DE3713846A1 - Device for suction diagnostics or sucking injection - Google Patents

Abstract

A device for the automatic measurement of metabolic states remote from the tip of a puncturing means with the aid of a suction cup with or without injection of liquids under the skin of a human being or an animal, in which the axis of the suction cup is arranged transversely to the longest dimension of the housing, and the puncturing styles are moved, for diagnostic purposes only, laterally past the suction cup opening even without a sleeve for the purpose of exchanging it, and their shaft is preferably completely retracted in a style bore before use. At least the force of the manual lifting of the suction cup is utilized via spring tension in order to perform automatic functions, and the lifting can be also utilized, under the action of a pin on a zigzag profile on the outside of a wheel, for controlling the functioning, for example for transporting the puncturing means to the side. Further special features of the mechanical system as are obtained by reducing the height above the suction cup relate to innovations such as a plate at the end of the shaft of the puncturing means, the cap engaging over it or the vertical displacement of the latter via a Bowden cable. Where special force is required (as could be avoided on opening a gas pressure valve by lifting the valve seat inside the gas pressure chamber, with electrical heating of a bimetallic bridge), for example for a sucking injector of corresponding design, ... Original abstract incomplete.

Description

The invention relates to the field of medicine technology, more specifically in the fields of medical Diagnostics and injection therapy, in the individual The area is also called a magnetic switchgear electrical switching technology addressed.

The invention is an additional application to P 37 08 031.8 with the title "Measuring device or injection device device with measuring device or device for material acquisition for a measuring device for metabolism blood levels by puncture using Vacuum inside a suction cup when relocated the measuring zone outside the peak area of the punk tion device "; the main application is again a direct specification of both PCT WO 86/01 728 "In ejection device with sensor "as well as from Euro-Pa tent registration 8 59 04 438.1 (simultaneously with the former) "Device for automatic metabolic control". The last two filings were made in several countries unites in one application, which by ge common task seemed justified: Especially with the Treatment of diabetes insulin injection to improve therapy by immediately before the injection the blood sugar level is determined and the measured values obtained for dose correction at the closing insulin injection should be done. Yourself the proposed facilities were understandable usable for purely diagnostic use. Exclusion For this reason, diagnostic devices appear to be useful moderate because the vast majority of diabetic patients get by with diet or tablet treatment; Furthermore exists in pharmacies, medical practices and clinics diagnostic needs. With regard to the suction application  The invention is based primarily on the continuous further development since registration P 25 51 991, 25 51 992 and 25 51 993 in 1975 (with Priori from registrations in England).

