DE3778281D1 - Immunreagenzien mit erhoehter affinitaet zum nachweis und zur zerstoerung von spezifischen targetzellen. - Google Patents

Immunreagenzien mit erhoehter affinitaet zum nachweis und zur zerstoerung von spezifischen targetzellen.

Info

Publication number
DE3778281D1
DE3778281D1 DE8787430031T DE3778281T DE3778281D1 DE 3778281 D1 DE3778281 D1 DE 3778281D1 DE 8787430031 T DE8787430031 T DE 8787430031T DE 3778281 T DE3778281 T DE 3778281T DE 3778281 D1 DE3778281 D1 DE 3778281D1
Authority
DE
Germany
Prior art keywords
target cells
reagents
synthetic
detecting
specific target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787430031T
Other languages
English (en)
Inventor
Jacques Barbet
Michel Delaage
Doussal Jean-Marc Le
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunotech SAS
Original Assignee
Immunotech Partners SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunotech Partners SA filed Critical Immunotech Partners SA
Application granted granted Critical
Publication of DE3778281D1 publication Critical patent/DE3778281D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Optics & Photonics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8787430031T 1986-09-19 1987-09-16 Immunreagenzien mit erhoehter affinitaet zum nachweis und zur zerstoerung von spezifischen targetzellen. Expired - Lifetime DE3778281D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8613146A FR2604092B1 (fr) 1986-09-19 1986-09-19 Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo

Publications (1)

Publication Number Publication Date
DE3778281D1 true DE3778281D1 (de) 1992-05-21

Family

ID=9339117

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787430031T Expired - Lifetime DE3778281D1 (de) 1986-09-19 1987-09-16 Immunreagenzien mit erhoehter affinitaet zum nachweis und zur zerstoerung von spezifischen targetzellen.

Country Status (11)

Country Link
US (1) US5256395A (de)
EP (1) EP0263046B1 (de)
JP (1) JP2612454B2 (de)
KR (1) KR900005622B1 (de)
AT (1) ATE74769T1 (de)
AU (1) AU613318B2 (de)
CA (1) CA1306414C (de)
DE (1) DE3778281D1 (de)
ES (1) ES2032468T3 (de)
FR (1) FR2604092B1 (de)
GR (1) GR3004914T3 (de)

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Also Published As

Publication number Publication date
JPS63159327A (ja) 1988-07-02
AU613318B2 (en) 1991-08-01
GR3004914T3 (de) 1993-04-28
CA1306414C (en) 1992-08-18
JP2612454B2 (ja) 1997-05-21
FR2604092B1 (fr) 1990-04-13
ATE74769T1 (de) 1992-05-15
US5256395A (en) 1993-10-26
FR2604092A1 (fr) 1988-03-25
KR880004312A (ko) 1988-06-07
ES2032468T3 (es) 1993-02-16
EP0263046B1 (de) 1992-04-15
AU7865687A (en) 1988-04-21
KR900005622B1 (ko) 1990-07-31
EP0263046A1 (de) 1988-04-06

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