US6331313B1
(en)
*
|
1999-10-22 |
2001-12-18 |
Oculex Pharmaceticals, Inc. |
Controlled-release biocompatible ocular drug delivery implant devices and methods
|
US20050119737A1
(en)
*
|
2000-01-12 |
2005-06-02 |
Bene Eric A. |
Ocular implant and methods for making and using same
|
US20040208910A1
(en)
*
|
2000-04-26 |
2004-10-21 |
Control Delivery Systems, Inc. |
Sustained release device and method for ocular delivery of adrenergic agents
|
US20040175410A1
(en)
*
|
2000-04-26 |
2004-09-09 |
Control Delivery Systems, Inc. |
Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors
|
US6726918B1
(en)
|
2000-07-05 |
2004-04-27 |
Oculex Pharmaceuticals, Inc. |
Methods for treating inflammation-mediated conditions of the eye
|
DE60114229T2
(de)
|
2000-11-29 |
2006-07-06 |
Allergan, Inc., Irvine |
Verhinderung von transplantatabstossung im auge
|
WO2002100318A2
(en)
|
2001-06-12 |
2002-12-19 |
Johns Hopkins University School Of Medicine |
Reservoir device for intraocular drug delivery
|
US7556621B2
(en)
*
|
2001-06-29 |
2009-07-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Optically controlled microfluidic chip
|
EP1283025A1
(de)
*
|
2001-08-10 |
2003-02-12 |
Stöckert Instrumente GmbH |
Ballonokklusionsvorrichtung
|
US20040073175A1
(en)
*
|
2002-01-07 |
2004-04-15 |
Jacobson James D. |
Infusion system
|
FR2834446B1
(fr)
*
|
2002-01-08 |
2004-02-13 |
Ioltechnologie Production |
Clou meatique a expansion
|
CA2473355C
(en)
|
2002-01-18 |
2012-01-03 |
Michael E. Snyder |
Sustained release ophthalmological device and method of making and using the same
|
PL205443B1
(pl)
|
2002-03-11 |
2010-04-30 |
Alcon |
Wszczepiane urządzenie do podawania leku, zwłaszcza do oka
|
US20050048099A1
(en)
|
2003-01-09 |
2005-03-03 |
Allergan, Inc. |
Ocular implant made by a double extrusion process
|
JP2006516619A
(ja)
*
|
2003-01-24 |
2006-07-06 |
コントロール・デリバリー・システムズ・インコーポレイテッド |
炭酸脱水酵素阻害剤を眼へ輸送するために徐放性デバイス及び方法
|
WO2004066979A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Control Delivery Systems, Inc. |
Sustained release device and method for ocular delivery of adrenergic agents
|
US8404269B2
(en)
|
2003-04-11 |
2013-03-26 |
Michael Snyder |
Sustained release implantable eye device
|
WO2005023181A2
(en)
*
|
2003-08-22 |
2005-03-17 |
Vista Scientific |
Polymeric systems for controlled drug therapy
|
US20050197614A1
(en)
*
|
2004-03-04 |
2005-09-08 |
Wilson Pritchard |
Occlusive biomedical devices, punctum plugs, and methods of use thereof
|
US20050232972A1
(en)
*
|
2004-04-15 |
2005-10-20 |
Steven Odrich |
Drug delivery via punctal plug
|
US20050244469A1
(en)
|
2004-04-30 |
2005-11-03 |
Allergan, Inc. |
Extended therapeutic effect ocular implant treatments
|
EP3470108A1
(de)
*
|
2004-07-02 |
2019-04-17 |
Mati Therapeutics Inc. |
Vorrichtung zur abgabe eines behandlungsmittels im auge
|
US20060020253A1
(en)
*
|
2004-07-26 |
2006-01-26 |
Prescott Anthony D |
Implantable device having reservoir with controlled release of medication and method of manufacturing the same
|
WO2006014793A1
(en)
*
|
2004-07-26 |
2006-02-09 |
Clarity Corporation |
Implantable device having reservoir with controlled release of medication and method of manufacturing the same
|
US7117870B2
(en)
|
2004-07-26 |
2006-10-10 |
Clarity Corporation |
Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
|
WO2006031658A2
(en)
*
|
2004-09-10 |
2006-03-23 |
Allergan, Inc. |
Therapeutic lacrimal canalicular inserts and related methods
|
WO2006039459A1
(en)
*
|
2004-09-30 |
2006-04-13 |
Bausch & Lomb Incorporated |
Capsule for encasing tablets for surgical insertion into the human body
|
WO2006068898A1
(en)
*
|
2004-12-22 |
2006-06-29 |
Bausch & Lomb Incorporated |
Reusable drug delivery device
|
EP2182078B1
(de)
*
|
2005-09-01 |
2012-02-01 |
Bristol-Myers Squibb Company |
Biomarker und Verfahren zur Bestimmung der Empfindlichkeit gegen VEGFR2 modulator.
|
US20070212397A1
(en)
*
|
2005-09-15 |
2007-09-13 |
Roth Daniel B |
Pharmaceutical delivery device and method for providing ocular treatment
|
US7862532B2
(en)
*
|
2005-10-07 |
2011-01-04 |
Delta Life Sciences, Inc. |
Punctum plugs having insertion guides and strengthening beams
|
KR20090006153A
(ko)
|
2006-03-31 |
2009-01-14 |
큐엘티 플러그 딜리버리, 인코포레이티드 |
비루관계에 대한 약물 전달 방법, 구조, 및 조성물
|
US7981096B2
(en)
*
|
2006-05-12 |
2011-07-19 |
David Castillejos |
Optic nerve head implant and medication delivery system
|
US9173773B2
(en)
*
|
2006-06-21 |
2015-11-03 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs for the delivery of active agents
|
CN101505694B
(zh)
*
|
2006-06-21 |
2012-02-22 |
庄臣及庄臣视力保护公司 |
用于递送活性试剂的泪点塞
|
SG138567A1
(en)
*
|
2006-06-21 |
2008-01-28 |
Johnson & Johnson Vision Care |
Punctal plugs for the delivery of active agents
|
US9474645B2
(en)
*
|
2006-06-21 |
2016-10-25 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs for the delivery of active agents
|
US20080045911A1
(en)
*
|
2006-06-21 |
2008-02-21 |
Borgia Maureen J |
Punctal plugs for the delivery of active agents
|
WO2008024435A2
(en)
*
|
2006-08-23 |
2008-02-28 |
Vanderbilt University |
Dendritic molecular intracellular transporters and methods of making and using same
|
US20080086101A1
(en)
*
|
2006-08-25 |
2008-04-10 |
David Freilich |
Ophthalmic insert
|
KR20090102810A
(ko)
*
|
2006-12-26 |
2009-09-30 |
큐엘티 플러그 딜리버리, 인코포레이티드 |
시력 결함을 억제하기 위한 약물 전달 임플란트
|
UY30883A1
(es)
*
|
2007-01-31 |
2008-05-31 |
Alcon Res |
Tapones punctales y metodos de liberacion de agentes terapeuticos
|
US9125807B2
(en)
*
|
2007-07-09 |
2015-09-08 |
Incept Llc |
Adhesive hydrogels for ophthalmic drug delivery
|
MX2010002616A
(es)
*
|
2007-09-07 |
2010-08-04 |
Qlt Plug Delivery Inc |
Nucleos de farmaco para la liberacion sostenida de agentes terapeuticos.
