DE59106348D1 - Herstellungsverfahren für schnellzerfallende folienförmige Darreichungsformen. - Google Patents

Herstellungsverfahren für schnellzerfallende folienförmige Darreichungsformen.

Info

Publication number
DE59106348D1
DE59106348D1 DE59106348T DE59106348T DE59106348D1 DE 59106348 D1 DE59106348 D1 DE 59106348D1 DE 59106348 T DE59106348 T DE 59106348T DE 59106348 T DE59106348 T DE 59106348T DE 59106348 D1 DE59106348 D1 DE 59106348D1
Authority
DE
Germany
Prior art keywords
weight
mixture
manufacturing process
dosage forms
rapidly disintegrating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59106348T
Other languages
English (en)
Inventor
Michael Dr Horstmann
Wolfgang Laux
Stefan Hungerbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of DE59106348D1 publication Critical patent/DE59106348D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/343Products for covering, coating, finishing, decorating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/06COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing beet sugar or cane sugar if specifically mentioned or containing other carbohydrates, e.g. starches, gums, alcohol sugar, polysaccharides, dextrin or containing high or low amount of carbohydrate
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2210/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing inorganic compounds or water in high or low amount
DE59106348T 1990-06-07 1991-06-04 Herstellungsverfahren für schnellzerfallende folienförmige Darreichungsformen. Expired - Lifetime DE59106348D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4018247A DE4018247A1 (de) 1990-06-07 1990-06-07 Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen

Publications (1)

Publication Number Publication Date
DE59106348D1 true DE59106348D1 (de) 1995-10-05

Family

ID=6407961

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4018247A Granted DE4018247A1 (de) 1990-06-07 1990-06-07 Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen
DE59106348T Expired - Lifetime DE59106348D1 (de) 1990-06-07 1991-06-04 Herstellungsverfahren für schnellzerfallende folienförmige Darreichungsformen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4018247A Granted DE4018247A1 (de) 1990-06-07 1990-06-07 Herstellungsverfahren fuer schnellzerfallende folienfoermige darreichungsformen

Country Status (9)

Country Link
US (1) US5629003A (de)
EP (1) EP0460588B1 (de)
JP (1) JP2559301B2 (de)
AT (1) ATE127016T1 (de)
CA (1) CA2044043C (de)
DE (2) DE4018247A1 (de)
DK (1) DK0460588T3 (de)
ES (1) ES2078994T3 (de)
GR (1) GR3018233T3 (de)

Families Citing this family (170)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4416927C1 (de) * 1994-05-13 1995-08-31 Lohmann Therapie Syst Lts Vorrichtung zur Abgabe von Wirkstoffen aus Haftschmelzklebern, Verfahren zu ihrer Herstellung und ihre Verwendung
DE4419824A1 (de) * 1994-06-07 1995-12-14 Lohmann Therapie Syst Lts Volumen-expandierbares, als Wirkstoffträger insbesondere zur oralen Anwendung geeignete flächige Anwendungsform
US5958450A (en) * 1994-12-05 1999-09-28 Phillip Peatey & Gunter Pauli Method of drug delivery and coated oral dosage forms for use in the method
DE19500977C2 (de) * 1995-01-14 1999-01-07 Lohmann Therapie Syst Lts Feste Arzneimittelform mit in polymerem Material verteiltem Wirkstoff
DE19503336C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Wirkstoffen an Wunden, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19508029C2 (de) * 1995-03-07 1997-10-09 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation von ophthalmischen Arzneistoffen und Verfahren zur Herstellung derselben
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
DE19652257A1 (de) * 1996-12-16 1998-06-18 Lohmann Therapie Syst Lts Einzeln dosierte, bei Kontakt mit Flüssigkeit schnell zerfallende, wirkstoff- und insbesondere aromastoffhaltige, folienförmige Darreichnungsform
US6096328A (en) * 1997-06-06 2000-08-01 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
DE19745208A1 (de) * 1997-10-13 1999-04-15 Labtec Gmbh Mundfilm
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
WO1999055736A2 (en) 1998-04-27 1999-11-04 Larex, Inc. Derivatives of arabinogalactan and compositions including the same
US20030211136A1 (en) * 1998-09-25 2003-11-13 Neema Kulkarni Fast dissolving orally consumable films containing a sweetener
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
DE19856101A1 (de) * 1998-12-04 2000-06-08 Labtec Gmbh Mundhöhlen-Matrixpflaster
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
GB9901819D0 (en) * 1999-01-27 1999-03-17 Scherer Corp R P Pharmaceutical compositions
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6800329B2 (en) * 1999-02-12 2004-10-05 Lts Lohmann Therapie-Systeme Ag Method for producing film-type dosage
HUP0201620A3 (en) 1999-07-02 2003-02-28 Procter & Gamble Delivery system for oral care compositions comprising organosiloxane resins using a removable backing strip
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
AU781878B2 (en) * 1999-12-09 2005-06-16 Derma Sciences, Inc. Use of honey in medical dressings
US7067116B1 (en) 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
IT1318597B1 (it) * 2000-06-23 2003-08-27 A C R Applied Coating Res S A Uso di un amido ad alto contenuto di amilosio acetilato epregelatinizzato.
DE10034491A1 (de) * 2000-07-15 2002-01-24 Scs Skin Care Systems Gmbh Folien-Dermatika
TR200300731T2 (tr) 2000-11-28 2004-08-23 Fmc Corporation Yenebilir PGA kaplama bileşimi
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
CA2449415A1 (en) * 2001-04-20 2002-10-31 Lavipharm Laboratories Inc. Intraoral delivery of nicotine for smoking cessation
CN1462194B (zh) * 2001-04-24 2013-04-24 琳得科株式会社 口服给药制剂及口服给药制剂保持体
US8268333B2 (en) 2001-04-24 2012-09-18 Lintec Corporation Orally administered agent and an orally administered agent/supporting substrate complex
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
WO2003030882A1 (en) * 2001-10-12 2003-04-17 Kosmos Pharma Thin film with non-self-aggregating uniform heterogeneity, process for their production and drug delivery systems made thereform
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
EP1317916B1 (de) * 2001-11-16 2010-10-27 Akzo Nobel Chemicals International B.V. Filme enthaltend modifizierte Stärke
US8529807B2 (en) * 2002-01-17 2013-09-10 Lts Lohmann Therapie-Systeme Ag Method for neutralizing or recycling carrier materials for film-like coatings
WO2003061635A2 (en) 2002-01-25 2003-07-31 Lts Lohmann Therapie-Systeme Ag Method and device for producing products in web form
US20030224090A1 (en) * 2002-02-11 2003-12-04 Edizone, Lc Snacks of orally soluble edible films
DE10207394B4 (de) * 2002-02-21 2007-03-29 Lts Lohmann Therapie-Systeme Ag Geschmacksmaskierte oblatenförmige Arzneizubereitung
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
FR2840221B1 (fr) * 2002-06-04 2006-01-13 Backert Marie Elisabeth Cuine Film polymerique contenant des "actifs" destines a etre liberes dans un liquide
US20030228264A1 (en) * 2002-06-06 2003-12-11 Perna Salvatore F. Dissolvable teeth whitening apparatus
EP1542903B1 (de) * 2002-07-22 2015-05-20 MonoSolRX, LLC Verpackung und verabreichung einer schnell auflösenden dosierform
US7241411B2 (en) * 2002-08-23 2007-07-10 Acupac Packaging, Inc. Thin film strips
US6824829B2 (en) * 2002-08-23 2004-11-30 Acupac Packaging, Inc. Process for manufacturing thin film strips
DE10239101B4 (de) * 2002-08-27 2005-06-16 Scs Skin Care Systems Gmbh Pflaster zur Verabreichung von Deodorantien
GB2392446A (en) * 2002-09-02 2004-03-03 Reckitt Benckiser Nv Resin comprising water-soluble polymer and water-soluble filler
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US6916463B2 (en) * 2002-09-24 2005-07-12 The Procter & Gamble Company Oral products having an aesthetic layer
EP1571915B1 (de) * 2002-10-30 2010-12-15 MacQuarrie, Reg Essbare, sich auflösende gelatinestreifen
US20060205629A1 (en) 2002-10-30 2006-09-14 Reg Macquarrie Edible dissolving gelatin strips
US8999372B2 (en) * 2002-11-14 2015-04-07 Cure Pharmaceutical Corporation Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use
US20040191302A1 (en) * 2003-03-28 2004-09-30 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US9561182B2 (en) * 2003-08-22 2017-02-07 Cure Pharmaceutical Corporation Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals
US20040131662A1 (en) 2003-11-12 2004-07-08 Davidson Robert S. Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films
US20040111275A1 (en) * 2002-11-15 2004-06-10 Kroll David B. Methods for marketing and generating revenue from edible thin films
US20040096569A1 (en) * 2002-11-15 2004-05-20 Barkalow David G. Edible film products and methods of making same
EP1568346B1 (de) 2002-12-02 2016-06-22 Kyukyu Pharmaceutical Co., Ltd. Verfahren zur herstellung eines essbaren oral verabreichten mittels in form eines laminatfilms und kompressionsverbindungsgerät
WO2004066986A1 (en) * 2003-01-30 2004-08-12 Monosolrx Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20040156794A1 (en) * 2003-02-11 2004-08-12 Barkalow David G. Bioerodible and bioadhesive confectionery products and methods of making same
US20040180110A1 (en) 2003-03-14 2004-09-16 Atul Mistry Chewing gum and confectionery compositions containing an endothermic agent
JP2006515332A (ja) * 2003-03-26 2006-05-25 ザ プロクター アンド ギャンブル カンパニー セルロースフィルム形成ポリマーを有する急速溶解性食用フィルム組成物
EP1605908A2 (de) * 2003-03-26 2005-12-21 The Procter & Gamble Company Schnell auflösende essbare filmzusammensetzungen mit verbesserter filmstärke und stabilität
BRPI0409357B8 (pt) * 2003-04-14 2021-05-25 Dupont Nutrition Usa Inc película de gel termorreversível homogênea, processo para fabricar as películas de gel, cápsulas moles, processo para fabricar as cápsulas moles, e, forma sólida
AU2004233744A1 (en) * 2003-05-02 2004-11-11 Warner-Lambert Company Llc Fast dissolving orally consumable films containing a modified starch for improved heat and moisture resistance
CN102670568A (zh) 2003-05-28 2012-09-19 莫诺索尔克斯有限公司 基于聚氧乙烯的薄膜及由其制造的药物传递系统
US20040241294A1 (en) * 2003-05-31 2004-12-02 Barabolak Roman M. Edible films including aspartame and methods of making same
JP4427981B2 (ja) * 2003-06-26 2010-03-10 救急薬品工業株式会社 フィルム状口腔内投与剤の打ち抜き成型方法
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
DE10338544B4 (de) * 2003-08-19 2017-08-31 Janssen Pharmaceutica N.V. Buccale Formulierungen des Galanthamins und deren Anwendungen
US7666396B2 (en) * 2003-09-11 2010-02-23 Kimberly-Clark Worldwide, Inc. Single-use moisturizing product
DK1695094T3 (da) * 2003-10-24 2013-09-16 Adhesives Res Inc Disintegrerende film til diagnostiske indretninger
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN104397869B (zh) 2003-11-07 2016-06-08 美国无烟烟草有限责任公司 烟草组合物
DE10354894A1 (de) * 2003-11-24 2005-07-07 Hf Arzneimittelforschung Gmbh Orale Formulierungen des Desoxypeganins und deren Anwendungen
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
DE102004002951A1 (de) * 2004-01-21 2005-08-11 Wella Ag Verfahren zur Herstellung haarfestigender Produkte in Folienform
US20050222539A1 (en) * 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
US20050226906A1 (en) * 2004-04-08 2005-10-13 Micro Nutrient, Llc Nutrient system for individualized responsive dosing regimens
US7850987B2 (en) * 2004-04-08 2010-12-14 Micronutrient, Llc Nutrient composition(s) and system(s) for individualized, responsive dosing regimens
US7785619B2 (en) * 2004-04-08 2010-08-31 Micro Nutrient, Llc Pharmanutrient composition(s) and system(s) for individualized, responsive dosing regimens
EP1586243B1 (de) 2004-04-15 2007-08-08 MacQuarrie, Reg Essbare Filmüberzugzusammensetzung für Lebensmittelherstellung
US7972589B2 (en) * 2004-05-17 2011-07-05 Akzo Nobel N.V. Hair fixative film
US9267167B2 (en) 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
EP1802698B1 (de) * 2004-10-18 2012-04-25 Plantic Technologies Limited Barrierefolie
FR2880262B1 (fr) * 2005-01-03 2013-11-08 Oreal Article cosmetique ou dermatologique comportant un support soluble dans l'eau
US20070110792A9 (en) * 2005-01-03 2007-05-17 L'oreal Cosmetic or dermatological article comprising a medium that is soluble in water
DE102005005633A1 (de) * 2005-02-08 2006-08-10 Wacker Polymer Systems Gmbh & Co. Kg Lösungmittelfrei herstellbare Dispersion enthaltend einen 1:1 oder 2:1-Cyclodextrin-Riechstoff-Komplex
US20090232911A1 (en) * 2005-03-25 2009-09-17 Yoichi Kato Use of sericin for improving feeling in use of denture
WO2006119286A1 (en) * 2005-05-03 2006-11-09 Innozen, Inc. Edible film for transmucosal delivery of nutritional supplements
WO2006127879A1 (en) * 2005-05-26 2006-11-30 Duramed Pharmaceuticals, Inc. Flexible solid dosage forms and methods of making and using the same
DE102005033943A1 (de) * 2005-07-20 2007-02-22 Hexal Ag Nicht-ausspuckbarer, oraler, schnell-zerfallender Film für ein Neuroleptikum
DE102005058158A1 (de) * 2005-12-05 2007-06-06 Henkel Kgaa Folie zum Färben keratinischer Fasern
US20070148248A1 (en) 2005-12-22 2007-06-28 Banner Pharmacaps, Inc. Gastric reflux resistant dosage forms
US20070190157A1 (en) * 2006-01-20 2007-08-16 Monosoirx, Llc. Film lined packaging and method of making same
CN101404990B (zh) * 2006-03-16 2012-04-25 诺瓦提斯公司 含有味道被掩蔽的活性剂的固体剂型
EP1897543A1 (de) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine-Waffel zur Substitutionstherapie
AU2007297697A1 (en) * 2006-09-20 2008-03-27 Monosol Rx Llc Edible water-soluble film containing a foam reducing flavoring agent
WO2008042331A2 (en) * 2006-09-29 2008-04-10 Monosol Rx Llc Film embedded packaging and method of making same
CN105168186A (zh) 2006-10-02 2015-12-23 Apr应用制药研究股份公司 非粘膜粘着性膜剂型
CA2675356A1 (en) * 2007-01-12 2008-07-24 Monosol Rx, Llc High dose film compositions and methods of preparation
FR2912915B1 (fr) * 2007-02-28 2012-11-16 Pf Medicament Film a desintegration rapide pour l'administration buccale de substances actives.
US20080292683A1 (en) * 2007-05-24 2008-11-27 Monosolrx, Llc. Film shreds and delivery system incorporating same
FR2916635B1 (fr) * 2007-05-30 2009-08-07 Backert Marie Elisabeth Cuine Formulations solides pour l'administration, par voie parente parenterale, d'acti(s),sous forme d'un film destine a etre dissout et/ou disperse dans un produit liquide
US9125836B2 (en) 2007-06-07 2015-09-08 Sato Pharmaceutical Co., Ltd. Film preparation with rapidly dissolving property and flexibility
US8298583B2 (en) 2007-10-19 2012-10-30 Monosol Rx, Llc Film delivery system for tetrahydrolipstatin
US20090253754A1 (en) * 2007-12-04 2009-10-08 Francesca Selmin Fast dissolving films and coatings for controlled release of flavors, active pharmaceutical ingredients, food substances, and nicotine
DE102008023345B4 (de) 2008-05-13 2014-12-04 Lts Lohmann Therapie-Systeme Ag Filmförmige Zubereitung mit öligen Substanzen zur oralen Verabreichung
US9265779B2 (en) 2008-05-13 2016-02-23 Lts Lohmann Therapie-Systeme Ag Method of using a film-shaped preparation comprising oily substances for oral administration
US20100040727A1 (en) * 2008-08-18 2010-02-18 Monosol Rx, Llc Method for Improving Uniformity of Content in Edible Film Manufacturing
US8282954B2 (en) * 2008-12-15 2012-10-09 Monosol Rx, Llc Method for manufacturing edible film
US20100285130A1 (en) * 2009-05-06 2010-11-11 Monosol Rx, Llc Coating of complexed actives in film formulations
US20100297232A1 (en) * 2009-05-19 2010-11-25 Monosol Rx, Llc Ondansetron film compositions
CN105411869A (zh) * 2009-05-26 2016-03-23 高露洁-棕榄公司 洁齿剂组合物
PT2442650E (pt) 2009-06-12 2015-12-18 Cynapsus Therapeutics Inc Apomorfina sublingual
US8475832B2 (en) * 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
CA2783877A1 (en) * 2009-12-10 2011-06-16 A. Mark Schobel Ph sensitive compounds in taste masking within oral thin film strips
JP2013523634A (ja) * 2010-03-26 2013-06-17 ダウ グローバル テクノロジーズ エルエルシー 溶融押出フィルム
EP2579844B1 (de) 2010-06-10 2016-02-24 Midatech Ltd. Systeme zur freisetzung von nanopartikeln
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US10238684B2 (en) 2010-11-18 2019-03-26 Foundational Biosystems, Llc Micro- and nano-quantity sleep enhancing nutrient composition and method of enhancing central nervous system protein clearance using same
DK2651357T3 (da) 2010-12-16 2020-06-02 Sunovion Pharmaceuticals Inc Sublinguale film
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
CA2878680C (en) 2012-07-23 2019-09-17 Crayola, Llc Dissolvable films and methods of using the same
CN104736133B (zh) 2012-10-17 2020-07-10 宝洁公司 用于递送口腔护理活性物质的条带以及施用口腔护理活性物质的方法
US20140275194A1 (en) 2013-03-15 2014-09-18 Monosol Rx, Llc Films and drug delivery systems for rizatriptan
WO2014145699A1 (en) 2013-03-15 2014-09-18 New Jersey Institute Of Technology System and method for fabrication of uniform polymer films containing nano and micro particles via continuous drying process
US9303918B2 (en) 2013-03-15 2016-04-05 Monosol Rx, Llc Process for drying a wet film with control of loss on drying
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
JP2015154716A (ja) * 2014-02-19 2015-08-27 日本合成化学工業株式会社 食用フィルム
CN106535898A (zh) 2014-04-04 2017-03-22 细胞内治疗公司 有机化合物
WO2015200149A1 (en) 2014-06-23 2015-12-30 Banner Life Sciences Llc All natural enteric soft capsules comprising active ingredients
EP3283173A1 (de) 2015-04-14 2018-02-21 The Procter and Gamble Company Feste konditionierungszusammensetzung
JP7211706B2 (ja) 2015-04-21 2023-01-24 サノヴィオン ファーマシュティカルズ インコーポレーテッド 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法
BR112018015283B1 (pt) 2016-01-26 2023-09-26 Intra-Cellular Therapies, Inc Compostos orgânicos, composição farmacêutica compreendendo os ditos compostos e uso dos mesmos para o tratamento ou profilaxia de um distúrbio do sistema nervoso central
EP3407889B1 (de) 2016-03-25 2021-05-19 Intra-Cellular Therapies, Inc. Organische verbindungen und deren verwendung zur behandlung oder prävention von erkrankungen des zentralen nervensystems
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
BR112018072539A2 (pt) 2016-05-05 2019-03-26 Aquestive Therapeutics, Inc. composições de epinefrina de administração aumentada
US10329519B2 (en) 2016-10-19 2019-06-25 The Procter & Gamble Company Consumer product composition comprising a polyethyleneglycol carrier, silicone conditioner, and particulate spacer material
US10906906B2 (en) 2016-12-29 2021-02-02 Intra-Cellular Therapies, Inc. Organic compounds
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
CN116327770A (zh) 2017-03-24 2023-06-27 细胞内治疗公司 新组合物和方法
US10238600B2 (en) 2017-04-13 2019-03-26 Richard C. Fuisz Package, system and methods for custody and control of drugs, and method and composition for making an oral soluble film, containing at least one active agent
US9901545B1 (en) 2017-04-13 2018-02-27 Richard C. Fuisz Method and composition for making an oral soluble film, containing at least one active agent
KR20210052471A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
JP7457000B2 (ja) 2018-08-31 2024-03-27 イントラ-セルラー・セラピーズ・インコーポレイテッド 新規方法
US11173114B1 (en) 2020-07-10 2021-11-16 Nova Thin Film Pharmaceuticals Llc Method and system for manufacturing and oral soluble films and oral soluble films made by thereby

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US352466A (en) * 1886-11-09 Geoege cheistopheb huttemeyee
BE637363A (de) *
US2852433A (en) * 1956-03-07 1958-09-16 Eastman Kodak Co Method of making enteric medicament compositions
DE2028224A1 (de) * 1969-06-10 1970-12-17 Solco Basel AG, Basel (Schweiz)j Oral anwendbare Arzneimittelform
IN142428B (de) * 1974-07-05 1977-07-09 Schering Ag
US4136145A (en) * 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
AU514195B2 (en) * 1975-12-15 1981-01-29 F. Hoffmann-La Roche & Co. Dosage form
ZA767136B (en) * 1975-12-15 1977-10-26 Hoffmann La Roche Novel dosage form
GB2009597B (en) * 1977-12-10 1982-06-23 Beecham Group Ltd Antacid compositions
US4683256A (en) * 1980-11-06 1987-07-28 Colorcon, Inc. Dry edible film coating composition, method and coating form
JPS6185315A (ja) * 1984-10-04 1986-04-30 Teikoku Seiyaku Kk シ−ト状製剤
AU6541786A (en) * 1985-10-09 1987-05-05 Desitin Arzneimittel Gmbh Process for producing an administration or dosage form of drugs, reagents or other active ingredients
DE3630603A1 (de) * 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung
US4906488A (en) * 1987-05-01 1990-03-06 Arcade, Inc. Modification of permeant
DE3744009A1 (de) * 1987-12-24 1989-07-06 Fresenius Ag Geschmacksneutrale, eine oder mehrere aminosaeuren enthaltende pharmazeutische zubereitung
US5077053A (en) * 1990-02-12 1991-12-31 Warner-Lambert Company Zein as a moisture barrier for sugarless edible compositions and method for preparing same

