DE60018865D1 - Vorrichtung zum Abscheuern der Haut - Google Patents

Vorrichtung zum Abscheuern der Haut

Info

Publication number
DE60018865D1
DE60018865D1 DE60018865T DE60018865T DE60018865D1 DE 60018865 D1 DE60018865 D1 DE 60018865D1 DE 60018865 T DE60018865 T DE 60018865T DE 60018865 T DE60018865 T DE 60018865T DE 60018865 D1 DE60018865 D1 DE 60018865D1
Authority
DE
Germany
Prior art keywords
scouring
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60018865T
Other languages
English (en)
Other versions
DE60018865T2 (de
Inventor
Sage, Jr
Carl Randolph Bock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE60018865D1 publication Critical patent/DE60018865D1/de
Application granted granted Critical
Publication of DE60018865T2 publication Critical patent/DE60018865T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/54—Chiropodists' instruments, e.g. pedicure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320004—Surgical cutting instruments abrasive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles
DE60018865T 1999-09-24 2000-08-16 Vorrichtung zum Abscheuern der Haut Expired - Lifetime DE60018865T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US405488 1999-09-24
US09/405,488 US6835184B1 (en) 1999-09-24 1999-09-24 Method and device for abrading skin

Publications (2)

Publication Number Publication Date
DE60018865D1 true DE60018865D1 (de) 2005-04-28
DE60018865T2 DE60018865T2 (de) 2006-04-13

Family

ID=23603908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60018865T Expired - Lifetime DE60018865T2 (de) 1999-09-24 2000-08-16 Vorrichtung zum Abscheuern der Haut

Country Status (8)

Country Link
US (4) US6835184B1 (de)
EP (1) EP1086719B1 (de)
JP (1) JP2001157715A (de)
AU (1) AU778277B2 (de)
CA (1) CA2316534C (de)
DE (1) DE60018865T2 (de)
ES (1) ES2235723T3 (de)
SG (1) SG97921A1 (de)

Families Citing this family (250)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US7048723B1 (en) * 1998-09-18 2006-05-23 The University Of Utah Research Foundation Surface micromachined microneedles
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US6331266B1 (en) * 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US6595947B1 (en) * 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
US6565532B1 (en) 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7131987B2 (en) * 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6743215B2 (en) * 2001-04-06 2004-06-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and cellulite reduction
CN100349632C (zh) * 2001-04-20 2007-11-21 阿尔扎公司 具有包含有益药剂的涂层的微小突出物阵列
EP1256316A1 (de) 2001-05-07 2002-11-13 Move2Health B.V. Tragbare Vorrichtung mit einem Beschleunigungssensor und ein Verfahren zur Erzeugung von Befehlen oder Ratschläge
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
ATE497731T1 (de) 2001-06-12 2011-02-15 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1404235A4 (de) 2001-06-12 2008-08-20 Pelikan Technologies Inc Verfahren und gerät für eine auf einer blutentnahmekartusche integrierte lanzettenvorrichtung
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
EP1404233B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP4149911B2 (ja) 2001-06-12 2008-09-17 ペリカン テクノロジーズ インコーポレイテッド 電気式ランセットアクチュエータ
CA2457804C (en) * 2001-08-13 2012-10-16 University Of Rochester Transcutaneous immunization against papillomavirus with papillomavirus virus-like particles
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
EP1424928B1 (de) * 2001-09-14 2019-09-11 Corium International, Inc. Verfahren zur hautabschälung mit dicht gepackten mikrostrukturen
WO2003051284A2 (en) * 2001-10-29 2003-06-26 Becton, Dickinson And Company Method and device for the delivery of a substance
US20040120964A1 (en) * 2001-10-29 2004-06-24 Mikszta John A. Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
GB0201736D0 (en) * 2002-01-25 2002-03-13 Glaxo Group Ltd DNA dosage forms
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
WO2003090816A2 (en) * 2002-04-24 2003-11-06 Kevin Marchitto Feedback control device for transcutaneous drug delivery and uses therefor
EP3375463A1 (de) 2002-05-06 2018-09-19 Becton, Dickinson and Company Verfahren und vorrichtung zur steuerung von arzneimittelpharmakokinetik
MXPA05000597A (es) * 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
CA2497154C (en) * 2002-08-29 2012-01-03 Becton, Dickinson And Company Substance delivery via a rotating microabrading surface
WO2004028379A1 (en) * 2002-09-25 2004-04-08 Flock, Stephen, T. Microsurgical tissue treatment system
CA2444211C (en) * 2002-10-11 2013-11-19 Dermal Therapy (Barbados) Inc. Determination of biological conditions using impedance measurements
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
ATE503491T1 (de) * 2003-02-13 2011-04-15 Becton Dickinson Co Verbesserte anthraximpfstoffe und abgabeverfahren
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
US7087063B2 (en) * 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
ES2347248T3 (es) 2003-05-30 2010-10-27 Pelikan Technologies Inc. Procedimiento y aparato para la inyeccion de fluido.
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
TW200518771A (en) * 2003-06-30 2005-06-16 Alza Corp Formulations for coated microprojections containing non-volatile counterions
CN1874720B (zh) * 2003-09-03 2010-11-17 生命修复国际股份有限公司 个人诊断装置
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
CN1897898A (zh) 2003-10-24 2007-01-17 阿尔扎公司 用于增强透皮药物传递的预处理方法和系统
ES2377647T3 (es) * 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
US8017145B2 (en) 2003-12-22 2011-09-13 Conopco, Inc. Exfoliating personal care wipe article containing an array of projections
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
GB0402131D0 (en) * 2004-01-30 2004-03-03 Isis Innovation Delivery method
US20070191761A1 (en) * 2004-02-23 2007-08-16 3M Innovative Properties Company Method of molding for microneedle arrays
US7591618B2 (en) 2004-02-25 2009-09-22 Agency For Science, Technology And Research Machining method for micro abraders and micro abraders produced thereby
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
WO2005096981A2 (en) * 2004-04-01 2005-10-20 The General Hospital Corporation Method and apparatus for dermatological treatment
US7842029B2 (en) * 2004-05-07 2010-11-30 Aesthera Apparatus and method having a cooling material and reduced pressure to treat biological external tissue
US8571648B2 (en) * 2004-05-07 2013-10-29 Aesthera Apparatus and method to apply substances to tissue
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
EP1751546A2 (de) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Bedruckbares wassergel für biosensoren
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US20060100567A1 (en) * 2004-07-30 2006-05-11 Rocky Mountain Biosystems, Inc Microsurgical tissue treatment system
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
WO2006055795A1 (en) * 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
US7373820B1 (en) 2004-11-23 2008-05-20 James Terry L Accelerometer for data collection and communication
ATE468961T1 (de) * 2004-12-07 2010-06-15 3M Innovative Properties Co Verfahren zum formen einer mikronadel
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006105146A2 (en) 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
KR101762424B1 (ko) 2005-05-09 2017-07-28 테라노스, 인코포레이티드 현장진료 유체 시스템 및 그 용도
US7762960B2 (en) 2005-05-13 2010-07-27 Boston Scientific Scimed, Inc. Biopsy forceps assemblies
US7442029B2 (en) * 2005-05-16 2008-10-28 Asml Netherlands B.V. Imprint lithography
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
JP2006345983A (ja) * 2005-06-14 2006-12-28 Nabtesco Corp 皮膚用針集合体
WO2007002522A1 (en) 2005-06-27 2007-01-04 3M Innovative Properties Company Microneedle cartridge assembly and method of applying
US8376984B2 (en) * 2005-07-14 2013-02-19 Terry L. James Apparatus, system, and method to deliver optimal elements in order to enhance the aesthetic appearance of the skin
JP5000866B2 (ja) * 2005-08-01 2012-08-15 久光製薬株式会社 生体無毒性医薬物運搬用器具
US20070088248A1 (en) * 2005-09-02 2007-04-19 Iomai Corporation Devices for transcutaneous delivery of vaccines and transdermal delivery of drugs and uses thereof
US20080262416A1 (en) * 2005-11-18 2008-10-23 Duan Daniel C Microneedle Arrays and Methods of Preparing Same
WO2007061781A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
WO2007059289A1 (en) * 2005-11-18 2007-05-24 3M Innovative Properties Company Microneedle arrays and methods of preparing same
WO2007064486A1 (en) * 2005-11-30 2007-06-07 3M Innovative Properties Company Microneedle arrays and methods of use thereof
KR20080080492A (ko) * 2005-11-30 2008-09-04 트랜스포트 파마슈티컬스, 인코포레이티드 약제의 자기 투여를 위한 동전기식 전달시스템의애플리케이터 카트리지
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
AU2006235977B2 (en) * 2006-01-05 2008-06-12 Bradnam's Windows & Doors Pty Ltd Security Mesh with Improved Edge Attachment
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US8187422B2 (en) 2006-03-21 2012-05-29 Georgia-Pacific Consumer Products Lp Disposable cellulosic wiper
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
WO2014151104A1 (en) 2013-03-15 2014-09-25 Edge Systems Llc Devices, systems and methods for treating the skin
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US20070287947A1 (en) * 2006-06-06 2007-12-13 Hamlet Murray P Device and Method for Inhibiting Decubitus Ulcers
JP5338021B2 (ja) * 2006-07-04 2013-11-13 凸版印刷株式会社 針状体の製造方法
US8250729B2 (en) * 2006-07-12 2012-08-28 University Of Utah Research Foundation 3D fabrication of needle tip geometry and knife blade
JP2010502267A (ja) * 2006-08-28 2010-01-28 エージェンシー・フォー・サイエンス・テクノロジー・アンド・リサーチ マイクロニードルおよびマイクロニードルの製造方法
WO2008036043A1 (en) * 2006-09-18 2008-03-27 Agency For Science, Technology And Research Needle structures and methods for fabricating needle structures
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
EP2069013A2 (de) 2006-10-02 2009-06-17 Emkinetics, Inc. Verfahren und vorrichtung für magnetische induktionstherapie
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
CA2676221C (en) 2007-01-22 2016-12-20 Corium International, Inc. Applicators for microneedles
US7713196B2 (en) * 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
US20080288004A1 (en) * 2007-05-16 2008-11-20 Genesis Biosystems Corporation Tissue suspension device
US20090012434A1 (en) * 2007-07-03 2009-01-08 Anderson Robert S Apparatus, method, and system to treat a volume of skin
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
US20090048493A1 (en) * 2007-08-17 2009-02-19 James Terry L Health and Entertainment Device for Collecting, Converting, Displaying and Communicating Data
CA2700309A1 (en) * 2007-09-20 2009-03-26 Transport Pharmaceuticals, Inc. Method of enhancing iontophoretic delivery of a peptide
WO2009046227A1 (en) 2007-10-02 2009-04-09 Theranos, Inc. Modular point-of-care devices and uses thereof
US20090093864A1 (en) * 2007-10-08 2009-04-09 Anderson Robert S Methods and devices for applying energy to tissue
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
US8989858B2 (en) 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US8170659B2 (en) 2007-12-05 2012-05-01 The Invention Science Fund I, Llc Method for thermal modulation of neural activity
US8165668B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8180446B2 (en) 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8165669B2 (en) 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8180447B2 (en) 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method for reversible chemical modulation of neural activity
US8170658B2 (en) 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8195287B2 (en) 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
AU2008341030B2 (en) 2007-12-24 2014-04-17 Vaxxas Pty Limited Coating method
US7676332B2 (en) 2007-12-27 2010-03-09 Kersh Risk Management, Inc. System and method for processing raw activity energy expenditure data
KR101836310B1 (ko) 2008-01-04 2018-03-08 엣지 시스템즈 엘엘씨 피부 처리 장치 및 방법
US8814836B2 (en) 2008-01-29 2014-08-26 Edge Systems Llc Devices, systems and methods for treating the skin using time-release substances
US9056193B2 (en) * 2008-01-29 2015-06-16 Edge Systems Llc Apparatus and method for treating the skin
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US20100022497A1 (en) * 2008-07-24 2010-01-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for treating or preventing a cardiovascular disease or condition utilizing estrogen receptor modulators based on APOE allelic profile of a mammalian subject
US20100022494A1 (en) * 2008-07-24 2010-01-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method, device, and kit for maintaining physiological levels of steroid hormone in a subject
US20100022991A1 (en) * 2008-07-24 2010-01-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware System and device for maintaining physiological levels of steroid hormone in a subject
US20100061976A1 (en) * 2008-07-24 2010-03-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject
EP2328530A4 (de) * 2008-08-22 2012-09-12 Us Worldmeds Llc Transdermale freisetzung von apomorphin mittels mikronadeln
TWI475978B (zh) * 2009-01-17 2015-03-11 Ind Tech Res Inst 乾式電極及其製造方法
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
JP2010233339A (ja) * 2009-03-26 2010-10-14 Seiko Epson Corp 圧電モーター、液体噴射装置及び時計
WO2010144545A1 (en) * 2009-06-09 2010-12-16 Vascular Technology, Inc. Soft tissue dissector
WO2011011599A2 (en) * 2009-07-22 2011-01-27 Michael Salzhauer Topical anesthesia inducing (tai) apparatus for inducing topical anesthesia and tai applicators and tai electrodes therefor
NZ599873A (en) 2009-10-19 2014-09-26 Theranos Inc Integrated health data capture and analysis system
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス， インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
US20110319786A1 (en) * 2009-11-20 2011-12-29 Rebello Keith J Apparatus and Method for Measuring Physiological Functions
WO2011084607A1 (en) 2009-12-17 2011-07-14 Bayer Healthcare Llc Transdermal systems, devices, and methods for biological analysis
WO2011075575A1 (en) 2009-12-17 2011-06-23 Bayer Healthcare Llc Transdermal systems, devices, and methods to optically analyze an analyte
CN107115326B (zh) 2010-04-13 2021-01-22 雷尔玛达治疗股份有限公司 1-甲基-n-(2,6-二甲苯基)-2-哌啶甲酰胺的皮肤用药物组合物及其使用方法
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
MX336139B (es) 2010-04-28 2016-01-08 Kimberly Clark Co Dispositivos medicos para la entrega de arn de interferencia corta.
CA2796965C (en) 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Method for increasing permeability of an epithelial barrier
MX345837B (es) 2010-04-28 2017-02-16 Kimberly-Clark Worldwide Incorporated Dispositivo para la entrega de un medicamento para la artritis reumatoide.
AU2011246882B2 (en) 2010-04-28 2016-02-25 Sorrento Therapeutics, Inc. Nanopatterned medical device with enhanced cellular interaction
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル， インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
KR101513288B1 (ko) 2010-05-12 2015-04-17 아이리듬 테크놀로지스, 아이엔씨 장기간 부착을 위한 장치 특징부들 및 설계 요소들
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
GB2482691B (en) * 2010-08-10 2013-08-14 Nemaura Pharma Ltd Structures for transdermal drug delivery
CA3097861A1 (en) 2011-01-21 2012-07-26 Labrador Diagnostics Llc Systems and methods for sample use maximization
US11179553B2 (en) 2011-10-12 2021-11-23 Vaxxas Pty Limited Delivery device
EP3574950B1 (de) 2011-10-27 2021-02-17 Sorrento Therapeutics, Inc. Transdermale freisetzung von hochviskosen bioaktiven wirkstoffen
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
US9522267B2 (en) * 2012-02-08 2016-12-20 Derma Dream Group Ltd Transdermal delivery device
EP2852352B1 (de) 2012-05-04 2021-09-01 Roger Khouri Chirurgische instrumente
US9044582B2 (en) * 2012-06-26 2015-06-02 Franklin J. Chang Apparatus and method for transdermal fluid delivery
MX2015008157A (es) 2012-12-21 2016-02-22 Corium Int Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
JP6198849B2 (ja) 2013-01-24 2017-09-20 アイリズム・テクノロジーズ・インコーポレイテッドｉＲｈｙｔｈｍ Ｔｅｃｈｎｏｌｏｇｉｅｓ，Ｉｎｃ． 生理学的信号をモニターする電子装置、及び該電子装置の部分を除去交換する方法
BR112015019440A8 (pt) 2013-02-20 2019-11-12 Cytrellis Biosystems Inc curativo regulável, kit, uso e método para fortalecimento da pele
ES2921481T3 (es) 2013-03-12 2022-08-26 Corium Inc Aplicadores para microproyecciones
EP2968751B1 (de) 2013-03-15 2022-11-30 Corium, Inc. Mehrfachberührungs-mikroprojektionsapplikatoren
ES2761580T3 (es) 2013-03-15 2020-05-20 Corium Inc Micromatrices para suministro de agente terapéutico, métodos de uso y métodos de fabricación
EP2968118B1 (de) 2013-03-15 2022-02-09 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur verwendung
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
WO2014168841A1 (en) * 2013-04-08 2014-10-16 Irhythm Technologies, Inc Skin abrader
US9750533B2 (en) * 2013-04-12 2017-09-05 L'oreal Exfoliating head for a personal care appliance
KR20220010055A (ko) 2013-08-09 2022-01-25 사이트렐리스 바이오시스템즈, 인크. 비-열적 조직 절제를 사용한 피부 치료를 위한 방법 및 기구
US10953143B2 (en) 2013-12-19 2021-03-23 Cytrellis Biosystems, Inc. Methods and devices for manipulating subdermal fat
WO2015177976A1 (ja) * 2014-05-20 2015-11-26 凸版印刷株式会社 針状体の製造方法、及び針状体
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
US20160120434A1 (en) 2014-10-31 2016-05-05 Irhythm Technologies, Inc. Wireless physiological monitoring device and systems
WO2016077759A1 (en) 2014-11-14 2016-05-19 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
EP3237055B1 (de) 2014-12-23 2020-08-12 Edge Systems LLC Vorrichtungen und verfahren zur behandlung der haut unter verwendung eines rollerballs oder eines abführenden elements
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
WO2016123665A1 (en) 2015-02-02 2016-08-11 Vaxxas Pty Limited Microprojection array applicator and method
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
KR20240014104A (ko) 2015-07-08 2024-01-31 하이드라페이셜 엘엘씨 모발 성장을 촉진하기 위한 디바이스, 시스템 및 방법
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
WO2017172920A1 (en) 2016-03-29 2017-10-05 Cytrellis Biosystems, Inc. Devices and methods for cosmetic skin resurfacing
BR112019005312A2 (pt) * 2016-09-21 2019-07-16 Cytrellis Biosystems Inc dispositivos e métodos para a recomposição cosmética da pele
CN108290430B (zh) * 2016-10-24 2020-03-20 株式会社秀峰 印刷用橡皮布的活化装置以及使用了印刷用橡皮布的印刷方法
EP3338853A1 (de) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medikamentenverabreichungsvorrichtung
CN106581851B (zh) * 2017-01-09 2020-03-20 上海理工大学 一种具有磁热效应的药物控释透皮微针系统及制备方法和应用
EP4306803A3 (de) 2017-03-31 2024-04-10 Vaxxas Pty Limited Vorrichtung und verfahren zur beschichtung von oberflächen
EP3639010A4 (de) 2017-06-13 2021-03-17 Vaxxas Pty Limited Qualitätskontrolle von substratbeschichtungen
EP4218893A1 (de) 2017-08-04 2023-08-02 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
WO2020044853A1 (ja) * 2018-08-28 2020-03-05 Ｎｉｓｓｈａ株式会社 肌改質シート
EP3856761A1 (de) 2018-09-24 2021-08-04 Krystal Biotech, Inc. Zusammensetzungen und verfahren zur behandlung des netherton-syndroms
US11813056B2 (en) * 2019-07-31 2023-11-14 Washington University Materials and methods for implementing immunoassay on microneedle patch for detection and quantification of bioanalytes in interstitial fluid
GR20190100445A (el) * 2019-10-09 2021-05-19 Ανδρεας Κωνσταντινου Λαγκης Κνηστρο ενισχυσης ανοσοποιητικου
CN110833654A (zh) * 2019-11-20 2020-02-25 吉林省申吉医疗器械科技有限公司 一种无痛透皮美容微针贴及其制备方法
US11083371B1 (en) 2020-02-12 2021-08-10 Irhythm Technologies, Inc. Methods and systems for processing data via an executable file on a monitor to reduce the dimensionality of the data and encrypting the data being transmitted over the wireless network
CN115697209A (zh) * 2020-06-11 2023-02-03 新加坡科技研究局 皮肤微生物采样器及相关方法
CN116322497A (zh) 2020-08-06 2023-06-23 意锐瑟科技公司 粘性生理监测装置
WO2022032118A1 (en) 2020-08-06 2022-02-10 Irhythm Technologies, Inc. Electrical components for physiological monitoring device
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
USD1024328S1 (en) 2023-02-14 2024-04-23 Pro Cell Therapies, LLC Micro-needle tip assembly

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4538612A (en) * 1983-08-29 1985-09-03 Ndm Corporation Skin preparation method and product
JPS62270144A (ja) * 1986-03-03 1987-11-24 久光製薬株式会社 経皮投薬用皮膚損傷装置
US5120542A (en) * 1986-03-31 1992-06-09 Imperial Chemical Industries Plc Pesticide compositions and method
AU614092B2 (en) 1987-09-11 1991-08-22 Paul Max Grinwald Improved method and apparatus for enhanced drug permeation of skin
CA2008262A1 (en) 1989-01-30 1990-07-30 John A. Gilly Clinical applicator
US5091379A (en) * 1989-08-31 1992-02-25 Du Pont Merck Pharmaceutical Company Topical antinflammatory compositions with minimal systemic absorption
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
SU1724181A1 (ru) 1990-03-22 1992-04-07 Ивано-Франковский Государственный Медицинский Институт Устройство дл камерно-скарификационного тестировани кожи
US5383848A (en) * 1990-04-12 1995-01-24 Gensia, Inc. Iontophoretic administration of drugs
TW279133B (de) 1990-12-13 1996-06-21 Elan Med Tech
US5273528A (en) 1992-07-10 1993-12-28 Skeen Mikell L Livestock inoculator
DE4307869C2 (de) 1993-03-12 1996-04-04 Microparts Gmbh Mikrostrukturkörper und Verfahren zu deren Herstellung
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5660680A (en) 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
CA2149943C (en) 1994-05-23 1999-07-13 Kwang Kyun Jang Skin perforating device for transdermal medication
US5591139A (en) 1994-06-06 1997-01-07 The Regents Of The University Of California IC-processed microneedles
WO1996007369A1 (en) 1994-09-05 1996-03-14 Cyanamid Websters Pty. Limited Scratch vaccine applicator and/or method of applying a vaccine
US5895369A (en) 1994-09-30 1999-04-20 Becton Dickinson And Company Iontophoresis patch/controller interconnection using a conductive elastomer to provide noise-free electrical contact between patch and controller
WO1996037256A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
US5685515A (en) 1995-06-06 1997-11-11 Kasa, Inc. Mirror tilt mechanism
US5958589A (en) 1995-07-07 1999-09-28 The United States Of America As Represented By The Secretary Of Agriculture Starch-based microcellular foams
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
GB9520209D0 (en) 1995-09-25 1995-12-06 Cawley R Skin cleaning apparatus
CA2253549C (en) 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US5919364A (en) 1996-06-24 1999-07-06 Regents Of The University Of California Microfabricated filter and shell constructed with a permeable membrane
JP2002515786A (ja) * 1996-06-28 2002-05-28 ソントラ メディカル，エル．ピー． 経皮輸送の超音波増強
US6183434B1 (en) * 1996-07-03 2001-02-06 Spectrx, Inc. Multiple mechanical microporation of skin or mucosa
US5910306A (en) 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
WO1998032526A1 (en) 1997-01-24 1998-07-30 The Regents Of The University Of California Apparatus and method for planar laminar mixing
US5873850A (en) 1997-05-29 1999-02-23 Becton Dickinson And Company Locking and disfiguring mechanism for an iontophoretic system
US5928207A (en) 1997-06-30 1999-07-27 The Regents Of The University Of California Microneedle with isotropically etched tip, and method of fabricating such a device
WO1999003521A1 (en) * 1997-07-14 1999-01-28 Novo Nordisk A/S Injection member
US5899876A (en) 1997-08-27 1999-05-04 Becton, Dickinson And Company Multiple site drug delivery system
US5882677A (en) 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
US5931794A (en) 1997-10-21 1999-08-03 Pitesky; Isadore Allergy testing apparatus
WO1999029364A1 (en) * 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
AU3311599A (en) 1998-02-25 1999-09-15 Iomai Corporation Use of skin penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response induced by adp-ribosylating exotoxin
US5970998A (en) 1998-02-27 1999-10-26 The Regents Of The University Of California Microfabricated cantilever ratchet valve, and method for using same
US6173202B1 (en) 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6106751A (en) 1998-03-18 2000-08-22 The Regents Of The University Of California Method for fabricating needles via conformal deposition in two-piece molds
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6312612B1 (en) 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6211243B1 (en) * 1999-09-22 2001-04-03 B. Ron Johnson Methods for treating cold sores with anti-infective compositions
US6494865B1 (en) 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate

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US20060264893A1 (en) 2006-11-23
US20090036826A1 (en) 2009-02-05
US6835184B1 (en) 2004-12-28
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CA2316534A1 (en) 2001-03-24
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