DE3850340D1 - Zahlreiche kleine Pillen in flüssiger Darreichungsform. - Google Patents
Zahlreiche kleine Pillen in flüssiger Darreichungsform.Info
- Publication number
- DE3850340D1 DE3850340D1 DE3850340T DE3850340T DE3850340D1 DE 3850340 D1 DE3850340 D1 DE 3850340D1 DE 3850340 T DE3850340 T DE 3850340T DE 3850340 T DE3850340 T DE 3850340T DE 3850340 D1 DE3850340 D1 DE 3850340D1
- Authority
- DE
- Germany
- Prior art keywords
- dosage form
- liquid dosage
- numerous small
- delivery system
- small pills
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/112,189 US4853229A (en) | 1987-10-26 | 1987-10-26 | Method for adminstering tiny pills |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3850340D1 true DE3850340D1 (de) | 1994-07-28 |
DE3850340T2 DE3850340T2 (de) | 1994-10-27 |
Family
ID=22342549
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3850340T Expired - Fee Related DE3850340T2 (de) | 1987-10-26 | 1988-10-20 | Zahlreiche kleine Pillen in flüssiger Darreichungsform. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4853229A (de) |
EP (1) | EP0313992B1 (de) |
JP (1) | JP2840260B2 (de) |
KR (1) | KR950013749B1 (de) |
AT (1) | ATE107501T1 (de) |
AU (1) | AU623349B2 (de) |
CA (1) | CA1318825C (de) |
DE (1) | DE3850340T2 (de) |
DK (1) | DK595688A (de) |
ES (1) | ES2055727T3 (de) |
IE (1) | IE61942B1 (de) |
PT (1) | PT88854B (de) |
ZA (1) | ZA887976B (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5030454A (en) * | 1987-10-26 | 1991-07-09 | Alza Corporation | Method for delivering drug in tiny pills in liquid carrier |
YU120988A (en) * | 1988-06-23 | 1990-06-30 | Lek Tovarna Farmacevtskih | Process for preparing new dispersion pills of cimetidine |
NZ233975A (en) * | 1989-08-16 | 1992-06-25 | Sterling Drug Inc | Aspirin granules coated with a gastroprotectant |
EP0418596A3 (en) * | 1989-09-21 | 1991-10-23 | American Cyanamid Company | Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form |
WO1994018987A1 (en) * | 1993-02-19 | 1994-09-01 | Nippon Shinyaku Co., Ltd. | Drug composition containing nucleic acid copolymer |
TW360548B (en) | 1993-04-08 | 1999-06-11 | Powderject Res Ltd | Products for therapeutic use |
EP0622407A1 (de) * | 1993-04-28 | 1994-11-02 | Hoechst Celanese Corporation | Polymermischung aus Celluloseacetat und Stärkeacetat, die zur Formung von Fasern, Filmen und Kunststoffmaterialien verwendet wird; Verfahren zur Herstellung dieser Mischung |
US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
US6262115B1 (en) * | 1995-05-22 | 2001-07-17 | Alza Coporation | Method for the management of incontinence |
US5912268A (en) * | 1995-05-22 | 1999-06-15 | Alza Corporation | Dosage form and method for treating incontinence |
GB9609094D0 (en) * | 1996-05-01 | 1996-07-03 | Univ Strathclyde | Delivery device |
US6919373B1 (en) | 1996-11-12 | 2005-07-19 | Alza Corporation | Methods and devices for providing prolonged drug therapy |
US20040062799A1 (en) * | 1997-09-29 | 2004-04-01 | Ayer Atul D. | Therapeutic composition and delivery system for administering drug |
AUPP022297A0 (en) * | 1997-11-06 | 1997-11-27 | R.P. Scherer Holdings Pty Ltd | Vitamin coating |
US6551613B1 (en) * | 1998-09-08 | 2003-04-22 | Alza Corporation | Dosage form comprising therapeutic formulation |
US7674480B2 (en) * | 2000-06-23 | 2010-03-09 | Teva Pharmaceutical Industries Ltd. | Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition |
US6881420B2 (en) | 2000-06-23 | 2005-04-19 | Teva Pharmaceutical Industries Ltd. | Compositions and dosage forms for gastric delivery of irinotecan and methods of treatment that use it to inhibit cancer cell proliferation |
US6476006B2 (en) | 2000-06-23 | 2002-11-05 | Teva Pharmaceutical Industries, Ltd. | Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates |
FR2816507B1 (fr) * | 2000-11-16 | 2003-02-28 | Ethypharm Lab Prod Ethiques | Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules |
NZ567711A (en) * | 2001-06-11 | 2009-10-30 | Xenoport Inc | Orally administered dosage forms of GABA analog prodrugs having reduced toxicity |
US7232924B2 (en) * | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
AU2002345638A1 (en) * | 2001-06-11 | 2002-12-23 | Xenoport, Inc. | Amino acid conjugates providing for sustained systemic concentrations of gaba analogues |
EP1404297B1 (de) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoirvorrichtung für die intraokulare arzneimittelabgabe |
US20030158154A1 (en) * | 2001-07-17 | 2003-08-21 | Moshe Fleshner-Barak | Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate |
US8061006B2 (en) | 2001-07-26 | 2011-11-22 | Powderject Research Limited | Particle cassette, method and kit therefor |
AR039744A1 (es) * | 2002-06-26 | 2005-03-09 | Alza Corp | Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada |
US20050026871A1 (en) * | 2002-07-17 | 2005-02-03 | Moshe Flashner-Barak | Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative |
US20050208132A1 (en) * | 2002-07-29 | 2005-09-22 | Gayatri Sathyan | Methods and dosage forms for reducing side effects of benzisozazole derivatives |
WO2004010970A1 (en) * | 2002-07-29 | 2004-02-05 | Alza Corporation | Formulations and dosage forms for controlled delivery of topiramate |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
US7101912B2 (en) | 2002-12-06 | 2006-09-05 | Xenoport, Inc. | Carbidopa prodrugs and derivatives, and compositions and uses thereof |
WO2004053192A1 (en) * | 2002-12-11 | 2004-06-24 | Xenoport, Inc. | Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity |
CA2520468A1 (en) * | 2003-03-31 | 2004-10-21 | Xenoport, Inc. | Treating or preventing hot flashes using prodrugs of gaba analogs |
WO2005016306A2 (en) * | 2003-08-06 | 2005-02-24 | Alza Corporation | Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation |
PT1660440E (pt) * | 2003-08-20 | 2012-05-15 | Xenoport Inc | Pró-fármacos de aciloxialquilcarbamato, métodos de síntese e utilização |
EP2354120A1 (de) | 2003-08-20 | 2011-08-10 | XenoPort, Inc. | Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon |
EP1658048A2 (de) * | 2003-08-22 | 2006-05-24 | ALZA Corporation | Schrittweise abgabe von topiramat über einen längeren zeitraum |
WO2005020959A2 (en) * | 2003-09-02 | 2005-03-10 | Alza Corporation | Novel drug compositions and dosage forms of topiramate |
EP1670451A4 (de) * | 2003-09-11 | 2009-10-21 | Xenoport Inc | Behandlung und/oder prävention von harninkontinenz mit prodrugs von gaba-analoga |
EP1677812A4 (de) * | 2003-09-17 | 2010-03-24 | Xenoport Inc | Behandlung oder prävention des syndroms der ruhelosen beine mit prodrugs von gaba/analoga |
WO2005063206A1 (en) * | 2003-12-23 | 2005-07-14 | Alza Corporation | Methods and dosage forms for increasing solubility of drug compositions for controlled delivery |
WO2005065648A2 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation, Inc., | Novel drug compositions and dosage forms of topiramate |
US20050175696A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Drug granule coatings that impart smear resistance during mechanical compression |
EP1701706A2 (de) * | 2003-12-29 | 2006-09-20 | Alza Corporation | Neue arzneimittelzusammensetzungen und dosierformen |
US20060128676A1 (en) * | 2004-07-13 | 2006-06-15 | Pharmacofore, Inc. | Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain |
GB2419094A (en) * | 2004-10-12 | 2006-04-19 | Sandoz Ag | Pharmaceutical composition of unpleasnt tasing active substances |
WO2006050471A2 (en) * | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
US7494985B2 (en) * | 2004-11-03 | 2009-02-24 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use |
KR101228399B1 (ko) * | 2004-11-04 | 2013-01-31 | 제노포트 인코포레이티드 | 가바펜틴 프로드러그 서방성 경구 투여 형태 |
EP2338881A1 (de) | 2005-02-23 | 2011-06-29 | Prexa Pharmaceuticals, Inc. | Inhibitoren des Dopamintransporters zur Verwendung bei der Behandlung von Bewegungserkrankungen und anderen ZNS-Indikationen |
CN101253148B (zh) | 2005-06-20 | 2013-01-02 | 克塞诺波特公司 | 凝血酸的酰氧基烷基氨基甲酸酯前药,合成和使用的方法 |
US20070049626A1 (en) * | 2005-08-26 | 2007-03-01 | Tran Pierre V | Treating premature ejaculation using gabapentin and pregabalin prodrugs |
SG172633A1 (en) | 2006-05-26 | 2011-07-28 | Pharmacofore Inc | Controlled release of phenolic opioids |
US9744137B2 (en) * | 2006-08-31 | 2017-08-29 | Supernus Pharmaceuticals, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
US7585996B2 (en) * | 2006-09-15 | 2009-09-08 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
AU2007319141B2 (en) | 2006-11-17 | 2013-01-10 | Supernus Pharmaceuticals Inc. | Sustained-release formulations of topiramate |
EP2101752A1 (de) * | 2006-12-08 | 2009-09-23 | Xenoport, Inc. | Verwendung prodrugs von gaba-analoga zur behandlung von erkrankungen |
EP2298282B1 (de) * | 2008-05-15 | 2017-02-15 | Cocokara fine Healthcare Inc. | Kombination von arzneimitteln mit unterschiedlichen physikalischen eigenschaften in einer einzelnen dosierform |
PL2391419T3 (pl) | 2009-01-29 | 2019-12-31 | Forsight Vision4, Inc. | Dostarczanie leku do tylnego odcinka |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
WO2011028234A1 (en) * | 2009-09-04 | 2011-03-10 | Xenoport, Inc. | Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid |
US20110130711A1 (en) * | 2009-11-19 | 2011-06-02 | Follica, Inc. | Hair growth treatment |
US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
SI2600812T1 (sl) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Naprava za zdravljenje očesa |
EP3861969A1 (de) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injektorvorrichtung zur arzneimittelabgabe |
CN107050456B (zh) | 2010-09-28 | 2022-08-12 | 加利福尼亚大学董事会 | 治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合 |
CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
EP4249059A3 (de) | 2011-06-28 | 2023-11-29 | ForSight Vision4, Inc. | Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge |
SI2755600T1 (sl) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Naprava za izmenjavo tekočine |
AU2014236455B2 (en) | 2013-03-14 | 2018-07-12 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
EP4302736A3 (de) | 2013-03-28 | 2024-04-03 | ForSight Vision4, Inc. | Ophthalmisches implantat zur abgabe von therapeutischen substanzen |
MY182793A (en) | 2014-08-08 | 2021-02-05 | Forsight Vision4 Inc | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
US10500091B2 (en) | 2014-11-10 | 2019-12-10 | Forsight Vision4, Inc. | Expandable drug delivery devices and methods of use |
US10335406B2 (en) | 2015-10-01 | 2019-07-02 | Elysium Therapeutics, Inc. | Opioid compositions resistant to overdose and abuse |
CA2998708C (en) | 2015-10-01 | 2019-09-03 | Elysium Therapeutics, Inc. | Polysubunit opioid prodrugs resistant to overdose and abuse |
CN108430405B (zh) | 2015-11-20 | 2021-04-13 | 弗赛特影像4股份有限公司 | 用于缓释药物递送装置的多孔结构 |
US11617680B2 (en) | 2016-04-05 | 2023-04-04 | Forsight Vision4, Inc. | Implantable ocular drug delivery devices |
EP3595663A4 (de) | 2017-03-17 | 2021-01-13 | Elysium Therapeutics, Inc. | Mehrfachuntereinheit-opioid-prodrugs mit resistenz gegen überdosierung und missbrauch |
WO2019103906A1 (en) | 2017-11-21 | 2019-05-31 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA816052A (en) * | 1969-06-24 | Milosovich George | Medicinal colloid beads with rupturable plastic coating | |
US2738303A (en) * | 1952-07-18 | 1956-03-13 | Smith Kline French Lab | Sympathomimetic preparation |
US2793979A (en) * | 1953-03-30 | 1957-05-28 | Smith Kline French Lab | Method of making a sustained release pharmaceutical tablet and product of the method |
US2953497A (en) * | 1953-06-03 | 1960-09-20 | Howard A Press | Therapeutic tablets |
US2996431A (en) * | 1953-12-16 | 1961-08-15 | Barry Richard Henry | Friable tablet and process for manufacturing same |
US2921883A (en) * | 1957-05-03 | 1960-01-19 | Smith Kline French Lab | Novel coating material for medicaments |
US2897121A (en) * | 1957-06-04 | 1959-07-28 | Upjohn Co | Pharmaceutical composition |
GB931532A (en) * | 1958-12-22 | 1963-07-17 | Upjohn Co | Injectable preparations comprising encapsulated medicaments and processes for making them |
US2951792A (en) * | 1959-11-18 | 1960-09-06 | Smith Kline French Lab | Sustained release pharmaceutical tablets |
US3081233A (en) * | 1960-08-08 | 1963-03-12 | Upjohn Co | Enteric-coated pilules |
NL270408A (de) * | 1960-10-20 | |||
NL297088A (de) * | 1961-01-31 | |||
US3139383A (en) * | 1961-06-26 | 1964-06-30 | Norton Co | Encapsulated time release pellets and method for encapsulating the same |
US3185625A (en) * | 1961-11-08 | 1965-05-25 | Brown Ethan Allan | Injectionable substances |
BE636865A (de) * | 1962-08-31 | |||
US3328256A (en) * | 1963-05-27 | 1967-06-27 | William E Gaunt | Spherical beads and their production |
FR7805M (de) * | 1964-04-09 | 1970-05-20 | ||
CH468192A (de) * | 1964-06-19 | 1969-02-15 | Ciba Geigy | Verfahren zur Herstellung von Arzneimitteln in Perlenform |
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
DE2025774A1 (de) * | 1970-05-26 | 1971-12-09 | Siemens Ag | Verfahren zum Herstellen eines Silicium Planartransistors |
US4178361A (en) * | 1973-09-10 | 1979-12-11 | Union Corporation | Sustained release pharmaceutical composition |
US3922379A (en) * | 1973-12-17 | 1975-11-25 | Abbott Lab | Microencapsulation process |
US4044149A (en) * | 1974-05-13 | 1977-08-23 | Eli Lilly And Company | Aluminum salts of substituted phenylalkanoic acids and pharmaceutical suspensions prepared therefrom |
US4140755A (en) * | 1976-02-13 | 1979-02-20 | Hoffmann-La Roche Inc. | Sustained release tablet formulations |
US4167558A (en) * | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
JPS52151717A (en) * | 1976-06-09 | 1977-12-16 | Shionogi & Co Ltd | Sugar coating on solid preparations |
US4221778A (en) * | 1979-01-08 | 1980-09-09 | Pennwalt Corporation | Prolonged release pharmaceutical preparations |
US4321253A (en) * | 1980-08-22 | 1982-03-23 | Beatty Morgan L | Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration |
DE3106449A1 (de) * | 1981-02-20 | 1982-09-09 | Röhm GmbH, 6100 Darmstadt | "in magensaft loesliche oder quellbare ueberzugsmasse und ihre verwendung in einem verfahren zum ueberziehen von arzneiformen" |
US4548598A (en) * | 1981-10-09 | 1985-10-22 | Alza Corporation | Parenteral agent dispensing equipment |
US4764380A (en) * | 1982-03-22 | 1988-08-16 | Alza Corporation | Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills |
US4434153A (en) * | 1982-03-22 | 1984-02-28 | Alza Corporation | Drug delivery system comprising a reservoir containing a plurality of tiny pills |
JPH0768117B2 (ja) * | 1983-05-06 | 1995-07-26 | ベスター・インコーポレイテツド | 薬剤放出調整用小胞製剤 |
AU565487B2 (en) * | 1983-09-16 | 1987-09-17 | Fisons Corporation | Liquid prolonged release pharmaceutical formulations containing ionic constituents |
HU190619B (en) * | 1983-11-11 | 1986-09-29 | Bezzegh,Denes,Hu | Process for producing tablets with controlled dissolution of active ingredients |
FR2556964A1 (fr) * | 1983-12-23 | 1985-06-28 | Ile De France | Nouvelles formes galeniques du sulpiride utilisables par voie orale |
US4818763A (en) * | 1984-01-12 | 1989-04-04 | Volker Rusch | Biologically active substance with hormonal properties, production process thereof and utilization of histones for medical purposes |
NZ210785A (en) * | 1984-01-13 | 1987-11-27 | Battelle Development Corp | Liquid dispersions of layered controlled release dosage forms |
DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
WO1987007833A1 (en) * | 1986-06-20 | 1987-12-30 | Shacknai Jonah | Oral sustained release medicament |
US4656028A (en) * | 1986-06-24 | 1987-04-07 | Norcliff Thayer Inc. | Encapsulated antacid |
-
1987
- 1987-10-26 US US07/112,189 patent/US4853229A/en not_active Expired - Lifetime
-
1988
- 1988-10-11 AU AU23635/88A patent/AU623349B2/en not_active Ceased
- 1988-10-20 DE DE3850340T patent/DE3850340T2/de not_active Expired - Fee Related
- 1988-10-20 AT AT88117503T patent/ATE107501T1/de not_active IP Right Cessation
- 1988-10-20 EP EP88117503A patent/EP0313992B1/de not_active Expired - Lifetime
- 1988-10-20 ES ES88117503T patent/ES2055727T3/es not_active Expired - Lifetime
- 1988-10-21 KR KR1019880013766A patent/KR950013749B1/ko not_active IP Right Cessation
- 1988-10-25 ZA ZA887976A patent/ZA887976B/xx unknown
- 1988-10-25 PT PT88854A patent/PT88854B/pt not_active IP Right Cessation
- 1988-10-25 CA CA000581194A patent/CA1318825C/en not_active Expired - Fee Related
- 1988-10-25 IE IE321088A patent/IE61942B1/en not_active IP Right Cessation
- 1988-10-26 JP JP63270590A patent/JP2840260B2/ja not_active Expired - Lifetime
- 1988-10-26 DK DK595688A patent/DK595688A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE107501T1 (de) | 1994-07-15 |
EP0313992A1 (de) | 1989-05-03 |
KR890006223A (ko) | 1989-06-12 |
JPH01149716A (ja) | 1989-06-12 |
CA1318825C (en) | 1993-06-08 |
EP0313992B1 (de) | 1994-06-22 |
PT88854A (pt) | 1989-07-31 |
KR950013749B1 (ko) | 1995-11-15 |
PT88854B (pt) | 1995-05-31 |
US4853229A (en) | 1989-08-01 |
DK595688A (da) | 1989-04-27 |
DK595688D0 (da) | 1988-10-26 |
AU2363588A (en) | 1989-06-08 |
IE61942B1 (en) | 1994-11-30 |
AU623349B2 (en) | 1992-05-14 |
ZA887976B (en) | 1989-07-26 |
DE3850340T2 (de) | 1994-10-27 |
JP2840260B2 (ja) | 1998-12-24 |
IE883210L (en) | 1989-04-26 |
ES2055727T3 (es) | 1994-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3850340D1 (de) | Zahlreiche kleine Pillen in flüssiger Darreichungsform. | |
DE3586713D1 (de) | Vorrichtung zur kontrollierten abgabe von arzneimittelwirkstoffen. | |
FR2499859B1 (fr) | Dispositif d'administration simultanee d'une substance pharmaceutique et d'un activateur d'absorption percutanee | |
NO176466C (no) | Fremgangsmåte til fremstilling av doseringsenhet for avgivelse av et aktivt middel til et bruksmiljö | |
NO872412L (no) | Fremgangsmaate og anordning til avgivelse av et middel i et biologisk miljoe. | |
EP0257786A3 (en) | Dosage form for delivering acid sensitive beneficial agent | |
DE2964438D1 (en) | Method of making solid medicaments with active agents applied in form of drops | |
DE68926169T2 (de) | Heilmittel enthaltende matrize | |
AT384737B (de) | Vorrichtung zur stroemungskonstanten abgabe fluessiger arzneimittel | |
DE68910159T2 (de) | Dosierform für Verabreichung in der Humanmedizin. | |
ATA88084A (de) | Vorrichtung zur kontrollierten abgabe eines wirkstoffes | |
ATE63813T1 (de) | Pharmazeutische zusammensetzungen von dihydrocodeine/ibuprofen und verfahren. | |
ATE225647T1 (de) | Dosierungsform zur verabreichung von flüssige arzneimittel formulierung | |
ATE63059T1 (de) | Vorrichtung mit zwei schichten zur freisetzung von arzneimitteln. | |
DE69002034D1 (de) | Vorrichtung mit gesteuerter wirkstoffabgabe. | |
ATE76574T1 (de) | Osmotisches system zur verabreichung von verduennten loesungen. | |
BE894597A (fr) | Nouvelles xanthines a activite pharmacologique, leur procede d'obtention, les compositions pharmaceutiques les contenant et leur utilisation en medecine humaine | |
DE3873027D1 (de) | Vorrichtung zur langsamen abgabe eines fluessigen wirkstoffs. | |
DK268889A (da) | Cykliske d-cys6-peptidforbindelser, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse | |
BE841596A (fr) | Dispositif d'emmagasinage et de distribution de medicaments | |
FR2310123A1 (fr) | Dispositif d'emmagasinage et de distribution de medicaments | |
ATE129405T1 (de) | Ionophore enthaltende abgabevorrichtung. | |
FR2578516B1 (fr) | Dispositif de conditionnement et de transfert de produit liquide, applicable notamment en medecine veterinaire | |
SE8701593D0 (sv) | Doseringsanordning for lekemedel och dylikt | |
JPS5340981A (en) | Method of stocking containers for containing medical solution and pallet used for the mthod |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |