DE3677364D1 - Markierte makromolekuele; verfahren zu ihrer herstellung und ihre verwendung in immunologischen oder immunocytochemischen testen. - Google Patents
Markierte makromolekuele; verfahren zu ihrer herstellung und ihre verwendung in immunologischen oder immunocytochemischen testen.Info
- Publication number
- DE3677364D1 DE3677364D1 DE8686904953T DE3677364T DE3677364D1 DE 3677364 D1 DE3677364 D1 DE 3677364D1 DE 8686904953 T DE8686904953 T DE 8686904953T DE 3677364 T DE3677364 T DE 3677364T DE 3677364 D1 DE3677364 D1 DE 3677364D1
- Authority
- DE
- Germany
- Prior art keywords
- macromolecules
- immunological
- marked
- production
- immunocytochemical tests
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8502187 | 1985-08-05 | ||
PCT/NL1986/000022 WO1987000926A1 (en) | 1985-08-05 | 1986-08-04 | Labelled macromolecules; a process for their preparation and their use for immunological or immunocytochemical assays |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3677364D1 true DE3677364D1 (de) | 1991-03-07 |
Family
ID=19846391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686904953T Expired - Lifetime DE3677364D1 (de) | 1985-08-05 | 1986-08-04 | Markierte makromolekuele; verfahren zu ihrer herstellung und ihre verwendung in immunologischen oder immunocytochemischen testen. |
Country Status (5)
Country | Link |
---|---|
US (1) | US5043265A (de) |
EP (1) | EP0232357B1 (de) |
JP (1) | JPS63500400A (de) |
DE (1) | DE3677364D1 (de) |
WO (1) | WO1987000926A1 (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US6379895B1 (en) | 1989-06-07 | 2002-04-30 | Affymetrix, Inc. | Photolithographic and other means for manufacturing arrays |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US6406844B1 (en) | 1989-06-07 | 2002-06-18 | Affymetrix, Inc. | Very large scale immobilized polymer synthesis |
US6040138A (en) * | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
US6346413B1 (en) | 1989-06-07 | 2002-02-12 | Affymetrix, Inc. | Polymer arrays |
US6551784B2 (en) | 1989-06-07 | 2003-04-22 | Affymetrix Inc | Method of comparing nucleic acid sequences |
US6309822B1 (en) | 1989-06-07 | 2001-10-30 | Affymetrix, Inc. | Method for comparing copy number of nucleic acid sequences |
US6506558B1 (en) | 1990-03-07 | 2003-01-14 | Affymetrix Inc. | Very large scale immobilized polymer synthesis |
EP0834576B1 (de) | 1990-12-06 | 2002-01-16 | Affymetrix, Inc. (a Delaware Corporation) | Detektion von Nukleinsäuresequenzen |
CA2069464A1 (en) * | 1991-05-28 | 1992-11-29 | Daniel K. Kohn | Phosphorescent identification device |
US6864101B1 (en) | 1991-11-22 | 2005-03-08 | Affymetrix, Inc. | Combinatorial strategies for polymer synthesis |
DE69233331T3 (de) * | 1991-11-22 | 2007-08-30 | Affymetrix, Inc., Santa Clara | Kombinatorische Strategien zur Polymersynthese |
US6468740B1 (en) | 1992-11-05 | 2002-10-22 | Affymetrix, Inc. | Cyclic and substituted immobilized molecular synthesis |
US6943034B1 (en) | 1991-11-22 | 2005-09-13 | Affymetrix, Inc. | Combinatorial strategies for polymer synthesis |
DE4210970C2 (de) * | 1992-04-02 | 1996-10-17 | Markus Dipl Chem Sauer | Verfahren zur simultanen optischen qualitativen und quantitativen Erfassung von verschiedenen mit Fluorochromen oder Fluorogenen markierten Molekülen eines Gemisches mittels Laserspektroskopie |
EP0606422B1 (de) * | 1992-07-02 | 1997-09-03 | SOINI, Erkki | Biospezifisches multiparameter-analyseverfahren |
FR2693740B1 (fr) * | 1992-07-17 | 1994-10-14 | Univ Joseph Fourier | Procédé de détection tissulaire ou cellulaire mettant en Óoeuvre des réactifs chimiluminescents. |
US6399397B1 (en) * | 1992-09-14 | 2002-06-04 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US6159686A (en) | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
US5674698A (en) * | 1992-09-14 | 1997-10-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US5736410A (en) * | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US5698397A (en) * | 1995-06-07 | 1997-12-16 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
ATE266195T1 (de) * | 1992-09-14 | 2004-05-15 | Stanford Res Inst Int | Up-converting reporter molekül für biologische und andere testverfahren unter verwendung von laseranregungstechniken |
JP3410777B2 (ja) * | 1993-09-13 | 2003-05-26 | 株式会社東芝 | 超微粒子無機蛍光体標識特異的結合物質およびこれを用いた検出方法 |
US7323298B1 (en) | 1994-06-17 | 2008-01-29 | The Board Of Trustees Of The Leland Stanford Junior University | Microarray for determining the relative abundances of polynuceotide sequences |
US7378236B1 (en) | 1994-06-17 | 2008-05-27 | The Board Of Trustees Of The Leland Stanford Junior University | Method for analyzing gene expression patterns |
US6132642A (en) * | 1994-07-01 | 2000-10-17 | Sarnoff Corporation | Method of preparing small particle size phosphors |
US8236493B2 (en) | 1994-10-21 | 2012-08-07 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
KR970051664A (ko) * | 1995-12-29 | 1997-07-29 | 윤종용 | 칼라 음극선관용 형광체 및 그 제조방법 |
EP0880598A4 (de) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | Verfahren zur analyse von nukleinsäure |
GB9811480D0 (en) * | 1998-05-29 | 1998-07-29 | Photonic Research Systems Limi | Evanescent-wave excitation of upconverting labels |
US6545264B1 (en) | 1998-10-30 | 2003-04-08 | Affymetrix, Inc. | Systems and methods for high performance scanning |
US6376149B2 (en) * | 1999-05-26 | 2002-04-23 | Yale University | Methods and compositions for imaging acids in chemically amplified photoresists using pH-dependent fluorophores |
AU5358201A (en) | 2000-04-17 | 2001-10-30 | Univ Yale | Method for measuring diffusion of photogenerated catalyst in chemically amplified resists |
AU2001276867A1 (en) * | 2000-07-11 | 2002-01-21 | Sri International | Encoding methods using up-converting phosphors for high-throughput screening of catalysts |
DE10153829A1 (de) | 2001-11-05 | 2003-05-28 | Bayer Ag | Assay basierend auf dotierten Nanoteilchen |
EP1461307A2 (de) * | 2002-01-07 | 2004-09-29 | Abbott GmbH & Co. KG | Kristallisation von aminosäuren unter schütteln mittels ultraschall |
DE10214019A1 (de) * | 2002-03-30 | 2003-10-16 | Detlef Mueller-Schulte | Lumineszierende, sphärische, nicht autofluoreszierende Silicagel-Partikel mit veränderbaren Emissionsintensitäten und -frequenzen |
US8796030B2 (en) * | 2003-07-12 | 2014-08-05 | Parallel Synthesis Technologies, Inc. | Methods for optically encoding an object with upconverting materials and compositions used therein |
US7056473B2 (en) * | 2004-04-29 | 2006-06-06 | Response Biomedical Corp. | Method and apparatus of quantitative assays |
US7919325B2 (en) * | 2004-05-24 | 2011-04-05 | Authentix, Inc. | Method and apparatus for monitoring liquid for the presence of an additive |
EP1812884A4 (de) | 2004-10-22 | 2009-09-02 | Parallel Synthesis Technologie | Seltenerd-downconvertion-leuchtstoffverbindungen zur optischen codierung von objekten und verfahren und vorrichtungen in bezug darauf |
WO2006093966A2 (en) * | 2005-02-28 | 2006-09-08 | The Trustees Of Princeton University | Sem cathodoluminescent imaging using up-converting nanophosphors |
WO2007051035A1 (en) * | 2005-10-28 | 2007-05-03 | Parallel Synthesis Technologies, Inc. | Methods for fabricating optically encoded particles and methods for optically encoding objects with such particles |
US7858396B2 (en) * | 2005-10-31 | 2010-12-28 | Orasure Technologies, Inc. | Lateral flow assay device with multiple equidistant capture zones |
US8153442B2 (en) * | 2009-10-21 | 2012-04-10 | Siemens Healthcare Diagnostics Inc. | Stabilization of signal generation in particles used in assays |
US10054593B2 (en) | 2015-06-05 | 2018-08-21 | Intelleigent Material Solutions, Inc. | Multiplexed spectral lifetime detection of phosphors |
AU2012325697B2 (en) | 2011-10-21 | 2015-11-26 | Decimadx, Llc | Point-of care immunoassay for quantitative small analyte detection |
CN102866252B (zh) * | 2012-08-09 | 2015-01-21 | 河南省农业科学院 | 磷光二氧化硅纳米颗粒标记的定量检测西马特罗的免疫层析试纸条及制备方法 |
WO2014031902A2 (en) | 2012-08-23 | 2014-02-27 | The Regents Of The University Of California | Spectrally encoded microbeads and methods and devices for making and using same |
CN105705938B (zh) * | 2013-08-19 | 2020-11-06 | 休斯敦大学系统 | 磷光报告物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2478387A (en) * | 1944-06-10 | 1949-08-09 | Eastman Kodak Co | Phosphorescent materials |
SE388969B (sv) * | 1972-11-25 | 1976-10-18 | Hoechst Ag | Forfarande for framstellning av en fluorescerande skerm for ett katodstraleror |
US3886394A (en) * | 1973-09-04 | 1975-05-27 | Rca Corp | Image display employing filter coated phosphor particles |
US4000252A (en) * | 1974-01-04 | 1976-12-28 | Kenneth Kosak | Immunoscintillation cell |
CA1111762A (en) * | 1977-12-28 | 1981-11-03 | David S. Frank | Fluorescent rare earth chelate in polymeric latex particles |
GB2095258B (en) * | 1981-03-19 | 1984-09-05 | Janssen Pharmaceutica Nv | A bright field light microscopic method of localizing tissue antigens |
US4452861A (en) * | 1982-05-20 | 1984-06-05 | Rca Corporation | Solid particles encapsulated with cyanoacrylate polymer |
-
1986
- 1986-08-04 DE DE8686904953T patent/DE3677364D1/de not_active Expired - Lifetime
- 1986-08-04 EP EP86904953A patent/EP0232357B1/de not_active Expired - Lifetime
- 1986-08-04 WO PCT/NL1986/000022 patent/WO1987000926A1/en active IP Right Grant
- 1986-08-04 JP JP61504239A patent/JPS63500400A/ja not_active Expired - Lifetime
- 1986-08-04 US US07/045,060 patent/US5043265A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1987000926A1 (en) | 1987-02-12 |
EP0232357B1 (de) | 1991-01-30 |
US5043265A (en) | 1991-08-27 |
JPS63500400A (ja) | 1988-02-12 |
EP0232357A1 (de) | 1987-08-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3677364D1 (de) | Markierte makromolekuele; verfahren zu ihrer herstellung und ihre verwendung in immunologischen oder immunocytochemischen testen. | |
PT76193A (de) | Fibrinogenzubereitung verfahren zu ihrer herstellung und ihre verwendung | |
DE3578019D1 (de) | Einrichtung mit veraenderlicher spalte und verfahren zu ihrer herstellung. | |
ATE166049T1 (de) | Phthalimidoperoxihexansäure, verfahren zu deren herstellung und deren verwendung | |
DE3577098D1 (de) | Para-phenylensulfid-blockcopolymere, verfahren zu ihrer herstellung und ihre verwendung. | |
DE3682874D1 (de) | Pyranoindolizinderivate und verfahren zu ihrer herstellung. | |
DE3788058D1 (de) | Zelltoxischer antikörperkomplex und verfahren zu seiner herstellung. | |
DE3688093D1 (de) | Durchsichtiger gegenstand und verfahren zu seiner herstellung. | |
DE3582576D1 (de) | Dithioketo-pyrrolo-pyrrole, verfahren zu deren herstellung und verwendung. | |
DE3878326T2 (de) | Kunstlunge der membranart und verfahren zu ihrer verwendung. | |
DE3670483D1 (de) | 3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung. | |
DE3874275D1 (de) | Kollektoren und verfahren zu ihrer herstellung und ihrer verwendung. | |
DE3782224D1 (de) | Waermefixierwalze zur verwendung in einem kopiergeraet und verfahren zu ihrer herstellung. | |
DE3684654D1 (de) | Elektrochemisches element und verfahren zu seiner herstellung. | |
DE3770853D1 (de) | Zellenseparator und verfahren zu dessen herstellung. | |
DE3583912D1 (de) | Feuchtigkeitsfuehler und verfahren zu dessen herstellung. | |
PT83411A (de) | Arylmethylazole und deren salze verfahren zu ihrer herstellung sie enthaltende mittel und ihre verwendung | |
DE3865172D1 (de) | Dehnungsmessstreifen mit gesteuerter kriechung und verfahren zu seiner herstellung. | |
DE3679028D1 (de) | Benzylaminderivate, verfahren zu ihrer herstellung und ihre verwendung. | |
DE3684261D1 (de) | Duennschichtkondensatoren und verfahren zu ihrer herstellung. | |
DE3677812D1 (de) | Polyhydroxypolyether, verfahren zu ihrer herstellung und ihre verwendung. | |
DE3669320D1 (de) | Oxalkylierte polyesteramine,verfahren zu deren herstellung und deren verwendung. | |
DE68906322D1 (de) | Octasubstituierte lithium-phthalocyanine, verfahren zu ihre herstellung und ihrer verwendung in epr. | |
DE3673515D1 (de) | Gonatrien-derivate und verfahren zu ihrer herstellung. | |
DE3765181D1 (de) | Isocarbacycline und verfahren zu ihrer herstellung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN |