DE3781177D1 - Gemischte phosphorsaeurediester, ihre herstellung und verwendung als entzuendungshemmende mittel. - Google Patents

Gemischte phosphorsaeurediester, ihre herstellung und verwendung als entzuendungshemmende mittel.

Info

Publication number
DE3781177D1
DE3781177D1 DE8787301842T DE3781177T DE3781177D1 DE 3781177 D1 DE3781177 D1 DE 3781177D1 DE 8787301842 T DE8787301842 T DE 8787301842T DE 3781177 T DE3781177 T DE 3781177T DE 3781177 D1 DE3781177 D1 DE 3781177D1
Authority
DE
Germany
Prior art keywords
production
phosphoric acid
inflammatory agent
acid diesters
mixed phosphoric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787301842T
Other languages
English (en)
Other versions
DE3781177T2 (de
Inventor
Itaru Yamamoto
Kazumi Ogata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3781177D1 publication Critical patent/DE3781177D1/de
Publication of DE3781177T2 publication Critical patent/DE3781177T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE8787301842T 1986-03-04 1987-03-03 Gemischte phosphorsaeurediester, ihre herstellung und verwendung als entzuendungshemmende mittel. Expired - Fee Related DE3781177T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61046878A JPS62205091A (ja) 1986-03-04 1986-03-04 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤

Publications (2)

Publication Number Publication Date
DE3781177D1 true DE3781177D1 (de) 1992-09-24
DE3781177T2 DE3781177T2 (de) 1992-12-17

Family

ID=12759612

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787301842T Expired - Fee Related DE3781177T2 (de) 1986-03-04 1987-03-03 Gemischte phosphorsaeurediester, ihre herstellung und verwendung als entzuendungshemmende mittel.

Country Status (6)

Country Link
US (1) US4914197A (de)
EP (1) EP0236120B1 (de)
JP (1) JPS62205091A (de)
CA (1) CA1269669A (de)
DE (1) DE3781177T2 (de)
ES (1) ES2051735T3 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2526059B2 (ja) * 1987-04-28 1996-08-21 千寿製薬株式会社 抗潰瘍剤
PH25859A (en) * 1988-01-11 1991-12-02 Takeda Chemical Industries Ltd Composition for treatment of ischemic disorder
US4939128A (en) * 1988-04-25 1990-07-03 Takeda Chemical Industries, Ltd. Ester of ascorbic acid 2-phosphate and pharmaceutical use
JP2736794B2 (ja) * 1988-12-26 1998-04-02 千寿製薬株式会社 歯垢生成防止剤
US5500444A (en) * 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs
JP2854631B2 (ja) * 1989-11-21 1999-02-03 千寿製薬株式会社 糖尿病合併症および老化によって引き起こされる疾患の予防・治療剤
FR2657526B1 (fr) * 1990-01-31 1994-10-28 Lvmh Rech Utilisation d'un phosphate d'alpha-tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, dermatologiques, ou pharmaceutiques; compositions ainsi obtenues.
WO1992007544A1 (en) * 1990-10-26 1992-05-14 Shiseido Co., Ltd. External preparation for skin
US5643597A (en) * 1991-08-01 1997-07-01 Lvmh Recherche Use of a tocopherol phosphate or one of its derivatives for the preparation of cosmetic or pharmaceutical compositions and compositions so obtained
FR2679904A1 (fr) * 1991-08-01 1993-02-05 Lvmh Rech Utilisation d'un phosphate de tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, ou pharmaceutiques et compositions ainsi obtenues.
US5164375A (en) * 1991-09-27 1992-11-17 Merck & Company, Inc. Antifungal agent
EP0535283A1 (de) * 1991-10-02 1993-04-07 Merrell Dow Pharmaceuticals Inc. Tocopherol Analoge mit kardioprotektiver Wirkung
EP0550292A1 (de) * 1992-01-02 1993-07-07 Merrell Dow Pharmaceuticals Inc. Tocopherol-Analog zum Gewebeschutz
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
JPH05286848A (ja) * 1992-04-10 1993-11-02 Senju Pharmaceut Co Ltd 浴用剤
US5846516A (en) * 1992-06-03 1998-12-08 Alliance Pharmaceutial Corp. Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications
US5350775A (en) * 1992-07-20 1994-09-27 Showa Denko K.K. Benzopyran derivative, method for producing the same and use thereof
CA2115606A1 (en) * 1993-02-22 1994-08-23 Takahiro Matsumoto Intraocular irrigating and enucleated eyeball preservative composition
TW252918B (de) * 1993-03-31 1995-08-01 Senju Pharma Co
CA2133784A1 (en) * 1993-10-22 1995-04-23 Kazumi Ogato Deodorant composition
JPH07196516A (ja) * 1993-12-29 1995-08-01 Senju Pharmaceut Co Ltd 痔疾患治療剤
JPH07215801A (ja) * 1994-01-28 1995-08-15 Senju Pharmaceut Co Ltd 肺保存剤および肺保存方法
JPH07277988A (ja) * 1994-04-05 1995-10-24 Senju Pharmaceut Co Ltd 局所用掻痒除去、治療剤
JP3362501B2 (ja) * 1994-04-28 2003-01-07 千寿製薬株式会社 角膜障害治療剤
JPH07330501A (ja) 1994-06-14 1995-12-19 Senju Pharmaceut Co Ltd 肝保存剤および肝保存方法
CA2152693A1 (en) * 1994-08-05 1996-02-06 Kazumi Ogata Therapeutic composition for pancreatitis
US5795912A (en) * 1995-04-26 1998-08-18 Senju Pharmaceutical, Co., Ltd. Therapeutic composition for corneal impairment
CA2244535A1 (en) * 1995-05-15 2000-01-30 Avon Products, Inc. Novel uses for ascorbyl-phosphoryl-cholesterol in topical compositions
US6162450A (en) * 1995-05-15 2000-12-19 Avon Products, Inc. Uses of ascorbyl-phosphoryl-cholesterol and compositions for practicing same
CA2179940A1 (en) * 1995-07-18 1997-01-19 Kazumi Ogata Antiallergic composition comprising a phosphoric diester compound
JP4115524B2 (ja) * 1995-10-17 2008-07-09 昭和電工株式会社 高純度トコフェロールリン酸エステル類、その製造方法、その分析方法並びに化粧料
JPH09194375A (ja) * 1996-01-17 1997-07-29 Senju Pharmaceut Co Ltd 免疫抑制作用増強剤
JP4346239B2 (ja) 1997-12-24 2009-10-21 千寿製薬株式会社 ビタミンｅ誘導体
WO1999065498A1 (fr) * 1998-06-19 1999-12-23 Senju Pharmaceutical Co., Ltd. Agents pour remedier aux effets secondaires de l'hormone corticosurrenale
US6048891A (en) * 1998-12-17 2000-04-11 Loma Linda University Medical Center Use of γ-tocopherol and its oxidative metabolite LLU-α in the treatment of natriuretic disease
KR20020025181A (ko) * 1999-07-08 2002-04-03 요시다 쇼지 말레산(또는 푸마르산) 디에스테르 화합물
ES2281518T3 (es) * 2001-06-06 2007-10-01 Senju Pharmaceutical Co., Ltd. Aducto de diester del acido l-ascorbico-acido 2-o-maleico y alfa-tocoferol 1-propanol y procedimiento para producirlo.
US6645514B1 (en) 2002-12-19 2003-11-11 Access Business Group International, Llc Increasing skin cell renewal with water-soluble Vitamin E
AT500404A1 (de) * 2003-07-17 2005-12-15 Jsw Res Forschungslabor Gmbh Chemische verbindungen enthaltend tocopherol sowie zumindest einen weiteren pharmazeutischen wirkstoff
US8865228B2 (en) 2006-02-21 2014-10-21 Mary Kay Inc. Stable vitamin C compositions
CA2733253C (en) * 2008-08-26 2016-12-13 Gasfrac Energy Services Inc. Volatile-phosphorus free gelling agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5944375A (ja) * 1982-09-06 1984-03-12 Senjiyu Seiyaku Kk α−トコフエロ−ルリン酸エステルの安定な水溶液
JPS59219295A (ja) * 1983-05-30 1984-12-10 Senjiyu Seiyaku Kk リン酸ジエステルまたはその塩およびそれらの製造法

Also Published As

Publication number Publication date
JPS62205091A (ja) 1987-09-09
ES2051735T3 (es) 1994-07-01
EP0236120A3 (en) 1989-10-11
EP0236120B1 (de) 1992-08-19
CA1269669A (en) 1990-05-29
EP0236120A2 (de) 1987-09-09
DE3781177T2 (de) 1992-12-17
JPH0523274B2 (de) 1993-04-02
US4914197A (en) 1990-04-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee