DE3781946D1 - Therapeutische oder radiodiagnostische substanz. - Google Patents

Therapeutische oder radiodiagnostische substanz.

Info

Publication number
DE3781946D1
DE3781946D1 DE8787304796T DE3781946T DE3781946D1 DE 3781946 D1 DE3781946 D1 DE 3781946D1 DE 8787304796 T DE8787304796 T DE 8787304796T DE 3781946 T DE3781946 T DE 3781946T DE 3781946 D1 DE3781946 D1 DE 3781946D1
Authority
DE
Germany
Prior art keywords
binding protein
compound
administered
target site
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787304796T
Other languages
English (en)
Other versions
DE3781946T2 (de
Inventor
David A Goodwin
Claude Meares
Michael Mccall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Application granted granted Critical
Publication of DE3781946D1 publication Critical patent/DE3781946D1/de
Publication of DE3781946T2 publication Critical patent/DE3781946T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
    • A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
    • A61K47/6898—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies using avidin- or biotin-conjugated antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DE8787304796T 1986-06-23 1987-05-29 Therapeutische oder radiodiagnostische substanz. Expired - Fee Related DE3781946T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/877,327 US4863713A (en) 1986-06-23 1986-06-23 Method and system for administering therapeutic and diagnostic agents

Publications (2)

Publication Number Publication Date
DE3781946D1 true DE3781946D1 (de) 1992-11-05
DE3781946T2 DE3781946T2 (de) 1993-02-18

Family

ID=25369744

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787304796T Expired - Fee Related DE3781946T2 (de) 1986-06-23 1987-05-29 Therapeutische oder radiodiagnostische substanz.

Country Status (5)

Country Link
US (1) US4863713A (de)
EP (1) EP0251494B1 (de)
JP (1) JPH085808B2 (de)
AT (1) ATE81018T1 (de)
DE (1) DE3781946T2 (de)

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Also Published As

Publication number Publication date
EP0251494B1 (de) 1992-09-30
US4863713A (en) 1989-09-05
ATE81018T1 (de) 1992-10-15
JPS635033A (ja) 1988-01-11
EP0251494A3 (en) 1990-01-10
JPH085808B2 (ja) 1996-01-24
DE3781946T2 (de) 1993-02-18
EP0251494A2 (de) 1988-01-07

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