DE3854951D1 - Verfahren für Immunochromatographie mit Kolloidteilchen - Google Patents

Verfahren für Immunochromatographie mit Kolloidteilchen

Info

Publication number
DE3854951D1
DE3854951D1 DE3854951T DE3854951T DE3854951D1 DE 3854951 D1 DE3854951 D1 DE 3854951D1 DE 3854951 T DE3854951 T DE 3854951T DE 3854951 T DE3854951 T DE 3854951T DE 3854951 D1 DE3854951 D1 DE 3854951D1
Authority
DE
Germany
Prior art keywords
meta
protein
proteins
soluble protein
aqueous medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3854951T
Other languages
English (en)
Other versions
DE3854951T2 (de
DE3854951T3 (de
Inventor
Shanfun Ching
Julian Gordon
Patricia A Billing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22107719&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3854951(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE3854951D1 publication Critical patent/DE3854951D1/de
Publication of DE3854951T2 publication Critical patent/DE3854951T2/de
Application granted granted Critical
Publication of DE3854951T3 publication Critical patent/DE3854951T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives
DE3854951T 1987-07-13 1988-07-12 Verfahren für Immunochromatographie mit Kolloidteilchen Expired - Lifetime DE3854951T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/072,459 US5120643A (en) 1987-07-13 1987-07-13 Process for immunochromatography with colloidal particles
US72459 1987-07-13

Publications (3)

Publication Number Publication Date
DE3854951D1 true DE3854951D1 (de) 1996-03-14
DE3854951T2 DE3854951T2 (de) 1996-11-07
DE3854951T3 DE3854951T3 (de) 2004-09-02

Family

ID=22107719

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3854951T Expired - Lifetime DE3854951T3 (de) 1987-07-13 1988-07-12 Verfahren für Immunochromatographie mit Kolloidteilchen
DE3856544T Expired - Lifetime DE3856544T2 (de) 1987-07-13 1988-07-12 Verfahren zur Lagerung labiler Proteine

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3856544T Expired - Lifetime DE3856544T2 (de) 1987-07-13 1988-07-12 Verfahren zur Lagerung labiler Proteine

Country Status (8)

Country Link
US (3) US5120643A (de)
EP (2) EP0299428B2 (de)
JP (1) JPH0760159B2 (de)
AT (2) ATE227427T1 (de)
AU (1) AU614294B2 (de)
CA (1) CA1306675C (de)
DE (2) DE3854951T3 (de)
ES (2) ES2186697T3 (de)

Families Citing this family (407)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US5514602A (en) * 1986-06-09 1996-05-07 Ortho Diagnostic Systems, Inc. Method of producing a metal sol reagent containing colloidal metal particles
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
USRE38430E1 (en) 1987-03-27 2004-02-17 Becton, Dickinson And Company Solid phase chromatographic immunoassay
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
DE3856421T2 (de) 1987-04-27 2000-12-14 Unilever Nv Spezifische Bindungstestverfahren
DE3715485A1 (de) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Stabilisierung von ss-galactosidase
US4954452A (en) * 1987-07-09 1990-09-04 Abbott Laboratories Non-metal colloidal particle immunoassay
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
EP0317001B1 (de) * 1987-11-16 1993-02-03 Janssen Pharmaceutica N.V. Auf ultrakleine kolloidale Metallteilchen gegründetes, allgemein anwendbares Nachweissystem
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
US5459080A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Ion-capture assays using a specific binding member conjugated to carboxymethylamylose
US5459078A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Methods and reagents for performing ion-capture digoxin assays
US5866322A (en) * 1988-01-29 1999-02-02 Abbott Laboratories Method for performing Rubella assay
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
IT1227293B (it) * 1988-10-06 1991-04-05 Boehringer Biochemia Srl Dispositivo e metodo per la diagnosi di gravidanza
US5348891A (en) * 1988-11-15 1994-09-20 H.B.T. Holland Biotechnology Method for an increased visualization of the reaction product of a specifically binding substance and a corresponding bindable substance and test kit therefor
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5411858A (en) * 1989-05-17 1995-05-02 Actimed Laboratories, Inc. Manufacturing process for sample initiated assay device
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
JP3070764B2 (ja) * 1990-03-12 2000-07-31 バイオサイト・ダイアグノスティックス・インコーポレイテッド 生物学的検定装置及びそれを用いた検定方法
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
ES2092523T3 (es) * 1990-05-09 1996-12-01 Abbott Lab Ensayos que utilizan enlaces con recuperacion de conjugado.
DE4024544A1 (de) * 1990-08-02 1992-02-06 Boehringer Mannheim Gmbh Analyseelement und verfahren zu seiner herstellung
US5266497A (en) * 1990-08-31 1993-11-30 Japan Synthetic Rubber Co., Ltd. Immunochromatographic assay with improved colored latex
WO1992005440A1 (en) * 1990-09-26 1992-04-02 Akers Research Corporation Improved ligand assay
DE69229334T2 (de) * 1991-01-11 1999-12-16 Quidel Corp Einstufiges querfluss analysenverfahren und ein darin verwendeter nichtsaugfähiger träger
JP3108115B2 (ja) * 1991-03-28 2000-11-13 ロート製薬株式会社 イムノクロマトグラフ法による物質検出法
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5869345A (en) 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5468648A (en) 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
EP0641442B1 (de) * 1991-05-30 1997-12-17 Abbott Laboratories Vorrichtungen zur ausführung von ioneneinfangassays
CA2110920A1 (en) * 1991-06-13 1992-12-23 Sinfu Tzeng Assay for the detection of specific ligands
US5686315A (en) * 1991-06-14 1997-11-11 Quidel Corporation Assay device for one step detection of analyte
JPH0545361A (ja) * 1991-06-27 1993-02-23 Idemitsu Petrochem Co Ltd 液体試料の分析方法及び該方法に用いる液体試料分析用基板
EP0643837B1 (de) * 1992-01-22 1998-12-23 Actimed Laboratories, Inc. Herstellungsverfahren für eine durch die probe initiierte assayvorrichtung
DE4202850A1 (de) * 1992-01-31 1993-08-05 Boehringer Mannheim Gmbh Analysenelement fuer immunoassays
WO1993018398A1 (en) * 1992-03-10 1993-09-16 Quidel Corporation Red blood cell separation means for specific binding assays
US5310647A (en) * 1992-04-01 1994-05-10 Cherrystone Corporation Detection and measurement of destructive and polymer forming enzymes by colloidal flocculation
US5372783A (en) * 1992-08-03 1994-12-13 Sapidyne, Inc. Assay system
US6664114B1 (en) 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
US5356782A (en) * 1992-09-03 1994-10-18 Boehringer Mannheim Corporation Analytical test apparatus with on board negative and positive control
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5807752A (en) * 1992-09-11 1998-09-15 Boehringer Mannheim Corporation Assay using an unblocked solid phase with immobilized analyte binding partner
US5736410A (en) * 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
US5500375A (en) * 1993-04-13 1996-03-19 Serex, Inc. Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
JP3479100B2 (ja) 1993-06-02 2003-12-15 帝国臓器製薬株式会社 免疫化学的簡易半定量方法および装置
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
DE4331596A1 (de) * 1993-09-17 1995-03-23 Boehringer Mannheim Gmbh Verfahren zur quantitativen Analyse von Probenflüssigkeiten
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
JP3755826B2 (ja) * 1993-12-09 2006-03-15 触媒化成工業株式会社 アルミナの製造方法と装置
AU1739395A (en) * 1994-02-07 1995-08-21 United States Of America, As Represented By The Secretary Of Agriculture, The Detection of wheat that has experienced elevated temperatures during the grain filling period
ATE196689T1 (de) * 1994-03-30 2000-10-15 Johnson & Johnson Clin Diag Verringerung der störung in chemilumineszierenden dünnschicht-immuntests
US5597700A (en) * 1994-04-28 1997-01-28 California Research, Llc Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method
US5658747A (en) * 1994-05-10 1997-08-19 Biocontrol System, Inc. Compositions and methods for control of reactivity between diagnostic reagents and microorganisms
WO1995032414A1 (en) * 1994-05-20 1995-11-30 Chemtrak, Inc. Qualitative surface immunoassay using consecutive reagent application
US6653066B1 (en) 1994-06-17 2003-11-25 Trinity Biotech Device and method for detecting polyvalent substances
EP0699906B1 (de) 1994-07-25 2002-04-24 Roche Diagnostics GmbH Verfahren zum Nachweis der Kontamination einer Oberfläche mit einem Analyten
US6818199B1 (en) * 1994-07-29 2004-11-16 James F. Hainfeld Media and methods for enhanced medical imaging
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US5521102A (en) * 1994-08-08 1996-05-28 Quidel Corporation Controlled sensitivity immunochromatographic assay
DE4443386C2 (de) * 1994-12-06 1996-09-19 Seratec Ges Fuer Biotechnologi Vorrichtung zur Durchführung eines Schwangerschaftstests
SE9500184D0 (sv) * 1995-01-20 1995-01-20 Pharmacia Ab Analysmetod som utnyttjar biospecifika affinitetsreaktioner och märkt reaktant samt reagens att användas i föredragen utförandeform
US5569608A (en) * 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
WO1996027129A1 (en) * 1995-02-28 1996-09-06 Ehrenkranz Joel R L Rapid, self-performing tsh immunoassay
US6309671B1 (en) 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US5804452A (en) * 1995-04-27 1998-09-08 Quidel Corporation One step urine creatinine assays
US20010051350A1 (en) * 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
ES2169185T3 (es) * 1995-09-08 2002-07-01 Fujirebio Kk Dispositivo de inmunoanalisis y metodo de inmunoanalisis empleando dicho dispositivo.
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
WO1997034150A1 (en) * 1996-03-14 1997-09-18 Abbott Laboratories Binding members extending from particles for immunoassay
US5876944A (en) * 1996-06-10 1999-03-02 Bayer Corporation Method for amplification of the response signal in a sandwich immunoassay
US5871905A (en) * 1996-09-04 1999-02-16 Epitope, Inc. Reduction of false positives in oral-fluid based immunoassays
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US6979576B1 (en) * 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
WO1998044158A1 (en) 1997-03-28 1998-10-08 Epitope, Inc. Simultaneous collection of dna and non-nucleic analytes from oral fluids
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
IT1292163B1 (it) * 1997-06-13 1999-01-25 Giorgio Torelli Dispositivo immunocromatografico a fissazione dell'analita
US5895765A (en) * 1997-06-30 1999-04-20 Bayer Corporation Method for the detection of an analyte by immunochromatography
DE69840657D1 (de) * 1997-07-16 2009-04-23 Charm Sciences Inc Verfahren zum Nachweis eines Restanalyts in einer Probe
EP1701164B1 (de) * 1997-07-16 2009-03-11 Charm Sciences Inc. Verfahren zum Nachweis eines Restanalyts in einer Probe
US6037186A (en) * 1997-07-16 2000-03-14 Stimpson; Don Parallel production of high density arrays
US5985675A (en) 1997-12-31 1999-11-16 Charm Sciences, Inc. Test device for detection of an analyte
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
US5922533A (en) * 1997-08-15 1999-07-13 Abbott Laboratories Rapid assay for simultaneous detection and differentiation of antibodies to HIV groups
US6824985B1 (en) * 1997-09-09 2004-11-30 Bayer Corporation Formulation for reducing urea effect for immunochromatography assays using urine samples
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US6004525A (en) * 1997-10-06 1999-12-21 Kabushiki Kaisha Toyota Chuo Kenkyusho Hollow oxide particle and process for producing the same
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6406692B1 (en) 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US20020136712A1 (en) * 1997-10-31 2002-09-26 Fischetti Vincent Bacterial phage associated lysing enzymes for the prophylactic and therapeutic treatment of colonization and infections caused by streptococcus pneumoniae
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US6277399B1 (en) * 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US20030129147A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
SE9704933D0 (sv) 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Metod som utnyttjar en ny kalibrator och test kit som innehåller kalibratorn
SE9704935D0 (sv) 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Analysmetod med partiklar
US6673629B2 (en) 1998-01-15 2004-01-06 Abbott Laboratories Neutralization of polycations in a chromatographic device for whole blood use
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
DK1696236T3 (da) * 1998-03-30 2014-08-18 Orasure Technologies Inc Opsamlingsindretning til analyse af mundvæsker
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6368873B1 (en) * 1998-04-09 2002-04-09 Applied Biotech, Inc. Identification of human urine for drug testing
US7220596B2 (en) * 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
USD434153S (en) * 1998-04-20 2000-11-21 Adeza Biomedical Corporation Point of care analyte detector system
USD432244S (en) * 1998-04-20 2000-10-17 Adeza Biomedical Corporation Device for encasing an assay test strip
SE9801563D0 (sv) 1998-04-30 1998-04-30 Pharmacia & Upjohn Diag Ab Förfarande med separation och kit att användas vid förfarandet
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
EP1086375A4 (de) * 1998-06-12 2004-12-15 New Horizons Diagnostics Inc Kolloidaler kolorimetrischer durchfluss- und lateralfluss-assay mit löslichen submikronpartikeln
AU8662598A (en) * 1998-07-22 2000-02-14 Syntron Bioresearch, Inc. Multiple analyte assay device
MXPA01001384A (es) 1998-08-06 2002-11-29 Spectral Diagnostics Inc Dispositivo y metodo para prueba analitica.
US6214629B1 (en) 1998-08-06 2001-04-10 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6171870B1 (en) 1998-08-06 2001-01-09 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6410341B1 (en) 1998-08-06 2002-06-25 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
CN1214816C (zh) * 1998-09-18 2005-08-17 比南股份有限公司 使用纯化的抗原特异性抗体快速检测肺炎链球菌的体外方法和材料
GB9823397D0 (en) * 1998-10-27 1998-12-23 Rsr Ltd Assays for thyroid autoantibodies
US6136610A (en) 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
US6566051B1 (en) * 1999-01-15 2003-05-20 Medtox Scientific, Inc. Lateral flow test strip
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
JP4212189B2 (ja) * 1999-07-12 2009-01-21 富士フイルム株式会社 乾式分析方法及び乾式分析要素
US6699507B1 (en) 1999-08-05 2004-03-02 Wisconsin Alulmni Research Foundation Colloidal particles of different element composition for specific labeling purposes
US20020127215A1 (en) * 1999-09-14 2002-09-12 Lawrence Loomis Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US20020004246A1 (en) * 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
US6365417B1 (en) 2000-02-09 2002-04-02 A-Fem Medical Corporation Collection device for lateral flow chromatography
US6998273B1 (en) 2000-02-09 2006-02-14 A-Fem Medical Corporation Collection device for lateral flow chromatography
EP1294749A2 (de) * 2000-03-09 2003-03-26 Heska Corporation Rekombinanten antigenen zur bestimmung des immun-zustandes eines tieres
US6607922B2 (en) 2000-03-17 2003-08-19 Quantum Design, Inc. Immunochromatographic assay method and apparatus
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US6656745B1 (en) 2000-06-02 2003-12-02 Francis X. Cole Devices and methods for a multi-level, semi-quantitative immunodiffusion assay
CU22968A1 (es) * 2000-06-07 2004-07-14 Ct Ingenieria Genetica Biotech Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
ATE349011T1 (de) 2000-10-03 2007-01-15 Minerva Biotechnologies Corp Magnetisches in situ dilutionsverfahren
US6764825B1 (en) * 2000-10-13 2004-07-20 Tang J. Wang Methods and device for detecting prostate specific antigen (PSA)
EP1333854A4 (de) * 2000-11-02 2005-10-05 New Horizons Diagnostics Corp Verwendung von bacteriellen phagen in verbindung mit lyseenzymen zur vorbeugung von nahrungsmittelvergiftungen
US7867756B2 (en) 2001-04-12 2011-01-11 Arkray, Inc. Specimen analyzing implement
WO2002100444A1 (en) * 2001-06-08 2002-12-19 Biosphere Medical Inc. Colloidal metal labelled microparticles, their production and use
US20040213765A1 (en) * 2001-07-13 2004-10-28 Vincent Fischetti Use of bacterial phage associated lytic enzymes to prevent food poisoning
US7790439B2 (en) 2001-08-09 2010-09-07 Panasonic Corporation Biosensor and measurement method
US20030059951A1 (en) * 2001-08-14 2003-03-27 Frushour Susan L.M. Maternal status testing in animals
US8481334B1 (en) 2001-11-06 2013-07-09 Charm Sciences, Inc. Method of attaching a ligand to a solid support
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US6703216B2 (en) 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
US20040018576A1 (en) * 2002-07-24 2004-01-29 Dematteo Todd M. Bence Jones protein testing cassette
DE60332248D1 (de) 2002-08-13 2010-06-02 N Dia Inc Vorrichtungen und verfahren zum nachweis von fruchtwasser in vaginalsekreten
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US20040092036A1 (en) * 2002-09-11 2004-05-13 Lattec I/S Device for analysing analyte compounds and use hereof
ES2525318T3 (es) * 2002-10-11 2014-12-22 Zbx Corporation Dispositivos de diagnóstico
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
WO2004048936A2 (en) * 2002-11-26 2004-06-10 University Of Utah Research Foundation Microporous materials, methods, and articles for localizing and quantifying analytes
US7597936B2 (en) * 2002-11-26 2009-10-06 University Of Utah Research Foundation Method of producing a pigmented composite microporous material
US20040121334A1 (en) * 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7197169B2 (en) * 2003-01-02 2007-03-27 Kuo-Jeng Wang Method for detecting a response of each probe zone on a test strip
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
GB0301225D0 (en) * 2003-01-20 2003-02-19 Univ Sunderland Surface layer immuno-chromatography
FI118904B (fi) * 2003-03-28 2008-04-30 Ani Biotech Oy Monikanavainen testiväline, menetelmä sen valmistamiseksi ja sen käyttö
GB0312403D0 (en) * 2003-05-29 2003-07-02 Axis Shield Asa Assay
AU2003270759A1 (en) * 2003-08-04 2005-03-07 Emory University Porous materials embedded with nanospecies
CA2477991C (en) * 2003-08-20 2014-04-08 Seikagaku Corporation Stabilizing agent and blocking agent
US7722817B2 (en) * 2003-08-28 2010-05-25 Epocal Inc. Lateral flow diagnostic devices with instrument controlled fluidics
US7238538B2 (en) * 2003-09-19 2007-07-03 Freitag Helmut E Chromatographic assay device and methods
JP4933258B2 (ja) 2003-09-22 2012-05-16 クイデル コーポレーション 試料中の複数分析物の検出装置
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7410808B1 (en) 2003-12-08 2008-08-12 Charm Sciences, Inc. Method and assay for detection of residues
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
EP1733235A1 (de) * 2004-01-29 2006-12-20 DSM IP Assets B.V. Verbesserter seitenstrom-bindungstest
DE602005016527D1 (de) * 2004-02-09 2009-10-22 Rapid Pathogen Screening Inc Verfahren zur schnelldiagnose von zielen in menschlichen körperflüssigkeiten
WO2005078442A1 (en) * 2004-02-10 2005-08-25 Dantini Daniel C Comprehensive food allergy test
FI20040205A (fi) 2004-02-11 2005-08-12 Reagena Ltd Oy Menetelmä ja laite pikatestin valmistamiseksi
US20050191704A1 (en) * 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
WO2005095967A1 (en) * 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
CN100357738C (zh) * 2004-03-26 2007-12-26 博奥生物有限公司 一种检测小分子化合物的方法
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
US20060024725A1 (en) 2004-07-30 2006-02-02 Robert Hussa Oncofetal fibronectin as a marker for pregnancy-related indications
US20060040258A1 (en) * 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
US20060046310A1 (en) * 2004-08-25 2006-03-02 Zong-Li Xia Amplification method for solid phase immunoassays
EP1799100A2 (de) * 2004-09-10 2007-06-27 Allan D. Pronovost Speichel-glucose-überwachung
US7465587B2 (en) * 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
US20060154260A1 (en) * 2005-01-07 2006-07-13 Barbour William M Sample preparation methods for diagnostic analyses
EP1843850B1 (de) 2005-01-31 2015-11-18 Realbio Technologies Ltd. Querstromkapillarvorrichtung mit mehrstufiger reaktion
US8614101B2 (en) * 2008-05-20 2013-12-24 Rapid Pathogen Screening, Inc. In situ lysis of cells in lateral flow immunoassays
US8445293B2 (en) * 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
US8669052B2 (en) * 2008-06-10 2014-03-11 Rapid Pathogen Screening, Inc. Lateral flow nucleic acid detector
EP1848999A4 (de) * 2005-02-16 2012-05-30 Gao Ping Epitope Diagnostics Testvorrichtung für stuhlproben und verwendungsverfahren dafür
US20060205090A1 (en) * 2005-03-14 2006-09-14 Newton Michael W Water-soluble conjugates for electrochemical detection
WO2006105111A2 (en) * 2005-03-29 2006-10-05 Inverness Medical Switzerland Gmbh Colloidal metal conjugates
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
PT2645106T (pt) 2005-04-04 2017-09-18 Biogen Ma Inc Método para avaliar uma resposta imune a um agente terapêutico
US7439079B2 (en) 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
WO2006119203A2 (en) * 2005-04-29 2006-11-09 Beckman Coulter Fluorescence lateral flow immunoassay
US7858384B2 (en) * 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7803319B2 (en) * 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US20070042427A1 (en) * 2005-05-03 2007-02-22 Micronics, Inc. Microfluidic laminar flow detection strip
EP1891447B1 (de) * 2005-05-23 2011-07-06 Phadia AB Verfahren und vorrichtungen für lateralfluss-tests mit zwei schritten
CA2612450C (en) 2005-06-28 2014-04-29 Zbx Corporation Membrane array and analytical device
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
US8003399B2 (en) * 2005-08-31 2011-08-23 Kimberly-Clark Worldwide, Inc. Nitrite detection technique
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
US7910381B2 (en) * 2005-10-13 2011-03-22 BioAssay Works Immuno gold lateral flow assay
US7344893B2 (en) * 2005-10-13 2008-03-18 Auric Enterprises, Llc Immuno-gold lateral flow assay
US8153444B2 (en) * 2005-10-13 2012-04-10 Auric Enterprises, Llc Immuno gold lateral flow assay
JP2007139649A (ja) * 2005-11-21 2007-06-07 Asahi Kasei Corp 分析装置の多孔体
US7279136B2 (en) * 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7618810B2 (en) * 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7871568B2 (en) * 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) * 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US20070202561A1 (en) * 2006-02-10 2007-08-30 Becton Dickinson And Company Electronic Detection Immunoassays that Utilize a Binder Support Medium
CA2659773A1 (en) * 2006-02-21 2007-08-30 Nanogen, Inc. Methods and compositions for analyte detection
EP3620469A1 (de) 2006-02-28 2020-03-11 Biogen MA Inc. Verfahren zur behandlung von entzündungs- und autoimmunerkrankungen mit natalizumab
CN101437541A (zh) 2006-03-03 2009-05-20 伊兰药品公司 用那他珠单抗治疗炎性疾病和自身免疫病的方法
WO2007106579A2 (en) * 2006-03-15 2007-09-20 Micronics, Inc. Integrated nucleic acid assays
US7547557B2 (en) * 2006-06-13 2009-06-16 Quantum Design, Inc. Directed-flow assay device
US20080014657A1 (en) * 2006-07-12 2008-01-17 Beckton Dickinson And Company Use of Albumin, Bovine, P-Aminophenyl N-Acetyl B-D Glucosaminide as a Control Line for an Immunoassay Device
NZ574759A (en) 2006-07-14 2010-10-29 Chemocentryx Inc Triazolyl phenyl benzenesulfonamides
US20110184747A1 (en) * 2006-08-09 2011-07-28 Carmen Bozic Method for distribution of a drug
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
EP2067045B1 (de) 2006-09-28 2020-08-05 The Macfarlane Burnet Institute for Medical Research and Public Health Limited Verfahren zur bestimmung der anzahl an cd4+ t-zellen und kit dafür
US7749775B2 (en) * 2006-10-03 2010-07-06 Jonathan Scott Maher Immunoassay test device and method of use
JP2008139297A (ja) * 2006-11-08 2008-06-19 Fujifilm Corp イムノクロマトグラフキット
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
US8012761B2 (en) * 2006-12-14 2011-09-06 Kimberly-Clark Worldwide, Inc. Detection of formaldehyde in urine samples
US8377379B2 (en) * 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
US7846383B2 (en) * 2006-12-15 2010-12-07 Kimberly-Clark Worldwide, Inc. Lateral flow assay device and absorbent article containing same
US7935538B2 (en) * 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
WO2009014787A2 (en) 2007-04-30 2009-01-29 Nanogen, Inc. Multianalyte assay
WO2009005552A2 (en) * 2007-03-29 2009-01-08 Epitype Corporation Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
EP2174957B1 (de) 2007-06-15 2016-03-16 Xiamen University An das hämagglutinin vom avian influenza virus subtype h5 bindende monoklonale antikörper und anwendungen davon
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
BRPI0813695B8 (pt) 2007-07-12 2021-05-25 Chemocentryx Inc compostos de heteroaril piridil e fenil benzenossulfonamidas fundidas, composição, método de modular a função de ccr2, usos dos compostos e forma cristalina
WO2009075894A1 (en) * 2007-12-13 2009-06-18 Beckman Coulter, Inc Device and methods for detecting a target cell
US20130196310A1 (en) 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
US8962260B2 (en) 2008-05-20 2015-02-24 Rapid Pathogen Screening, Inc. Method and device for combined detection of viral and bacterial infections
US8815609B2 (en) 2008-05-20 2014-08-26 Rapid Pathogen Screening, Inc. Multiplanar lateral flow assay with diverting zone
US9797898B2 (en) 2008-05-20 2017-10-24 Rapid Pathogen Screening, Inc. Methods and devices for using mucolytic agents including N-acetyl cysteine (NAC)
US9068981B2 (en) 2009-12-04 2015-06-30 Rapid Pathogen Screening, Inc. Lateral flow assays with time delayed components
US8609433B2 (en) 2009-12-04 2013-12-17 Rapid Pathogen Screening, Inc. Multiplanar lateral flow assay with sample compressor
US20110086359A1 (en) * 2008-06-10 2011-04-14 Rapid Pathogen Screening, Inc. Lateral flow assays
CN102076415B (zh) 2008-06-29 2015-06-24 瑞尔比奥技术有限公司 尤其可用作生物测定过程中的捕捉装置的液体转移装置
WO2010011860A1 (en) * 2008-07-23 2010-01-28 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US9234889B1 (en) 2008-12-18 2016-01-12 Charm Sciences, Inc. Method and test strip for detecting residues
JP5746978B2 (ja) 2009-01-30 2015-07-08 マイカーティス エヌ．ヴェ．ＭｙＣａｒｔｉｓ ＮＶ 急性心不全の診断、予知及び／又は予後用バイオマーカー及びその使用
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
US8168396B2 (en) 2009-05-11 2012-05-01 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US20100290948A1 (en) * 2009-05-15 2010-11-18 Xuedong Song Absorbent articles capable of indicating the presence of urinary tract infections
JP5414424B2 (ja) * 2009-08-31 2014-02-12 シスメックス株式会社 目的物質の検出方法、及び目的物質を検出するためのクロマトグラフィー用試験キット
AU2010303156B2 (en) 2009-10-11 2016-02-04 Biogen Ma Inc. Anti-VLA-4 related assays
NO2491401T3 (de) 2009-10-21 2018-11-03
EP2503337B1 (de) 2009-11-17 2016-08-24 Asahi Kasei Kabushiki Kaisha Organische gefärbte mikropartikel und diagnosereagenzienkit damit
HRP20221390T1 (hr) 2010-01-11 2023-01-06 Biogen Ma Inc. Analiza za antitijela jc virusa
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
KR101851117B1 (ko) 2010-01-29 2018-04-23 마이크로닉스 인코포레이티드. 샘플-투-앤서 마이크로유체 카트리지
US10706955B2 (en) 2010-03-23 2020-07-07 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
JP6092092B2 (ja) 2010-03-26 2017-03-08 マイカーティス エヌ．ヴェ．ＭｙＣａｒｔｉｓ ＮＶ 腎機能障害、糸球体濾過速度、呼吸困難、急性心不全、左心室肥大、心線維症、子癇前症、妊娠関連蛋白尿のバイオマーカーとしてのｌｔｂｐ２
WO2011127412A2 (en) 2010-04-09 2011-10-13 Critical Care Diagnostics, Inc. Soluble human st-2 antibodies and assays
WO2011128357A2 (en) 2010-04-13 2011-10-20 Pronota N.V. Biomarkers for hypertensive disorders of pregnancy
ES2945032T3 (es) 2010-05-06 2023-06-28 Charm Sciences Inc Dispositivo de incubadora con lector
CN103025885B (zh) 2010-05-26 2016-01-20 伊利诺伊大学评议会 用于检测和定量宽范围分析物的个人葡萄糖计
EP2591366A2 (de) 2010-07-08 2013-05-15 Pronota NV Quiescin q6 als biomarker für hypertonie während der schwangerschaft
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US8828329B2 (en) 2010-10-01 2014-09-09 Church & Dwight, Co., Inc. Electronic analyte assaying device
WO2012076553A2 (en) 2010-12-06 2012-06-14 Pronota N.V. Biomarkers and parameters for hypertensive disorders of pregnancy
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
CA2832494C (en) 2011-04-06 2019-11-26 Ortho-Clinical Diagnostics, Inc. Assay device having rhombus-shaped projections
EP2771349B1 (de) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatikverfahren zur bestimmung von peptidbindungen
CA2846247A1 (en) 2011-09-16 2013-03-21 Credo Biomedical Pte Ltd Molecular diagnostic assay device and method of use
US20130116597A1 (en) * 2011-11-04 2013-05-09 Phenomenex, Inc. Method and apparatus for acquiring blood for testing
US20150045245A1 (en) 2011-12-08 2015-02-12 Biocartis Nv Biomarkers and test panels useful in systemic inflammatory conditions
CN104136924B (zh) 2011-12-15 2018-05-29 麦卡蒂斯股份有限公司 用于先兆子痫的生物标志物和参数
EP2794107B1 (de) 2011-12-22 2021-08-11 Life Technologies Corporation Sequenzielle lateralfluss-kapillarvorrichtung zur analytbestimmung
US20130171619A1 (en) 2011-12-30 2013-07-04 General Electric Company Porous membranes having a hydrophilic coating and methods for their preparation and use
CA2802260C (en) 2012-01-20 2021-03-30 Ortho-Clinical Diagnostics, Inc. Controlling fluid flow through an assay device
KR20130085992A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 제어가능한 샘플 크기를 갖는 분석 장치
JP6177529B2 (ja) 2012-01-20 2017-08-09 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． 多数の試薬セルを有するアッセイ装置
BR102013001328A2 (pt) 2012-01-20 2015-05-12 Ortho Clinical Diagnostics Inc Dispositivo de ensino tendo fluxo uniforme próximo de cantos
WO2013109821A1 (en) 2012-01-20 2013-07-25 Ortho-Clinical Diagnostics, Inc. Assay device having multiplexing
EP2807271B1 (de) 2012-01-24 2018-08-22 CD Diagnostics, Inc. System zum nachweis einer infektion in der synovialflüssigkeit
WO2013116333A2 (en) 2012-01-31 2013-08-08 Regents Of University Of Minnesota Thermal contrast assay and reader
US10816492B2 (en) 2012-01-31 2020-10-27 Regents Of The University Of Minnesota Lateral flow assays with thermal contrast readers
US10725033B2 (en) 2012-01-31 2020-07-28 Regents Of The University Of Minnesota Lateral flow assays with thermal contrast readers
EP2812704A4 (de) 2012-02-07 2016-03-23 Intuitive Biosciences Inc Mycobakteriumstuberkulose-spezifische peptide zur erkennung einer infektion oder immunisierung nichtmenschlicher primaten
AU2013225938B2 (en) 2012-02-29 2017-08-10 Chemocentryx, Inc. Pyrazol-1-yl benzene sulfonamides as CCR9 antagonists
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
WO2014005138A1 (en) * 2012-06-29 2014-01-03 Kerschensteiner Daniel A Colorimetric gelatinase assay
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
WO2014025415A2 (en) 2012-08-08 2014-02-13 Scanadu Incorporated Method and apparatus for performing and quantifying color changes induced by specific concentrations of biological analytes in an automatically calibrated environment
US9528941B2 (en) 2012-08-08 2016-12-27 Scanadu Incorporated Method and apparatus for determining analyte concentration by quantifying and interpreting color information captured in a continuous or periodic manner
US9285323B2 (en) 2012-08-08 2016-03-15 Scanadu Incorporated Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions
PL2888373T3 (pl) 2012-08-21 2018-08-31 Janssen Pharmaceutica Nv Przeciwciała dla arypiprazolu i ich zastosowanie
EP2887952B1 (de) 2012-08-21 2019-05-15 Janssen Pharmaceutica NV Antikörper gegen olanzapinhaptene und verwendung davon
AU2013305907B2 (en) 2012-08-21 2018-01-18 Saladax Biomedical Inc. Antibodies to quetiapine and use thereof
PL2888590T3 (pl) 2012-08-21 2020-11-30 Janssen Pharmaceutica Nv Przeciwciała dla olanzapiny i ich zastosowanie
EP2888286B1 (de) 2012-08-21 2018-02-21 Janssen Pharmaceutica NV Antikörper gegen quetiapinhaptene und verwendung davon
EP2888285B1 (de) 2012-08-21 2024-04-17 Janssen Pharmaceutica NV Antikörper gegen aripiprazol-haptene und verwendung davon
CA2882449C (en) 2012-08-21 2018-09-04 Ronghui Lin Haptens of aripiprazole and their use in immunoassays
WO2014031645A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to risperidone haptens and use thereof
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
AU2013305965B2 (en) 2012-08-21 2017-08-24 Saladax Biomedical Inc. Antibodies to paliperidone and use thereof
AU2013305887B2 (en) 2012-08-21 2018-02-22 Saladax Biomedical Inc. Antibodies to risperidone and use thereof
US20140072959A1 (en) 2012-09-12 2014-03-13 Force Diagnostics, Inc. Rapid tests for insurance underwriting
CN104823051A (zh) * 2012-10-05 2015-08-05 韦拉克斯生物医学股份有限公司 多分析物试验
JP6328655B2 (ja) 2012-11-15 2018-05-23 オーソ・クリニカル・ダイアグノスティックス・インコーポレーテッド 反応時間を使用してアッセイを較正すること
US9360479B2 (en) 2012-11-15 2016-06-07 Daniel Wang Rapid lateral flow assay method for low quantity liquid or dry samples
RU2013150854A (ru) 2012-11-15 2015-05-20 Орто-Клиникал Дайэгностикс, Инк. Контроль качества/работы устройства латерального проточного анализа на основании мониторинга потока
WO2014087255A2 (en) 2012-11-21 2014-06-12 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
WO2014100725A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
EP2935908B1 (de) 2012-12-21 2019-08-14 PerkinElmer Health Sciences, Inc. Fluidkreisläufe und zugehörige herstellungsverfahren
WO2014100743A2 (en) 2012-12-21 2014-06-26 Micronics, Inc. Low elasticity films for microfluidic use
CA2897053C (en) 2013-01-02 2020-10-13 N-Dia, Inc. Methods for predicting time-to-delivery in pregnant women
US8968677B2 (en) 2013-01-22 2015-03-03 Quantum Design International, Inc. Frazil ice conjugate assay device and method
CA2841692C (en) 2013-02-12 2023-08-22 Zhong Ding Reagent zone deposition pattern
CN105102980B (zh) 2013-02-26 2017-11-03 阿斯图特医药公司 具有试条保持件的横向流动测定法
US9599615B2 (en) 2013-03-13 2017-03-21 Symbolics, Llc Lateral flow assays using two dimensional test and control signal readout patterns
EP2778679B1 (de) 2013-03-15 2017-09-27 Ortho-Clinical Diagnostics, Inc. Drehbare scheibenförmige Flüssigkeitsprobenentnahmevorrichtung
EP2777499B1 (de) 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Drehbare Vorrichtung zur Flüssigkeitsprobenentnahme
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
US10119976B2 (en) 2013-05-28 2018-11-06 Biogen Ma Inc. Method of assessing risk of PML
US10364451B2 (en) 2013-05-30 2019-07-30 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US10392611B2 (en) 2013-05-30 2019-08-27 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
CA2932269C (en) 2013-12-06 2022-01-25 Ortho Clinical Diagnostics, Inc. Assay device having a wash port
JP6481192B2 (ja) * 2013-12-27 2019-03-13 地方独立行政法人大阪健康安全基盤研究所 クドア・セプテンプンクタータの迅速検出法
US10416158B2 (en) 2014-03-11 2019-09-17 Wisconsin Alumni Research Foundation Peptide MHCII tetramers to detect endogenous calnexin specific CD4 T cells
JP2016010338A (ja) * 2014-06-27 2016-01-21 国立大学法人東北大学 核酸検出用デバイス
US9903858B2 (en) 2014-07-23 2018-02-27 Ortho-Clinical Diagnostics, Inc. Multiplexing with single sample metering event to increase throughput
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
US10071373B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
US9863811B2 (en) 2014-08-15 2018-01-09 Scanadu Incorporated Precision luxmeter methods for digital cameras to quantify colors in uncontrolled lighting environments
WO2016057424A1 (en) 2014-10-06 2016-04-14 Chemocentryx, Inc. Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies
WO2016154530A1 (en) 2015-03-26 2016-09-29 Duke University Targeted therapeutic agents comprising multivalent protein-biopolymer fusions
CA2981297A1 (en) 2015-04-06 2016-10-13 Bludiagnostics, Inc. A test device for detecting an analyte in a saliva sample and method of use
EP3286216B1 (de) 2015-04-23 2022-06-08 Nevada Research & Innovation Corporation Pilznachweis mit mannan-epitop
JP6728237B2 (ja) 2015-05-19 2020-07-22 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． アッセイデバイス中の液体試料の流動を改善する方法
EP3331572A4 (de) 2015-08-04 2019-05-01 CD Diagnostics, Inc. Verfahren zur erkennung von unerwünschter lokaler gewebereaktionsnekrose
JP6882782B2 (ja) 2015-08-04 2021-06-02 デューク ユニバーシティ 遺伝子コードされた本質的に無秩序な送達用ステルスポリマーおよびその使用方法
CA2994209A1 (en) 2015-08-06 2017-02-09 Lia Diagnostics, Inc. Water dispersible assays
EP3340880A1 (de) * 2015-08-28 2018-07-04 POPS! Diabetes Care, Inc. System für blutzuckermanagement
US10808287B2 (en) 2015-10-23 2020-10-20 Rapid Pathogen Screening, Inc. Methods and devices for accurate diagnosis of infections
US20180321202A1 (en) 2015-11-06 2018-11-08 Oslo Universitetssykehus Hf Methods and devices for detecting methanol poisoning using formate oxidase
US20180364243A1 (en) 2015-12-09 2018-12-20 Intuitive Biosciences, Inc. Automated silver enhancement system
WO2017106508A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
EP3390449A1 (de) 2015-12-17 2018-10-24 Janssen Pharmaceutica N.V. Antikörper gegen risperidon und verwendung davon
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
US20200200735A9 (en) 2016-02-22 2020-06-25 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
WO2017178554A1 (en) 2016-04-13 2017-10-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
WO2018039047A1 (en) 2016-08-23 2018-03-01 Qoolabs, Inc. Lateral flow assay for assessing recombinant protein expression or reporter gene expression
CN109890833A (zh) 2016-09-14 2019-06-14 杜克大学 用于递送亲水性药物的基于三嵌段多肽的纳米粒子
KR20190064600A (ko) 2016-09-23 2019-06-10 듀크 유니버시티 Lcst 거동을 갖는 비구조화된 비-반복적 폴리펩티드
IL294410B2 (en) 2016-11-23 2024-02-01 Chemocentryx Inc A method for the treatment of focal segmental tuberous sclerosis
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
WO2018111331A1 (en) 2016-12-28 2018-06-21 Neogen Corporation Implement analyzing device and method for utilizing the same
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018152496A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions and methods for the diagnosis and treatment of zika virus infection
EP3615569A1 (de) 2017-04-25 2020-03-04 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Antikörper und verfahren zur diagnose und behandlung von epstein-barr-virus-infektionen
WO2018203145A1 (en) 2017-05-03 2018-11-08 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
WO2018213320A1 (en) 2017-05-15 2018-11-22 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
JP7273721B2 (ja) 2017-05-19 2023-05-15 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 対象の喫煙ステータスを区別するための診断テスト
WO2019006374A1 (en) 2017-06-30 2019-01-03 Duke University ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS
CN111094334A (zh) 2017-07-19 2020-05-01 美国卫生与公众服务部 用于诊断和治疗乙肝病毒感染的抗体和方法
AU2018347361A1 (en) 2017-10-11 2020-04-30 Chemocentryx, Inc. Treatment of focal segmental glomerulosclerosis with CCR2 antagonists
WO2019213416A1 (en) 2018-05-02 2019-11-07 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
RU2682320C1 (ru) * 2018-05-07 2019-03-19 Владислав Николаевич Ласкавый Средство для профилактики вирусных инфекций
US20210199649A1 (en) * 2018-05-17 2021-07-01 Techno Medica Co., Ltd. Competitive immunochromatographic analysis method and immunochromatographic sensor
JP6530114B1 (ja) * 2018-06-27 2019-06-12 株式会社ニチレイバイオサイエンス メンブランシートのブロッキング方法
WO2020014353A1 (en) 2018-07-11 2020-01-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (ftc, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
EP3829622A4 (de) 2018-08-02 2022-05-11 Duke University Doppel-agonisten-fusionsproteine
US11293839B2 (en) 2018-08-16 2022-04-05 Epitope Biotechnology Co., Ltd. Device for fecal sample collection and extraction
EP3870205A4 (de) 2018-10-24 2022-07-13 OraSure Technologies, Inc. Lateral-flow-assays für differenzielle isotypendetektion
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
JP2020003477A (ja) * 2019-05-09 2020-01-09 株式会社ニチレイバイオサイエンス メンブランシートのブロッキング方法
WO2020245653A1 (en) 2019-06-04 2020-12-10 Alere Toxicology Plc Fluid specimen testing
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
CN110824177B (zh) * 2019-09-11 2021-06-11 润和生物医药科技(汕头)有限公司 一种快速检测试纸及其制备方法和应用
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
TW202203916A (zh) 2020-03-31 2022-02-01 美商卡默森屈有限公司 使用ｃｃｒ９抑制劑及抗ｉｌ—２３阻斷抗體治療發炎性腸道疾病的組成物及方法
WO2022027037A1 (en) 2020-07-27 2022-02-03 Single Cell Technology, Inc. Anti-sars corona virus-2 spike protein antibodies
CN117677639A (zh) 2021-08-18 2024-03-08 菲利普莫里斯生产公司 抗体及其抗原结合片段
WO2023163155A1 (ja) * 2022-02-28 2023-08-31 株式会社カネカ 検出用デバイス
WO2023239834A1 (en) * 2022-06-08 2023-12-14 Spotitearly Ltd. Machine learning (ml)-based disease-detection system using detection animals
WO2024030982A2 (en) 2022-08-02 2024-02-08 Diadem Spa Device for detection and prognostic assessment of neurodegenerative disorders

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941618A (de) * 1972-08-29 1974-04-19
US4022876A (en) * 1973-06-21 1977-05-10 Stanford Research Institute Mass spectrometric immunoassay
US4166105A (en) * 1973-07-30 1979-08-28 Block Engineering, Inc. Dye tagged reagent
CA1039649A (en) * 1973-08-30 1978-10-03 General Electric Company Method of forming multilayer immunologically complexed films
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
IT1087285B (it) * 1976-11-10 1985-06-04 Hoffmann La Roche Procedimento di determinazione immunologico
US4407943A (en) * 1976-12-16 1983-10-04 Millipore Corporation Immobilized antibody or antigen for immunoassay
US4200690A (en) * 1976-12-16 1980-04-29 Millipore Corporation Immunoassay with membrane immobilized antibody
US4122030A (en) * 1977-09-19 1978-10-24 Xerox Corporation Formation of colloidal dispersions of selenium by the locus control method
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
US4235601A (en) * 1979-01-12 1980-11-25 Thyroid Diagnostics, Inc. Test device and method for its use
US4361537A (en) * 1979-01-12 1982-11-30 Thyroid Diagnostics, Inc. Test device and method for its use
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4452901A (en) * 1980-03-20 1984-06-05 Ciba-Geigy Corporation Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
FI76888C (fi) * 1981-04-29 1988-12-12 Ciba Geigy Ag Nya medel och foerpackningar foer immunologiska analyser.
DE3130924A1 (de) * 1981-08-05 1983-02-17 Röhm GmbH, 6100 Darmstadt Oberflaechenreiche systeme zur fixierung von nucleophile gruppen enthaltenden substraten
US4452886A (en) 1981-09-21 1984-06-05 Henry Robert P Novel photon absorbing or emitting polymers and their use as reagents in immunoassay systems
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
JPS59122950A (ja) * 1982-12-28 1984-07-16 Toray Ind Inc 生物学的に活性な物質の測定法およびそれに使用する標識剤
US4552839A (en) 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
GB8331514D0 (en) * 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
US4703017C1 (en) * 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US4756828A (en) 1984-04-12 1988-07-12 Syntex (U.S.A.) Inc. Chromatographic strip having non-compressed edges
JPS60231167A (ja) * 1984-05-01 1985-11-16 Nitsusui Seiyaku Kk 診断用スクリ−ニング試薬及びその調製法
FR2571146B1 (fr) * 1984-10-01 1988-02-26 Centre Nat Rech Scient Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
DE3586951T2 (de) † 1984-12-20 1993-04-29 Nycomed Pharma As Festphasendiffusionstextverfahren.
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
JPS61224986A (ja) * 1985-03-28 1986-10-06 Eisai Co Ltd エラスタ−ゼ含有凍結乾燥物
GB8526741D0 (en) * 1985-10-30 1985-12-04 Boots Celltech Diagnostics Binding assay device
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
US4960692A (en) * 1986-03-18 1990-10-02 Fisher Scientific Company Assay employing binding pair members on particles and on a filter or membrane
AU602694B2 (en) * 1986-06-09 1990-10-25 Ortho Diagnostic Systems Inc. Improved colloidal gold membrane assay
US4818686A (en) * 1986-09-15 1989-04-04 Coulter Corporation Chemical blocking agent against non-specific binding or staining of an antibody specific for terminal deoxynucleotidyl transferase in biological specimens during immunoassay
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
US5310650A (en) * 1986-09-29 1994-05-10 Abbott Laboratoires Method and device for improved reaction kinetics in nucleic acid hybridizations
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US4748042A (en) * 1987-03-31 1988-05-31 V-Tech, Inc. Method and apparatus for imprinting membranes with patterns of antibody
DE3856421T2 (de) * 1987-04-27 2000-12-14 Unilever Nv Spezifische Bindungstestverfahren
DE3715485A1 (de) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Stabilisierung von ss-galactosidase
US4855240A (en) * 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US4943522A (en) * 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US4962023A (en) * 1987-06-22 1990-10-09 Louisiana State University, Agricultural And Mechanical College Single incubation immuno sorbent assay method using particle labels to detect test antigen specific antibodies in presence of other antibodies
US4954452A (en) * 1987-07-09 1990-09-04 Abbott Laboratories Non-metal colloidal particle immunoassay
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4859604A (en) * 1987-08-27 1989-08-22 Ampor, Inc. Composition for stabilization of diagnostic reagents
US5529901A (en) * 1987-11-19 1996-06-25 Staat Der Nederlanden Method for determining the presence or amount of analyte using a stable colloidal carbon sol
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
US5281522A (en) * 1988-09-15 1994-01-25 Adeza Biomedical Corporation Reagents and kits for determination of fetal fibronectin in a vaginal sample
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5091318A (en) * 1990-04-13 1992-02-25 Abbott Laboratories Binding of allergens to a solid phase
US5266497A (en) * 1990-08-31 1993-11-30 Japan Synthetic Rubber Co., Ltd. Immunochromatographic assay with improved colored latex
US5451504A (en) * 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
US5310647A (en) * 1992-04-01 1994-05-10 Cherrystone Corporation Detection and measurement of destructive and polymer forming enzymes by colloidal flocculation
JPH0746107A (ja) * 1993-07-28 1995-02-14 Ricoh Co Ltd 出力切り替え回路
US5599668A (en) * 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
US5712172A (en) * 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use

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Publication number Publication date
CA1306675C (en) 1992-08-25
EP0675361A2 (de) 1995-10-04
US20010006821A1 (en) 2001-07-05
US6534320B2 (en) 2003-03-18
AU614294B2 (en) 1991-08-29
EP0299428A2 (de) 1989-01-18
ES2085257T5 (es) 2004-09-16
EP0299428B1 (de) 1996-01-31
US5120643A (en) 1992-06-09
EP0675361A3 (de) 1995-10-25
JPS6432169A (en) 1989-02-02
EP0299428B2 (de) 2004-01-02
ATE133788T1 (de) 1996-02-15
ES2085257T3 (es) 1996-06-01
AU1893388A (en) 1989-04-27
ES2186697T3 (es) 2003-05-16
DE3854951T2 (de) 1996-11-07
EP0675361B1 (de) 2002-11-06
EP0299428A3 (de) 1991-07-31
DE3854951T3 (de) 2004-09-02
ATE227427T1 (de) 2002-11-15
DE3856544D1 (de) 2002-12-12
JPH0760159B2 (ja) 1995-06-28
DE3856544T2 (de) 2003-08-21
US5578577A (en) 1996-11-26

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