DE3872382T2 - Pharmazeutische zusammensetzungen mit verlaengerter wirkung und verfahren zu ihrer herstellung. - Google Patents

Pharmazeutische zusammensetzungen mit verlaengerter wirkung und verfahren zu ihrer herstellung.

Info

Publication number
DE3872382T2
DE3872382T2 DE8888120153T DE3872382T DE3872382T2 DE 3872382 T2 DE3872382 T2 DE 3872382T2 DE 8888120153 T DE8888120153 T DE 8888120153T DE 3872382 T DE3872382 T DE 3872382T DE 3872382 T2 DE3872382 T2 DE 3872382T2
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
production
extended effect
active substance
microporous support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888120153T
Other languages
English (en)
Other versions
DE3872382D1 (de
Inventor
Mara Lucia Lovrecich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Vectorpharma International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma International SpA filed Critical Vectorpharma International SpA
Application granted granted Critical
Publication of DE3872382D1 publication Critical patent/DE3872382D1/de
Publication of DE3872382T2 publication Critical patent/DE3872382T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
DE8888120153T 1988-04-08 1988-12-02 Pharmazeutische zusammensetzungen mit verlaengerter wirkung und verfahren zu ihrer herstellung. Expired - Fee Related DE3872382T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8820145A IT1216570B (it) 1988-04-08 1988-04-08 Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.

Publications (2)

Publication Number Publication Date
DE3872382D1 DE3872382D1 (de) 1992-07-30
DE3872382T2 true DE3872382T2 (de) 1992-12-10

Family

ID=11164167

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888120153T Expired - Fee Related DE3872382T2 (de) 1988-04-08 1988-12-02 Pharmazeutische zusammensetzungen mit verlaengerter wirkung und verfahren zu ihrer herstellung.

Country Status (6)

Country Link
US (1) US5008114A (de)
EP (1) EP0336014B1 (de)
AT (1) ATE77547T1 (de)
DE (1) DE3872382T2 (de)
ES (1) ES2042700T3 (de)
IT (1) IT1216570B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290570A (en) * 1989-05-30 1994-03-01 Purepac, Inc. Lotions containing liquid-loaded powder
FR2694701B1 (fr) * 1990-04-18 1996-01-19 Biagianti Irene Application des zeolithes naturelles a l'homme et a l'environnement.
IT1243745B (it) * 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
US5225204A (en) * 1991-11-05 1993-07-06 Chen Jivn Ren Stable dosage of levothyroxine sodium and process of production
US5409903A (en) * 1992-02-18 1995-04-25 Urecap Corporation Method and compositions for the treatment of H. pylori and dermatitis
US5298261A (en) * 1992-04-20 1994-03-29 Oregon Freeze Dry, Inc. Rapidly distintegrating tablet
AU4932493A (en) * 1992-09-25 1994-04-26 Dynagen, Inc. An immunobooster for delayed release of immunogen
EP0669128B1 (de) * 1992-11-17 2000-01-05 Yoshitomi Pharmaceutical Industries, Ltd. Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung
CA2151260A1 (en) * 1993-02-23 1994-09-01 Pankaj B. Gala A process for the preparation of substantially alcohol free pharmaceutical compositions
ATE288270T1 (de) * 1993-11-19 2005-02-15 Janssen Pharmaceutica Nv Mikroverkapselte 1,2-benzazole
DE4416001C2 (de) * 1994-05-06 1997-12-11 Feinchemie Gmbh Sebnitz Komposite zur steuerbaren Wirkstoff-Freisetzung
CA2213638C (en) * 1995-02-24 2004-05-04 Nanosystems L.L.C. Aerosols containing nanoparticle dispersions
US6764690B2 (en) 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
ATE301102T1 (de) * 1996-05-29 2005-08-15 Delsitech Oy Lösliche oxide für biologische anwendungen
US7101575B2 (en) 1998-03-19 2006-09-05 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
NZ513013A (en) * 1999-02-22 2002-11-26 Bioxid Oy Biodegradable ceramic fibres from silica sols useful in delivery devices for biologically active agents
GB9904485D0 (en) * 1999-02-27 1999-04-21 Procter & Gamble Method for protecting and/or controlled release of active ingredient
ATE226267T1 (de) * 1999-06-10 2002-11-15 Max Planck Gesellschaft Einkapselung von kristallen mit mehrschichtigem überzug
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
EP1269994A3 (de) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmazeutische Zusammensetzungen die ein Arzneimittel und die Konzentration verbesserende Polymere enthalten
KR100759635B1 (ko) * 2001-06-22 2007-09-17 화이자 프로덕츠 인코포레이티드 비정질 약물의 흡착체의 약학 조성물
ATE395044T1 (de) 2002-02-01 2008-05-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen amorpher dispersionen von wirkstoffen und lipophiler mikrophasenbildender materialien
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
ATE540671T1 (de) 2003-08-04 2012-01-15 Bend Res Inc Pharmazeutische zusammensetzungen von adsorbaten von amorphen arzneimitteln und lipophilen mikrophasen-bildenden materialien
US7387793B2 (en) * 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
DE102004013637A1 (de) 2004-03-19 2005-10-13 Capsulution Nanoscience Ag Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
FI20070174A0 (fi) * 2007-02-28 2007-02-28 Delsitech Oy Menetelmä silikakoostumusten valmistamiseksi, silikakoostumukset ja niiden käytöt
ITMI20071930A1 (it) * 2007-10-05 2009-04-06 Sasol Italy S P A Composizioni farmaceutiche a base di zeoliti porose quali mezzi di rilascio di molecole farmacologicamente attive e relativo uso
NO2403482T3 (de) 2009-03-04 2018-05-26
JP5691051B2 (ja) 2009-05-08 2015-04-01 エンプリキュア・アクチエボラゲット ジオポリマー結合剤を含む持続薬物送達用組成物
KR20140003405A (ko) 2010-09-07 2014-01-09 오렉쏘 에이비 경피 약물 투여 장치
US9526701B2 (en) * 2011-12-20 2016-12-27 Keith R. Latham Sustained drug release and improved product stability using non-covalent particle coating methods
US10835495B2 (en) 2012-11-14 2020-11-17 W. R. Grace & Co.-Conn. Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same
WO2015153613A1 (en) * 2014-03-31 2015-10-08 Massachusetts Institute Of Technology Porous materials containing compounds including pharmaceutically active species
GB201502073D0 (en) 2015-02-09 2015-03-25 Cubic Pharmaceuticals Ltd And Delta Pharmaceuticals Ltd HDEG technology

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923969A (en) * 1973-06-12 1975-12-02 Battelle Institut E V Carrier system for a drug with sustained release
US4013785A (en) * 1975-03-21 1977-03-22 Bristol-Myers Company Apap tablet containing fumed silica and process for manufacturing same
DE2845326C2 (de) * 1978-10-18 1985-05-23 Beiersdorf Ag, 2000 Hamburg Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
US4834978A (en) * 1984-10-01 1989-05-30 Biotek, Inc. Method of transdermal drug delivery
GB8606468D0 (en) * 1986-03-15 1986-04-23 Sds Biotech Uk Ltd Therapeutic compositions
US4775535A (en) * 1986-04-04 1988-10-04 Hans Lowey Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics
JPS6327502A (ja) * 1986-07-22 1988-02-05 Agency Of Ind Science & Technol シクロデキストリン−シリカ複合体及びその製造方法

Also Published As

Publication number Publication date
EP0336014A1 (de) 1989-10-11
ATE77547T1 (de) 1992-07-15
EP0336014B1 (de) 1992-06-24
IT1216570B (it) 1990-03-08
IT8820145A0 (it) 1988-04-08
US5008114A (en) 1991-04-16
ES2042700T3 (es) 1993-12-16
DE3872382D1 (de) 1992-07-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: HANKE, H., DIPL.-ING. DIPL.-WIRTSCH.-ING., PAT.-ANW., 80802 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: EURAND INTERNATIONAL S.P.A., MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee