DE60022025D1 - Anlage zum brechen von zellen - Google Patents

Anlage zum brechen von zellen

Info

Publication number
DE60022025D1
DE60022025D1 DE60022025T DE60022025T DE60022025D1 DE 60022025 D1 DE60022025 D1 DE 60022025D1 DE 60022025 T DE60022025 T DE 60022025T DE 60022025 T DE60022025 T DE 60022025T DE 60022025 D1 DE60022025 D1 DE 60022025D1
Authority
DE
Germany
Prior art keywords
sample
cartridge
cells
appendix
analyte
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60022025T
Other languages
English (en)
Other versions
DE60022025T2 (de
Inventor
T Taylor
Phillip Belgrader
Frazad Pourahmadi
A Mcmillan
Ronald Chang
H Sakai
Jesus Ching
E Petersen
Allen Northrup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cepheid
Original Assignee
Cepheid
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cepheid filed Critical Cepheid
Publication of DE60022025D1 publication Critical patent/DE60022025D1/de
Application granted granted Critical
Publication of DE60022025T2 publication Critical patent/DE60022025T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/066—Lysis of microorganisms by physical methods
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809—Multifield plates or multicontainer arrays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/877—With flow control means for branched passages
    • Y10T137/87708—With common valve operator
    • Y10T137/87716—For valve having a flexible diaphragm valving member
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87917—Flow path with serial valves and/or closures
    • Y10T137/88046—Biased valve with external operator
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
DE2000622025 1999-05-28 2000-05-30 Anlage zum brechen von zellen Expired - Lifetime DE60022025T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13670399P 1999-05-28 1999-05-28
US136703P 1999-05-28
PCT/US2000/014740 WO2000073413A2 (en) 1999-05-28 2000-05-30 Apparatus and method for cell disruption

Publications (2)

Publication Number Publication Date
DE60022025D1 true DE60022025D1 (de) 2005-09-22
DE60022025T2 DE60022025T2 (de) 2006-06-29

Family

ID=22473993

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2000622025 Expired - Lifetime DE60022025T2 (de) 1999-05-28 2000-05-30 Anlage zum brechen von zellen
DE2000614676 Expired - Lifetime DE60014676T2 (de) 1999-05-28 2000-05-30 Vorrichtung und verfahren zur analyse flüssiger proben

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2000614676 Expired - Lifetime DE60014676T2 (de) 1999-05-28 2000-05-30 Vorrichtung und verfahren zur analyse flüssiger proben

Country Status (8)

Country Link
US (7) US6391541B1 (de)
EP (2) EP1208189B1 (de)
JP (2) JP4078073B2 (de)
AT (2) ATE278771T1 (de)
AU (2) AU780073B2 (de)
CA (2) CA2374423C (de)
DE (2) DE60022025T2 (de)
WO (2) WO2000073413A2 (de)

Families Citing this family (514)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US8293064B2 (en) * 1998-03-02 2012-10-23 Cepheid Method for fabricating a reaction vessel
ES2544455T3 (es) * 1997-02-28 2015-08-31 Cepheid Montaje para reacción química con intercambio de calor, ópticamente interrogada
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6958392B2 (en) * 1998-10-09 2005-10-25 Whatman, Inc. Methods for the isolation of nucleic acids and for quantitative DNA extraction and detection for leukocyte evaluation in blood products
US7914994B2 (en) * 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US6818185B1 (en) * 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
JP4078073B2 (ja) 1999-05-28 2008-04-23 シーフィード 流体試料分析装置および方法
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US6706519B1 (en) * 1999-06-22 2004-03-16 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
US6878540B2 (en) * 1999-06-25 2005-04-12 Cepheid Device for lysing cells, spores, or microorganisms
EP1080785A1 (de) * 1999-09-04 2001-03-07 F. Hoffmann-La Roche Ag Thermozyklisches System für Fluide in Patronen
US8518328B2 (en) * 2005-12-27 2013-08-27 Honeywell International Inc. Fluid sensing and control in a fluidic analyzer
JP3638503B2 (ja) * 2000-06-12 2005-04-13 アークレイ株式会社 カートリッジ式容器を用いる測定装置および測定方法並びに記録媒体
ATE428105T1 (de) * 2000-07-21 2009-04-15 Senzime Point Of Care Ab Mikro-calorimetervorrichtung
FR2812303B1 (fr) * 2000-07-27 2002-12-06 Biomerieux Sa Procede de lyse cellulaire de procaryotes ou d'eucaryotes ou de lyse cellulaire simultanee de procaryotes et d'eucaryotes
US8048386B2 (en) 2002-02-25 2011-11-01 Cepheid Fluid processing and control
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
AUPR298901A0 (en) 2001-02-07 2001-03-08 McComb Foundation, Inc., The Cell suspension preparation technique and device
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
EP1390466A4 (de) * 2001-04-26 2010-07-28 Pressure Biosciences Inc Mehrkammervorrichtung und ihre verwendung zur bearbeitung biologischer proben
GB0110476D0 (en) * 2001-04-30 2001-06-20 Secr Defence Reagent delivery system
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8337419B2 (en) * 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
EP1404235A4 (de) 2001-06-12 2008-08-20 Pelikan Technologies Inc Verfahren und gerät für eine auf einer blutentnahmekartusche integrierte lanzettenvorrichtung
EP1404233B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
JP4149911B2 (ja) 2001-06-12 2008-09-17 ペリカン テクノロジーズ インコーポレイテッド 電気式ランセットアクチュエータ
JP4358618B2 (ja) * 2001-07-19 2009-11-04 ジェネオーム サイエンシズ カナダ インコーポレイティド 核酸の放出及びそれらを検出するための細胞を迅速に溶解せしめるための万能な方法及び組成物
AU2002356053A1 (en) * 2001-08-20 2003-03-03 Whatman, Inc. Dna purification and recovery from high particulate and solids samples
US6739531B2 (en) * 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses
DE10153925B4 (de) * 2001-11-02 2005-08-11 Unlimited Pharmaceutical Deutschland Gmbh Testgerät zum Nachweis von pharmakologisch wirksamen Verbindungen aus Speichel
WO2003065355A2 (en) * 2002-01-31 2003-08-07 Burstein Technologies, Inc. Bio-safety features for optical analysis disc and disc system including same
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) * 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) * 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) * 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
EP2500076B1 (de) 2002-04-26 2017-11-01 Abbott Laboratories Struktur und Verfahren zur Handhabung magnetischer Partikel in biologischen Tests
US7220573B2 (en) * 2002-06-21 2007-05-22 Agilent Technologies, Inc. Array assay devices and methods of using the same
DE10228917A1 (de) * 2002-06-24 2004-01-22 Epigenomics Ag Vorrichtung zur Handhabung von Flüssigkeiten in einer Mehrzahl von Kanälen
MXPA05000816A (es) 2002-07-19 2005-04-28 Baxter Int Sistemas y metodos para realizar dialisis peritoneal.
US7745203B2 (en) * 2002-07-31 2010-06-29 Kabushiki Kaisha Toshiba Base sequence detection apparatus and base sequence automatic analyzing apparatus
US20040038385A1 (en) * 2002-08-26 2004-02-26 Langlois Richard G. System for autonomous monitoring of bioagents
US20120296233A9 (en) * 2002-09-05 2012-11-22 Freeman Dominique M Methods and apparatus for an analyte detecting device
WO2004084263A2 (en) * 2002-09-07 2004-09-30 Arizona Board Of Regents Integrated apparatus and methods for treating liquids
AU2003277069A1 (en) * 2002-09-30 2004-04-23 Ciphergen Biosystems, Inc. Apparatus and method for expression and capture of biomolecules and complexes on adsorbent surfaces
EP1551989A1 (de) 2002-10-17 2005-07-13 Conestoga-Rovers & Associated Limited Schnelles detektionssystem für coliforme bakterien
US20040086872A1 (en) * 2002-10-31 2004-05-06 Childers Winthrop D. Microfluidic system for analysis of nucleic acids
US7932098B2 (en) * 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
GB2395196B (en) * 2002-11-14 2006-12-27 Univ Cardiff Microfluidic device and methods for construction and application
AU2003302455A1 (en) * 2002-11-28 2004-06-18 Arkray Inc. Device for pretreating specimen
GB0227765D0 (en) * 2002-11-28 2003-01-08 Secr Defence Apparatus for processing a fluid sample
US6929945B2 (en) * 2002-12-09 2005-08-16 Advanced Fluidix Laboratories Llc Male fertility assay method and device
EP1583950B1 (de) * 2002-12-26 2017-04-05 Meso Scale Technologies, LLC. Testkassetten und verfahren zu ihrer verwendung
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004083806A2 (en) 2003-01-22 2004-09-30 University Of South Florida Autonomous genosensor apparatus and methods for use
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
ES2347248T3 (es) * 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
US7850621B2 (en) * 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) * 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1635700B1 (de) * 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Gerät für eine point of care vorrichtung
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
WO2004113871A2 (en) * 2003-06-19 2004-12-29 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7601545B2 (en) * 2003-06-20 2009-10-13 Groton Biosystems, Llc Automated macromolecule sample preparation system
US7341652B2 (en) * 2003-06-20 2008-03-11 Groton Biosytems, Llc Stationary capillary electrophoresis system
US20040259076A1 (en) * 2003-06-23 2004-12-23 Accella Scientific, Inc. Nano and micro-technology virus detection method and device
JP2007500351A (ja) * 2003-07-25 2007-01-11 長岡実業株式会社 バイオディスクを有するサンプル調製用流体回路及びそれに関連した方法
WO2005011867A2 (en) 2003-07-31 2005-02-10 Handylab, Inc. Processing particle-containing samples
US20050054114A1 (en) * 2003-09-09 2005-03-10 Bayer Corporation Fluidics circuit of hematology analyzer with heated reaction chamber
WO2005028635A2 (en) * 2003-09-19 2005-03-31 Microfluidic Systems Inc. Microfluidic differential extraction cartridge
JP4522800B2 (ja) * 2003-09-19 2010-08-11 富士フイルム株式会社 抽出装置
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7032605B1 (en) 2003-10-15 2006-04-25 Douglas B. Dority Dual piston rotary valve
DK1685385T3 (da) * 2003-10-30 2009-07-20 Bayer Healthcare Llc Rammer til optisk analyse og fremgangsmåder til fremstilling deraf
CA2542897A1 (en) 2003-10-30 2005-05-12 Bayer Healthcare Llc Optical cuvette with platform-and-well construction
WO2005055804A2 (en) 2003-12-02 2005-06-23 Musc Foundation For Research Development Methods and compositions for diagnosing epithelial cell cancer
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US20080312555A1 (en) * 2004-02-06 2008-12-18 Dirk Boecker Devices and methods for glucose measurement using rechargeable battery energy sources
US7981616B2 (en) 2004-02-27 2011-07-19 Musc Foundation For Research Development Enhanced detection of RNA using a panel of truncated gene-specific primers for reverse transcription
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
DE102004017178A1 (de) * 2004-04-07 2005-11-03 Siemens Ag Vorrichtung und Verfahren zum Betätigen eines Ventils in einem mikromechanischen Gerät
ES2643836T3 (es) 2004-04-07 2017-11-24 Abbott Laboratories Cámara desechable para analizar fluidos biológicos
US20050244837A1 (en) * 2004-04-28 2005-11-03 Cepheid Method and device for sample preparation control
DE102004021780B4 (de) * 2004-04-30 2008-10-02 Siemens Ag Verfahren und Anordnung zur DNA-Isolierung mit Trockenreagenzien
DE102004021822B3 (de) 2004-04-30 2005-11-17 Siemens Ag Verfahren und Anordnung zur DNA-Amplifikation mittels PCR unter Einsatz von Trockenreagenzien
ES2553097T3 (es) 2004-05-03 2015-12-04 Handylab, Inc. Procesamiento de muestras que contienen polinucleótidos
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
DE102005052713A1 (de) 2005-11-04 2007-05-16 Clondiag Chip Tech Gmbh Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen
EP1751546A2 (de) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Bedruckbares wassergel für biosensoren
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2005120365A1 (en) * 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
EP1611954A1 (de) * 2004-07-03 2006-01-04 Roche Diagnostics GmbH Verbindungsstück zwischen Flüssigkeitsbehältern
EP2272987A3 (de) 2004-07-09 2012-04-11 University of Pittsburgh of the Commonwealth System of Higher Education Identifizierung von Markern für Speiseröhren-, Dickdarm-, Kopf- und Nackenkrebs und Melanom
US7611840B2 (en) * 2004-08-03 2009-11-03 Agency For Science, Technology And Research Method and device for the treatment of biological samples
WO2006029387A1 (en) * 2004-09-09 2006-03-16 Microfluidic Systems Inc. A handheld and portable microfluidic device to automatically prepare nucleic acids for analysis
WO2006039293A2 (en) * 2004-09-29 2006-04-13 University Of Virginia Patent Foundation Localized control of thermal properties on microdevices and applications thereof
US8056881B2 (en) 2004-10-13 2011-11-15 University Of Virginia Patent Foundation Electrostatic actuation for management of flow in micro-total analysis systems (μ-TAS) and related method thereof
EP1650297B1 (de) 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Verfahren und Apparatur zur schnellen Zerstörung von Zellen und Viren durch die Verwendung von mikro magnet Kügelchen und Laser
US20080305538A1 (en) * 2004-10-19 2008-12-11 Medical Innovations International, Inc. Rapid and Sensitive Detection of Bacteria in Blood Products, Urine, and Other Fluids
KR100601972B1 (ko) * 2004-11-03 2006-07-18 삼성전자주식회사 레이저와 비드를 이용한 상 분리에 의한 핵산의 정제 장치및 방법
KR100601974B1 (ko) * 2004-11-25 2006-07-18 삼성전자주식회사 비드의 상이한 레이저 흡수에 의한 핵산의 정제 장치 및방법
US7785868B2 (en) * 2004-12-02 2010-08-31 Microfluidic Systems, Inc. Apparatus to automatically lyse a sample
CN100388967C (zh) * 2004-12-02 2008-05-21 鸿富锦精密工业（深圳）有限公司 颗粒分散方法及其设备
US20080277387A1 (en) * 2004-12-22 2008-11-13 Landers James P Use of Microwaves For Thermal and Non-Thermal Applications in Micro and Nanoscale Devices
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
CN101031802B (zh) * 2005-01-07 2012-11-07 积水化学工业株式会社 使用盒的检测装置
KR100601983B1 (ko) * 2005-01-20 2006-07-18 삼성전자주식회사 시료 내 핵산 증폭 저해 물질의 제거 방법
WO2006081479A2 (en) * 2005-01-27 2006-08-03 Applera Corporation Sample preparation devices and methods
US20060203236A1 (en) * 2005-03-08 2006-09-14 Zhenghua Ji Sample cell
JP4656992B2 (ja) * 2005-04-14 2011-03-23 積水化学工業株式会社 マイクロフィルターユニット
US20060257907A1 (en) * 2005-04-19 2006-11-16 The Regents Of The University Of California Packed bed for nucleic acid capture and amplification
US20070014695A1 (en) * 2005-04-26 2007-01-18 Applera Corporation Systems and Methods for Multiple Analyte Detection
KR101762424B1 (ko) 2005-05-09 2017-07-28 테라노스, 인코포레이티드 현장진료 유체 시스템 및 그 용도
EP3714979A1 (de) * 2005-05-09 2020-09-30 BioFire Diagnostics, LLC In sich geschlossene biologische analyse
US10816563B2 (en) 2005-05-25 2020-10-27 Boehringer Ingelheim Vetmedica Gmbh System for operating a system for the integrated and automated analysis of DNA or protein
ES2871885T3 (es) 2005-05-25 2021-11-02 Boehringer Ingelheim Vetmedica Gmbh Sistema para el análisis integrado y automatizado de ADN o proteínas y procedimientos operativos de dicho sistema
AU2006309284B2 (en) 2005-05-31 2012-08-02 Board Of Regents, The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
WO2006132666A1 (en) 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
WO2007002480A2 (en) * 2005-06-24 2007-01-04 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
WO2007006049A2 (en) * 2005-07-06 2007-01-11 The Regents Of The University Of California Apparatuses, systems, and methods for isolating and separating biological materials
ITBO20050481A1 (it) 2005-07-19 2007-01-20 Silicon Biosystems S R L Metodo ed apparato per la manipolazione e/o l'individuazione di particelle
US8343755B2 (en) * 2005-08-01 2013-01-01 University Of Virginia Patent Foundation Microdevices for chemical sensing and chemical actuation
TW200712487A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus and method for detecting an analyte
TW200712489A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus assembly and method for detecting an analyte
TW200714898A (en) * 2005-08-02 2007-04-16 3M Innovative Properties Co Apparatus and method for detecting an analyte
TW200712495A (en) * 2005-08-02 2007-04-01 3M Innovative Properties Co Apparatus and method for detecting an analyte
US8220493B2 (en) * 2005-08-23 2012-07-17 University Of Virginia Patent Foundation Passive components for micro-fluidic flow profile shaping and related method thereof
US8480053B2 (en) 2005-09-02 2013-07-09 California Institute Of Technology Method and apparatus for the mechanical actuation of valves in fluidic devices
KR100700093B1 (ko) * 2005-09-23 2007-03-28 삼성전자주식회사 레이저 및 자성 비드를 이용한 세포 또는 바이러스 파괴장치
ES2379921T3 (es) 2005-09-29 2012-05-07 Siemens Medical Solutions Usa, Inc. Chip microfluídico que puede sintetizar moléculas marcadas radiactivamente en una escala adecuada para la obtención de imágenes en seres humanos con tomografía por emisión de positrones
US20110033922A1 (en) * 2005-10-04 2011-02-10 Landers James P Microchip-based acoustic trapping or capture of cells for forensic analysis and related method thereof
EP1945815A4 (de) * 2005-10-11 2009-02-18 Handylab Inc Polynukleotidprobenvorbereitungsvorrichtung
US8916375B2 (en) * 2005-10-12 2014-12-23 University Of Virginia Patent Foundation Integrated microfluidic analysis systems
US7731901B2 (en) * 2005-10-19 2010-06-08 Abbott Laboratories Apparatus and method for performing counts within a biologic fluid sample
ITBO20050646A1 (it) 2005-10-26 2007-04-27 Silicon Biosystem S R L Metodo ed apparato per la caratterizzazione ed il conteggio di particelle
WO2007055165A1 (ja) * 2005-11-11 2007-05-18 Konica Minolta Medical & Graphic, Inc. 核酸の分離方法、核酸検査用マイクロリアクタ、核酸検査システム
CN101365781A (zh) * 2005-11-21 2009-02-11 阿普尔拉公司 用于核酸处理的便携式制备、分析和检测设备
US7485153B2 (en) * 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
US8182767B2 (en) * 2005-12-27 2012-05-22 Honeywell International Inc. Needle-septum interface for a fluidic analyzer
WO2007092472A1 (en) * 2006-02-03 2007-08-16 Arkadij Elizarov A microfluidic method and structure with an elastomeric gas-permeable gasket
US7862000B2 (en) 2006-02-03 2011-01-04 California Institute Of Technology Microfluidic method and structure with an elastomeric gas-permeable gasket
EP1979079A4 (de) 2006-02-03 2012-11-28 Integenx Inc Mikrofluidische vorrichtungen
DE202006020469U1 (de) 2006-03-06 2008-10-16 Directif Gmbh Vorrichtung zum Nachweis biochemischer Zielmoleküle
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2007112114A2 (en) 2006-03-24 2007-10-04 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
EP1997888A4 (de) * 2006-03-24 2010-07-28 Toshiba Kk Nukleinsäuredetektionskassette und nukleinsäuredetektionsvorrichtung
US7507583B2 (en) * 2006-03-27 2009-03-24 Savannah River Nuclear Solutions, Llc Analysis of large soil samples for actinides
ITTO20060226A1 (it) 2006-03-27 2007-09-28 Silicon Biosystem S P A Metodo ed apparato per il processamento e o l'analisi e o la selezione di particelle, in particolare particelle biologiche
JP2009535636A (ja) * 2006-05-01 2009-10-01 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 流体サンプルを処理、制御及び／又は検出するための低減された死容積を有する流体サンプル輸送装置
US8900828B2 (en) * 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
US20100216657A1 (en) * 2006-05-16 2010-08-26 Arcxis Biotechnologies, Inc. Pcr-free sample preparation and detection systems for high speed biologic analysis and identification
US8119352B2 (en) 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
US7549349B2 (en) * 2006-06-22 2009-06-23 Evogen, Inc. Sample cartridge for air-sampling device
WO2008002563A2 (en) * 2006-06-26 2008-01-03 Applera Corporation Heated cover methods and technology
US7629124B2 (en) 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
EP3450019A1 (de) * 2006-07-28 2019-03-06 Diagnostics for the Real World, Ltd Vorrichtung und system zur verarbeitung einer probe
US7705739B2 (en) * 2006-08-24 2010-04-27 Microfluidic Systems, Inc. Integrated airborne substance collection and detection system
US7633606B2 (en) * 2006-08-24 2009-12-15 Microfluidic Systems, Inc. Integrated airborne substance collection and detection system
US7858366B2 (en) * 2006-08-24 2010-12-28 Microfluidic Systems, Inc Integrated airborne substance collection and detection system
US20080069732A1 (en) * 2006-09-20 2008-03-20 Robert Yi Diagnostic test system
US20070080613A1 (en) * 2006-09-20 2007-04-12 Sterlite Optical Technologies Ltd Storage and transportation device for storing and transporting optical fiber preform and precursors thereof
US20080131327A1 (en) * 2006-09-28 2008-06-05 California Institute Of Technology System and method for interfacing with a microfluidic chip
US20100167329A1 (en) * 2006-10-06 2010-07-01 Respiratorius Ab Device for drug screening
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
EP2091647A2 (de) 2006-11-14 2009-08-26 Handylab, Inc. Mikrofluidisches system für parallele amplifikation und erkennung von polynukleotiden
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
US20080124777A1 (en) * 2006-11-29 2008-05-29 Canon U.S. Life Sciences, Inc. Method for releasing genetic material from solid phase
US20080121591A1 (en) * 2006-11-29 2008-05-29 Canon U.S. Life Sciences, Inc. Device for nucleic acid preparation
US20080131954A1 (en) * 2006-11-30 2008-06-05 Canon U.S. Life Sciences, Inc. Method of Separating Target DNA from Mixed DNA
US20100028896A1 (en) 2006-12-19 2010-02-04 Konica Minolta Medical & Graphic, Inc. Rotary extraction container and method of identifying cell species, method of detecting gene, and automatic nucleic acid extractor using the same
US8338166B2 (en) * 2007-01-04 2012-12-25 Lawrence Livermore National Security, Llc Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
WO2008091694A2 (en) 2007-01-23 2008-07-31 Siemens Medical Solutions Usa, Inc. Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography
US7830560B2 (en) 2007-01-31 2010-11-09 Hewlett-Packard Development Company, L.P. System and method for adaptive digital ramp current control
WO2008109878A2 (en) * 2007-03-07 2008-09-12 California Institute Of Technology Testing device
US8153064B2 (en) * 2007-03-22 2012-04-10 Doebler Ii Robert W Systems and devices for isothermal biochemical reactions and/or analysis
EP2149610B1 (de) 2007-03-26 2018-05-16 Fundacion Gaiker Vorrichtung zum nachweis genetischen materials mittels polymerasekettenreaktion
JP5557733B2 (ja) 2007-04-04 2014-07-23 ネットバイオ・インコーポレーテッド プラスチック製マイクロ流体分離および検出プラットフォーム