Also Published As

Publication number Publication date
CA2044043C (en) 1998-04-28
ATE127016T1 (de) 1995-09-15
ES2078994T3 (es) 1996-01-01
JP2559301B2 (ja) 1996-12-04
EP0460588A1 (de) 1991-12-11
GR3018233T3 (en) 1996-02-29
US5629003A (en) 1997-05-13
JPH07100186A (ja) 1995-04-18
DK0460588T3 (da) 1995-08-30
EP0460588B1 (de) 1995-08-30
DE4018247C2 (de) 1992-05-14
CA2044043A1 (en) 1991-12-08
DE4018247A1 (de) 1991-12-12

Similar Documents

Publication Publication Date Title
DE59106348D1 (de) Herstellungsverfahren für schnellzerfallende folienförmige Darreichungsformen.
DE3854148D1 (de) Fluorcytidinderivate, deren Herstellung und Arzneimittel, die diese Derivate enthalten.
ES472838A1 (es) Procedimientos para la obtencion de derivados de 3,4,5-tri- hidropiperidina.
ATE56869T1 (de) Lang wirksame cefaclor-formulierung und deren herstellung.
ATE220321T1 (de) Feste flupirtin enthaltende orale darreichungsformen mit kontrollierter wirkstoffabgabe
DE3783923D1 (de) Einen wirkstoff und ein in wasser quellendes polymer enthaltendes arzneimittel.
MX9305143A (es) Composiciones nutritivas o medicamentos a base de quitosana, para la administracion de los rumiantes y procedimiento para su preparacion.
RU93043304A (ru) Кормовые или медикаментозные композиции для жвачных животных и способ их получения
CA2078869A1 (en) Pharmaceutical compositions containing ipriflavone, process for the preparation thereof and relative therapeutic use
ES8102096A1 (es) Procedimiento para la obtencion de derivados de 3,4,5-trihi-droxipiperidina
ATE3033T1 (de) Derivate des 2-hydroxymethyl-3,4,5-trihydroxypiperidins, ihre herstellung und sie enthaltende arzneimittel.
ATE24111T1 (de) Mischung mit gehalt an einem zentral-analgetikum und an vitamine b12 oder einem seiner analoge als wirkstoffe.
ATE35620T1 (de) Pharmazeutische zubereitung mit retardwirkung.
ATE15331T1 (de) Verfahren fuer die orale verabreichung von substanzen in der form von liposomen, und ihre pharmazeutischen zusammensetzungen.
DE59107240D1 (de) Emulgatorfreie Emulsionspolymere in pharmazeutischen Zubereitungen mit verzögerter Wirkstofffreigabe und ihre Herstellung
FR2661611B1 (fr) Nouvelles compositions pharmaceutiques a base de polycarbophil et leur procede d'obtention.
DE3483285D1 (de) Etofenamat-zubereitung.
EP0132772A3 (en) Fr-900216 substance obtainable by cultivating atcc 20577 for use as an active therapeutic substance and pharmaceutical antitumor composition comprising fr-900216 substance
TH14341EX (th) สารอาหารหรือสูตรผสมยาสำหรับการให้สู่ร่างกายของสัตว์เคี้ยวเอื้อง
KR900003198A (ko) 신규 글루탐산 유도체, 그의 염, 그의 제조방법, 이들의 의약품으로서의 용도 및 이들을 함유한 조성물
ATE1011T1 (de) 5-fluoruracil-derivate, deren herstellung und ihre pharmazeutischen zusammensetzungen.
TH14341A (th) สารอาหารหรือสูตรผสมยาสำหรับการให้สู่ร่างกายของสัตว์เคี้ยวเอื้อง
TH61593B (th) สารผสมที่มีเตตราไฮโดรลิพสตาติน
KR830005856A (ko) 소염, 해열 및 진통제 조성물

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LTS LOHMANN THERAPIE-SYSTEME AG, 56626 ANDERNACH,