DE3783163T2 - Arzneimittelzubereitungen mit verzoegerter freisetzung. - Google Patents

Arzneimittelzubereitungen mit verzoegerter freisetzung.

Info

Publication number
DE3783163T2
DE3783163T2 DE8787108670T DE3783163T DE3783163T2 DE 3783163 T2 DE3783163 T2 DE 3783163T2 DE 8787108670 T DE8787108670 T DE 8787108670T DE 3783163 T DE3783163 T DE 3783163T DE 3783163 T2 DE3783163 T2 DE 3783163T2
Authority
DE
Germany
Prior art keywords
release drug
drug preparations
delivered
delivered release
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787108670T
Other languages
English (en)
Other versions
DE3783163D1 (de
Inventor
Issac Ghebre Sellassie
Nesbitt, Jr
Uma Iyer
Mahdi B Fawzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of DE3783163D1 publication Critical patent/DE3783163D1/de
Application granted granted Critical
Publication of DE3783163T2 publication Critical patent/DE3783163T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • CCHEMISTRY; METALLURGY
    • C30CRYSTAL GROWTH
    • C30BSINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B33/00After-treatment of single crystals or homogeneous polycrystalline material with defined structure
DE8787108670T 1986-06-17 1987-06-16 Arzneimittelzubereitungen mit verzoegerter freisetzung. Expired - Fee Related DE3783163T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/875,146 US4810501A (en) 1986-06-17 1986-06-17 Sustained release pharmaceutical preparations

Publications (2)

Publication Number Publication Date
DE3783163D1 DE3783163D1 (de) 1993-02-04
DE3783163T2 true DE3783163T2 (de) 1993-04-22

Family

ID=25365278

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787108670T Expired - Fee Related DE3783163T2 (de) 1986-06-17 1987-06-16 Arzneimittelzubereitungen mit verzoegerter freisetzung.

Country Status (17)

Country Link
US (1) US4810501A (de)
EP (1) EP0249949B1 (de)
JP (1) JPS63258406A (de)
KR (1) KR950003609B1 (de)
AT (1) ATE83649T1 (de)
AU (1) AU611085B2 (de)
CA (1) CA1297016C (de)
DE (1) DE3783163T2 (de)
DK (1) DK305287A (de)
ES (1) ES2053470T3 (de)
FI (1) FI872652A (de)
GR (1) GR3006981T3 (de)
NO (1) NO872499L (de)
NZ (1) NZ220722A (de)
PH (1) PH24152A (de)
PT (1) PT85105B (de)
ZA (1) ZA873851B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
US4999189A (en) * 1988-11-14 1991-03-12 Schering Corporation Sustained release oral suspensions
US5186930A (en) * 1988-11-14 1993-02-16 Schering Corporation Sustained release oral suspensions
GB9025372D0 (en) * 1990-11-22 1991-01-09 Nat Res Dev Pharmaceutical dosage forms
US5683719A (en) * 1990-11-22 1997-11-04 British Technology Group Limited Controlled release compositions
US5358723A (en) * 1991-11-26 1994-10-25 Warner-Lambert Company Process and composition for the development of controlled release gemfibrozil dosage form
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5681585A (en) 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5348747A (en) * 1992-03-05 1994-09-20 American Home Products Corporation Pharmaceutical coating sugars
US5429822A (en) * 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
KR950703935A (ko) * 1992-11-30 1995-11-17 밋첼 아이, 커시너 맛을 차단하는 약제학적 조성물
US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
FR2723846B1 (fr) * 1994-08-24 1997-06-13 Hi Pharmtech Forme pharmaceutique solide pour l'administration d'une substance active liquide liposoluble
AU5655296A (en) * 1995-05-09 1996-11-29 Colorcon Limited Electrostatic coating
US7008668B2 (en) * 1995-05-09 2006-03-07 Phoqus Pharmaceuticals Limited Powder coating composition for electrostatic coating of pharmaceutical substrates
GB9623634D0 (en) 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
US6479082B1 (en) 1996-12-23 2002-11-12 Wm. Wrigley, Jr. Co. Process of increasing flavor release from chewing gum using hydroxypropyl cellulose and product thereof
DK1009387T3 (da) 1997-07-02 2006-08-14 Euro Celtique Sa Stabiliserede tramadolformuleringer med langvarig frigivelse
EP0943341A1 (de) * 1998-02-18 1999-09-22 Oscar Gold Verfahren zur Herstellung von Erythromycin Macrolide enthaltenden Granulaten und Arzneimitteln
DE60037799D1 (de) 1999-04-01 2008-03-06 Wrigley W M Jun Co Strukturen mit langanhaltender geschmacksabgabe fuer kaugummi
GB0002305D0 (en) * 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
FR2807771A1 (fr) * 2000-04-12 2001-10-19 Atofina Procede de modification hydrophile d'un substrat mettant en jeu un traitement en milieu aqueux par un polymere soluble dans l'eau et thermosensible
EP1429728A1 (de) * 2001-08-29 2004-06-23 SRL Technologies, Inc. Zubereitungen mit verzögerter freisetzung
GB2420298B (en) * 2003-06-18 2006-08-23 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
GB0330171D0 (en) * 2003-12-30 2004-02-04 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
GB0407312D0 (en) * 2004-03-31 2004-05-05 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
AR055346A1 (es) * 2005-06-30 2007-08-22 Sod Conseils Rech Applic Composiciones farmaceuticas de glp -1
US11311490B2 (en) 2005-08-10 2022-04-26 Add Advanced Drug Delivery Technologies Ltd. Oral preparation with controlled release
KR101402592B1 (ko) * 2006-03-06 2014-06-17 에스케이바이오팜 주식회사 피록시캄-무기물 복합체를 포함하는 경피투여 조성물 및이를 이용한 패치시스템
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
KR101816626B1 (ko) * 2014-04-16 2018-01-09 가부시키가이샤 고마쓰 세이사쿠쇼 아이들러, 엔드레스 트랙식 주행 장치 및 마모 플레이트

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2897121A (en) * 1957-06-04 1959-07-28 Upjohn Co Pharmaceutical composition
US3119738A (en) * 1962-04-12 1964-01-28 Wisconsin Alumni Res Found Medication for ruminants
US3594470A (en) * 1968-02-19 1971-07-20 Abbott Lab Chewable tablets including coated particles of pseudoephedrine-weak cation exchange resin
FR2183546B1 (de) * 1972-05-10 1975-06-20 Servier Lab
US4011061A (en) * 1975-03-20 1977-03-08 Minnesota Mining And Manufacturing Company Articles providing sustained release and method of making
US4284444A (en) * 1977-08-01 1981-08-18 Herculite Protective Fabrics Corporation Activated polymer materials and process for making same
DE2908794C2 (de) * 1978-03-09 1984-09-13 Japan Atomic Energy Research Institute, Tokio/Tokyo Verfahren zur Herstellung eines eine physiologisch aktive Substanz enthaltenden Polymerpräparates
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4308251A (en) * 1980-01-11 1981-12-29 Boots Pharmaceuticals, Inc. Controlled release formulations of orally-active medicaments
IT1176853B (it) * 1984-10-02 1987-08-18 Eurand Spa Procedimento per ottenere una formulazione a rilascio controllato di componenti solubili in acqua
US4600645A (en) * 1985-01-31 1986-07-15 Warner-Lambert Company Process for treating dosage forms

Also Published As

Publication number Publication date
DE3783163D1 (de) 1993-02-04
KR880000106A (ko) 1988-03-23
PH24152A (en) 1990-03-22
ES2053470T3 (es) 1994-08-01
GR3006981T3 (de) 1993-06-30
NO872499D0 (no) 1987-06-16
JPS63258406A (ja) 1988-10-25
EP0249949B1 (de) 1992-12-23
DK305287D0 (da) 1987-06-16
EP0249949A2 (de) 1987-12-23
PT85105A (en) 1987-07-01
ATE83649T1 (de) 1993-01-15
NO872499L (no) 1987-12-18
CA1297016C (en) 1992-03-10
FI872652A (fi) 1987-12-18
PT85105B (pt) 1990-03-08
ZA873851B (en) 1987-11-25
NZ220722A (en) 1990-06-26
DK305287A (da) 1987-12-18
EP0249949A3 (en) 1988-03-16
FI872652A0 (fi) 1987-06-15
AU611085B2 (en) 1991-06-06
KR950003609B1 (ko) 1995-04-17
US4810501A (en) 1989-03-07
AU7419687A (en) 1987-12-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee