DE3878468D1 - Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus. - Google Patents

Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.

Info

Publication number
DE3878468D1
DE3878468D1 DE8888909879T DE3878468T DE3878468D1 DE 3878468 D1 DE3878468 D1 DE 3878468D1 DE 8888909879 T DE8888909879 T DE 8888909879T DE 3878468 T DE3878468 T DE 3878468T DE 3878468 D1 DE3878468 D1 DE 3878468D1
Authority
DE
Germany
Prior art keywords
glycoproteins
respiratory syncytial
syncytial virus
human respiratory
chimarene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888909879T
Other languages
English (en)
Other versions
DE3878468T2 (de
Inventor
Michael Wathen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DE3878468D1 publication Critical patent/DE3878468D1/de
Application granted granted Critical
Publication of DE3878468T2 publication Critical patent/DE3878468T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE8888909879T 1987-12-23 1988-10-31 Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus. Expired - Lifetime DE3878468T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13738787A 1987-12-23 1987-12-23
PCT/US1988/003784 WO1989005823A1 (en) 1987-12-23 1988-10-31 Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus

Publications (2)

Publication Number Publication Date
DE3878468D1 true DE3878468D1 (de) 1993-03-25
DE3878468T2 DE3878468T2 (de) 1993-06-09

Family

ID=22477194

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888909879T Expired - Lifetime DE3878468T2 (de) 1987-12-23 1988-10-31 Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.

Country Status (14)

Country Link
US (2) US5194595A (de)
EP (1) EP0396563B1 (de)
JP (1) JP2716503B2 (de)
KR (1) KR0137963B1 (de)
AT (1) ATE85622T1 (de)
AU (1) AU617739B2 (de)
CA (1) CA1320163C (de)
DE (1) DE3878468T2 (de)
DK (1) DK173175B1 (de)
FI (1) FI102382B1 (de)
HK (1) HK166295A (de)
MX (1) MX9203458A (de)
NO (1) NO300254B1 (de)
WO (1) WO1989005823A1 (de)

Families Citing this family (37)

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GB8914968D0 (en) * 1989-06-29 1989-08-23 Connaught Lab Production of virus and purification of viral envelope proteins for vaccine use
US6004563A (en) * 1990-11-07 1999-12-21 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
US5824307A (en) 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
GB9200117D0 (en) * 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
TW275632B (de) * 1992-04-21 1996-05-11 American Cyanamid Co
EP0678102A1 (de) * 1993-01-08 1995-10-25 The Upjohn Company Verfahren zur reinigung und rückfaltung vom fg glykoprtein des respiratorischen sincytialvirus
EP0705109B2 (de) * 1993-05-25 2004-01-02 American Cyanamid Company Adjuvantien für impfstoffe gegen das respiratorische synzitialvirus
WO1995019568A1 (en) * 1994-01-14 1995-07-20 Matthias Rath Hydrophilic signal oligopeptides and methods of therapeutic use
US7300918B2 (en) 1994-01-14 2007-11-27 Matthias Rath Method of producing vaccines from protein signal oligopeptides
FR2718452B1 (fr) 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
US5716821A (en) * 1994-09-30 1998-02-10 Uab Research Foundation Prevention and treatment of respiratory tract disease
US5789229A (en) * 1994-09-30 1998-08-04 Uab Research Foundation Stranded RNA virus particles
FR2726472B1 (fr) 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
DE4442114A1 (de) * 1994-11-25 1996-05-30 Buna Sow Leuna Olefinverb Gmbh Nitrit-, phosphat- und aminfreies Kühl- und Wärmeübertragungsmittel
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US6015664A (en) * 1995-11-03 2000-01-18 Mcw Research Foundation Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B
WO1998018819A1 (en) * 1996-10-29 1998-05-07 Smithkline Beecham Biologicals S.A. Purification of respiratory syncytial virus antigens
US6103466A (en) * 1997-07-14 2000-08-15 University Of Liege Double-muscling in mammals
WO1999002667A1 (en) * 1997-07-14 1999-01-21 University Of Liege Mutations in the myostation gene cause double-muscling in mammals
US20070067859A1 (en) * 1997-07-14 2007-03-22 Michel Georges Double-muscling in mammals
US6699478B1 (en) * 1997-09-19 2004-03-02 Wyeth Holdings Corporation Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus
GB9909077D0 (en) 1999-04-20 1999-06-16 Smithkline Beecham Biolog Novel compositions
ATE474854T1 (de) * 2000-01-27 2010-08-15 Medimmune Llc Rsv neutralisierende antikörper mit sehr hohen affinität
EP2341075A1 (de) * 2000-03-01 2011-07-06 MedImmune, LLC Anti-rsv-f-protein-antikörper
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
EA010404B1 (ru) * 2004-05-24 2008-08-29 Полимун Сайнтифик Иммунбиологише Форшунг Гмбх Сверхзагрузка липосом для доставки лекарственных веществ
EP1812068A4 (de) * 2004-10-29 2010-06-09 Medimmune Inc Verfahren zur prävention und behandlung von rsv-infektionen und verwandten leiden
EP1997830A1 (de) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV-spezifische Bindemoleküle und Mittel zu ihrer Herstellung
CN101952321B (zh) 2007-12-24 2016-05-11 葛兰素史密斯克莱生物公司 重组rsv抗原
EA201170217A1 (ru) * 2008-07-18 2011-08-30 АйДи БАЙОМЕДИКАЛ КОРПОРЕЙШН ОФ КВЕБЕК Гибридные полипептидные антигены респираторно-синцитиального вируса
DK2445526T3 (en) 2009-06-24 2016-06-27 Glaxosmithkline Biologicals Sa Recombinant RSV antigens.
EP3178490B1 (de) 2009-07-15 2022-04-20 GlaxoSmithKline Biologicals S.A. Rsv-f-proteinzusammensetzungen und verfahren zu ihrer herstellung
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
SG11201500696VA (en) 2012-08-01 2015-02-27 Bavarian Nordic As Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
AU605476B2 (en) * 1986-01-14 1991-01-17 University Of North Carolina, The Vaccines for human respiratory virus
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
SG106639A1 (en) * 2000-10-10 2004-10-29 Gen Electric Apparatus and method for introducing small amounts of refractory elements into a vapor deposition coating

Also Published As

Publication number Publication date
FI102382B (fi) 1998-11-30
DK173175B1 (da) 2000-03-06
WO1989005823A1 (en) 1989-06-29
NO902802L (no) 1990-06-22
NO902802D0 (no) 1990-06-22
AU2785089A (en) 1989-07-19
MX9203458A (es) 1992-09-01
CA1320163C (en) 1993-07-13
JPH03501723A (ja) 1991-04-18
HK166295A (en) 1995-11-03
EP0396563A1 (de) 1990-11-14
DK153290D0 (da) 1990-06-22
EP0396563B1 (de) 1993-02-10
NO300254B1 (no) 1997-05-05
JP2716503B2 (ja) 1998-02-18
DE3878468T2 (de) 1993-06-09
DK153290A (da) 1990-08-16
FI903154A0 (fi) 1990-06-21
ATE85622T1 (de) 1993-02-15
US5194595A (en) 1993-03-16
US5288630A (en) 1994-02-22
KR900700508A (ko) 1990-08-13
FI102382B1 (fi) 1998-11-30
AU617739B2 (en) 1991-12-05
KR0137963B1 (ko) 1998-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US