DE19956568A1
(de)
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
US7601494B2
(en)
|
1999-03-17 |
2009-10-13 |
The University Of North Carolina At Chapel Hill |
Method of screening candidate compounds for susceptibility to biliary excretion
|
US7829693B2
(en)
|
1999-11-24 |
2010-11-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
DE10100586C1
(de)
|
2001-01-09 |
2002-04-11 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Ziegens
|
WO2003070918A2
(en)
|
2002-02-20 |
2003-08-28 |
Ribozyme Pharmaceuticals, Incorporated |
Rna interference by modified short interfering nucleic acid
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
WO2001075164A2
(en)
|
2000-03-30 |
2001-10-11 |
Whitehead Institute For Biomedical Research |
Rna sequence-specific mediators of rna interference
|
TR200401292T3
(tr)
|
2000-12-01 |
2004-07-21 |
Max@Planck@Gesellschaft�Zur�F�Rderung�Der�Wissenschaften |
RNAÁgirişimineÁyolÁaçanÁküçükÁRNAÁmolekülleri
|
WO2003035869A1
(de)
*
|
2001-10-26 |
2003-05-01 |
Ribopharma Ag |
Verwendung einer doppelsträngigen ribonukleinsäure zur gezielten hemmung der expression eines vorgegebenen zielgens
|
EP1438405A1
(de)
*
|
2001-01-09 |
2004-07-21 |
Ribopharma AG |
Verwendung einer doppelsträngigen ribonukleinsäure zur gezielten hemmung der expression eines vorgegebenen zielgens
|
US7767802B2
(en)
|
2001-01-09 |
2010-08-03 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
US8546143B2
(en)
|
2001-01-09 |
2013-10-01 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
US20050148530A1
(en)
|
2002-02-20 |
2005-07-07 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
US9994853B2
(en)
|
2001-05-18 |
2018-06-12 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
CA2921821A1
(en)
|
2001-07-12 |
2003-01-23 |
University Of Massachusetts |
In vivo production of small interfering rnas that mediate gene silencing
|
US10590418B2
(en)
|
2001-07-23 |
2020-03-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for RNAi mediated inhibition of gene expression in mammals
|
PT2280070E
(pt)
|
2001-07-23 |
2015-10-29 |
Univ Leland Stanford Junior |
Métodos e composições para inibição mediada por iarn da expressão génica em mamíferos
|
DE10163098B4
(de)
*
|
2001-10-12 |
2005-06-02 |
Alnylam Europe Ag |
Verfahren zur Hemmung der Replikation von Viren
|
US7745418B2
(en)
|
2001-10-12 |
2010-06-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting viral replication
|
EP1438409A1
(de)
*
|
2001-10-26 |
2004-07-21 |
Ribopharma AG |
Verwendung einer doppelsträngigen ribonukleinsäure zur behandlung einer infektion mit einem (+)-strang-rna-virus
|
DE10202419A1
(de)
|
2002-01-22 |
2003-08-07 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens
|
EP1432724A4
(de)
|
2002-02-20 |
2006-02-01 |
Sirna Therapeutics Inc |
Durch rna-interferenz vermittelte inhibierung von map-kinase-genen
|
US9181551B2
(en)
|
2002-02-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
WO2003099227A2
(en)
|
2002-05-23 |
2003-12-04 |
Ceptyr, Inc. |
Modulation of ptp1b signal transduction by rna interference
|
US7148342B2
(en)
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
US20050042646A1
(en)
|
2002-08-05 |
2005-02-24 |
Davidson Beverly L. |
RNA interference suppresion of neurodegenerative diseases and methods of use thereof
|
EP1389637B1
(de)
*
|
2002-08-05 |
2012-05-30 |
Silence Therapeutics Aktiengesellschaft |
Interferierende RNS Moleküle mit glatten Enden
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
AU2003260370B2
(en)
|
2002-08-05 |
2008-05-22 |
Silence Therapeutics Gmbh |
Further novel forms of interfering RNA molecules
|
ES2665274T5
(es)
*
|
2002-08-05 |
2021-06-30 |
Silence Therapeutics Gmbh |
Nuevas formas adicionales de moléculas de ARN de interferencia
|
US20040241854A1
(en)
|
2002-08-05 |
2004-12-02 |
Davidson Beverly L. |
siRNA-mediated gene silencing
|
DE60328214D1
(de)
|
2002-08-12 |
2009-08-13 |
New England Biolabs Inc |
Verfahren und zusammensetzungen in verbindung mit gen-silencing
|
US7892793B2
(en)
|
2002-11-04 |
2011-02-22 |
University Of Massachusetts |
Allele-specific RNA interference
|
US9879266B2
(en)
|
2002-11-14 |
2018-01-30 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
US9719094B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting SEC61G
|
US9228186B2
(en)
|
2002-11-14 |
2016-01-05 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
US9719092B2
(en)
|
2002-11-14 |
2017-08-01 |
Thermo Fisher Scientific Inc. |
RNAi targeting CNTD2
|
US9771586B2
(en)
|
2002-11-14 |
2017-09-26 |
Thermo Fisher Scientific Inc. |
RNAi targeting ZNF205
|
US10011836B2
(en)
|
2002-11-14 |
2018-07-03 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
US9839649B2
(en)
|
2002-11-14 |
2017-12-12 |
Thermo Fisher Scientific Inc. |
Methods and compositions for selecting siRNA of improved functionality
|
WO2006006948A2
(en)
|
2002-11-14 |
2006-01-19 |
Dharmacon, Inc. |
METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
|
DE10254214A1
(de)
*
|
2002-11-20 |
2004-06-09 |
Beiersdorf Ag |
Oligoribonukleotide zur Behandlung von degenerativen Hauterscheinungen durch RNA-Interferenz
|
JP4526228B2
(ja)
*
|
2002-11-22 |
2010-08-18 |
隆 森田 |
RNAiによる新規治療法および治療剤
|
DE10302421A1
(de)
*
|
2003-01-21 |
2004-07-29 |
Ribopharma Ag |
Doppelsträngige Ribonukleinsäure mit verbesserter Wirksamkeit
|
US20060178327A1
(en)
*
|
2003-05-30 |
2006-08-10 |
Yeung Wah Hin A |
Inhibition of gene expression by delivery of specially selected double stranded or other forms of small interfering RNA precursors enabling the formation and function of small interfering RNA in vivo and in vitro
|
JP4505749B2
(ja)
|
2003-05-30 |
2010-07-21 |
日本新薬株式会社 |
Bcl−2の発現抑制をするオリゴ二本鎖RNAとそれを含有する医薬組成物
|
ES2864206T3
(es)
|
2003-06-02 |
2021-10-13 |
Univ Massachusetts |
Métodos y composiciones para mejorar la eficacia y la especificidad del ARNi
|
EP3502252B1
(de)
|
2003-06-02 |
2023-04-05 |
University of Massachusetts |
Verfahren und zusammensetzungen zur kontrolle der wirksamkeit von rna-silencing
|
US7750144B2
(en)
|
2003-06-02 |
2010-07-06 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
|
EP1486564A1
(de)
*
|
2003-06-13 |
2004-12-15 |
Ribopharma AG |
SiRNA mit erhöhter Stabilität in Serum
|
DK3604537T3
(da)
*
|
2003-06-13 |
2022-02-28 |
Alnylam Europe Ag |
Dobbeltstrenget ribonukleinsyre med forøget effektivitet i en organisme
|
MXPA06002216A
(es)
|
2003-08-28 |
2006-04-27 |
Novartis Ag |
Interferencia de arn doble que tiene extremos romos y modificaciones 3'.
|
US8680063B2
(en)
|
2003-09-12 |
2014-03-25 |
University Of Massachusetts |
RNA interference for the treatment of gain-of-function disorders
|
WO2005027980A1
(en)
|
2003-09-12 |
2005-03-31 |
University Of Massachusetts |
Rna interference for the treatment of gain-of-function disorders
|
US20060134787A1
(en)
|
2004-12-22 |
2006-06-22 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
|
US7858769B2
(en)
|
2004-02-10 |
2010-12-28 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional siNA)
|
WO2005078848A2
(en)
|
2004-02-11 |
2005-08-25 |
University Of Tennessee Research Foundation |
Inhibition of tumor growth and invasion by anti-matrix metalloproteinase dnazymes
|
US20070265220A1
(en)
|
2004-03-15 |
2007-11-15 |
City Of Hope |
Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
|
EP1742958B1
(de)
|
2004-03-15 |
2017-05-17 |
City of Hope |
Verfahren und zusammensetzungen für die spezifische hemmung der genexpression durch doppelstrang-rna
|
WO2005105157A2
(en)
|
2004-04-23 |
2005-11-10 |
The Trustees Of Columbia University In The City Ofnew York |
INHIBITION OF HAIRLESS PROTEIN mRNA
|
US10508277B2
(en)
|
2004-05-24 |
2019-12-17 |
Sirna Therapeutics, Inc. |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
|
EP2290071B1
(de)
|
2004-05-28 |
2014-12-31 |
Asuragen, Inc. |
Verfahren und Zusammensetzungen mit MicroRNA
|
EP2484780A1
(de)
|
2004-07-23 |
2012-08-08 |
The University of North Carolina At Chapel Hill |
Verfahren und Materialien zur Bestimmung der Schmerzempfindlichkeit und Vorhersage und Behandlung zugehöriger Störungen
|
WO2006022689A1
(en)
*
|
2004-08-06 |
2006-03-02 |
Applera Corporation |
Method and compositions for treating diseases targeting cd51
|
JP4468989B2
(ja)
|
2004-08-16 |
2010-05-26 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
Rtp801阻害剤の治療への使用
|
JP5087924B2
(ja)
|
2004-08-26 |
2012-12-05 |
日本新薬株式会社 |
ガラクトース誘導体、薬物担体及び医薬組成物
|
JPWO2006025154A1
(ja)
*
|
2004-08-30 |
2008-05-08 |
国立大学法人岐阜大学 |
修飾オリゴヌクレオチド
|
NZ553987A
(en)
|
2004-09-28 |
2011-01-28 |
Quark Pharmaceuticals Inc |
Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
|
DK2302055T3
(da)
|
2004-11-12 |
2014-10-13 |
Asuragen Inc |
Fremgangsmåder og sammensætninger involverende miRNA og miRNA-inhibitormolekyler
|
US8703769B2
(en)
|
2005-07-15 |
2014-04-22 |
The University Of North Carolina At Chapel Hill |
Use of EGFR inhibitors to prevent or treat obesity
|
WO2007022470A2
(en)
|
2005-08-18 |
2007-02-22 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for treating neurological disease
|
KR20080082956A
(ko)
|
2005-09-15 |
2008-09-12 |
노보솜 아게 |
양쪽성 리포솜의 개선 또는 양쪽성 리포솜에 관련된 개선
|
EP1931789B1
(de)
|
2005-09-20 |
2016-05-04 |
BASF Plant Science GmbH |
VERFAHREN ZUR STEUERUNG DER GENEXPRESSION MITTELS ta- siRNA
|
US8093369B2
(en)
|
2005-10-11 |
2012-01-10 |
Ben Gurion University Of The Negev Research And Development Authority Ltd. |
Compositions for silencing the expression of VDAC1 and uses thereof
|
NL2000439C2
(nl)
|
2006-01-20 |
2009-03-16 |
Quark Biotech |
Therapeutische toepassingen van inhibitoren van RTP801.