US8071035B2 (en) 2007-04-12 2011-12-06 Siemens Medical Solutions Usa, Inc. Microfluidic radiosynthesis system for positron emission tomography biomarkers
FR2917095B1 (fr) 2007-06-07 2009-07-17 Biomerieux Sa Dispositif de lyse de microorganismes presents dans un echantillon environnemental ou clinique et d'extraction des acides nucleiques desdits microorganismes aux fins d'analyse.
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8324372B2 (en) 2007-07-13 2012-12-04 Handylab, Inc. Polynucleotide capture materials, and methods of using same
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
CA3006347A1 (en) * 2007-07-23 2009-01-29 Clondiag Gmbh Methods and devices for determining values indicative of the presence and/or amount of nucleic acids
US20090030342A1 (en) * 2007-07-27 2009-01-29 3M Innovative Properties Company Apparatus and method for releasing a sample of material
GB0715170D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Reaction vessel
GB0715171D0 (en) * 2007-08-03 2007-09-12 Enigma Diagnostics Ltd Sample processor
EP2178640A1 (de) * 2007-08-03 2010-04-28 Enigma Diagnostics Limited Reaktionsgefäss
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
WO2009026394A1 (en) * 2007-08-20 2009-02-26 Pelikan Technologies, Inc. Body fluid sampling systems
US7892331B2 (en) * 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
US8444587B2 (en) 2007-10-01 2013-05-21 Baxter International Inc. Fluid and air handling in blood and dialysis circuits
US7871462B2 (en) * 2007-10-01 2011-01-18 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
US7892332B2 (en) * 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air traps with internal structures to enhance air removal
WO2009046227A1 (en) 2007-10-02 2009-04-09 Theranos, Inc. Modular point-of-care devices and uses thereof
US20100236637A1 (en) * 2007-10-05 2010-09-23 Hendrix Jr James Edward Surface Ventilator For A Compliant-Surface Flow-Control Device
US8123947B2 (en) * 2007-10-22 2012-02-28 Baxter International Inc. Priming and air removal systems and methods for dialysis
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
ITTO20070771A1 (it) 2007-10-29 2009-04-30 Silicon Biosystems Spa Metodo e apparato per la identificazione e manipolazione di particelle
US8381169B2 (en) * 2007-10-30 2013-02-19 International Business Machines Corporation Extending unified process and method content to include dynamic and collaborative content
US20090111193A1 (en) 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device
US10125388B2 (en) 2007-10-31 2018-11-13 Akonni Biosystems, Inc. Integrated sample processing system
US7759112B2 (en) * 2007-10-31 2010-07-20 Akonni Biosystems, Inc. Apparatus, system, and method for purifying nucleic acids
US9428746B2 (en) 2007-10-31 2016-08-30 Akonni Biosystems, Inc. Method and kit for purifying nucleic acids
US20090137024A1 (en) * 2007-11-28 2009-05-28 Canon U.S. Life Sciences, Inc. Method of Separating Target DNA from Mixed DNA
EP2232245A1 (de) * 2007-12-06 2010-09-29 Agency for Science, Technology And Research Integrierte vorrichtung zur durchführung und überwachung chemischer reaktionen
EP2232259B1 (de) * 2008-01-09 2016-10-12 Keck Graduate Institute System, vorrichtung und verfahren zur materialvorbereitung und/oder -handhabung
GB0800798D0 (en) * 2008-01-17 2008-02-27 Secr Defence An acoustic device
EP2255010B1 (de) * 2008-02-20 2018-05-30 Streck Inc. Thermocycler und probengefäss zur schnellen amplifikation von dna
US8096786B2 (en) 2008-02-27 2012-01-17 University Of Massachusetts Three dimensional micro-fluidic pumps and valves
US8857279B2 (en) * 2008-03-03 2014-10-14 William P. Hanson Analyte screening and detection systems and methods
CN102047124B (zh) * 2008-03-31 2013-07-17 新加坡科技研究局 利用互连的多腔室装置的流体处理与传输
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US8961902B2 (en) 2008-04-23 2015-02-24 Bioscale, Inc. Method and apparatus for analyte processing
DE102008021000A1 (de) 2008-04-25 2009-10-29 Qiagen Gmbh Verfahren und Vorrichtung zum Aufschluss von biologischem Material
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US8133451B2 (en) * 2008-08-28 2012-03-13 Microfluidic Systems, Inc. Sample preparation apparatus
JP2010099061A (ja) * 2008-09-26 2010-05-06 Sekisui Chem Co Ltd 検出用カートリッジ及び被検出物質の検出方法
US20100093098A1 (en) * 2008-10-14 2010-04-15 Siemens Medical Solutions Nonflow-through appratus and mehod using enhanced flow mechanisms
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
FR2938062B1 (fr) * 2008-11-05 2014-02-28 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
FR2938063B1 (fr) 2008-11-05 2014-09-19 Commissariat Energie Atomique Dispositif de preparation et/ou de traitement d'un echantillon biologique
FR2939445B1 (fr) 2008-12-10 2013-05-03 Biomerieux Sa Systeme automatise de lyse de microorganismes presents dans un echantillon, d'extraction et de purification des acides nucleiques desdits microorganismes aux fins d'analyse.
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
KR101786506B1 (ko) * 2009-02-03 2017-10-18 네트바이오, 인코포레이티드 핵산 정제
AU2015215950B2 (en) * 2009-02-03 2017-06-29 Ande Corporation Nucleic Acid Purification
DK2408562T3 (en) * 2009-03-17 2018-06-06 Menarini Silicon Biosystems Spa Microfluidic device for isolating cells
ITBO20090154A1 (it) * 2009-03-17 2010-09-18 Silicon Biosystems Spa Sistema microfluidico
WO2010120786A1 (en) 2009-04-13 2010-10-21 Micronics, Inc. Microfluidic clinical analyzer
EP3357568A1 (de) 2009-04-14 2018-08-08 Biocartis NV Hifu-induzierte kavitation mit verringerter leistungsschwelle
ES2822105T3 (es) 2009-04-15 2021-04-29 Biocartis Nv Sistema de detección óptica para monitorizar la reacción rtPCR
RU2522350C2 (ru) 2009-04-15 2014-07-10 Биокартис Са Защита биоаналитических камер для пробы
ES2540118T3 (es) 2009-05-06 2015-07-08 Biocartis Nv Dispositivo para cortar un portamuestras
US20100291536A1 (en) * 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
US8282789B2 (en) * 2009-05-18 2012-10-09 Bing-Nan Lee Microwave apparatus and method of extracting essential oils, essence, and pigments with gas flow
US8282788B2 (en) * 2009-05-18 2012-10-09 Bing-Nan Lee Extraction apparatus and method of extracting essential oils, essence, and pigments from odorous raw material by microwave heating under sub-critical conditions
US20110130560A1 (en) * 2009-05-29 2011-06-02 Bio-Rad Laboratories, Inc. Sonication cartridge for nucleic acid extraction
RU2559541C2 (ru) 2009-06-05 2015-08-10 Интедженкс Инк. Универсальная система подготовки образцов и применение в интегрированной системе анализа
WO2010147654A2 (en) 2009-06-15 2010-12-23 Netbio Inc. Improved methods for forensic dna quantitation
EP2446047B1 (de) * 2009-06-26 2017-10-18 Claremont Biosolutions LLC Erfassung und eluierung von bioanalyten mithilfe von kügelchen zur probenzerteilung
EP2453219A4 (de) * 2009-07-09 2016-06-15 Toppan Printing Co Ltd Nukleinsäureextraktionskit, nukleinsäureextraktionsverfahren und nukleinsäureextraktionsvorrichtung
NZ599873A (en) 2009-10-19 2014-09-26 Theranos Inc Integrated health data capture and analysis system
US20110091873A1 (en) * 2009-10-21 2011-04-21 Microfluidic Systems, Inc. Integrated sample preparation and amplification for nucleic acid detection from biological samples
US9034280B2 (en) * 2009-12-16 2015-05-19 General Electric Corporation High-throughput methods and systems for processing biological materials
WO2011075667A2 (en) 2009-12-18 2011-06-23 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
JP2013515956A (ja) * 2009-12-23 2013-05-09 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 検体測定装置及び方法
CA2786569C (en) 2010-01-29 2019-04-09 Micronics, Inc. Sample-to-answer microfluidic cartridge
KR101882940B1 (ko) * 2010-02-23 2018-07-30 루미넥스 코포레이션 일체화된 샘플 제조, 반응 및 검출을 위한 장치 및 방법
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
FR2959312B1 (fr) 2010-04-23 2023-01-20 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
WO2011151804A1 (en) 2010-06-03 2011-12-08 Spinomix S.A. A fluidic interfacing system and assembly
US20180071733A1 (en) * 2010-08-02 2018-03-15 Dxna Llc Pressurizable cartridge for polymerase chain reactions
CN103210079B (zh) * 2010-08-02 2015-07-22 B·L·韦特 用于聚合酶链式反应的可增压筒
ITBO20100502A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
ITBO20100504A1 (it) * 2010-08-04 2012-02-05 Silicon Biosystems Spa Sistema microfluidico
EP2606154B1 (de) 2010-08-20 2019-09-25 Integenx Inc. Integriertes analysesystem
JP5837742B2 (ja) * 2010-08-27 2015-12-24 学校法人東京女子医科大学 細胞単離装置
JP5909654B2 (ja) * 2010-09-24 2016-04-27 パナソニックＩｐマネジメント株式会社 フィルターデバイス
KR101254675B1 (ko) * 2010-10-25 2013-04-15 주식회사 싸이토젠 세포 채집 장치
KR101420094B1 (ko) 2010-10-27 2014-07-17 (주)바이오니아 다양한 생체시료분석을 위한 전자동실시간정량증폭장비, 다양한 생체시료분석을 위한 자동정제 및 반응준비 장치, 전자동 핵산정제 및 실시간 정량 유전자증폭 방법, 전자동 핵산정제방법, 실시간정량ｐｃｒ을 이용한 병원균의 전자동 생균수검사방법, 정량면역ｐｃｒ을 이용한 전자동 항원농도획득방법 및 타겟항원에 라벨링된 부착용 타겟핵산의 정제방법
US8986986B2 (en) 2010-10-29 2015-03-24 Samsung Electronics Co., Ltd. Cell lysis device and methods of lysing cells or viruses
KR101776215B1 (ko) * 2010-10-29 2017-09-08 삼성전자 주식회사 세포 파쇄용 마이크로 디바이스 및 이를 이용한 세포 파쇄 방법
US8663974B2 (en) 2010-12-23 2014-03-04 Claremont Biosolutions Llc Compositions and methods for capture and elution of biological materials via particulates
US8382711B2 (en) 2010-12-29 2013-02-26 Baxter International Inc. Intravenous pumping air management systems and methods
EP2658653B1 (de) 2010-12-30 2015-03-04 Abbott Point Of Care, Inc. Kassette zur analyse biologischer proben mit probebehandlungsteil und analysekammerteil
WO2012096480A2 (en) 2011-01-10 2012-07-19 Lg Electronics Inc. Diagnostic cartridge and control method for diagnostic cartridge
CA3097861A1 (en) 2011-01-21 2012-07-26 Labrador Diagnostics Llc Systems and methods for sample use maximization
WO2012142516A1 (en) 2011-04-15 2012-10-18 Becton, Dickinson And Company Scanning real-time microfluidic thermo-cycler and methods for synchronized thermocycling and scanning optical detection
AU2012253271A1 (en) 2011-05-12 2014-01-09 Netbio, Inc. Methods and compositions for rapid multiplex amplification of STR loci
CA2835654A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
EP2532433A1 (de) * 2011-06-06 2012-12-12 Koninklijke Philips Electronics N.V. Vorrichtung zum Fragmentieren von Molekülen einer Probe durch Ultraschall
CA2842720C (en) 2011-07-25 2023-10-10 Qvella Corporation Methods and devices for electrical sample preparation
CN105817276B (zh) 2011-08-24 2018-02-06 艾博特健康公司 生物流体样品分析盒
US8808643B1 (en) 2011-09-08 2014-08-19 Lawrence Livermore National Security, Llc Fluidics platform and method for sample preparation and analysis
US9372135B1 (en) 2011-09-08 2016-06-21 Lawrence Livermore National Security, Llc Fluidics platform and method for sample preparation
US8988684B1 (en) 2011-09-08 2015-03-24 Lawrence Livermore National Security, Llc System and method for measuring fluorescence of a sample
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
ES2825905T3 (es) 2011-09-30 2021-05-17 Becton Dickinson Co Tira reactiva unificada
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
US20150136604A1 (en) * 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
KR101481054B1 (ko) 2011-11-15 2015-01-14 한국기계연구원 핵산 자동 분석 장치
ITBO20110766A1 (it) 2011-12-28 2013-06-29 Silicon Biosystems Spa Dispositivi, apparato, kit e metodo per il trattamento di un campione biologico
CN107881219B (zh) 2012-02-03 2021-09-10 贝克顿·迪金森公司 用于分子诊断测试分配和测试之间兼容性确定的外部文件
US11648561B2 (en) 2012-02-13 2023-05-16 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
US9604213B2 (en) 2012-02-13 2017-03-28 Neumodx Molecular, Inc. System and method for processing and detecting nucleic acids
CN104254595A (zh) 2012-02-13 2014-12-31 纽莫德克斯莫勒库拉尔公司 用于处理和检测核酸的微流体盒
US11485968B2 (en) 2012-02-13 2022-11-01 Neumodx Molecular, Inc. Microfluidic cartridge for processing and detecting nucleic acids
US9637775B2 (en) 2012-02-13 2017-05-02 Neumodx Molecular, Inc. System and method for processing biological samples
EP2825865B1 (de) * 2012-03-09 2020-07-22 Ubiquitome Limited Tragbare vorrichtung zur erkennung von molekülen
EP2825309B1 (de) 2012-03-16 2018-05-16 Stat-Diagnostica & Innovation, S.L. Messkartousche mit trasportmodul
DE102012205171B3 (de) 2012-03-29 2013-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Integriertes Einweg-Chipkartuschensystem für mobile Multiparameteranalysen chemischer und/oder biologischer Substanzen
ITTO20120320A1 (it) * 2012-04-12 2013-10-13 St Microelectronics Srl Dispositivo e metodo per la preparazione di campioni biologici, in particolare per l'estrazione del dna, e il caricamento in pozzetti per la successiva esecuzione della pcr
SG194247A1 (en) * 2012-04-16 2013-11-29 Biofactory Pte Ltd Method and apparatus for cell disruption
ES2619032T3 (es) 2012-04-20 2017-06-22 Cepheid Métodos de detección del cáncer de vejiga
BR112014026735B1 (pt) 2012-04-27 2021-11-23 Cepheid Aparelho de processamento de amostra biológica, e, método para operar um aparelho de processamento de amostra
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
EP2856120A4 (de) * 2012-06-05 2016-06-15 Dairy Quality Inc System und verfahren zur analyse biologischer flüssigkeiten
US9399986B2 (en) 2012-07-31 2016-07-26 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
US20150259671A1 (en) * 2012-07-31 2015-09-17 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
WO2014025398A1 (en) 2012-08-10 2014-02-13 Streck, Inc. Real-time optical system for polymerase chain reaction
NL2017959B1 (en) * 2016-12-08 2018-06-19 Illumina Inc Cartridge assembly
EP2900836B1 (de) 2012-09-28 2023-05-10 Cepheid Pcr mit zwei primern für ein mikrorns-multiplex-assay
JP1628115S (de) 2012-10-24 2019-04-01
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
DE102012219575A1 (de) * 2012-10-25 2014-04-30 Robert Bosch Gmbh Zum Lysieren einsetzbare Vorrichtungen, Verfahren und System
WO2014066376A1 (en) 2012-10-25 2014-05-01 Neumodx Molecular, Inc. Method and materials for isolation of nucleic acid materials
US10775397B2 (en) * 2012-11-16 2020-09-15 Universal Bio Research Co., Ltd. Linear movement type reaction treatment apparatus and method thereof
US9987576B2 (en) 2012-12-10 2018-06-05 University Of Virginia Patent Foundation Frequency-based filtering of mechanical actuation using fluidic device
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
EP2935559B1 (de) 2012-12-21 2020-09-16 PerkinElmer Health Sciences, Inc. Fluoreszenznachweissystem
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
US9587236B2 (en) * 2013-01-18 2017-03-07 Folim G. Halaka Continuous sonication for biotechnology applications and biofuel production
CA2898467A1 (en) 2013-01-18 2014-07-24 Biomeme Incorporated Analytic device
US20150361419A1 (en) * 2013-01-21 2015-12-17 Nanobiosys Inc. Microfluidic chip for extracting nucleic acids, device for extracting nucleic acids comprising same, and method for extracting nucleic acids using same
ES2715874T3 (es) 2013-03-06 2019-06-06 Cepheid Métodos de detección del cáncer de la vejiga
AU2013205148B2 (en) * 2013-03-14 2014-10-30 AVITA Medical Americas, LLC Systems and methods for tissue processing and preparation of cell suspension therefrom
WO2014150905A2 (en) 2013-03-15 2014-09-25 Genmark Diagnostics, Inc. Systems, methods, and apparatus for manipulating deformable fluid vessels
EP2972154A4 (de) * 2013-03-15 2016-11-16 Practichem Llc Mehrmessungsdurchflusszellenanordnung für die flüssigchromatografie
US9670479B2 (en) 2013-03-15 2017-06-06 F Cubed, LLC Sample preparation device and methods of use
US9194848B2 (en) 2013-03-15 2015-11-24 Practichem, Llc Multi-measurement flow cell assembly for liquid chromatography
CN104330549B (zh) * 2013-04-03 2017-01-25 艾博生物医药(杭州)有限公司 一种识别检测板的正反两面的装置及方法
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN105189750B (zh) 2013-05-07 2020-07-28 珀金埃尔默健康科学有限公司 使用粘土矿物和碱性溶液制备含核酸样品的方法
CA2916990C (en) 2013-06-28 2023-05-23 Streck, Inc. Devices for real-time polymerase chain reaction
US9536304B2 (en) 2013-08-30 2017-01-03 Dairy Quality Inc. Determining pathogens based on an image of somatic cells in a fluid sample
US10436680B2 (en) * 2013-10-15 2019-10-08 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method
US11504709B2 (en) * 2013-10-15 2022-11-22 Kianoosh Peyvan Capture, disruption, and extraction apparatus and method
US10294512B2 (en) 2013-10-21 2019-05-21 Sung-Chun Kim Method and apparatus for analyzing biomolecules by using oligonucleotide
EP3062252A4 (de) 2013-10-22 2017-06-07 KIM, Sung-Chun Marker zur erzeugung von bindungsinformationen auf biomolekülen und nukleinsäuren, herstellungsverfahren dafür sowie verfahren und vorrichtung zur analyse von biomolekülen damit
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US10191071B2 (en) 2013-11-18 2019-01-29 IntegenX, Inc. Cartridges and instruments for sample analysis
EP2878375A1 (de) * 2013-11-29 2015-06-03 Genewave Mikrofluidische Kartusche für molekulare Diagnose, Andockstation mit solch einer mikrofluidischen Kartusche und Verfahren zur Analyse einer biologischen Probe
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
US10634590B2 (en) 2014-03-11 2020-04-28 Emd Millipore Corporation IHC, tissue slide fluid exchange disposable and system
CN204727866U (zh) * 2014-03-31 2015-10-28 博奥生物集团有限公司 一种集核酸扩增和微阵列检测于一体的微流控装置
DE102014105437A1 (de) 2014-04-16 2015-10-22 Amodia Bioservice Gmbh Mikrofluidik-Modul und Kassette für die immunologische und molekulare Diagnostik in einem Analyseautomaten
ES2887222T3 (es) 2014-04-24 2021-12-22 Lucira Health Inc Detección colorimétrica de amplificación de ácido nucleico
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
CA3127071A1 (en) 2014-05-27 2015-12-03 Alex Aravanis Systems and methods for biochemical analysis including a base instrument and a removable cartridge
US10093918B2 (en) 2014-06-04 2018-10-09 Lucigen Corporation Sample collection and analysis devices
CN108064315B (zh) 2014-08-22 2022-01-18 西菲伊德公司 检测流感的方法
US20160067709A1 (en) * 2014-09-05 2016-03-10 Htc Corporation Micro-channel module
US9701933B2 (en) * 2014-09-19 2017-07-11 Sarfaraz K. Niazi Harvesting and purification or perfusion yielder (HAPPY) device
JP6675168B2 (ja) * 2014-09-30 2020-04-01 キヤノンメディカルシステムズ株式会社 核酸検査装置
US9486590B2 (en) 2014-09-29 2016-11-08 Fenwal, Inc. Automatic purging of air from a fluid processing system
EP3209410A4 (de) 2014-10-22 2018-05-02 IntegenX Inc. Systeme und verfahren zur automatisierten vorbereitung, verarbeitung und analyse von proben
WO2016069853A2 (en) 2014-10-30 2016-05-06 Cepheid Methods of detecting ebola
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
US9365044B1 (en) * 2014-12-12 2016-06-14 Funai Electric Co., Ltd. Printhead cartridge with hydrophobic coating
US10273534B2 (en) 2014-12-15 2019-04-30 Cepheid Exponential base-greater-than-2 nucleic acid amplification
CN107429281B (zh) 2014-12-31 2022-05-27 维斯比医学公司 用于分子诊断测试的装置和方法
GB201501705D0 (en) 2015-02-02 2015-03-18 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
GB2531615B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
GB2531616B (en) * 2015-02-02 2017-11-22 Atlas Genetics Ltd Instrument for performing a diagnostic test on a fluidic cartridge
WO2016168747A1 (en) * 2015-04-16 2016-10-20 Terumo Bct, Inc. Automated protein production and cell lysing
WO2016205233A2 (en) * 2015-06-15 2016-12-22 Cepheid Integrated purification and measurement of dna methylation and co-measurement of mutations and/or mrna expression levels in an automated reaction cartridge
US10233491B2 (en) 2015-06-19 2019-03-19 IntegenX, Inc. Valved cartridge and system
CN116206744A (zh) 2015-06-25 2023-06-02 甘布罗伦迪亚股份公司 具有分布式数据库的医疗装置系统和方法
AU2016298048B2 (en) 2015-07-24 2022-08-04 Cepheid Compositions and methods for DNA and RNA extraction from tissue samples
WO2017062991A1 (en) * 2015-10-09 2017-04-13 Silicon Biodevices, Inc. Industrial design of stand-alone assay system
WO2017116694A1 (en) * 2015-12-29 2017-07-06 3M Innovative Properties Company Method and system for detecting microorganisms in large-volume samples
US10625009B2 (en) 2016-02-17 2020-04-21 Baxter International Inc. Airtrap, system and method for removing microbubbles from a fluid stream
US11291995B2 (en) 2016-03-14 2022-04-05 Lucira Health, Inc. Selectively vented biological assay devices and associated methods
CN106483180A (zh) * 2016-03-31 2017-03-08 广州万孚生物技术股份有限公司 血气分析仪及其血气生化测试卡
CN117269282A (zh) * 2016-03-31 2023-12-22 深圳市理邦精密仪器股份有限公司 测试卡组件及血气分析仪
WO2017197040A1 (en) * 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
US10774393B2 (en) 2016-05-20 2020-09-15 Roche Molecular Systems, Inc. Cell surface marker depletion in a sample processing device
DE102016209904A1 (de) * 2016-06-06 2017-12-07 Robert Bosch Gmbh Verfahren und mikrofluidische Vorrichtung zum Verarbeiten einer Probe biologischen Materials
CA3026646A1 (en) 2016-06-07 2017-12-14 Cepheid Thermostable polymerase inhibitor compositions and methods
CN110325652A (zh) 2016-06-29 2019-10-11 易捷仪器诊断股份有限公司 使用流动池检测分子的装置和方法
EP3510396B1 (de) 2016-09-08 2021-12-08 Hemex Health, Inc. Diagnosesystem
US10349589B2 (en) 2016-09-08 2019-07-16 Hemex Health, Inc. Diagnostics systems and methods
US11478791B2 (en) 2016-09-12 2022-10-25 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11376581B2 (en) 2016-09-12 2022-07-05 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11426735B2 (en) 2016-09-12 2022-08-30 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
SG10201913814QA (en) * 2016-09-12 2020-03-30 Delta Electronics Intl Singapore Pte Ltd Nucleic Acid Analysis Apparatus
EP3301445B1 (de) * 2016-09-30 2020-03-18 ARKRAY, Inc. Verfahren zur magnetischen etikettierung von partikeln
WO2018065115A1 (en) * 2016-10-07 2018-04-12 Boehringer Ingelheim Vetmedica Gmbh Method for controlling an analysis device and analysis system
JP2019537706A (ja) 2016-10-07 2019-12-26 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ サンプルを検査するための方法及び分析システム
EP3523032A2 (de) * 2016-10-07 2019-08-14 Boehringer Ingelheim Vetmedica GmbH Kartusche zum testen einer probe
ES2822089T3 (es) 2016-10-07 2021-04-29 Boehringer Ingelheim Vetmedica Gmbh Dispositivo de análisis y método para examinar una muestra
US10422012B2 (en) 2016-10-10 2019-09-24 Roche Molecular Systems, Inc. Devices comprising bacteriophage PHI6 internal control compositions
USD814652S1 (en) * 2016-10-14 2018-04-03 Spartan Bioscience In. Cartridge
IL290157B2 (en) 2016-10-14 2023-09-01 Illumina Inc cartridge kit
EP3548603A4 (de) 2016-11-29 2020-10-28 S2 Genomics, Inc. Verfahren und vorrichtung zur verarbeitung von gewebeproben
KR102479432B1 (ko) 2016-12-12 2022-12-20 세페이드 자동화 반응 카트리지에서 DNA 메틸화의 통합 정제 및 측정 및 돌연변이 및/또는 mRNA 발현도의 동시 측정
TWI611171B (zh) 2016-12-14 2018-01-11 財團法人工業技術研究院 生物樣品處理裝置
EP3559951B1 (de) 2016-12-21 2022-01-12 Gambro Lundia AB Medizinproduktsystem mit informationstechnologieinfrastruktur mit sicherer cluster-domäne zur unterstützung einer externen domäne
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
JP2018174826A (ja) * 2017-04-14 2018-11-15 キヤノンメディカルシステムズ株式会社 核酸調製器具
US20190093155A1 (en) 2017-05-25 2019-03-28 Roche Molecular Systems, Inc. Multiplex Nucleic Acid Amplification Assay
US11602750B2 (en) 2017-05-30 2023-03-14 Roche Molecular Systems, Inc. Customizable sample processing device
WO2019005833A1 (en) * 2017-06-26 2019-01-03 Mendoza Estevan SAMPLE FILTERING DEVICE
JP7120802B2 (ja) * 2017-07-20 2022-08-17 株式会社神戸製鋼所 流体流通装置及びその流通異常検知方法
US11207674B2 (en) 2017-08-09 2021-12-28 Biogx, Inc. Method of customizing a universal reagent cartridge with a lyophilized target-specific reagent
US10549275B2 (en) 2017-09-14 2020-02-04 Lucira Health, Inc. Multiplexed biological assay device with electronic readout
JP2019075997A (ja) * 2017-10-20 2019-05-23 花王株式会社 吸収性物品に移行した微生物から核酸又はタンパク質を抽出する方法
WO2019083844A1 (en) * 2017-10-23 2019-05-02 Cytochip Inc. DEVICES AND METHOD FOR MEASURING TARGET ANALYTES AND PARTICLES
ES2960530T3 (es) 2017-10-31 2024-03-05 Hoffmann La Roche Partículas magnéticas mejoradas y usos de las mismas
US11162130B2 (en) 2017-11-09 2021-11-02 Visby Medical, Inc. Portable molecular diagnostic device and methods for the detection of target viruses
CN111712581A (zh) * 2017-12-15 2020-09-25 生米公司 用于分析样品的便携式装置和方法
JP7052044B2 (ja) 2017-12-19 2022-04-11 エフ．ホフマン－ラ ロシュ アーゲー 試料処理デバイスにおいて脆いシールを製造する方法
KR102065650B1 (ko) * 2017-12-28 2020-02-11 에스디 바이오센서 주식회사 카트리지를 이용한 핵산 추출 방법
KR102065649B1 (ko) * 2017-12-28 2020-01-13 에스디 바이오센서 주식회사 핵산 추출용 카트리지의 피스톤
US11147897B2 (en) * 2018-04-06 2021-10-19 American Sterilizer Company Sterilization process challenge device
CN112261975B (zh) * 2018-04-11 2022-09-13 印第安纳大学理事会 用于质谱分析的盒、系统和方法
CN109874316B (zh) * 2018-05-25 2022-10-11 江苏汇先医药技术有限公司 用于从样本中富集筛选目标物例如细胞、细菌或生物分子的装置
JP2021525550A (ja) 2018-06-01 2021-09-27 エス２ ゲノミクス インコーポレイテッド 組織サンプルを処理するための方法および装置
DE102018210069A1 (de) * 2018-06-21 2019-12-24 Robert Bosch Gmbh Mikrofluidische Vorrichtung, Verfahren zu deren Herstellung und Verwendung
US10974240B2 (en) * 2018-07-06 2021-04-13 Qorvo Us, Inc. Fluidic channel for a cartridge
EP3820610A1 (de) * 2018-07-12 2021-05-19 Luminex Corporation Systeme und verfahren zur durchführung variabler probenvorbereitung und analyseverfahren
WO2020070007A1 (en) 2018-10-01 2020-04-09 Boehringer Ingelheim Vetmedica Gmbh Peristaltic pump and analyzer for testing a sample
CA3118000A1 (en) 2018-10-29 2020-05-07 Cepheid Exponential base-3 nucleic acid amplification with reduced amplification time using nested overlapping primers
WO2020112550A1 (en) 2018-11-30 2020-06-04 Illumina, Inc. Systems and methods for active warming of a cartridge
USD920534S1 (en) 2018-12-21 2021-05-25 CanaryQ, Inc. Blood sample filtration device
USD907232S1 (en) 2018-12-21 2021-01-05 Lucira Health, Inc. Medical testing device
CN113646088B (zh) * 2019-03-05 2023-07-04 卢西拉健康公司 对流体室的无气泡液体填充
JP2022527250A (ja) 2019-03-21 2022-06-01 バイオミーム インコーポレイテッド 多機能性分析デバイス
US11918996B2 (en) * 2019-04-15 2024-03-05 Genecapture, Inc. Integrated cartridge for sample homogenization and nucleic acid fragmentation
KR20220025730A (ko) * 2019-06-25 2022-03-03 헤멕스 헬스, 인크. 외부 초음파 처리
US11740203B2 (en) 2019-06-25 2023-08-29 Hemex Health, Inc. Diagnostics systems and methods
WO2021011512A1 (en) 2019-07-15 2021-01-21 Lexagene, Inc. Sample preparation cartridges and apparatuses
US10820847B1 (en) 2019-08-15 2020-11-03 Talis Biomedical Corporation Diagnostic system
US20220401886A1 (en) * 2019-11-19 2022-12-22 University Of Cincinnati Devices and methods for concentration of analytes
US11733258B2 (en) 2019-12-10 2023-08-22 Industrial Technology Research Institute Nucleic acid extracting device
US11254979B2 (en) 2020-06-01 2022-02-22 Shaheen Innovations Holding Limited Systems and devices for infectious disease screening
US11730193B2 (en) 2019-12-15 2023-08-22 Shaheen Innovations Holding Limited Hookah device
US11352675B2 (en) 2020-01-03 2022-06-07 Visby Medical, Inc. Devices and methods for antibiotic susceptability testing
USD953561S1 (en) 2020-05-05 2022-05-31 Lucira Health, Inc. Diagnostic device with LED display
IL298679A (en) * 2020-06-01 2023-01-01 Shaheen Innovations Holding Ltd Infectious disease screening system
EP3919176A1 (de) * 2020-06-01 2021-12-08 Shaheen Innovations Holding Limited Testvorrichtungen und systeme zum screening auf infektionskrankheiten
GB2611468A (en) * 2020-06-01 2023-04-05 Shaheen Innovations Holding Ltd An infectious disease screening device
EP3919175A1 (de) * 2020-06-01 2021-12-08 Shaheen Innovations Holding Limited Systeme und vorrichtungen zur untersuchung infektiöser erkrankungen
USD962470S1 (en) 2020-06-03 2022-08-30 Lucira Health, Inc. Assay device with LCD display
CA3181510A1 (en) * 2020-06-11 2021-12-16 Siemens Healthcare Diagnostics Inc. Method and analyzer to correct for unknown interferences in a patient blood sample
CA3183566A1 (en) 2020-06-26 2021-12-30 Victor Chu Methods of detecting sars-cov-2, influenza, and rsv
CN116457099A (zh) 2020-09-18 2023-07-18 生米公司 用于分析样品的便携式装置和方法
US20220106627A1 (en) 2020-10-06 2022-04-07 Cepheid Methods of diagnosing tuberculosis and differentiating between active and latent tuberculosis
KR20230093054A (ko) 2020-10-30 2023-06-26 세페이드 교체 가능한 처리 모듈 및 원격 모니터링을 갖는 진단 분석 시스템
DE102020134836B3 (de) 2020-12-23 2022-03-24 LCTech GmbH Extraktionssystem zur Extraktion von Analyten aus einer Probe
AU2021410016A1 (en) * 2020-12-24 2023-07-20 Invivoscribe Inc. Chemical processing system, instrument and sample cartridge
WO2022182837A1 (en) * 2021-02-26 2022-09-01 Collins James J Devices and methods for rapid nucleic acid preparation and detection
US20220298572A1 (en) 2021-03-16 2022-09-22 Cepheid Compositions and methods for discriminating bacterial and viral infections in a human subject
WO2022251508A1 (en) * 2021-05-28 2022-12-01 Proof Diagnostics Reaction cartridge
TWI785636B (zh) 2021-06-07 2022-12-01 新加坡商克雷多生醫有限公司 檢測卡匣
CN113308369A (zh) * 2021-07-14 2021-08-27 北京乐普智慧医疗科技有限公司 一种核酸检测卡盒及其组装工艺
US20230166256A1 (en) * 2021-09-29 2023-06-01 Fremonta Corporation Methods and systems for sample processing utilizing filter aid materials and aggregating samplers for equipment
WO2023070123A1 (en) 2021-10-22 2023-04-27 Cepheid Compositions and methods of diagnosing and treating tuberculosis
JP2023063027A (ja) * 2021-10-22 2023-05-09 株式会社エンプラス 流体取扱装置およびこれを含む流体取扱システム
USD1014780S1 (en) 2022-04-15 2024-02-13 Instrumentation Laboratory Co. Cuvette

Family Cites Families (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US955351A (en) * 1909-05-13 1910-04-19 Palmer I E Co Resilient bottom for couch-hammocks, &c.
US2856148A (en) * 1952-02-08 1958-10-14 Vickers Electrical Co Ltd Valve assembly
GB938163A (en) 1960-09-20 1963-10-02 Boots Pure Drug Co Ltd Improvements in or relating to particle size reduction or cellular disruption
US3448890A (en) 1966-05-02 1969-06-10 Lusteroid Container Co Inc Plastic tube construction
US3799742A (en) 1971-12-20 1974-03-26 C Coleman Miniaturized integrated analytical test container
US4180383A (en) 1975-04-07 1979-12-25 Becton, Dickinson And Company Chamber holder for immobilized immunoadsorbent
US4336719A (en) * 1980-07-11 1982-06-29 Panametrics, Inc. Ultrasonic flowmeters using waveguide antennas
US4426451A (en) 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
US4335719A (en) * 1981-02-04 1982-06-22 Johnston Samuel R Irrigation device
SE8102316L (sv) 1981-04-10 1982-10-11 Pharmacia Diagnostics Ab Anordning for genomforande av analyser
AU570439B2 (en) 1983-03-28 1988-03-17 Compression Labs, Inc. A combined intraframe and interframe transform coding system
US4615984A (en) 1984-02-23 1986-10-07 Becton Dickinson & Company Dissociation of ligand-binder complex using ultrasound
US4963498A (en) 1985-08-05 1990-10-16 Biotrack Capillary flow device
CA1296604C (en) * 1986-03-20 1992-03-03 Kathleen Murphy Method for releasing rna and dna from cells
GB2191110B (en) 1986-06-06 1989-12-06 Plessey Co Plc Chromatographic separation device
US4789628A (en) 1986-06-16 1988-12-06 Vxr, Inc. Devices for carrying out ligand/anti-ligand assays, methods of using such devices and diagnostic reagents and kits incorporating such devices
US4915812A (en) 1986-06-20 1990-04-10 Molecular Devices Corporation Zero volume cell
JPS63105977A (ja) 1986-10-22 1988-05-11 Ise Kagaku Kogyo Kk 薄膜を形成させる方法
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
CH667599A5 (fr) * 1986-12-11 1988-10-31 Battelle Memorial Institute Enceinte destinee a contenir un milieu liquide.
US4918025A (en) 1987-03-03 1990-04-17 Pb Diagnostic Systems, Inc. Self contained immunoassay element
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
DD284131A7 (de) 1987-07-10 1990-11-07 �����@�������`����k�� Verfahren und vorrichtung zur herstellung bioaktiver suspensionen
US4908318A (en) 1987-09-04 1990-03-13 Integrated Genetics, Inc. Nucleic acid extraction methods
US4846440A (en) * 1987-09-30 1989-07-11 Spectra Physics Valve with metal diaphragm and flat surface valve body
US4923978A (en) * 1987-12-28 1990-05-08 E. I. Du Pont De Nemours & Company Process for purifying nucleic acids
US4921952A (en) 1988-01-21 1990-05-01 The United States Of America As Represented By The United States Department Of Energy Nucleic acid isolation process
SE8801299L (sv) 1988-04-08 1989-10-09 Bertil Hoeoek Mikromekanisk envaegsventil
US4983523A (en) 1988-04-08 1991-01-08 Gene-Trak Systems Methods for preparing sample nucleic acids for hybridization
US5374533A (en) 1988-05-10 1994-12-20 Tetjin Limited Method for determining chondrocalcin
US4908112A (en) 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
FR2634892B1 (fr) 1988-07-28 1990-09-14 Guigan Jean Dispositif pour la realisation d'analyses biologiques par detection immuno-enzymatique d'anticorps ou d'antigenes dans un serum
JP2671135B2 (ja) 1988-08-01 1997-10-29 東湘電機株式会社 細胞の超音波破砕装置
US5395502A (en) * 1988-11-14 1995-03-07 Anthony R. Torres Apparatus for performing and universally detecting capillary isoelectric focusing without mobilization using concentration gradient imaging systems
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
JPH02234600A (ja) * 1989-03-07 1990-09-17 Mitsubishi Mining & Cement Co Ltd 圧電変換素子
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5207988A (en) 1989-07-06 1993-05-04 The Cleveland Clinic Foundation Apparatus for detecting and quantifying clot lysis and establishing optimum medication and dosages
US5124444A (en) 1989-07-24 1992-06-23 Microprobe Corporation Lactam-containing compositions and methods useful for the extraction of nucleic acids
US5231015A (en) 1989-10-18 1993-07-27 Eastman Kodak Company Methods of extracting nucleic acids and pcr amplification without using a proteolytic enzyme
AU642444B2 (en) 1989-11-30 1993-10-21 Mochida Pharmaceutical Co., Ltd. Reaction vessel
US5858188A (en) 1990-02-28 1999-01-12 Aclara Biosciences, Inc. Acrylic microchannels and their use in electrophoretic applications
US5770029A (en) 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
US5582829A (en) 1990-04-05 1996-12-10 Rx Technologies, Inc. Sonicated borrelia burgdorferi vaccine
US5143084A (en) 1990-05-24 1992-09-01 Spacelabs, Inc. Disposable cartridge for sampling and analyzing body fluids
US5114858A (en) 1990-06-26 1992-05-19 E. I. Du Pont De Nemours And Company Cellular component extraction process in a disposable filtration vessel
DE4126436A1 (de) 1990-09-17 1992-03-19 Abion Ohg Einwegreaktionsgefaess fuer die festphasenimmunanalytik und verfahren zur messung von ueber immunreaktionen bestimmbaren komponenten
US5652141A (en) * 1990-10-26 1997-07-29 Oiagen Gmbh Device and process for isolating nucleic acids from cell suspension
US5352777A (en) 1990-12-26 1994-10-04 Pioneer Hi-Bred International, Inc. DNA isolation from animal cells
SE9100392D0 (sv) 1991-02-08 1991-02-08 Pharmacia Biosensor Ab A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means
US5264184A (en) 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
US5422241A (en) 1991-07-03 1995-06-06 Ambion, Inc. Methods for the recovery of nucleic acids from reaction mixtures
US5155018A (en) 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5329000A (en) 1991-10-31 1994-07-12 Becton, Dickinson And Company Purification of DNA with silicon tetrahydrazide
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
EP0555798B1 (de) 1992-02-13 1999-05-06 Becton, Dickinson and Company Celithydrat und Reinigung von DNS
US5223219A (en) 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US6953676B1 (en) 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5296375A (en) 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5304487A (en) 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5409586A (en) 1992-08-26 1995-04-25 Hitachi, Ltd. Method for analyzing nucleic acid or protein and apparatus therefor
US5639423A (en) 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5422271A (en) 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5399486A (en) 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
US5798215A (en) 1993-02-18 1998-08-25 Biocircuits Corporation Device for use in analyte detection assays
US5427663A (en) 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
AU7563294A (en) 1993-08-24 1995-03-21 Metrika Laboratories, Inc. Novel disposable electronic assay device
US5438127A (en) 1993-09-27 1995-08-01 Becton Dickinson And Company DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane
US5438129A (en) 1993-09-27 1995-08-01 Becton Dickinson And Company DNA purification by solid phase extraction using partially fluorinated aluminum hydroxide adsorbant
DK0725682T3 (da) 1993-10-28 2002-07-15 Houston Advanced Res Ct Mikrofremstillet, porøst gennemløbsapparat til diskret påvisning af bindingsreaktioner
US6129828A (en) 1996-09-06 2000-10-10 Nanogen, Inc. Apparatus and methods for active biological sample preparation
US5976824A (en) 1993-11-24 1999-11-02 Abbott Laboratories Method and apparatus for collecting a cell sample from a liquid specimen
EP0671626B1 (de) 1994-03-08 2000-01-12 Zeptosens AG Vorrichtung und Verfahren, die Bioaffinitätsassay und elektrophoretische Auftrennung kombinieren
US5580435A (en) 1994-06-10 1996-12-03 The Board Of Trustees Of The Leland Stanford Junior University System for detecting components of a sample in electrophoretic separation
DE4420732A1 (de) 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
US5639428A (en) 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US6093520A (en) 1994-09-09 2000-07-25 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College High aspect ratio microstructures and methods for manufacturing microstructures
US5707799A (en) 1994-09-30 1998-01-13 Abbott Laboratories Devices and methods utilizing arrays of structures for analyte capture
US5641400A (en) 1994-10-19 1997-06-24 Hewlett-Packard Company Use of temperature control devices in miniaturized planar column devices and miniaturized total analysis systems
US5500071A (en) 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
CA2203282A1 (en) 1994-10-22 1996-05-02 Robert George Godfrey Holmes Method and apparatus for diffusive transfer between immiscible fluids
WO1996014400A1 (en) * 1994-11-08 1996-05-17 Bradley Michael John Stringer Human cell-lines
AUPM934994A0 (en) * 1994-11-09 1994-12-01 Commonwealth Scientific And Industrial Research Organisation Particle property measurement
US5585069A (en) 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
IT1272932B (it) 1995-01-24 1997-07-01 Pier Giorgio Righetti Reattore ad enzima immobilizzato
CN1661115A (zh) 1995-03-10 2005-08-31 梅索磅秤技术有限公司 多阵列、多特异性的电化学发光检验
DE19519015C1 (de) 1995-05-24 1996-09-05 Inst Physikalische Hochtech Ev Miniaturisierter Mehrkammer-Thermocycler
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US5955351A (en) 1995-07-13 1999-09-21 Gerdes; John C. Self-contained device integrating nucleic acid extraction amplification and detection
KR970706902A (ko) 1995-09-12 1997-12-01 로드릭 리차드 제이 Dna 증폭 및 검정 방법 및 장치(device and method for dna amplification and assay)
US5660029A (en) * 1995-11-21 1997-08-26 King; Sidney E. Capsule filler
US5705018A (en) 1995-12-13 1998-01-06 Hartley; Frank T. Micromachined peristaltic pump
EP0780611A1 (de) * 1995-12-22 1997-06-25 Applied Materials, Inc. Durchflussregelventil
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US5846727A (en) 1996-06-06 1998-12-08 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Microsystem for rapid DNA sequencing
US5863801A (en) 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US5779868A (en) 1996-06-28 1998-07-14 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
WO1998000705A1 (en) 1996-06-28 1998-01-08 Caliper Technologies Corporation Electropipettor and compensation means for electrophoretic bias
US5946673A (en) * 1996-07-12 1999-08-31 Francone; Frank D. Computer implemented machine learning and control system
EP0826412A3 (de) 1996-08-26 1999-06-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Verfahren zur Herstellung von Filterelementen und die damit hergestellen Filterelemente
US6716511B2 (en) * 1996-09-16 2004-04-06 Bp Corporation North America Inc. Propylene polymer fibers and yarns
US5874046A (en) 1996-10-30 1999-02-23 Raytheon Company Biological warfare agent sensor system employing ruthenium-terminated oligonucleotides complementary to target live agent DNA sequences
US5882903A (en) 1996-11-01 1999-03-16 Sarnoff Corporation Assay system and method for conducting assays
US5921678A (en) 1997-02-05 1999-07-13 California Institute Of Technology Microfluidic sub-millisecond mixers
ES2544455T3 (es) 1997-02-28 2015-08-31 Cepheid Montaje para reacción química con intercambio de calor, ópticamente interrogada
GB2337113B (en) 1997-02-28 2001-03-21 Burstein Lab Inc Laboratory in a disk
EP0988529B1 (de) 1997-04-25 2013-06-12 Caliper Life Sciences, Inc. Mikrofluidische geräte mit verbesserten kanalgeometrien
US6156273A (en) 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
US5869004A (en) 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
WO1999009042A2 (en) * 1997-08-13 1999-02-25 Cepheid Microstructures for the manipulation of fluid samples
US6117290A (en) * 1997-09-26 2000-09-12 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US6106779A (en) * 1997-10-02 2000-08-22 Biosite Diagnostics, Inc. Lysis chamber for use in an assay device
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
CA2312102C (en) * 1997-12-24 2007-09-04 Cepheid Integrated fluid manipulation cartridge
US6194222B1 (en) * 1998-01-05 2001-02-27 Biosite Diagnostics, Inc. Methods for monitoring the status of assays and immunoassays
US5993872A (en) * 1998-08-12 1999-11-30 Reno Rolle Deep fat fryer with ultrasonic rotational basket
US6100084A (en) * 1998-11-05 2000-08-08 The Regents Of The University Of California Micro-sonicator for spore lysis
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US6261431B1 (en) 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
US6056269A (en) * 1999-01-15 2000-05-02 Hewlett-Packard Company Microminiature valve having silicon diaphragm
US6315957B1 (en) 1999-01-15 2001-11-13 Pharmacopeia, Inc. Article comprising a filter pocket-plate
US6138990A (en) * 1999-03-25 2000-10-31 Dxl Usa Inc. Flow control valve assembly for mass flow controller
FR2791697B1 (fr) 1999-04-01 2003-02-28 Biomerieux Sa Appareil et procede de lyse par ultrasons de cellules biologiques
US20040200909A1 (en) 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
JP4078073B2 (ja) 1999-05-28 2008-04-23 シーフィード 流体試料分析装置および方法
US6878540B2 (en) * 1999-06-25 2005-04-12 Cepheid Device for lysing cells, spores, or microorganisms
US6942169B2 (en) 2001-06-06 2005-09-13 Integrated Sensing Systems Micromachined lysing device and method for performing cell lysis
US6739531B2 (en) 2001-10-04 2004-05-25 Cepheid Apparatus and method for rapid disruption of cells or viruses

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JP4078073B2 (ja) 2008-04-23
WO2000073413A3 (en) 2001-01-25
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WO2000073413A9 (en) 2002-01-24
ATE302263T1 (de) 2005-09-15
EP1180135A2 (de) 2002-02-20
EP1180135B1 (de) 2005-08-17
US20120171758A1 (en) 2012-07-05
AU780073B2 (en) 2005-02-24
WO2000073412A2 (en) 2000-12-07
US20010012612A1 (en) 2001-08-09
DE60014676D1 (de) 2004-11-11
US9789481B2 (en) 2017-10-17
AU782343B2 (en) 2005-07-21
US8580559B2 (en) 2013-11-12
US9156032B2 (en) 2015-10-13
CA2373249A1 (en) 2000-12-07
US6783736B1 (en) 2004-08-31
AU5170700A (en) 2000-12-18
CA2373249C (en) 2011-08-02
US20040166031A1 (en) 2004-08-26
US6881541B2 (en) 2005-04-19
US20080057572A1 (en) 2008-03-06
AU5301000A (en) 2000-12-18
CA2374423C (en) 2013-04-09
ATE278771T1 (de) 2004-10-15
JP4022069B2 (ja) 2007-12-12
DE60022025T2 (de) 2006-06-29
US20020019060A1 (en) 2002-02-14
EP1208189A2 (de) 2002-05-29
JP2003522521A (ja) 2003-07-29
JP2003501018A (ja) 2003-01-14
DE60014676T2 (de) 2005-11-17
EP1208189B1 (de) 2004-10-06
CA2374423A1 (en) 2000-12-07
WO2000073413A2 (en) 2000-12-07
US20120009667A1 (en) 2012-01-12

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