electric change
polar analytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60108848T
Other languages
English (en)
Other versions
DE60108848T2 (de
Inventor
T Bryning
B Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of DE60108848D1 publication Critical patent/DE60108848D1/de
Publication of DE60108848T2 publication Critical patent/DE60108848T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/24Extraction; Separation; Purification by electrochemical means
    • C07K1/26Electrophoresis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44791Microapparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
DE60108848T 2000-03-10 2001-03-08 Verfahren und vorrichtung zur ortung und konzentration von polaren analyten mittels eines elektrischen wechselfeldes Expired - Lifetime DE60108848T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US522638 1983-08-11
US09/522,638 US6537433B1 (en) 2000-03-10 2000-03-10 Methods and apparatus for the location and concentration of polar analytes using an alternating electric field
PCT/US2001/007576 WO2001069230A2 (en) 2000-03-10 2001-03-08 Methods and apparatus for the location and concentration of polar analytes using an alternating electric field

Publications (2)

Publication Number Publication Date
DE60108848D1 true DE60108848D1 (de) 2005-03-17
DE60108848T2 DE60108848T2 (de) 2006-02-09

Family

ID=24081685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60108848T Expired - Lifetime DE60108848T2 (de) 2000-03-10 2001-03-08 Verfahren und vorrichtung zur ortung und konzentration von polaren analyten mittels eines elektrischen wechselfeldes

Country Status (8)

Country Link
US (4) US6537433B1 (de)
EP (1) EP1261863B1 (de)
JP (1) JP2003527601A (de)
AT (1) ATE289065T1 (de)
AU (1) AU2001245558A1 (de)
CA (1) CA2402189A1 (de)
DE (1) DE60108848T2 (de)
WO (1) WO2001069230A2 (de)

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WO2001069230A3 (en) 2002-06-20
US8083917B2 (en) 2011-12-27
EP1261863B1 (de) 2005-02-09
US20060081474A1 (en) 2006-04-20
US6969454B2 (en) 2005-11-29
JP2003527601A (ja) 2003-09-16
US6537433B1 (en) 2003-03-25
ATE289065T1 (de) 2005-02-15
DE60108848T2 (de) 2006-02-09
US7704363B2 (en) 2010-04-27
AU2001245558A1 (en) 2001-09-24
CA2402189A1 (en) 2001-09-20
EP1261863A2 (de) 2002-12-04
US20100203580A1 (en) 2010-08-12
US20030057094A1 (en) 2003-03-27

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