|
WO2009035567A2
(en)
*
|
2007-09-07 |
2009-03-19 |
Qlt Plug Delivery, Inc |
Insertion and extraction tools for lacrimal implants
|
NZ583861A
(en)
|
2007-09-07 |
2012-08-31 |
Quadra Logic Tech Inc |
Lacrimal implants with an angled intersection between its sections so as to bias a portion of the body against the tissue surface
|
NZ583858A
(en)
*
|
2007-09-07 |
2012-08-31 |
Quadra Logic Tech Inc |
Lacrimal implant detection with detection device
|
US11254786B2
(en)
|
2007-11-05 |
2022-02-22 |
Vanderbilt University |
Multifunctional degradable nanoparticles with control over size and functionalities
|
US20110274620A1
(en)
*
|
2007-11-05 |
2011-11-10 |
Harth Eva M |
Multifunctional degradable nanoparticles with control over size and functionalities
|
ES2744834T3
(es)
|
2007-11-05 |
2020-02-26 |
Univ Vanderbilt |
Nanopartículas degradables multifuncionales con control sobre el tamaño y las funcionalidades
|
US20130142733A1
(en)
|
2007-11-05 |
2013-06-06 |
Vanderbilt University |
Multifunctional degradable nanoparticles with control over size and functionalities
|
WO2009079559A1
(en)
*
|
2007-12-17 |
2009-06-25 |
University Of Florida Research Foundation, Inc. |
Dry eye treatment by puncta plugs
|
WO2009097468A2
(en)
|
2008-01-29 |
2009-08-06 |
Kliman Gilbert H |
Drug delivery devices, kits and methods therefor
|
WO2009105178A2
(en)
*
|
2008-02-18 |
2009-08-27 |
Qlt Plug Delivery, Inc. |
Lacrimal implants and related methods
|
WO2009134371A2
(en)
|
2008-04-30 |
2009-11-05 |
Qlt Plug Delivery, Inc. |
Composite lacrimal insert and related methods
|
TWI542338B
(zh)
*
|
2008-05-07 |
2016-07-21 |
壯生和壯生視覺關懷公司 |
用於活性劑之控制釋放的眼用裝置
|
US9949942B2
(en)
*
|
2008-05-09 |
2018-04-24 |
Mati Therapeutics Inc. |
Sustained release delivery of active agents to treat glaucoma and ocular hypertension
|
US8894602B2
(en)
|
2010-09-17 |
2014-11-25 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs with directional release
|
US20090318549A1
(en)
*
|
2008-06-24 |
2009-12-24 |
Qlt Plug Delivery, Inc. |
Combination treatment of glaucoma
|
US20100158980A1
(en)
*
|
2008-12-18 |
2010-06-24 |
Casey Kopczynski |
Drug delivery devices for delivery of therapeutic agents
|
CA2747556A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Qlt Inc. |
Substance delivering punctum implants and methods
|
CN102341144B
(zh)
*
|
2009-01-23 |
2014-10-29 |
Qlt股份有限公司 |
一种或多种药剂的持续释放递送
|
SG173167A1
(en)
|
2009-01-29 |
2011-08-29 |
Forsight Labs Llc |
Posterior segment drug delivery
|
US8623395B2
(en)
|
2010-01-29 |
2014-01-07 |
Forsight Vision4, Inc. |
Implantable therapeutic device
|
EP2396070A4
(de)
|
2009-02-12 |
2012-09-19 |
Incept Llc |
Wirkstofffreisetzung mit hydrogel-plugs
|
WO2010096822A2
(en)
*
|
2009-02-23 |
2010-08-26 |
Qlt Plug Delivery, Inc. |
Lacrimal implants and related methods
|
WO2010101758A1
(en)
|
2009-03-03 |
2010-09-10 |
Alcon Research, Ltd. |
Peri-corneal drug delivery device
|
WO2010105130A2
(en)
*
|
2009-03-13 |
2010-09-16 |
Vista Scientific Llc |
Opthalmic drug delivery system and applications
|
TW201043211A
(en)
*
|
2009-03-31 |
2010-12-16 |
Johnson & Johnson Vision Care Inc |
Punctal plugs
|
TWI495459B
(zh)
*
|
2009-03-31 |
2015-08-11 |
Johnson & Johnson Vision Care |
淚管塞(二)
|
US9421127B2
(en)
|
2009-03-31 |
2016-08-23 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs
|
US10206813B2
(en)
|
2009-05-18 |
2019-02-19 |
Dose Medical Corporation |
Implants with controlled drug delivery features and methods of using same
|
US8808257B2
(en)
*
|
2009-08-31 |
2014-08-19 |
Johnson & Johnson Vision Care, Inc. |
Methods and apparatus for pulsatile release of medicaments from a punctal plug
|
WO2011094170A1
(en)
|
2010-01-27 |
2011-08-04 |
Alcon Research, Ltd. |
Pulsatile peri-corneal drug delivery device
|
US9259351B2
(en)
|
2010-03-29 |
2016-02-16 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs
|
US9259352B2
(en)
|
2010-03-29 |
2016-02-16 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs
|
JP2013526572A
(ja)
|
2010-05-17 |
2013-06-24 |
アエリエ・ファーマシューティカルズ・インコーポレーテッド |
眼治療薬の送達のための薬物送達装置
|
US20110301555A1
(en)
*
|
2010-06-03 |
2011-12-08 |
Gonzalez-Zugasti Javier P |
Porous matrix drug core for lacrimal insert device
|
HUE054113T2
(hu)
|
2010-08-05 |
2021-08-30 |
Forsight Vision4 Inc |
Injekciós készülék gyógyszerbejuttatáshoz
|
CA2807537C
(en)
|
2010-08-05 |
2018-09-18 |
Forsight Vision4, Inc. |
Combined drug delivery methods and apparatus
|
EP2600812B1
(de)
*
|
2010-08-05 |
2021-09-22 |
ForSight Vision4, Inc. |
Vorrichtung zur behandlung eines auges
|
US8821457B2
(en)
|
2010-09-08 |
2014-09-02 |
Johnson & Johnson Vision Care, Inc. |
Punctal plug containing drug formulation
|
US8591484B2
(en)
|
2010-09-15 |
2013-11-26 |
AlphaMed, Inc. |
Lacrimal punctum measurement and occlusion
|
CA2818612C
(en)
|
2010-11-19 |
2020-12-29 |
Forsight Vision4, Inc. |
Therapeutic agent formulations for implanted devices
|
US20120157938A1
(en)
|
2010-12-16 |
2012-06-21 |
Tokarski Jason M |
Punctal plug with drug core retention features
|
US9301874B2
(en)
|
2011-05-06 |
2016-04-05 |
Johnson & Johnson Vision Care, Inc. |
Punctal plugs for controlled release of therapeutic agents
|
EP4249059A3
(de)
|
2011-06-28 |
2023-11-29 |
ForSight Vision4, Inc. |
Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge
|
EP2739252A4
(de)
|
2011-08-05 |
2015-08-12 |
Forsight Vision4 Inc |
Abgabe kleiner moleküle über eine implantierbare therapeutische vorrichtung
|
WO2013030679A2
(en)
|
2011-08-29 |
2013-03-07 |
Qlt Inc. |
Sustained release delivery of active agents to treat glaucoma and ocular hypertension
|
US9974685B2
(en)
|
2011-08-29 |
2018-05-22 |
Mati Therapeutics |
Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
|
PL2755600T3
(pl)
|
2011-09-16 |
2021-09-20 |
Forsight Vision4, Inc. |
Urządzenie do wymiany płynów
|
US8721322B2
(en)
|
2011-11-30 |
2014-05-13 |
Johnson & Johnson Vision Care, Inc. |
Injection molding device and method
|
WO2013086015A1
(en)
|
2011-12-05 |
2013-06-13 |
Incept, Llc |
Medical organogel processes and compositions
|
US8911227B2
(en)
|
2012-01-11 |
2014-12-16 |
Johnson & Johnson Vision Care, Inc. |
Device for injection molding silicone rubber
|
US8808256B2
(en)
*
|
2012-01-16 |
2014-08-19 |
Johnson & Johnson Vision Care, Inc. |
Eye drug delivery system
|
US10010448B2
(en)
|
2012-02-03 |
2018-07-03 |
Forsight Vision4, Inc. |
Insertion and removal methods and apparatus for therapeutic devices
|
US20130220346A1
(en)
*
|
2012-02-28 |
2013-08-29 |
Victor Lust |
Balloon punctal plug
|
WO2014113384A2
(en)
|
2013-01-15 |
2014-07-24 |
The Regents Of The University Of Colorado, A Body Corporate |
Lacrimal system drug delivery device
|
US9968603B2
(en)
|
2013-03-14 |
2018-05-15 |
Forsight Vision4, Inc. |
Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
|
US10517759B2
(en)
|
2013-03-15 |
2019-12-31 |
Glaukos Corporation |
Glaucoma stent and methods thereof for glaucoma treatment
|
JP6385423B2
(ja)
|
2013-03-28 |
2018-09-05 |
フォーサイト・ビジョン フォー・インコーポレーテッド |
治療物質送達用の眼移植片
|
US20160302965A1
(en)
*
|
2013-12-06 |
2016-10-20 |
Forsight Vision4, Inc. |
Implantable therapeutic devices
|
JP6581194B2
(ja)
|
2014-07-15 |
2019-09-25 |
フォーサイト・ビジョン フォー・インコーポレーテッドForsight Vision4, Inc. |
眼用インプラント送達装置および方法
|
CN107106551A
(zh)
|
2014-08-08 |
2017-08-29 |
弗赛特影像4股份有限公司 |
受体酪氨酸激酶抑制剂的稳定且可溶的制剂和其制备方法
|
ES2756301T3
(es)
|
2014-08-19 |
2020-04-27 |
Univ California |
Implantes de administración localizada de fármacos y métodos de uso de los mismos
|
SG11201703726XA
(en)
|
2014-11-10 |
2017-06-29 |
Forsight Vision4 Inc |
Expandable drug delivery devices and method of use
|
EP3240510A4
(de)
|
2014-12-31 |
2018-09-19 |
Microoptx Inc. |
Verfahren und vorrichtungen zur behandlung von glaukom
|
WO2016187426A1
(en)
|
2015-05-19 |
2016-11-24 |
Amorphex Therapeutics Llc |
A device that delivers a sustained low-dose of a myopia-suppressing drug
|
CA2993182A1
(en)
|
2015-07-22 |
2017-01-26 |
Incept, Llc |
Coated punctal plug
|
WO2017040853A1
(en)
|
2015-09-02 |
2017-03-09 |
Glaukos Corporation |
Drug delivery implants with bi-directional delivery capacity
|
US11564833B2
(en)
*
|
2015-09-25 |
2023-01-31 |
Glaukos Corporation |
Punctal implants with controlled drug delivery features and methods of using same
|
EP3355983A4
(de)
*
|
2015-09-30 |
2019-06-26 |
Microoptx Inc. |
Vorrichtungen und verfahren zur behandlung des trockenen auges
|
WO2017062770A1
(en)
|
2015-10-08 |
2017-04-13 |
Silverberg Noah |
Punctal plug and bioadhesives
|
US10172740B2
(en)
|
2015-11-06 |
2019-01-08 |
David E Freilich |
Lacrimal stent
|
CN113069681B
(zh)
|
2015-11-20 |
2022-12-23 |
弗赛特影像4股份有限公司 |
制造用于缓释药物递送的治疗装置的方法
|
WO2017091404A1
(en)
|
2015-11-23 |
2017-06-01 |
The Regents Of The University Of Colorado, A Body Corporate |
Lacrimal system for drug delivery
|
CA3019822A1
(en)
|
2016-04-05 |
2017-10-12 |
Forsight Vision4, Inc. |
Implantable ocular drug delivery devices
|
CN115120405A
(zh)
|
2016-04-20 |
2022-09-30 |
多斯医学公司 |
生物可吸收眼部药物的递送装置
|
AU2017268379A1
(en)
*
|
2016-05-20 |
2018-12-06 |
The Regents Of The University Of Colorado, A Body Corporate |
Lacrimal drug delivery device
|
WO2019103906A1
(en)
|
2017-11-21 |
2019-05-31 |
Forsight Vision4, Inc. |
Fluid exchange apparatus for expandable port delivery system and methods of use
|
KR20220151622A
(ko)
|
2020-02-06 |
2022-11-15 |
오큘라 테라퓨틱스, 인코포레이티드 |
안질환 치료를 위한 조성물 및 방법
|
US11338119B2
(en)
|
2020-03-20 |
2022-05-24 |
The Regents Of The University Of California |
Implantable drug delivery devices for localized drug delivery
|
US11173291B2
(en)
|
2020-03-20 |
2021-11-16 |
The Regents Of The University Of California |
Implantable drug delivery devices for localized drug delivery
|
US11344526B2
(en)
|
2020-03-20 |
2022-05-31 |
The Regents Of The University Of California |
Implantable drug delivery devices for localized drug delivery
|
JP7378638B2
(ja)
|
2020-03-25 |
2023-11-13 |
オキュラ セラピューティクス,インコーポレイテッド |
チロシンキナーゼ阻害剤を含む眼内インプラント
|
AU2021358490A1
(en)
|
2020-10-05 |
2023-06-01 |
Max Biology Co. Ltd. |
Cannabinoid-containing compositions and use for treating and preventing diseases
|
KR20240015057A
(ko)
*
|
2021-01-15 |
2024-02-02 |
디퓨전 알엑스 인코포레이티드 |
치료제를 지속적이고 연속적으로 방출하는 조인트 임플란트
|
CN114652488A
(zh)
*
|
2022-03-22 |
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