DE60017888D1 - Dinatrium-salze, monohydrate und ethanol-solvate - Google Patents
Dinatrium-salze, monohydrate und ethanol-solvateInfo
- Publication number
- DE60017888D1 DE60017888D1 DE60017888T DE60017888T DE60017888D1 DE 60017888 D1 DE60017888 D1 DE 60017888D1 DE 60017888 T DE60017888 T DE 60017888T DE 60017888 T DE60017888 T DE 60017888T DE 60017888 D1 DE60017888 D1 DE 60017888D1
- Authority
- DE
- Germany
- Prior art keywords
- ethanol solvate
- delivery agents
- disodium salt
- ethanol
- monohydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12775499P | 1999-04-05 | 1999-04-05 | |
| US127754P | 1999-04-05 | ||
| US18614300P | 2000-03-01 | 2000-03-01 | |
| US18614200P | 2000-03-01 | 2000-03-01 | |
| US186143P | 2000-03-01 | ||
| US186142P | 2000-03-01 | ||
| US19128600P | 2000-03-21 | 2000-03-21 | |
| US191286P | 2000-03-21 | ||
| PCT/US2000/009390 WO2000059863A1 (en) | 1999-04-05 | 2000-04-05 | Disodium salts, monohydrates, and ethanol solvates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60017888D1 true DE60017888D1 (de) | 2005-03-10 |
| DE60017888T2 DE60017888T2 (de) | 2006-01-19 |
Family
ID=27494697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60017888T Expired - Lifetime DE60017888T2 (de) | 1999-04-05 | 2000-04-05 | Dinatrium-salze, monohydrate und ethanol-solvate |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US20020065255A1 (de) |
| EP (1) | EP1175390B1 (de) |
| JP (2) | JP4588221B2 (de) |
| AT (1) | ATE288415T1 (de) |
| AU (1) | AU4216700A (de) |
| CA (1) | CA2369591C (de) |
| DE (1) | DE60017888T2 (de) |
| ES (1) | ES2235854T3 (de) |
| HK (1) | HK1045680A1 (de) |
| IL (4) | IL145546A0 (de) |
| NZ (1) | NZ534409A (de) |
| WO (1) | WO2000059863A1 (de) |
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-
2000
- 2000-04-05 WO PCT/US2000/009390 patent/WO2000059863A1/en active Application Filing
- 2000-04-05 AU AU42167/00A patent/AU4216700A/en not_active Abandoned
- 2000-04-05 NZ NZ534409A patent/NZ534409A/xx not_active IP Right Cessation
- 2000-04-05 EP EP00921909A patent/EP1175390B1/de not_active Expired - Lifetime
- 2000-04-05 CA CA2369591A patent/CA2369591C/en not_active Expired - Lifetime
- 2000-04-05 AT AT00921909T patent/ATE288415T1/de active
- 2000-04-05 IL IL14554600A patent/IL145546A0/xx active IP Right Grant
- 2000-04-05 JP JP2000609376A patent/JP4588221B2/ja not_active Expired - Lifetime
- 2000-04-05 DE DE60017888T patent/DE60017888T2/de not_active Expired - Lifetime
- 2000-04-05 ES ES00921909T patent/ES2235854T3/es not_active Expired - Lifetime
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2001
- 2001-09-21 IL IL145546A patent/IL145546A/en not_active IP Right Cessation
- 2001-09-24 US US09/962,794 patent/US20020065255A1/en not_active Abandoned
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- 2008-04-29 US US12/111,750 patent/US7659311B2/en not_active Expired - Fee Related
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- 2009-12-18 US US12/642,508 patent/US8003697B2/en not_active Expired - Fee Related
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2011
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2235854T3 (es) | 2005-07-16 |
| IL166158A0 (en) | 2006-01-15 |
| DE60017888T2 (de) | 2006-01-19 |
| US7659311B2 (en) | 2010-02-09 |
| US20080269134A1 (en) | 2008-10-30 |
| EP1175390A1 (de) | 2002-01-30 |
| HK1045680A1 (en) | 2002-12-06 |
| US20020065255A1 (en) | 2002-05-30 |
| JP4642435B2 (ja) | 2011-03-02 |
| JP2005068161A (ja) | 2005-03-17 |
| EP1175390A4 (de) | 2002-09-04 |
| IL180118A (en) | 2010-12-30 |
| JP2002541132A (ja) | 2002-12-03 |
| ATE288415T1 (de) | 2005-02-15 |
| IL166158A (en) | 2010-12-30 |
| US20040106825A1 (en) | 2004-06-03 |
| US8658695B2 (en) | 2014-02-25 |
| US20110251125A1 (en) | 2011-10-13 |
| IL145546A (en) | 2007-10-31 |
| JP4588221B2 (ja) | 2010-11-24 |
| US20120264834A1 (en) | 2012-10-18 |
| CA2369591C (en) | 2011-06-14 |
| US8207227B2 (en) | 2012-06-26 |
| NZ534409A (en) | 2006-03-31 |
| US8003697B2 (en) | 2011-08-23 |
| IL145546A0 (en) | 2002-06-30 |
| EP1175390B1 (de) | 2005-02-02 |
| US20100099621A1 (en) | 2010-04-22 |
| AU4216700A (en) | 2000-10-23 |
| WO2000059863A1 (en) | 2000-10-12 |
| CA2369591A1 (en) | 2000-10-12 |
| US7384982B2 (en) | 2008-06-10 |
| IL180118A0 (en) | 2007-06-03 |
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Owner name: EMISPHERE TECHNOLOGIES, INC., CEDAR KNOLLS, N., US |