The task remained the same: Above all for diabetic patients to enable pain-free diagnosis and pain-free injection therapy by means of a handy, if possible pocket-sized device that requires little maintenance and is easy to use with a high level of functional reliability, i.e. automation of the functional sequence and thereby as possible low manufacturing costs and economic efficiency at all. As part of the task, the remedies against premature lifting of the suction cup by lever action of the device handle part seemed to be incomplete so far. The solution presented here avoids such an elongated handle part in that the necessary device components are largely arranged next to the suction cup, which leads to an even greater widening of the skin overlay (see point 15 in Fig. 71 WO 86/01 728). The possibility of subdivision of the device in parallel arranged elastic and somewhat flexible interconnected in the transverse direction mostly rigid parts (such as the compressed gas cartridge) also allows a close contact with curved parts of the body, such as limbs. The flat design of the housing allows it to be used unobtrusively on very different parts of the body (which reduces fat tissue and prevents skin irritation), for example under clothing due to the presence of strangers or in the event of air pollution. If the generation of negative pressure by means of a compressed gas cartridge in connection with a gas jet pump was used, this solution offered the additional advantage of controlling the gas outlet valve with a light beam in the area of the raised skin, despite the absolutely limited suction in individual cases (e.g. thicker body hair) to be able to use a longer suction effect. The "lock valve" for a low-emission gas outlet (cf. top left Fig. 19 WO 86/01 728) was simplified in that a stretch-like milling of the pin moving the large seat valve replaced the slide valve. The opening of the smaller Sitzventi les (which is then conveniently arranged next to the large one) is particularly energy-saving when it is opened from within the pressure chamber by the influence of electrical heating of a bi metal bridge. Particularly for the simpler solution of a purely diagnostic device (if there is no longer an indefinite number of dosing pump cycles), the necessary mechanical switching processes can be accomplished by an electric motor, the plungers for tapping the switching plungers depending on the necessary lifting height in the zero position of a wedge bevel, which on circulated on a wheel, are approached to different degrees. The power transmission for lowering and lifting the injection mandrel or the cannula shaft takes place in the example described in more detail via the mediation of two telescopic pipe sockets and a Bowden cable which (to save height) moves the pin out of the cannulas and into their sleeves (item 24 Fig. 7 P 37 08 031.8) replaced. The sleeve itself is omitted in that the puncture mandrel or cannula shaft is completely retracted into the pin of the "cannula" body before use. The sterility of the cannula tip is ensured by a thin membrane in front of it, while the outlet of the shaft exiting at the other end of the body is sealed against the outside air. The "upper" shaft end ver widens like a plate and is covered by a cap at the end of that Bowden cable. Behind the bevel of the tip of the puncture device there is in the example of this "optical sensor device" a "wiping zone", for example of textile properties, which is followed by the "acceptor zone" for the binding of blood or blood components (such as blood plasma); In the starting position before use, the "measuring zone" with the optical indicator spot or stripe must be higher than the acceptor zone, since the optical indicator substances are highly toxic and must not be dragged into the skin. Before the measurement, the aspirated skin tip is first examined optically for changes in pigment and density in order to avoid piercing diseased skin areas. (Where this skin check is not provided, the level of the skin tip will be checked more easily by means of electrical contact). The tip of the puncture device is now pressed through the skin by means of that Bowden cable during the second of its bloodlessness under suction. The lowering of the shaft takes place so far that the acceptor zone lies within the ring of injury to the skin and is loaded with blood in its hyperemic phase (the stage of blood filling). Now the shaft is withdrawn until the acceptor zone with its blood comes to lie over the measuring zone, the suction bell can be ventilated again and the device can be removed from the skin. After a specified blood contact time, the shaft is pulled further upward, so that the wiping zone cleans the measuring zone of blood (if this is necessary at all, ie if blood cells are carried over which complicate the optical reflex measurement). Also the bevel zone must have passed the measuring zone in order to release the optical path from the optical fiber to the light measuring cell (detector) - with transpa rens of the "cannula" body, as is understood. The blood glucose can now be read from the display by signaling. Of course, all measured values can also be printed out on a registration tape, for example when electrical charging, if necessary, a run check. The suction bell operates by the action between the guide pin and the zigzag groove backdrop on the initial section of its raising when the skin is pressed against the "cannulas" in order to then be sealed airtight centrally from the lower end of the "cannulas" leaning against a lever. Since the cannula magazine is fixed in height in the example just described and the suction bell remains "retracted" after use, a re-venting valve is required, for example a seat valve, which is actuated against spring pressure after the shaft has been withdrawn from the skin via the electrical switching mechanism. The design can - what is desirable - be made even lower if the individual shaft zones, such as wiping, acceptor and measuring zone are made even smaller, which does not pose any difficulties with the good possibility of light focusing. The plate-like widening of the upper shaft end instead of an extension piece with a central hole for the push pin serves to shorten this, but also to simplify production. Characterized in that the diameter of this plate surpasses that of the body of the puncture device, the cap can also move closer to the end of the push pin or Bowden cable. The cap can also directly surround the "cannula" body (which is then expediently circular in the upper part), where no shaft movement is provided. For example, a variation is given in which a capillary for taking blood is cast rigidly into the body parallel to a ventilation hole and both cavities are sealed at the top by a cap. The bodies have holes which are traversed by the holding threads which hold the bodies in series. The thread elasticity can thus be used for stretching over a longer distance, in particular if the cannula for positioning above the suction cup opening is pressed below the level of the other bodies via a rail guide. When using reaction capillaries for UV light determination, a suitable light source can be used from the outside via optical fibers or directly. Determinations other than glucose can also be carried out, for example a blood alcohol analysis, in which the extent of bodily harm can certainly also play a role in terms of reasonableness. When designing an injector, the problem of a higher effort also arises with the need for additional functions (if only because of the device against liquid pressure in the cannula area). The considerable muscle strength of the hand, which is always present, often appears to be superior to electric drives. It is quite reasonable for the patient to pull a strap out of the device instead of releasing the suction cup lock by pushing a button (in the solution of FIGS. 1-3 and 5) if the spring winding that takes place is staggered one after the other. This is done in an example by means of a wire bracket, which one after the other horizontally arranged (the vertical staggering is of course also possible) takes along slider under tension one spring (compression or tension spring, depending on the expediency and over each expedient single route). The wire bracket is guided through a lateral (double-sided) link guide after the respective spring has been determined by a raster over the stop edge on the slide and comes in front of the stop edge of the follow-up slide, etc. Finally, the suction bell is lifted against its return springs into the housing and there using a wedge fixed. The drawstring itself is expediently placed around the housing and fastened in a taut state by means of an angular clamp (correspondingly when binding together in the ski). The functional state of the device can be easily recognized from the position of the strap, and the clip (with the corresponding auxiliary bar) can be stripped from the housing even under the clothing. By means of a soft tension spring (like that of a tape measure), the spring clip is then returned to its initial position while shortening the tension. The edge of the suction bell comes out of the housing level and can now be pressed against the skin. Here, too, springs can be tensioned to perform the necessary functions (so to speak without additional requirements for the user). In the example shown - a total device conception of an injector was not presented here - three springs are tensioned in addition to the return spring for the suction bell (in double), which serve to approach and remove the cannula body and the puncture agent. It is understood that the suction is triggered at the moment when the suction bell is fully raised. The triggering can be mediated mechanically or via a light barrier by offering this a special reflex point. The light barrier or light "barriers" also serve to inquire about the health of the skin at the point of the puncture which is then triggered and to monitor the height of the skin at the top during the necessary puncture or injection duration. The monitoring function can also be done via an electrical touch switch or in previously published versions. With the injector - even when using some mechanical switches - there is a need for many electrical switching operations. Due to the high weight and space requirement, the use of several individual magnets is prohibited. The use of two magnets: one for the print function, the other for the function selection, can be avoided. According to the invention the object is achieved in that an electric motor has a disk with a ratchet ring in each of the opposing teeth and on pawls drives a wheel with a wedge oblique, the latter pushes a working lever forward. In the opposite direction of rotation, another disc is driven with wedge bevels, and the tappet movement caused by a linkage on a zigzag profile on the outside of the switching disc is transmitted and rotated in stages, so that the tappet always over the next hole of the connecting drum for shift linkage or Bowden cables and triggers the respective function when lowering. The advantage of the magnetic switching devices is generally that the repetition of the individual working strokes on any function is arbitrary, which is of crucial importance for an alternating metering by means of pulse pumps. The advantage of the type with motor drive in the sense of a rotor lies in the better use of power (i.e. a weight saving), since the work phase can be spread over a longer period of time, especially where rapid function is not important. The motor can be stopped during the single metering pump stroke, so that no energy loss occurs due to the magnetic function during the liquid movement. In this way, larger strokes can be achieved with justifiable dimensioning of the drive units without additional leverage. Yes, the lifting height of the individual work stages can even be changed if required. This is done in that at the beginning of the reversal of the rotor movement before the action of the wedge bevels on the disc rotation, an adjusting wheel is brought into such a position that it rotates with the rotor axis. About ratchet gear and pawl it communicates its movement when switching back to the work cycle (even before executing one) of an adjusting disc via a screw link, so that the connecting drum and switching disc are approximated to the wedge bevel of the disc and are then suddenly removed again. If the rotor only runs in the changeover direction (i.e. against the work cycle), the frictional connection of the rotor axis with the adjusting wheel is canceled again: a stroke adjustment does not occur. The feed of the working lever can be accelerated in that the wheel with the wedge bevels for the work lever is freely rotatable about the axis and is driven by an adjacent wheel which acts with a knob on a pin of the wheel with wedge bevels. This, however, only after the associated wheel has been rotated back one revolution by means of a rotary spring. In this way, the knob hits the pin of the wheel at a certain speed, which immediately gains momentum. Another way of avoiding the slow lever jacking, as it is annoying for the preferred metering pumps, is the one in which a disc with compression spring to the wheel with wedge oblique towards the effect of a pin on the wedge oblique on the vertical movement by the Profilge the axle or a cross pin in the axle is prevented. This accumulates pressure in a Fe, which becomes jerky when an axially close slot ben passage of the cross pin the disk movement and thus allows the work cycle. The mechanism can also be used for the backward movement of a working lever, or for both directions.

When using solenoids as drive means the rotation of the switching disc can be varied che power supply to the solenoid can be effected. Here can have different lifting heights (e.g. through premature re-excitation of the solenoid), but also higher anchor speed or changed impulse distance (as a mixed form of the first mentioned methods) to be used. In a solution using There is a distance difference for working strokes premature coil excitation via a switch. The unused residual stroke is relatively small, as a result that the force for sector movement of the switching disc in a torsion spring stored over that in a pro filführung caused rotation of a pendulum sleeve, the Reverse movement by ratchet gear and pawl but is prevented from moving  Switch disc always runs ahead. The latter is through two plungers, one of which acts on a Bowden cable, prevented from rotating until these pins left their holes in the drum what can be decided at a very short distance. As an example of a magnetic switching device with difference in anchor speed one specified where the anchor movement in the manner of a hand drill or or music spinning top a kind of flywheel is set in motion, de ren locking pin the downward movement of a perforated disc prevents under pressure spring action. Got the Flywheel due to higher anchor speed higher torque, the locking pin gets into that the slot of the perforated disc, which step deeper can and while using the zigzag profile of the switching disc rotates the same. The described Magnetic switching devices can not only in the Medical technology, also in other diagnostic and therapeutic devices - so with the limb prosthesis tik - but as a means of electrical switching technology nik be used wherever weight and Space must be saved, as with the missiles technology, in model aircraft etc. When using a Instead of adjusting the lifting height of the motor Working lever or in addition to such analogue type also connected to a rotary drive will. The metering pump according to FIG. 78 also WO 86/01 728 and similarly FIG. 7 of the Euro application manure 8 67 30 058.4 was improved in that as Valve body a ball in the place of the spindle occurs which is easier to produce and most importantly to be installed in the hose.

In anticipation of the description of FIG. 4, attention is drawn to the need for suction sealing of the shaft at the top. It can take place inside or on the body through the seal ( 153 ), but also through a stretchable membrane welded to the shaft or a bellows. The suction cup can be re-vented by lifting this seal when the shaft is raised extremely. A bellows in particular can still be used to generate air movement in the shaft channel.

Embodiments

FIG. 1 shows a cross section close to the lid ( A - B in FIG. 2) of the preferred example of a device for suction diagnosis in natural size. The housing box ( 23 ) is divided into three rigid subspaces , which can be slightly bent against each other with appropriate elasticity of the housing base and cover along the (dash-dotted) folding lines a - b and c - d parallel to their longitudinal axis. The housing cover ( 24 ) is turned up around its hinges ( 25 ). In the upper part of the room, the compressed gas bottle ( 26 ) can be seen, which has expanded through the swelling plate ( 27 ) from agar-agar, which expands under the influence of added water and has pressed the opening pin ( 28 ) through the soft iron plate of the compressed gas bottle. The escaped compressed gas, carbonic acid, is located in the gas storage space ( 29 ) and the small seat valve ( 30 ) attached to the bimetal bracket ( 31 ) seals the small channel backflow chamber ( 32 ) from the inside. The large seat valve ( 33 ) is moved by advancing the ground plunger ( 34 ), which cher from the wedge slopes ( 36 ) of the slide ( 37 ), so that the trough ( 35 ) of the plunger the gas outlet to the gas outlet channel ( 38th ) to the gas jet pump ( 39 ) releases (locked here represents Darge). The suction cup rim ( 40 ) against which the three return springs ( 41 ) lean is shown in dashed lines in the middle. From the edge of the suction cup, the guide pin ( 42 ) extends into the zigzag profile of the backdrop of the cannula transport wheel ( 44 ). The "cannula" body conveyor belt is moved by this and is moved in front of the hexagonal drive wheel ( 46 ) with the position-stabilizing plate spring ( 47 ) in front of the light source with detector ( 48 ) in order to be returned in a circle via the left-hand transport wheel. The "cannulas" body, here actually carrier of a bristle or a thorn with subsequent "textile" zone and / or wire or plastic thread, are connected to one another by means of strands, which through holes ( 49 , Fig. 4) of the Kör are passed through ( 49 , Fig. 4). The magnetic switching device consists of an electric motor ( 51 ) and five telescopic tube segment sliders, which are operated one after the other by the wedge bevel of the switching knob ( 53 ) on the switching shaft. From the Bowden trains to the function switches only the one to the slide ( 37 ) for the gas valve opening to the gas jet pump is shown. The battery ( 54 ) for the power supply is to the left of the room for the electronic control, which - like the wiring - was not shown.

Fig. 2 shows a longitudinal section through the Vorrich device according to Fig. 1 (in the section line C - D there) as the. The upper end of the "shaft" of the cannula or the puncture stylus has a plate ( 50 ) as a broadening. The cap ( 55 ) for receiving the same is pulled up by means of the Bowden cable ( 56 ), the bending and continuation of which lies within an inclined cover bulge when terminated with four reins at two opposite ends of the telescopic tube segment connecting piece ( FIG. 3) Which, on the other hand, are connected to the four assigned telescopic tube segment slides ( 52 , FIG. 1), via which they are in the cover bulge ( 57 ). The Gasaus outlet opening ( 58 ) for the gas jet pump ( 39 , Fig. 1) is close to the edge of the lid bulge, so that it can not be closed by the operating hand who can. It is shown how by the guide rail ( 59 ) extending from the cover of the middle puncture pen, which lies above the funnel ( 60 ) of the suction bell, is below the level of the other handles. The latter are fixed on the transport web ( 61 ) and are connected to one another by the holding threads ( 62 ). The right transport wheel ( 63 ) for the puncture pen has on the outside a zigzag profile, which upon engagement of the rotationally secured up and down moving guide pin ( 42 ) from the suction cup at every stroke of the same, ie in its Initial phase until contact of the lower end of the pen with the funnel ( 60 ) of the suction bell, a sector rotation of the transport drum ( 44 ) and thus the replacement of a used pen for an unused one at the low point of the guide rail ( 59 ). In the suction cup area, the junction ( 64 ) of the suction hose from the gas jet pump can also be seen, as well as the hole for the introduction of the optical fibers ( 65 ), which, however, can be thought of as rotated by approximately 45 degrees.

Fig. 3 shows an enlargement of 2: 1 in detail the longitudinal section through a telescopic tube with the sliding sleeve ( 67 ) displaceable in the holding bush ( 66 ), in which in turn the rod ( 68 ) slides. The latter is on the tab ( 69 ) in rigid connection with the telescopic tube slide ( 52 ) for the downward movement of the Bowden cable ( 56 ). The neighboring telescopic tube slide in turn ensured a rightward shift of the sliding sleeve ( 67 ) via the rigid tab connection shown in dashed lines. A tab connection is indicated on the left-hand side by dashed lines, which causes a shift of the telescopic tube slide ei ne left shift of the rod. The tab connection to the left side of the sliding sleeve for the left shift is omitted. The evasive movement of the telescopic tube slider takes place under the influence of the switching knob ( 53 ). The holding bush ( 66 ) is mounted on the axis ( 70 ) for the switch cam drive. Figs. 4 shows at a scale of 2: 1 is a longitudinal section through a puncture stylus with plate (50), shaft (71) with Anschliffzone (a), Abwischzone (b) and acceptor zone (c) and the measuring zone (73) within the stylus bore and the notch ( 72 ) for the guide rail ( 59 , Fig. 1).

Fig. 5 describes in cross section a bolt ( 74 , also in Fig. 1), which is gela on a support rail and by the compression spring ( 76 ) after passage of a cross pin on the suction cup ( 40 ) through a gap ( 77 ) Covered wedge slope prevents the suction bell from returning down under the influence of the return springs ( 41 , Fig. 1). The latching movement of the bolt causes a power interruption at the Schaltkon clock ( 78 ), which transmits the signal to the electronic control unit for opening the compressed gas valve. With manual actuation of the push button ( 80 ) in the housing wall, the bolt is moved against the compression spring by means of a Bowden cable and the gap ( 77 ) allows the cross pin to pass downwards, so that the suction bell lowers under the effect of the return springs.

Fig. 6 describes a puncture pen with a recessed capillary ( 81 ) projecting below ( 81 ), ventilation hole ( 82 ) and at the head end a gap between the capillary and ventilation hole sealingly bridging cover cap ( 82 ) and the cap pe ( 55 ) for conveying the puncture pen. As can be seen on a cross section below, the puncture stylus was given an oval cross section with two bores ( 49 ) for the holding threads, while the top cap was circular. The illustration in longitudinal section in the magnification 1: 2 also includes a suction cup ( 40 ) with funnel ( 60 ) for receiving the puncture stylus and a bowl ( 83 ) with a central opening for the skin passage, which is held by the permanent magnet ring ( 84 ). After the rolling movement that comes to rest under suction from the junction ( 64 ) of the suction hose within the central opening of the shell, this central skin area is lifted into the capillary by lifting the skin with the skin, which can pierce the skin vertically . Cut injuries caused by the capillary when the suction bell is pulled sideways are not to be feared due to the high flexibility of the capillary. This flexibility also requires the exact vertical direction of the puncture. The soft compression spring ( 85 ) brings the cap back into contact with the permanent magnet ring ( 84 ), provided that this is not caused by gravity.

Fig. 7 shows a schematic longitudinal section through a suction cup and the arrangement of Druckfe dern and their blocking grid ( a , b , c , d , e ) with the suction cup connected to the transport web ( 61 ) including trans port drums ( 63 ). The sensor cannula ( 86 ) or the puncture pen is held by the central pin ( 87 ), which is surrounded by the pipe sleeve ( 91 ). The latter carries the compression springs ( 89 ) on three support plates ( 88 ) distributed around it on the circumference (see cross section shown on the right). The spacer pin ( 90 ) from the cover holds the locking grid ( a ). The locking grid ( b , c ) for the other compression spring end are connected to a spacer pin on the trans port web ( 61 ). At the upper end of the Rohrman cuff ( 91 ) lie on three cross arms ( 92 ) each have a compression spring ( 93 ) from below, the lower end of which rests on the transport web ( 61 ). The upper locking grid ( d ) for these springs and the lower locking grid ( e ) are located on the longer retaining web ( 94 ) from the cover (whereby the cover here did not include the housing cover ( 24 ), but a separate cover plate ( 95 ) The two return springs ( 41 ) for the suction bell are only shown in the cross-section on the right When the suction bell is lifted by pressing the skin, the upper ends of the compression spring ( 93 , 89 ) are held by the locking grids ( d , a ), the compression springs are tensioned If the locking grid ( b ) is released - for example by a Bowden cable movement from a magnetic switching device - the cannula lowers to the locking position ( c ), after triggering ( c ) the cannula lowers completely. Now the locking block ( a ) is unblocked In order not to hinder the upward movement of the cannula, which occurs after the locking block ( d ) has been released, after unblocking ( e ) the suction cup is lowered under the influence of its be iden return springs ( 41 , see cross section on the right). Pushing in the wedge lever ( 96 ) from the right finally leads to the suction bell being raised again.

Fig. 8 is a perspective side view of two slide of a spring tensioning device again, which allows the tensioning of springs by means of the movement of a single wire hanger in left arrow direction. The wire bracket lies on the front of the slide ( 37 , for example Fig. 1), the left shifting shortens the compression spring ( 98 ), which is the locking slide ( 99 ) downstream. The toggle ( 100 ) on the slide abuts the locking bracket ( 101 ) and turns it to the left, the second leg of which is supported against the cross plate of the slide - after re-erection by the tension spring ( 102 ) - that the slide toggle under the influence of the compression spring cannot return to the right. The wire bracket is lifted via a swing in the slot guide of the rear side wall (the front one was not drawn) and thus lifted off the front edge of the slide; he then comes to the front edge of the second slide and can take it to the left. This time, the tension spring ( 104 ) is tensioned until the toggle is fixed on the grid ( 105 , symbolically). Such spring tensioning processes can be continued along the entire length of the housing. Thanks to a uniform spring action (similar to a tape measure), the wire bracket is returned to the right after the tensioning process. If the locking slide ( 99 ) is raised, the slide ( 37 ) moves in the direction of the locking plate ( 105 ) and releases the locking of a movement of the pin ( 106 ) which is sprung from top to bottom by the cross pin not holding in the enlarged bore of the locking plate finds more. During a small "push" beyond the distance necessary for triggering, the slot ( 107 ) comes under the second leg of the locking bracket ( 101 ), the thrust force still stored in the compression spring ( 98 ) being that of the tension spring ( 102 ) exceeds, so that the toggle ( 100 ) can overtake the locking angle and the slide returns to the right into the starting position.

If the details of FIGS. 7 and 8 already serve mainly to implement a measuring suction injector within a flat housing, this applies even more to the examples of an electrical magnetic switching device, as are described in FIGS. 9 to 14.

Fig. 9 is a longitudinal section of a Magnetschaltvorrich device again using the electric motor ( 108 ), which achieves a slower rotation of the drive shaft ( 110 ) via the gear ( 109 ). The latter drives the drive wheel ( 111 ) with ratchets on both sides, which, in cooperation with ratchet teeth on the adjacent disks, permit their entrainment only in the opposite direction of movement. For example, the upper disc with the wedge knob ( 112 ) is only carried when it is turned to the left (see the profile on the right), whereby the cross pin ( 113 ) is lifted on the downward-shifting control rod ( 114 ) and thus also the cross pin ( 115 ) , wel cher in the side zigzag profile of the auxiliary wheel ( 116 ) which drives the switching disc ( 11 ) via a toothing. After each individual stroke of the shift rod, due to the sector movement of the shift disc, the tappet ( 14 ) emanating from it comes to lie within the fixed drum ( 12 ) via the respective next bore with a Bowden cable ( 13 ). The reversal of the motor rotation in the direction of rotation to the right, however, results in the entrainment of the lower disk with the wedge knob ( 117 ), which, by advancing the working plunger ( 118 ), causes a lowering of the switching sleeve ( 11 ) and thus also a lowering of the plunger ( 14 ) which pushes the Bowden cable down and is lifted back to the starting position by its springback. Switching or work cycles can now be freely selected depending on the polarity of the motor.

FIG. 10 shows in longitudinal section an addition to the device according to FIG. 9 for the purpose of a jerky design of the working stroke. Although the disk with the wedge knob ( 117 ) is only slowly advanced by the working plunger ( 118 ) in this case when the working shaft ( 110 ) rotates, the drive movement is absorbed by lowering the disk against the compression spring ( 119 ) while the disc ( 120 ) is rotated along the push rod ( 121 ), but cannot sink as long as it can by resting on the cross pin ( 122 ). But as soon as - as shown - a slot in the disc ( 120 ) comes to rest over the cross pin, the latter can suddenly step deeper under the action of the compression spring ( 119 ) and passes its lowering movement on the sleeve ( 124 ) to the functional customer. FIG. 11 shows a device in longitudinal section as in FIG. 10, but both clock movements have been designed in a jerky manner and are equipped with the same (spring) force. This time, the disc ( 120 ) is shown standing above the transverse pin ( 122 ), but at this moment it is stepped through the slot ( 123 ) under the action of the tensioned spring ( 119 ). In the meantime, the lower wedge knob will also tension the lower spring and the disc ( 120 ) will return abruptly upwards. Approaching the iron rod or the plates ( 124 , 125 ) alternately to the permanent magnet ( 16 ) leads to a position stabilization in the end positions (if the spring tension is released).

Fig. 12 shows in longitudinal section a further design of the device according to Fig. 9. As in the two previous figures, the engine and the manual transmission have been omitted. It is about adapting the height of the working strokes in the individual switching positions to changing needs. Via the drive shaft ( 110 ), the rotation is transmitted to the axle tube ( 126 ) by means of the gearwheel via the gearwheel ( 127 ) and communicated to the drive wheel ( 111 ). In the manner already shown in FIG. 9, the rotations to the right are translated into stroke movements of the Bowden cable via the wedge knob ( 117 ). The switching disc ( 11 ) is also rotated in a known manner via the shift linkage ( 114 ) (here, however, without the intermediary of an intermediate wheel). However, the wedge knob ( 112 ) additionally lifts the lever ( 128 ), which is secured against rotation in the rail ( 129 ), and thus the pinion ( 130 ) with internal teeth into a tooth engagement on the drive shaft. But only the counter movement (i.e. to the right in the original working stroke direction) is communicated via the ratchet and pawl of the disk ( 131 ), whose rotation via the bracket ( 134 ), the central shaft and the bracket ( 135 ) onto the adjusting wheel ( 132 ) is transmitted with the groove rising and falling on the outer edge. The fixed hook ( 133 ) in the worm groove brings about the approach and removal of the drum and switching disc to the wedge knob ( 117 ), this distance determining the working stroke height of the plunger ( 14 ). Reversing the motor movement to the left or continuing to turn without reversing the movement switches the pinion ( 130 ) off from the motor rotation. FIG. 13 shows a 2: 1 scale in longitudinal section of an inventive solution with route differentiation; ie the distinction between the working cycle of the magnet and the switching cycle is made via different lifting heights of the magnet. Below is a cross section at the level of section line A - B , on the left-hand side a roll-up in the window area of the pendulum sleeve (above) and the switching sleeve actuated by it (below).

The electromagnet ( 1 ) with its armature plunger ( 2 ) is above the pendulum sleeve ( 3 ), which is rotatable and vertically displaceable above the fixed pin ( 6 ). The cross pin ( 7 ) in the bolt engages through the triangular window slot ( 9 ) of the pendulum sleeve, while the spring tongue ( 8 ) attached to the bottom of the pendulum sleeve engages in the saw-blade-shaped lower edge of the switching sleeve ( 10 ). The rotor bar ( 11 ) is rotatable about the fixed disc ( 12 ) with the threaded holes. Bowden cables ( 13 ) are screwed into the tapped holes. The Rotorbal ken is firmly connected to the switching sleeve ( 10 ) and carries the two plungers ( 14 ), the right one is above the bore ( 19 ), while the left one is above the soul end of a Bowden cable. The carrier ring ( 15 ) carries the permanent magnets ( 16 ) and is fixed in height by pins ( 18 ) in the holding bridge ( 20 ) under the electromagnet.

In cross section you can see that each Bowden cable end has a bore ( 19 ) opposite to support the guide when actuating the Bowden cable by lowering the opposite pin despite the eccentric pressure effect on it. This Actuate supply happens by the armature plunger ( 2 ) is lowered during the excitation of the electromagnet ( 1 ). The iron switching disc ( 11 ), which is actually in contact with the permanent magnets ( 16 ), is first torn off by the latter, only then do the plungers penetrate into the holes underneath and prevent rotation of the rotor disc and thus the switching sleeve ( 10 ). Through the bevelled window (see roll-up on the left), the cross pin ( 7 ) causes the pendulum sleeve ( 3 ) to rotate in a clockwise direction while the torsion spring ( 21 ) is tensioned between the same and the switching sleeve. In their sawtooth-like edge recesses, the spring tongue ( 8 ) extending from the pendulum sleeve moves back by one tooth, the steep edge of the flank of the recess preventing the pendulum sleeve from rotating back under the action of the torsion spring. Further work cycles of the magnet can be made in the set switching position if the power supply to the electromagnet is switched on prematurely via the height-adjustable switch ( 22 ) so that the two plungers ( 14 ) do not leave the bores in the drum ( 12 ). If the power is switched on by the switch by turning it off, the plunger ( 14 ) leave the bores and the torsion spring ( 21 ) rotates the pendulum sleeve counterclockwise, taking the switching sleeve and thus the switching disc with the plunger ( 14 ), which come to lie over another pair of holes. With premature activation of the electromagnet via the light barrier, any number of operations on the other Bowden cable can now be achieved. The resilience of the Bowden cable causes the plunger to be raised to the level shown after the power supply to the electromagnet. The residual stroke then takes place under the action of the permanent magnets and thus the distance from the Bowden cable ends. (With appropriate accuracy of the surface design of the drum ( 12 ), the mechanism of the carrier disc with the permanent magnets can be saved). The rotation of the pendulum sleeve despite counter pressure of the anchor tappet ( 2 ) is facilitated by a small ball between the two. The actuation of the switch ( 22 ) still takes place under the action of the electromagnet and brings about a braking solution of the armature movement upwards. If the current is switched on - for example by switching off a thyristor - not effective, the attraction by the permanent magnets causes the remaining stroke, after which rotation of the carrier disk together with the disk ( 11 ) under the action of the torsion spring ( 21 ) is permitted.

Fig. 14 shows above in longitudinal section a magnetic switching device in which differences in the anchor speed are used to switch to other functions. Below is a top view of the drive plate ( 116 ) with the elongated hole ( 137 ) for the passage of the locking pin ( 138 ). To reduce friction, this ends in a ball. The flywheel ( 139 ) is also held in height in the holding fork ( 140 ) with ball bearings. Under the action of the lowering of the armature tappet ( 2 ) by means of a kind of vertically interrupted screw guide ( 141 ) upon pin engagement from the flywheel into this rotation, the latter rotation is accelerated at higher armature speed, so that during the armature return movement due to pressure from Bowden cable ( 13 ) ago the slot of the elongated hole ( 137 ) is reached by the locking pin. The latter can pass through and under the action of the compression spring ( 143 ) there is a lowering of the drive plate ( 136 ) and the actuation of the shift rod ( 114 ), its action on the zigzag profile on the outside of the switching disc ( 11 ) whose sector movement and thus causes the switchover. The work cycle function has already been written to Fig. 9 be.

It is understood that the arrangement by attachment of an anchor with restlessness, for example with appropriate Ver teeth on the outer edge of the flywheel also for cycle-controlled switching can be used. After an ordinary work cycle, the Flywheel back to the starting position have moved back. In the shorter sequence one certain number of work cycles could be the return returns reduced by the same difference what differences add up so far could cause the locking pin to reach the slot and the function switchover is effected.  

Fig. 15 shows an enlarged 1: 2 in longitudinal section of a hose-integrated pulse metering pump. In a plastic block ( 144 ) is cast a silicone rubber hose end ( 145 ), inside which a pin ( 146 ) is loosely mounted, which has a ball ( 147 ) of slightly smaller radius within a spherical chamber in the plastic block ( 148 ) , so that - when diluting the silicone rubber hose in the chamber area still a gap remains ver. The ball chamber is upwards and downwards by annular hose collars ( 149 ). Via the bore ( 150 ), the chamber space is connected to a pressure gas cushion (not shown), while in the vicinity of the hose end there is a liquid outlet channel ( 151 ) to the cannula. A cross plate ( 152 ) with openings for the liquid passage from above within the hose is used for attachment with the driving stroke magnet. The liquid enters under pressure from above and can enter the chamber gap with the ball ( 147 ) lowered, but cannot flow downwards due to the hose duct being laid down. The surrounding pressure gas in the chamber gap space was displaced the liquid of higher pressure. If the pin is moved upwards, the liquid flow to the chamber is shut off at the top, but the liquid outlet below freely against. This he follows under the influence of the pressure gas cushion on the hose wall in the chamber area.

Variants such as the generation of thrust movements by means of a motor in connection with a connecting rod rod or the choice of circular shape for that too lower end of the puncture pen for easier suction gloc sealing or the overlap of parts neighboring housing subspaces should be included, as well as measuring the opening times of the gas outlet step valves and their addition for calculation the time of pressure gas exhaustion. The station wagon nation of this device form with a diaphanic, Puncture-free measuring device is advantageous (WO 86/01 728).

Claims (45)

1. Device for the automatic measurement of metabolic states from blood components with the help of the action of a suction cup on the skin with or without the injection of liquids under the skin of humans or animals, characterized in that the suction cup edge is arranged in parallel with the longest device dimension to prevent premature Prevent prying off the edge of the suction cup and enable use even under the body cover. 2. Device according to claim 1, characterized, that the functional elements within the device Are assigned to subspaces within which one fixed relationship is secured while between the subspaces, within which there are also overlaps of functional parts, a certain Slidability exists, which it at least some elasticity of the housing allowed, a better system of the suction cup environment to ver to achieve curved body surfaces. 3. Device according to claim 1, characterized, that the suction cup in its height shift in Direction to the interior of the housing, determinative according to the pressure on the skin, the change of the puncture agent by shifting it sideways Exercise from the opening to the suction cup away. 4. Device according to claim 1 and 3, characterized,  that the suction bell when raised by means of a Pen, which on a backdrop guide on the edge of a transport wheel affects the sideways movement the puncture means causes. 5. Device according to claim 1, characterized, that when lifting the suction bell as intended under pressure against the skin at least one Spring is tensioned, which is necessary for the execution of further Device functions is used. 6. Device according to claim 1 and 5, characterized, that the tension of at least one spring the lifting by the suction cup of change the distance between the puncture agent and the skin top serves. 7. Device according to claim 1, characterized, that by lifting the bell this Puncture agent until the opening is sealed the suction cup is approached by the puncture agent becomes. 8. Device according to claim 1, characterized, that the dock for storing the punk tion means is connected to the suction cup and is raised when they are raised. 9. Device according to claim 1, characterized, that the puncture means by means of at least one Holding thread connected to a chain are.   10. Device according to claim 1 and 9, characterized, that at least one tether by at least one Drilling through the body of the puncture agent is carried out. 11. The device according to claim 1, characterized, that the cross section of a puncture agent in little deviates at least one section from the circular shape, to align the measuring zone with the light source. 12. Device according to claim 1, characterized, that the entire shaft of the puncture agent is in front use in a hole in the body of the Withdrawal of puncture means is little at times temporary closure of the outlet opening of the shaft to the top of the skin through a kind Membrane. 13. Device according to claim 1, characterized, that behind a sanding zone is a wiping zone and then an acceptor zone, the latter for receiving Blood components, lie, the measuring zone with the indicator substance in the body of the puncture mit into the skin before use diving shaft sections is stored. 14. Device according to claim 1, characterized, that the body of the puncture means one above Hole for receiving a pin, which is the Transport in the vertical serves.   15. Device according to claim 1, characterized, that the upper end of the puncture means of a Is included, which is the carriage in the Vertical serves. 16. Device according to claim 1, characterized, that the movement of the puncture in the sink on the right over a flexible cable. 17. Device according to claim 1, characterized, that the body of the puncture means has a notch has at least which of its transport tax tion along a rail. 18. Device according to claim 1, characterized, that in the body of a puncture a fixed capillary is inserted, which serves to absorb blood components. 19. Device according to claim 1 and 18, characterized, that at least in places parallel to one Capillary there is a ventilation channel which at times with the vacuum room in Is connected. 20. Device according to claim 1, characterized, that a kind of bowl with inside the suction bell central opening for receiving the top of the skin is present, which is the puncture agent is approaching.   21. Device according to claim 1 and 20, characterized, that that kind of shell by magnetic force up to Vacuum accumulation from the puncture agent in Ab is held. 22. Device according to claim 1, characterized, that they with an external light source in Ver bond can be set. 23. Device according to claim 1, characterized, that they have a separate cable connection Measuring device can be connected. 24. Device according to claim 1, characterized, that several springs on separate sliders behind are staggered so that they by moving a bracket one after the other be stretched, with the individual slides through Grid determined and overtaken by the bracket. 25. Device according to claim 1 and 24, characterized, that both spring end points determined by grid , one of which is used to perform the Work function, the other after performing the same is triggered. 26. Device according to claim 1 and 25, characterized, that the triggering of the grid after performing the Work function on the movement of the slide itself is effected.   27. Device according to claim 1, characterized, that to open a valve between one Gas pressure chamber and a gas jet pump Seat valve inside the gas pressure chamber via a Type of bimetal bridge due to thermal expansion of Metal during heating by electrical Rei exercise is opened. 28. Device according to claim 1, characterized, that during the opening of a seat valve a notch in the valve body wall ground valve lifter a connection between Gas storage space and gas jet pump is manufactured. 29. Device according to claim 1, characterized, that with an injection device the Dosvorvor direction from a ball inside a tube which exists via a pin within a round the chamber surrounding the ball in cycles is moved, the liquid under positive pressure is inserted into the hose while the cam emptying by the action of a gas pressure upholstered. 30. Device according to claim 1, characterized, that the timing of the impending shortage warning of compressed gas by measuring the total opening time of the compressed gas valve determined after calculation becomes. 31. Device according to claim 1, characterized,  that especially for injection use Type of electromagnetic switching device available is which by influencing the functioning of an electric power drive by way the power supply in at least two work functions can be used. 32. Device according to claim 1 and 31, characterized, that serves as a power drive, an electric motor, the Rotation in one direction at least one push movement caused by changing direction tion causes the sector rotation of a switching disc the latter being the pushing movements after each their sector turns a different work function communicates. 33. Device according to claim 1 and 32, characterized, that after changing the running direction of the power drive from the work function to the switching function by Her position of the rotary axis coupling with a pinion in the initial phase of this change of direction, at another change of direction via the Mit take the pinion only in this direction an adjustment of the height from this pinion of the working stroke depending on the size of the sector movement of the Ritzels and the feedback of this stroke height adjuster in the starting position at the end of a full Pinion rotation is effected while the pinion is at Continuation of the power drive in the switching direction the pinion again from the rotary axis coupling is resolved, which is also the case when within the switchover for the function selection none Interruption by changing the direction of the rotation was effected.   34. Device according to claim 1 and 31, characterized, that a lifting magnet is used as the electric drive being a difference in height of the anchor movement to differentiate between working and switching stroke is used. 35. Device according to claim 1 and 34, characterized, that by the stroke movement of the magnet armature, in addition to the Transfer of the working stroke by one of the Switch outgoing tappet in one of several Ren holes with the power transmission wires for the work function within a fixed Drum, the sector movement via a backdrop a pendulum sleeve is effected, which pendulum sleeve via a spring stretched over this sector movement with the switching sleeve as part of the switching disc in Connection is established, the spring tension by a Blocking connection between pendulum sleeve and switch disc remains which lock connection that The pendulum sleeve swings back without switching action prevents the tensioned spring from switching disc in the opposite direction around a switch sector stage turns as soon as that from the switching disc outgoing plunger and one in bores without drive function such as an additional moving pin has left standing drum, which leaving due to premature re-excitation of the armature coil is prevented for a long time as still working strokes in the same cher switching position of the switching disc should take place. 36. Device according to claim 1 and 31, characterized, that a lifting magnet is used as the electric drive will and the difference in the speed of Anchor movement to differentiate between working and switching stroke is used.   37. Device according to claim 1 and 31, characterized, that a lifting magnet is used as the electric drive being, the temporal distribution of armature coils excitement to differentiate between work and Switching stroke is used. 38. Device according to claim 1 and 31, characterized, that a lifting magnet is used as the electric drive and through this a flywheel in rotation ver is set, the extent of the sector movement the this flywheel to differentiate between Ar beits- and switching stroke is used. 39. Device according to claim 1 and 31, characterized, that under the lifting action of a working lever a disc adjacent spring while rotating the Washer is tensioned, this spring being used for Transfer of the working stroke called shit can only move in the direction of the axis of rotation, when the disc has reached a rotary position, at which is the locking effect of an axially transverse pin is picked up by a slit. 40. Device according to claim 1, characterized, that the hole for the shaft passage through the Body of the puncture means has a seal. 41. Device according to claim 1 and 40, characterized, that this seal is a stretchable membrane, which with both the body and the shaft seals is firmly connected.   42. Device according to claim 1 and 40, characterized, that this seal is a bellows, which as Cap the body of the puncture device to the shaft and body sits sealed. 43. Device according to claim 1, characterized, that at least one permanent magnet is present, the end positions of the stroke stabilize movement. 44. Device according to claim 1, characterized, that in the area of the suction bell an optical front direction exists to the optical eigen protect the skin in the area of the top of the skin deliver and different districts to each other to compare. 45. Device according to claim 1, characterized, that a device in the area of the suction bell for the transmission of measurement data when irradiated with laser light.