DE3688329T2 - Transdermale applikation von nikotin. - Google Patents

Transdermale applikation von nikotin.

Info

Publication number
DE3688329T2
DE3688329T2 DE8686401095T DE3688329T DE3688329T2 DE 3688329 T2 DE3688329 T2 DE 3688329T2 DE 8686401095 T DE8686401095 T DE 8686401095T DE 3688329 T DE3688329 T DE 3688329T DE 3688329 T2 DE3688329 T2 DE 3688329T2
Authority
DE
Germany
Prior art keywords
nicotine
tobacco
variety
transdermal application
delivered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8686401095T
Other languages
English (en)
Other versions
DE3688329D1 (de
Inventor
Frank T Etscorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New Mexico Tech Research Foundation
Original Assignee
New Mexico Tech Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8196308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3688329(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by New Mexico Tech Research Foundation filed Critical New Mexico Tech Research Foundation
Publication of DE3688329D1 publication Critical patent/DE3688329D1/de
Application granted granted Critical
Publication of DE3688329T2 publication Critical patent/DE3688329T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
DE8686401095T 1986-05-23 1986-05-23 Transdermale applikation von nikotin. Revoked DE3688329T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP86401095A EP0246385B1 (de) 1986-05-23 1986-05-23 Transdermale Applikation von Nikotin

Publications (2)

Publication Number Publication Date
DE3688329D1 DE3688329D1 (de) 1993-05-27
DE3688329T2 true DE3688329T2 (de) 1993-09-23

Family

ID=8196308

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686401095T Revoked DE3688329T2 (de) 1986-05-23 1986-05-23 Transdermale applikation von nikotin.

Country Status (6)

Country Link
US (1) US4597961A (de)
EP (2) EP0246385B1 (de)
AT (1) ATE88366T1 (de)
DE (1) DE3688329T2 (de)
HK (1) HK7794A (de)
SG (1) SG132393G (de)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849226A (en) * 1981-06-29 1989-07-18 Alza Corporation Method for increasing oxygen supply by administering vasodilator
US4954344A (en) * 1981-06-29 1990-09-04 Alza Corporation Method for treating nocturnal angina
US4812313A (en) * 1981-06-29 1989-03-14 Alza Corporation Method for lessening the incidence of anginal attacks
US4765985A (en) * 1985-03-05 1988-08-23 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4953572A (en) * 1985-04-25 1990-09-04 Rose Jed E Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4920989A (en) * 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US5016652A (en) * 1985-04-25 1991-05-21 The Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4821745A (en) * 1985-11-14 1989-04-18 Rosen David I Apparatus and method for overcoming the habit of tobacco smoking
US5316759A (en) * 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
US5055478A (en) * 1986-06-19 1991-10-08 Cooper Thomas M Method for stopping smoking
US6126963A (en) * 1986-08-28 2000-10-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US6110488A (en) * 1986-08-28 2000-08-29 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US5820876A (en) 1986-08-28 1998-10-13 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system
US6117448A (en) * 1986-08-28 2000-09-12 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
USRE37934E1 (en) 1986-08-28 2002-12-10 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system
US6139868A (en) * 1986-08-28 2000-10-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
US5344656A (en) * 1986-09-12 1994-09-06 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
PT86138B (pt) * 1986-11-20 1993-09-30 Ciba Geigy Ag Processo para a activacao transdermica ou topica utilizando um sistema terapeutico transdermico activado pelo utente
US4911707A (en) * 1987-02-13 1990-03-27 Ciba-Geigy Corporation Monolithic user-activated transdermal therapeutic system
CH674618A5 (de) 1987-04-02 1990-06-29 Ciba Geigy Ag
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
US4839174A (en) * 1987-10-05 1989-06-13 Pharmetrix Corporation Novel transdermal nicotine patch
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
US4837027A (en) * 1987-11-09 1989-06-06 Alza Corporation Transdermal drug delivery device
US4781924A (en) * 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device
AU630340B2 (en) * 1987-11-19 1992-10-29 Indaus International Pty. Ltd. Nicotine compositions
US4915950A (en) * 1988-02-12 1990-04-10 Cygnus Research Corporation Printed transdermal drug delivery device
GB8804164D0 (en) * 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5004610A (en) * 1988-06-14 1991-04-02 Alza Corporation Subsaturated nicotine transdermal therapeutic system
US5364630A (en) * 1988-06-14 1994-11-15 Alza Corporation Subsaturated nicotine transdermal therapeutic system
DE3844247A1 (de) * 1988-12-29 1990-07-12 Minnesota Mining & Mfg Vorrichtung, insbesondere pflaster zum transdermalen verabreichen eines medikaments
IE62662B1 (en) * 1989-01-06 1995-02-22 Elan Corp Plc Use of nicotine in the treatment of conditions susceptible to said treatment
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
DE3908432A1 (de) * 1989-03-14 1990-09-27 Lohmann Therapie Syst Lts Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung
MX21452A (es) * 1989-07-07 1994-01-31 Ciba Geigy Ag Preparaciones farmaceuticas que se administran en forma topica.
US5139786A (en) * 1989-07-07 1992-08-18 Ciba-Geigy Corporation Topical formulations
US5230896A (en) * 1989-10-12 1993-07-27 Warner-Lambert Company Transdermal nicotine delivery system
US5077104A (en) * 1989-12-21 1991-12-31 Alza Corporation Nicotine packaging materials
US5508038A (en) * 1990-04-16 1996-04-16 Alza Corporation Polyisobutylene adhesives for transdermal devices
US5147654A (en) * 1990-07-23 1992-09-15 Alza Corporation Oral osmotic device for delivering nicotine
US5156847A (en) * 1990-09-20 1992-10-20 Walter H. Lewis Wound-healing composition
US5035252A (en) * 1990-12-14 1991-07-30 Mondre Steven J Nicotine-containing dental floss
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
US5268179A (en) * 1992-02-14 1993-12-07 Ciba-Geigy Corporation Ultrasonically sealed transdermal drug delivery systems
DE4301782C1 (de) * 1993-01-23 1994-08-25 Lohmann Therapie Syst Lts Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit
US5503844A (en) * 1993-05-18 1996-04-02 Mli Acquisition Corp. Ii Foam laminate transdermal patch
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
US5466465A (en) * 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
EP0743842B1 (de) * 1994-03-07 2003-08-13 Theratech, Inc. Medikament enthaltende, adhesive, zusammenbaubare, transdermale abgabevorrichtung
US5427099A (en) * 1994-03-17 1995-06-27 Adams; Timothy L. Marker for magnetic resonance imaging
AU1958295A (en) * 1994-04-13 1995-11-10 Novartis Ag Temporally controlled drug delivery systems
US5474782A (en) * 1994-05-20 1995-12-12 Woundfast Pharmaceuticals, Inc. Wound-healing composition and method
AU2703795A (en) * 1994-06-23 1996-01-19 Procter & Gamble Company, The Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine
US5730721A (en) * 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
US5760049A (en) * 1997-02-21 1998-06-02 Synapse Pharmaceuticals International, Inc. Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
US6166032A (en) * 1997-02-07 2000-12-26 Synapse Pharmaceuticals International, Inc. Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
EP0991404A1 (de) * 1997-06-24 2000-04-12 Schering-Plough Healthcare Products, Inc. Vorrichtung zur verabreichung von dermatologische wirkstoffe
US5932617A (en) * 1998-02-06 1999-08-03 Woundfast Pharmaceuticals Inc. Wound-treating composition and method
ES2255287T3 (es) 1998-07-09 2006-06-16 Cephalon, Inc. Composiciones para el tratamiento de la leucemia linfocitica cronica.
EP1140039B1 (de) * 1998-12-18 2009-11-04 Alza Corporation Durchsichtige transdermale nicotinabgabevorrichtungen
US6242473B1 (en) 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
US6270781B1 (en) 1999-01-08 2001-08-07 Maxim Pharmaceuticals, Inc. Method and compositions for topical treatment of damaged tissue using reactive oxygen metabolite production or release inhibitors
DE19906979B4 (de) 1999-02-19 2004-07-08 Lts Lohmann Therapie-Systeme Ag Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit
US20030102246A1 (en) * 1999-03-20 2003-06-05 Lts Lohmann Therapie-Systeme Ag Method for improving the stability of stored and/or used light-sensitive therapeutic systems or components thereof
US6328988B1 (en) 1999-04-23 2001-12-11 Rutgers, The State University Of New Jersey Hyperbranched polymeric micelles for encapsulation and delivery of hydrophobic molecules
US7361680B2 (en) * 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7151100B1 (en) * 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7129262B2 (en) * 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7198801B2 (en) * 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
US20070225379A1 (en) * 2001-08-03 2007-09-27 Carrara Dario Norberto R Transdermal delivery of systemically active central nervous system drugs
KR100856523B1 (ko) * 2000-08-03 2008-09-04 안타레스 파르마 아이피엘 에이쥐 충분한 치료효과를 보장하는 활성 화합물의 경피 및/또는경점막 투여용 신규 조성물
US20040198706A1 (en) * 2003-03-11 2004-10-07 Carrara Dario Norberto R. Methods and formulations for transdermal or transmucosal application of active agents
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
US6726920B1 (en) 2000-09-22 2004-04-27 Durect Corporation Implantable drug delivery patch
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
DE10121471A1 (de) * 2001-05-02 2002-11-07 Beiersdorf Ag Oberflächendotierte wirkstoffhaltige Pflaster
CA2453216A1 (en) * 2001-07-12 2003-01-23 Rutgers, The State University Of New Jersey Amphiphilic star-like macromolecules for drug delivery
IL160928A0 (en) * 2001-10-19 2004-08-31 Maxim Pharm Inc Use of histamine to treat liver disease
EP1448127A1 (de) * 2001-11-06 2004-08-25 Maxim Pharmaceuticals, Inc. Zusammensetzungen für die behandlung von infektionskrankheiten
DE10235556A1 (de) * 2002-08-03 2004-02-19 Hf Arzneimittelforschung Gmbh Medikament und Verfahren zur Verringerung des Alkohol- und/oder Tabakkonsums
CA2494155C (en) * 2002-08-22 2011-05-03 Nutrition 21, Inc. Arginine silicate inositol complex and use thereof
WO2004026116A2 (en) * 2002-09-19 2004-04-01 The Regents Of The University Of California Use of etodoclac to treat hyperplasia
CN1703200B (zh) 2002-09-20 2012-02-29 奥尔制药公司 隔离亚单元和相关组合物及方法
EP1648363B1 (de) * 2003-07-03 2019-03-06 Corium International, Inc. Wundverband, vorrichtung zur inhaltsstoffzuführung und iv-hold-down sowie verfahren im zusammenhang damit
NZ546106A (en) * 2003-10-10 2008-10-31 Antares Pharma Ipl Ag Transdermal pharmaceutical formulation for minimizing skin residues
US7387788B1 (en) 2003-10-10 2008-06-17 Antares Pharma Ipl Ag Pharmaceutical compositions of nicotine and methods of use thereof
US20050171192A1 (en) * 2003-12-11 2005-08-04 Gehlsen Kurt R. Use of histamine to treat bone disease
US7611481B2 (en) * 2004-03-24 2009-11-03 Corium International, Inc. Transdermal delivery device
US7425340B2 (en) * 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2006009975A2 (en) * 2004-06-22 2006-01-26 Maxim Pharmaceuticals, Inc. Histamine to treat disorders affecting muscle function
US10016385B2 (en) 2004-12-17 2018-07-10 Alan B. Cash Method for extending lifespan delaying the onset of age-related disease
US7309809B2 (en) * 2005-02-26 2007-12-18 Xennovate Medical Llc Adhesive attachment and removal device
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
KR100699582B1 (ko) 2005-07-11 2007-03-23 삼성전기주식회사 출력 버퍼회로
US8383149B2 (en) * 2005-09-23 2013-02-26 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
US9056061B2 (en) * 2005-09-23 2015-06-16 Alza Corporation Transdermal nicotine salt delivery system
ES2499067T3 (es) * 2005-10-13 2014-09-26 Nitto Denko Corporation Preparación transdérmica de nicotina y método de producción de la misma
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
DK2719378T3 (en) 2006-06-19 2016-10-17 Alpharma Pharmaceuticals Llc pharmaceutical compositions
US7915247B1 (en) 2006-08-21 2011-03-29 Mutual Pharmaceutical Company, Inc. Methods of use of fenofibric acid
WO2008091602A2 (en) 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
DE102007006244B4 (de) 2007-02-08 2012-03-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System zur Verabreichung wasserlöslicher Wirkstoffe
WO2008103818A1 (en) * 2007-02-21 2008-08-28 University Of Louisville Research Foundation Therapeutic cotinine compositions
ES2817249T3 (es) 2007-04-16 2021-04-06 Corium Inc Matrices de microagujas obtenidas mediante disolución y colada que contienen un principio activo
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US8991402B2 (en) 2007-12-18 2015-03-31 Pax Labs, Inc. Aerosol devices and methods for inhaling a substance and uses thereof
JP6306349B2 (ja) 2010-04-14 2018-04-04 アルトリア クライアント サービシーズ リミテッド ライアビリティ カンパニー 予成形無煙タバコ製品
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
CA2798145C (en) 2010-05-04 2022-10-18 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
FR2987561B1 (fr) * 2012-03-02 2014-04-11 Pf Medicament Dispositif transdermique comprenant des micro-particules poreuses
WO2014100750A1 (en) 2012-12-21 2014-06-26 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968887B1 (de) 2013-03-12 2022-05-04 Corium, Inc. Mikroprojektionsapplikatoren
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10799548B2 (en) 2013-03-15 2020-10-13 Altria Client Services Llc Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
WO2014151654A1 (en) 2013-03-15 2014-09-25 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
EP4194028A1 (de) 2013-03-15 2023-06-14 Corium Pharma Solutions, Inc. Mehrfachaufprall-mikroprojektionsapplikatoren
ES2856448T3 (es) 2013-05-06 2021-09-27 Juul Labs Inc Formulaciones de sal de nicotina para cigarrillos electrónicos y método de suministro de nicotina
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
KR102328024B1 (ko) 2013-12-05 2021-11-17 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 액제 및 그 방법
CN106170313B (zh) 2014-04-28 2020-11-10 菲利普莫里斯生产公司 带香味尼古丁粉末吸入器
RU2696570C2 (ru) 2014-04-28 2019-08-06 Филип Моррис Продактс С.А. Ингалятор никотинового порошка
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
WO2016069875A1 (en) 2014-10-30 2016-05-06 Arena Pharmaceuticals, Inc. Compositions and methods for ceasing tobacco smoking
GB2535427A (en) 2014-11-07 2016-08-24 Nicoventures Holdings Ltd Solution
GB2532062A (en) 2014-11-07 2016-05-11 Nicoventures Holdings Ltd Container
US11191735B2 (en) 2015-03-13 2021-12-07 Nutrition 21, Llc Arginine silicate for periodontal disease
WO2016176177A1 (en) 2015-04-27 2016-11-03 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US20170135969A1 (en) 2015-11-12 2017-05-18 Jds Therapeutics, Llc Topical arginine-silicate-inositol for wound healing
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
CA3048820A1 (en) * 2015-12-30 2017-07-06 Next Generation Labs, LLC Nicotine replacement therapy products comprising synthetic nicotine
EA038219B1 (ru) 2016-08-19 2021-07-26 Арена Фармасьютикалз, Инк. Агонисты рецептора 5-ht2c и композиции, а также способ их применения
MX2019002468A (es) 2016-09-01 2019-09-18 Jds Therapeutics Llc Composiciones de biotinato de magnesio y metodos de uso.
AU2017330348B2 (en) 2016-09-22 2023-09-07 Alan B. Cash Method to alleviate the symptoms of PMS
AU2017373857A1 (en) * 2016-12-05 2019-06-13 Morningside Venture Investments Limited Transdermal drug delivery devices and methods
WO2019232077A1 (en) 2018-05-29 2019-12-05 Chrono Therapeutics Inc. Drug delivery methods and systems
WO2019239356A1 (en) 2018-06-15 2019-12-19 R. J. Reynolds Tobacco Company Purification of nicotine
GB2594170A (en) 2018-11-02 2021-10-20 Nutrition 21 Llc Compositions containing inositol-stabilized arginine silicate complexes and inositol for improving cognitive function in video gamers
US10661065B1 (en) * 2019-02-07 2020-05-26 Neil Brereton Jackson Systems, devices, and/or methods for managing transdermal patches
AU2020407071A1 (en) 2019-12-16 2022-07-07 Nutrition 21, Llc Methods of production of arginine-silicate complexes
AU2022207455A1 (en) 2021-01-14 2023-07-27 Alan B. Cash Treatment of pathological fatigue with oxaloacetate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1775998A (en) * 1929-09-19 1930-09-16 Greenberg Joseph Medicated handkerchief
DE1071897B (de) * 1957-12-19 1959-12-24
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3731683A (en) * 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US3742951A (en) * 1971-08-09 1973-07-03 Alza Corp Bandage for controlled release of vasodilators
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
CA1163195A (en) * 1980-06-26 1984-03-06 Alec D. Keith Polymeric diffusion matrix containing a vasodilator
DE3438284A1 (de) * 1984-10-16 1985-03-07 Hans-Harald von 2400 Lübeck Tilly Nikotinhaltiges depotpflaster

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DE3688329D1 (de) 1993-05-27
EP0246385B1 (de) 1993-04-21
ATE88366T1 (de) 1993-05-15
EP0498468B1 (de) 1996-09-25
EP0246385A1 (de) 1987-11-25
HK7794A (en) 1994-02-04
EP0498468A1 (de) 1992-08-12
SG132393G (en) 1994-03-31
US4597961A (en) 1986-07-01

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