|
US7825099B2
(en)
|
2006-01-20 |
2010-11-02 |
Quark Pharmaceuticals, Inc. |
Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
|
JP5093095B2
(ja)
|
2006-03-01 |
2012-12-05 |
日本新薬株式会社 |
ガラクトース誘導体、薬物担体及び医薬組成物
|
US7910566B2
(en)
|
2006-03-09 |
2011-03-22 |
Quark Pharmaceuticals Inc. |
Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
|
FR2898908A1
(fr)
|
2006-03-24 |
2007-09-28 |
Agronomique Inst Nat Rech |
Procede de preparation de cellules aviaires differenciees et genes impliques dans le maintien de la pluripotence
|
GB0608838D0
(en)
|
2006-05-04 |
2006-06-14 |
Novartis Ag |
Organic compounds
|
EP2026843A4
(de)
|
2006-06-09 |
2011-06-22 |
Quark Pharmaceuticals Inc |
Therapeutische verwendungen von rtp801l
|
JP5424885B2
(ja)
|
2006-10-13 |
2014-02-26 |
マリーナ バイオテック,インコーポレイテッド |
両性リポソームにおけるまたは両性リポソームに関する改善、両性リポソームを処方する方法および両性リポソームに充填する方法
|
JP2010507387A
(ja)
|
2006-10-25 |
2010-03-11 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
新規のsiRNAおよびその使用方法
|
US8455188B2
(en)
|
2007-01-26 |
2013-06-04 |
University Of Louisville Research Foundation, Inc. |
Modification of exosomal components for use as a vaccine
|
JP2010518880A
(ja)
|
2007-02-26 |
2010-06-03 |
クアーク・ファーマスーティカルス、インコーポレイテッド |
Rtp801のインヒビター及びその疾患の治療における使用
|
WO2008109546A2
(en)
*
|
2007-03-02 |
2008-09-12 |
Mdrna, Inc. |
Nucleic acid compounds for inhibiting tgfbr gene expression and uses thereof
|
JP5759673B2
(ja)
|
2007-03-21 |
2015-08-05 |
ブルックヘブン サイエンス アソシエイツ,エルエルシー |
組み合わされたヘアピン−アンチセンス組成物および発現を調節するための方法
|
US7812002B2
(en)
|
2007-03-21 |
2010-10-12 |
Quark Pharmaceuticals, Inc. |
Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer
|
DE102007029471A1
(de)
|
2007-06-20 |
2008-12-24 |
Novosom Ag |
Neue fakultativ kationische Sterole
|
DK2170403T3
(da)
|
2007-06-27 |
2014-06-16 |
Quark Pharmaceuticals Inc |
Sammensætninger og fremgangsmåder til hæmning af ekspressionen af proapoptotiske gener
|
WO2009036332A1
(en)
|
2007-09-14 |
2009-03-19 |
Asuragen, Inc. |
Micrornas differentially expressed in cervical cancer and uses thereof
|
JP5646997B2
(ja)
|
2007-10-03 |
2014-12-24 |
クォーク ファーマシューティカルズ インコーポレーティッドQuark Pharmaceuticals,Inc. |
新規siRNA構造
|
WO2009070805A2
(en)
|
2007-12-01 |
2009-06-04 |
Asuragen, Inc. |
Mir-124 regulated genes and pathways as targets for therapeutic intervention
|
US8614311B2
(en)
|
2007-12-12 |
2013-12-24 |
Quark Pharmaceuticals, Inc. |
RTP801L siRNA compounds and methods of use thereof
|
KR100949791B1
(ko)
*
|
2007-12-18 |
2010-03-30 |
이동기 |
오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도
|
WO2009102427A2
(en)
|
2008-02-11 |
2009-08-20 |
Rxi Pharmaceuticals Corp. |
Modified rnai polynucleotides and uses thereof
|
WO2009137807A2
(en)
|
2008-05-08 |
2009-11-12 |
Asuragen, Inc. |
Compositions and methods related to mirna modulation of neovascularization or angiogenesis
|
WO2009147684A2
(en)
|
2008-06-06 |
2009-12-10 |
Quark Pharmaceuticals, Inc. |
Compositions and methods for treatment of ear disorders
|
TWI455944B
(zh)
|
2008-07-01 |
2014-10-11 |
Daiichi Sankyo Co Ltd |
雙股多核苷酸
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
EP2326351B1
(de)
|
2008-08-19 |
2017-12-27 |
Nektar Therapeutics |
Konjugate von kurzen interferierenden nukleinsäuren
|
US10138485B2
(en)
|
2008-09-22 |
2018-11-27 |
Rxi Pharmaceuticals Corporation |
Neutral nanotransporters
|
WO2010059226A2
(en)
|
2008-11-19 |
2010-05-27 |
Rxi Pharmaceuticals Corporation |
Inhibition of map4k4 through rnai
|
SG171952A1
(en)
|
2008-12-04 |
2011-07-28 |
Opko Ophthalmics Llc |
Compositions and methods for selective inhibition of pro-angiogenic vegf isoforms
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
US9745574B2
(en)
|
2009-02-04 |
2017-08-29 |
Rxi Pharmaceuticals Corporation |
RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
BR112012000255B1
(pt)
|
2009-07-09 |
2022-11-29 |
Marina Biotech, Inc |
Compostos compreendendo imino lipídios e composição compreendendo os ditos compostos
|
WO2011035065A1
(en)
|
2009-09-17 |
2011-03-24 |
Nektar Therapeutics |
Monoconjugated chitosans as delivery agents for small interfering nucleic acids
|
CA2776568A1
(en)
|
2009-11-26 |
2011-06-03 |
Quark Pharmaceuticals, Inc. |
Sirna compounds comprising terminal substitutions
|
US8293718B2
(en)
|
2009-12-18 |
2012-10-23 |
Novartis Ag |
Organic compositions to treat HSF1-related diseases
|
WO2011083147A1
(en)
|
2010-01-08 |
2011-07-14 |
Cemm-Forschungsinstitut Für Molekulare Medizin Gmbh |
Wave1 inhibition in the medical intervention of inflammatory diseases and/or infections caused by a pathogen
|
MX2012009318A
(es)
|
2010-02-10 |
2012-09-07 |
Novartis Ag |
Metodos y compuestos para el crecimiento muscular.
|
KR20180044433A
(ko)
|
2010-03-24 |
2018-05-02 |
알엑스아이 파마슈티칼스 코포레이션 |
진피 및 섬유증성 적응증에서의 rna 간섭
|
RU2615143C2
(ru)
|
2010-03-24 |
2017-04-04 |
Адвирна |
Самодоставляющие PHKi соединения уменьшенного размера
|
US9095504B2
(en)
|
2010-03-24 |
2015-08-04 |
Rxi Pharmaceuticals Corporation |
RNA interference in ocular indications
|
US20130116304A1
(en)
|
2010-04-19 |
2013-05-09 |
Ernst R. Werner |
Tmem195 encodes for tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity
|
EP3372684B1
(de)
|
2010-08-24 |
2020-10-07 |
Sirna Therapeutics, Inc. |
Einsträngige rnai-mittel mit einem internen nukleinsäurefreien spacer
|
WO2012028703A1
(en)
|
2010-09-02 |
2012-03-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for the prognosis of the progression of cancer
|
EP2433644A1
(de)
|
2010-09-22 |
2012-03-28 |
IMBA-Institut für Molekulare Biotechnologie GmbH |
Brustkrebstherapeutika
|
JP5795072B2
(ja)
|
2010-10-22 |
2015-10-14 |
ソンギュングヮン ユニバーシティ ファウンデーション フォー コーポレート コラボレーション |
Rna干渉を誘導する核酸分子及びその用途
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
US9833439B2
(en)
|
2011-05-25 |
2017-12-05 |
Universite Paris Descartes |
ERK inhibitors for use in treating spinal muscular atrophy
|
US8951966B2
(en)
|
2011-07-01 |
2015-02-10 |
Ngm Biopharmaceuticals, Inc. |
Compositions comprising variants and fusions of FGF19 polypeptides, and uses and methods thereof for treatment of metabolic disorders and diseases
|
WO2013040251A2
(en)
|
2011-09-13 |
2013-03-21 |
Asurgen, Inc. |
Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease
|
WO2013053919A2
(en)
|
2011-10-14 |
2013-04-18 |
Inserm |
Biomarkers of renal disorders
|
US10023862B2
(en)
|
2012-01-09 |
2018-07-17 |
Arrowhead Pharmaceuticals, Inc. |
Organic compositions to treat beta-catenin-related diseases
|
WO2013104798A1
(en)
|
2012-01-12 |
2013-07-18 |
Cemm - Center For Molecular Medicine Of The Austrian Academy Of Sciences |
Modulators of immune responses
|
CN108148838A
(zh)
|
2012-05-22 |
2018-06-12 |
奥利克斯医药有限公司 |
具有细胞内穿透能力的诱导rna干扰的核酸分子及用途
|
EP2700949A1
(de)
|
2012-08-24 |
2014-02-26 |
IMG Institut für medizinische Genomforschung Planungsgesellschaft M.B.H. |
Verwendung von Biliverdinreduktaseproteinen als Krebsmarker
|
EP2914260A1
(de)
|
2012-10-31 |
2015-09-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Verfahren zur vorbeugung des antiphospholipid-syndroms (aps)
|
EP3798228A1
(de)
|
2012-11-28 |
2021-03-31 |
NGM Biopharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur behandlung von stoffwechselstörungen und -erkrankungen
|
US9290557B2
(en)
|
2012-11-28 |
2016-03-22 |
Ngm Biopharmaceuticals, Inc. |
Compositions comprising variants and fusions of FGF19 polypeptides
|
CN108888757A
(zh)
|
2012-12-27 |
2018-11-27 |
恩格姆生物制药公司 |
用于调节胆汁酸体内稳态及治疗胆汁酸紊乱和疾病的方法
|
US9273107B2
(en)
|
2012-12-27 |
2016-03-01 |
Ngm Biopharmaceuticals, Inc. |
Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
KR102178945B1
(ko)
|
2013-10-28 |
2020-11-13 |
엔지엠 바이오파마슈티컬스, 아이엔씨. |
암 모델 및 관련 방법
|
EP3079707A4
(de)
|
2013-12-02 |
2017-10-18 |
RXi Pharmaceuticals Corporation |
Immuntherapie für krebs
|
BR112016017248A8
(pt)
|
2014-01-24 |
2018-04-17 |
Ngm Biopharmaceuticals Inc |
anticorpo ou fragmento seu, agente de ligação, animal transgênico, hibridoma, vetor, composição farmacêutica, método de indução de sinalização de semelhantes a fgf19 e/ou fgf21, método para ativar um complexo klotho beta/receptor de fgf, método para melhorar o metabolismo da glicose em um indivíduo, método de detecção da presença de klotho beta, uso do anticorpo ou fragmento seu, uso da composição farmacêutica, método de tratamento e método para melhorar parâmetros metabólicos
|
KR102228828B1
(ko)
|
2014-03-11 |
2021-03-16 |
셀렉티스 |
동종이형 이식에 양립성인 t-세포들을 만들어내는 방법
|
EP3137119B1
(de)
|
2014-04-28 |
2020-07-01 |
Phio Pharmaceuticals Corp. |
Verfahren zur behandlung von krebs mithilfe von einer nukleinsaüre gegen mdm2
|
US10398758B2
(en)
|
2014-05-28 |
2019-09-03 |
Ngm Biopharmaceuticals, Inc. |
Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions
|
CA2951153A1
(en)
|
2014-06-16 |
2015-12-23 |
Ngm Biopharmaceuticals, Inc. |
Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
|
CN107073294A
(zh)
|
2014-09-05 |
2017-08-18 |
阿克赛医药公司 |
使用靶向tyr或mmp1的核酸治疗老化和皮肤病症的方法
|
KR102569907B1
(ko)
|
2014-10-23 |
2023-08-24 |
엔지엠 바이오파마슈티컬스, 아이엔씨. |
펩티드 변이체를 포함하는 약제학적 조성물 및 그의 사용 방법
|
WO2016073855A1
(en)
|
2014-11-07 |
2016-05-12 |
Ngm Biopharmaceuticals, Inc. |
Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
|
US10500273B2
(en)
|
2015-03-02 |
2019-12-10 |
180 Therapeutics Lp |
Method of treating a localized fibrotic disorder using an IL-33 antagonist
|
WO2017007825A1
(en)
|
2015-07-06 |
2017-01-12 |
Rxi Pharmaceuticals Corporation |
Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
|
JP6983752B2
(ja)
|
2015-07-06 |
2021-12-17 |
フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. |
スーパーオキシドディスムターゼ1(sod1)を標的とする核酸分子
|
US10800843B2
(en)
|
2015-07-29 |
2020-10-13 |
Ngm Biopharmaceuticals, Inc. |
Beta klotho-binding proteins
|
WO2017029391A1
(en)
|
2015-08-20 |
2017-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating cancer
|
CA3002744A1
(en)
|
2015-10-19 |
2017-04-27 |
Rxi Pharmaceuticals Corporation |
Reduced size self-delivering nucleic acid compounds targeting long non-coding rna
|
EP3377090B1
(de)
|
2015-11-09 |
2021-04-07 |
NGM Biopharmaceuticals, Inc. |
Verfahren zur behandlung von gallensäurebedingten erkrankungen
|
KR20180071362A
(ko)
|
2015-11-16 |
2018-06-27 |
올릭스 주식회사 |
MyD88 또는 TLR3을 타겟팅하는 RNA 복합체를 이용한 연령-관련 황반 변성의 치료
|
CN108779463B
(zh)
|
2016-02-02 |
2022-05-24 |
奥利克斯医药有限公司 |
使用靶向IL4Rα、TRPA1或F2RL1的RNA复合物治疗特应性皮炎和哮喘
|
WO2017134526A1
(en)
|
2016-02-02 |
2017-08-10 |
Olix Pharmaceuticals, Inc. |
Treatment of angiogenesis-associated diseases using rna complexes that target angpt2 and pdgfb
|
EP3423568A4
(de)
|
2016-03-04 |
2019-11-13 |
University Of Louisville Research Foundation, Inc. |
Verfahren und zusammensetzungen zur ex-vivo-vermehrung von sehr kleinen embryonalen stammzellen (vsels)
|
RU2759737C2
(ru)
|
2016-03-31 |
2021-11-17 |
Этрис Гмбх |
Новые минимальные utr-последовательности
|
MA45469A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques de bêta-caténine et leurs utilisations
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
MA45349A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques egfr et leurs utilisations
|
MA45470A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Acides nucléiques kras et leurs utilisations
|
CA3020487C
(en)
|
2016-04-11 |
2022-05-31 |
Olix Pharmaceuticals, Inc. |
Treatment of idiopathic pulmonary fibrosis using rna complexes that target connective tissue growth factor
|
KR101916652B1
(ko)
|
2016-06-29 |
2018-11-08 |
올릭스 주식회사 |
작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
|
US20190367930A1
(en)
|
2016-07-29 |
2019-12-05 |
Danmarks Tekniske Universitet |
Methods for decoupling cell growth from production of biochemicals and recombinant polypeptides
|
EP3503882A4
(de)
|
2016-08-26 |
2020-07-29 |
NGM Biopharmaceuticals, Inc. |
Verfahren zur behandlung von fibroblastenwachstumsfaktor-19-vermittelten karzinomen und tumoren
|
KR20190108167A
(ko)
|
2017-02-10 |
2019-09-23 |
성균관대학교산학협력단 |
Rna 간섭을 위한 긴 이중가닥 rna
|
US20200199541A1
(en)
|
2017-06-16 |
2020-06-25 |
Imba - Institut Für Molekulare Biotechnologie Gmbh |
Blood vessel organoid, methods of producing and using said organoids
|
MX2020005860A
(es)
|
2017-12-06 |
2020-09-09 |
Avidity Biosciences Inc |
Composiciones y metodos de tratamiento de atrofia muscular y distrofia miotonica.
|
CN108535480B
(zh)
*
|
2018-03-05 |
2020-03-06 |
南通大学附属医院 |
EphA8基因在制备抗乳腺癌药物及其诊断试剂盒中的应用
|
CN108490180B
(zh)
*
|
2018-03-12 |
2020-03-10 |
南通大学附属医院 |
EphA8基因在制备胃癌药物及其诊断试剂盒中的应用
|
JP2023537798A
(ja)
|
2020-03-19 |
2023-09-06 |
アビディティー バイオサイエンシーズ,インク. |
顔面肩甲上腕型筋ジストロフィーを処置するための組成物および方法
|
CN116887812A
(zh)
|
2021-02-26 |
2023-10-13 |
埃泽瑞斯公司 |
用于气溶胶形成的制剂以及用于递送核酸的气溶胶
|
WO2024042236A1
(en)
|
2022-08-26 |
2024-02-29 |
Ethris Gmbh |
Stable lipid or lipidoid nanoparticle suspensions
|
EP4327829A1
(de)
|
2022-08-26 |
2024-02-28 |
Ethris GmbH |
Stabilisierung von lipid- oder lipidoidnanopartikelsuspensionen
|