DE60029413D1 - Enzymatische messung von mycophenolsäure - Google Patents
Enzymatische messung von mycophenolsäureInfo
- Publication number
- DE60029413D1 DE60029413D1 DE60029413T DE60029413T DE60029413D1 DE 60029413 D1 DE60029413 D1 DE 60029413D1 DE 60029413 T DE60029413 T DE 60029413T DE 60029413 T DE60029413 T DE 60029413T DE 60029413 D1 DE60029413 D1 DE 60029413D1
- Authority
- DE
- Germany
- Prior art keywords
- mycophenolic acid
- enzymatic measurement
- measurement
- present
- biological samples
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US328741 | 1994-10-27 | ||
US09/328,741 US6107052A (en) | 1999-06-09 | 1999-06-09 | Enzymatic measurement of mycophenolic acid |
PCT/US2000/012872 WO2000075363A2 (en) | 1999-06-09 | 2000-05-11 | Enzymatic measurement of mycophenolic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60029413D1 true DE60029413D1 (de) | 2006-08-31 |
DE60029413T2 DE60029413T2 (de) | 2007-02-22 |
Family
ID=23282234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60029413T Expired - Lifetime DE60029413T2 (de) | 1999-06-09 | 2000-05-11 | Enzymatische messung von mycophenolsäure |
Country Status (8)
Country | Link |
---|---|
US (1) | US6107052A (de) |
EP (1) | EP1112373B1 (de) |
JP (1) | JP3854864B2 (de) |
AT (1) | ATE333510T1 (de) |
CA (1) | CA2339821C (de) |
DE (1) | DE60029413T2 (de) |
ES (1) | ES2267541T3 (de) |
WO (1) | WO2000075363A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6811998B2 (en) * | 1999-06-25 | 2004-11-02 | Roche Diagnostics Operations, Inc. | Conjugates of uncompetitive inhibitors of inosine monophosphate dehydrogenase |
US6524808B1 (en) * | 1999-06-25 | 2003-02-25 | Roche Diagnostics Corporation | Enzyme inhibition immunoassay |
DE60140929D1 (de) * | 2000-11-14 | 2010-02-11 | Roche Diagnostics Gmbh | Immunoassay für HIV-Protease-Hemstoffe |
US20050125054A1 (en) * | 2000-12-22 | 2005-06-09 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
US7077859B2 (en) * | 2000-12-22 | 2006-07-18 | Avantec Vascular Corporation | Apparatus and methods for variably controlled substance delivery from implanted prostheses |
US20050203612A1 (en) * | 2000-12-22 | 2005-09-15 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
US20030050692A1 (en) * | 2000-12-22 | 2003-03-13 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
US6471980B2 (en) | 2000-12-22 | 2002-10-29 | Avantec Vascular Corporation | Intravascular delivery of mycophenolic acid |
US7083642B2 (en) * | 2000-12-22 | 2006-08-01 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
WO2003009778A2 (en) * | 2001-07-26 | 2003-02-06 | Avantec Vascular Corporation | Methods and devices for delivery of therapeutic capable agents with variable release profile |
US7276362B2 (en) | 2004-01-30 | 2007-10-02 | Roche Diagnostics Operations, Inc. | Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides |
CA2553881A1 (en) * | 2004-04-26 | 2005-11-10 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Process for preparation of mycophenolic acid and ester derivatives thereof |
BRPI0702901A2 (pt) * | 2006-06-29 | 2011-03-15 | Ivax Pharmaceuticals Sro | processos para regulação da produção de ácido metabólico e variantes do penicillium sp |
BRPI0803097A2 (pt) * | 2007-04-11 | 2011-11-08 | Teva Gyogyszergyar ... | método para redução do nìvel de impurezas na fermentação do ácido micofenólico |
CN113396226A (zh) * | 2019-01-31 | 2021-09-14 | 豪夫迈·罗氏有限公司 | 氨检测测定中nadph或nadh的稳定化 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
US5665583A (en) * | 1988-08-12 | 1997-09-09 | Arch Dev Corp | Methods and materials relating to IMPDH and GMP production |
US5283257A (en) * | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
WO1994012184A1 (en) * | 1992-11-24 | 1994-06-09 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
US5380879A (en) * | 1994-02-18 | 1995-01-10 | Syntex (U.S.A.) Inc. | Derivatives of mycophenolic acid |
US5444072A (en) * | 1994-02-18 | 1995-08-22 | Syntex (U.S.A.) Inc. | 6-substituted mycophenolic acid and derivatives |
US6225073B1 (en) * | 1994-07-07 | 2001-05-01 | Dade Behring Marburg Gmbh | Immunoassay for mycophenolic acid |
US5807876A (en) * | 1996-04-23 | 1998-09-15 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme |
PL192628B1 (pl) * | 1996-04-23 | 2006-11-30 | Vertex Pharma | Pochodne mocznika, kompozycje farmaceutyczne i zastosowanie związku i kompozycji |
US6153398A (en) * | 1997-12-24 | 2000-11-28 | The University Of Chicago | Method to identify specific inhibitors of IMP dehydrogenase |
-
1999
- 1999-06-09 US US09/328,741 patent/US6107052A/en not_active Expired - Lifetime
-
2000
- 2000-05-11 AT AT00935908T patent/ATE333510T1/de active
- 2000-05-11 CA CA002339821A patent/CA2339821C/en not_active Expired - Lifetime
- 2000-05-11 ES ES00935908T patent/ES2267541T3/es not_active Expired - Lifetime
- 2000-05-11 EP EP00935908A patent/EP1112373B1/de not_active Expired - Lifetime
- 2000-05-11 WO PCT/US2000/012872 patent/WO2000075363A2/en active IP Right Grant
- 2000-05-11 JP JP2001501643A patent/JP3854864B2/ja not_active Expired - Lifetime
- 2000-05-11 DE DE60029413T patent/DE60029413T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2003523730A (ja) | 2003-08-12 |
ES2267541T3 (es) | 2007-03-16 |
WO2000075363A3 (en) | 2001-04-12 |
CA2339821A1 (en) | 2000-12-14 |
EP1112373B1 (de) | 2006-07-19 |
EP1112373A2 (de) | 2001-07-04 |
CA2339821C (en) | 2009-01-27 |
WO2000075363A2 (en) | 2000-12-14 |
DE60029413T2 (de) | 2007-02-22 |
JP3854864B2 (ja) | 2006-12-06 |
US6107052A (en) | 2000-08-22 |
ATE333510T1 (de) | 2006-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |