DE3478760D1 - Optical apparatus and method for measuring the characteristics of materials by their fluorescence - Google Patents

Optical apparatus and method for measuring the characteristics of materials by their fluorescence

Info

Publication number
DE3478760D1
DE3478760D1 DE8484301942T DE3478760T DE3478760D1 DE 3478760 D1 DE3478760 D1 DE 3478760D1 DE 8484301942 T DE8484301942 T DE 8484301942T DE 3478760 T DE3478760 T DE 3478760T DE 3478760 D1 DE3478760 D1 DE 3478760D1
Authority
DE
Germany
Prior art keywords
fluorescence
measuring
materials
optical apparatus
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301942T
Other languages
English (en)
Inventor
William R Macbride
James A Magee
William B Armiger
Dane W Zabriskie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biochem Sensors Inc
Original Assignee
Biochem Sensors Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochem Sensors Inc filed Critical Biochem Sensors Inc
Application granted granted Critical
Publication of DE3478760D1 publication Critical patent/DE3478760D1/de
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6473In-line geometry
    • G01N2021/6476Front end, i.e. backscatter, geometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • G01N21/8507Probe photometers, i.e. with optical measuring part dipped into fluid sample
DE8484301942T 1983-04-11 1984-03-22 Optical apparatus and method for measuring the characteristics of materials by their fluorescence Expired DE3478760D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/483,559 US4577110A (en) 1983-04-11 1983-04-11 Optical apparatus and method for measuring the characteristics of materials by their fluorescence

Publications (1)

Publication Number Publication Date
DE3478760D1 true DE3478760D1 (en) 1989-07-27

Family

ID=23920561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301942T Expired DE3478760D1 (en) 1983-04-11 1984-03-22 Optical apparatus and method for measuring the characteristics of materials by their fluorescence

Country Status (4)

Country Link
US (1) US4577110A (de)
EP (1) EP0122741B1 (de)
JP (1) JPS6022649A (de)
DE (1) DE3478760D1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6288942A (ja) * 1985-10-15 1987-04-23 Matsushita Graphic Commun Syst Inc 液体現像剤濃度制御装置
US4801187A (en) * 1986-04-30 1989-01-31 Baxter Travenol Laboratories, Inc. Liquid light tube end cap assembly
US4803365A (en) * 1987-05-08 1989-02-07 Biochem Technology Optical probe mounting device
DE3725652A1 (de) * 1987-08-03 1989-02-16 Kadia Diamant Werkzeug zur spanabhebenden bearbeitung
US4893935A (en) * 1988-08-19 1990-01-16 Mandel William R Apparatus and method for optical density measurements of biomass processes
DK96989D0 (da) * 1989-02-28 1989-02-28 Faxe Kalkbrud Aktieselskabet Fremgangsmaade til overvaagning af biologiske processer
US5046854A (en) * 1990-02-01 1991-09-10 The Dow Chemical Company Photometric cell and probe having windows fusion sealed to a metallic body
JP2508557B2 (ja) * 1991-01-19 1996-06-19 株式会社ヨコオ 電動伸縮アンテナの駆動装置及びその過負荷防止クラッチ機構
FI910549A (fi) * 1991-02-05 1992-08-06 Biohit Oy Foerfarande och anordning foer bestaemning av vaetskeprovets fluoresens.
DK66992D0 (da) * 1992-05-21 1992-05-21 Faxe Kalkbrud Aktieselskabet Sensor
US5552319A (en) * 1993-07-20 1996-09-03 Biochem Technology, Inc. Apparatus and method for monitoring and controlling biological activity in wastewater and controlling the treatment thereof
US5401412A (en) * 1993-07-20 1995-03-28 Biochem Technology, Inc. Method and apparatus for monitoring biological activity in wastewater and controlling the treatment thereof
JP3516535B2 (ja) * 1995-09-14 2004-04-05 シスメックス株式会社 粒子分析装置
US7157724B2 (en) * 1996-02-08 2007-01-02 Bright Solutions, Inc. Detection lamp
US6590220B1 (en) * 1996-02-08 2003-07-08 Bright Solutions, Inc. Leak detection lamp
US7253557B2 (en) * 1996-02-08 2007-08-07 Bright Solutions, Inc. Light source provided with a housing enclosing voltage regulator means and method of manufacturing thereof
US5959306A (en) * 1996-02-08 1999-09-28 Bright Solutions, Inc. Portable light source and system for use in leak detection
US5708735A (en) * 1996-03-29 1998-01-13 Benson; David K. Fiber optic device for sensing the presence of a gas
US5918190A (en) * 1996-12-31 1999-06-29 Ontario Cattlemen's Association Software controlled meat probe for use in determining meat tenderness
US20030135122A1 (en) * 1997-12-12 2003-07-17 Spectrx, Inc. Multi-modal optical tissue diagnostic system
US6055451A (en) * 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
US6106718A (en) * 1998-07-01 2000-08-22 Biochem Technology, Inc. Enhanced denitrification process by monitoring and controlling carbonaceous nutrient addition
EP1112022A4 (de) * 1998-09-11 2004-08-04 Spectrx Inc Multi-modale optische gewebediagnosevorrichtung
US20040147843A1 (en) * 1999-11-05 2004-07-29 Shabbir Bambot System and method for determining tissue characteristics
US6193850B1 (en) * 1999-09-20 2001-02-27 General Electric Company Method for direct measurement of polycarbonate compositions by fluorescence
WO2001029539A1 (en) 1999-10-20 2001-04-26 Massachusetts Institute Of Technology Systems and methods for analyzing mixtures using fluorescence
US6603545B2 (en) * 2000-05-31 2003-08-05 Kaiser Optical Systems Optical measurement probe with leak minimization features suited to process control applications
US7277168B2 (en) * 2000-08-29 2007-10-02 Smithkline Beecham Corporation Method and system for real-time fluorescent determination of trace elements
US6782184B2 (en) * 2001-12-04 2004-08-24 J.M. Canty, Inc. Modular insertion device for process illumination and viewing
US8507253B2 (en) * 2002-05-13 2013-08-13 Algae Systems, LLC Photobioreactor cell culture systems, methods for preconditioning photosynthetic organisms, and cultures of photosynthetic organisms produced thereby
US7238954B1 (en) * 2003-10-08 2007-07-03 Fay Jr Theodore Denis Optical external cavities having brewster angle wedges
US7477397B2 (en) * 2003-10-08 2009-01-13 Control Development Incorporated Self-calibrating optical reflectance probe system
US7095500B2 (en) * 2004-01-30 2006-08-22 Nalco Company Interchangeable tip-open cell fluorometer
NL1026306C2 (nl) * 2004-06-02 2005-12-05 Perdix Analytical Systems B V Inrichting en werkwijze voor het vastleggen van optische gegevens van een dispersie.
WO2007002323A2 (en) * 2005-06-23 2007-01-04 Epoc, Inc. System and method for monitoring of end organ oxygenation by measurement of in vivo cellular energy status
US8110395B2 (en) 2006-07-10 2012-02-07 Algae Systems, LLC Photobioreactor systems and methods for treating CO2-enriched gas and producing biomass
US8189042B2 (en) * 2006-12-15 2012-05-29 Pollack Laboratories, Inc. Vision analysis system for a process vessel
US7980024B2 (en) 2007-04-27 2011-07-19 Algae Systems, Inc. Photobioreactor systems positioned on bodies of water
US20090229651A1 (en) * 2008-03-14 2009-09-17 Fay Jr Theodore Denis Solar energy production system
US8512975B2 (en) 2008-07-24 2013-08-20 Biomerieux, Inc. Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements
WO2010062350A1 (en) * 2008-10-31 2010-06-03 Biomerieux, Inc. Methods for detection, characterization and/or identification of microorganisms in a sealed container
US20110068279A1 (en) * 2009-08-11 2011-03-24 Fay Jr Theodore Denis Ultra dark field microscope
DE102010047103A1 (de) * 2010-09-29 2012-03-29 Carl Zeiss Jena Gmbh Flansch zum Abschluss eines optischen Geräts gegenüber einem Probenstrom und optisches Gerät zur teilweisen Anordnung in einem Probenstrom
FR2968764B1 (fr) * 2010-12-13 2012-12-14 Onera (Off Nat Aerospatiale) Sonde optique pour mesurer des caracteristiques physiques et chimiques d'un milieu en ecoulement
US20130061455A1 (en) * 2011-09-09 2013-03-14 Brian William Greene Bio-reactor for the production of bio-fuel from algae
EP2801131A4 (de) * 2011-12-14 2016-02-17 Services Petroliers Schlumberger Festkörperlaser
CN104871357B (zh) 2012-09-09 2018-11-20 百奥堪引赛股份有限公司 电化学生物反应器模块和使用所述模块的方法
WO2015055627A2 (de) * 2013-10-14 2015-04-23 Ife Innovative Forschungs- Und Entwicklungs-Gmbh & Co. Kg Messvorrichtung
US10024835B2 (en) * 2015-07-29 2018-07-17 Advanced Sensors Limited Apparatus for measuring a higher concentration of fluorescent materials in a liquid
US11613724B2 (en) * 2015-12-10 2023-03-28 Rosemount Inc. Single-use bioreactor sensor interface
US10088422B2 (en) 2015-12-28 2018-10-02 Schlumberger Technology Corporation Raman spectroscopy for determination of composition of natural gas
GB2551721B (en) * 2016-06-27 2021-06-02 Sondex Wireline Ltd Optical Sensor
CN107868756A (zh) * 2016-09-28 2018-04-03 罗斯蒙特分析公司 一次性生物反应器传感器接口
DE102017119171A1 (de) * 2017-08-22 2019-02-28 Endress+Hauser Conducta Gmbh+Co. Kg Optische Messsonde
CN117255939A (zh) * 2021-02-10 2023-12-19 罗伯特·博世有限公司 用于分析物检测的光学系统
CN117413170A (zh) * 2021-02-10 2024-01-16 水智有限公司 用于分析物检测的光学系统

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2971429A (en) * 1957-02-06 1961-02-14 American Instr Co Inc Spectro-fluorescence measuring instrument
US3068739A (en) * 1958-06-23 1962-12-18 American Optical Corp Flexible optical probe
US3510648A (en) * 1967-04-25 1970-05-05 Honeywell Inc Apparatus employing ultraviolet radiation for measuring the amount of fluorescent material in a continuously flowing fluid stream
US3918812A (en) * 1973-05-07 1975-11-11 Us Energy Diagnoses of disease states by fluorescent measurements utilizing scanning laser beams
US3854050A (en) * 1973-09-11 1974-12-10 Department Of Health Education High precision fluorometer for measuring enzymatic substrates in tissue
GB1452945A (en) * 1973-10-08 1976-10-20 Partech Electronics Ltd Apparatus for monitoring suspended particles in a liquid
US3941477A (en) * 1974-10-17 1976-03-02 Deutsche Forschungs-Und Versuchsanstalt Fur Luft-Und Raumfahrt E.V. Measuring device for the measurement of fluid flow rates
US4031399A (en) * 1975-02-24 1977-06-21 Beckman Instruments, Inc. Fluorometer
US4036946A (en) * 1975-10-20 1977-07-19 Marcos Kleinerman Immunofluorometric method for measuring minute quantities of antigens, antibodies and other substances
US4055768A (en) * 1976-09-07 1977-10-25 Bromberg Nathan S Light measuring apparatus
DE2925855A1 (de) * 1978-06-30 1980-01-17 Chelsea Instr Ltd Unterwasser- oder untertauchbarer fluoreszenzmesser und verfahren zur benutzung eines solchen instruments
US4197458A (en) * 1978-07-31 1980-04-08 Benno Perren Electro-optical apparatus for the detection of the presence of liquid
DE2842343A1 (de) * 1978-09-28 1980-04-10 Siemens Ag Fluoreszenz-messanordnung
US4221485A (en) * 1979-06-04 1980-09-09 Honeywell Inc. Optical smoke detector
US4295199A (en) * 1979-10-22 1981-10-13 Bio-Rad Laboratories, Inc. Automatic fluorometer and data processor for performing fluorescent immunoassays
DE3020168A1 (de) * 1980-05-28 1981-12-03 Eur-Control Regeltechnik GmbH, 4630 Bochum Vorrichtung zum messen der konzentration von in fluessigkeiten enthaltenem oel
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
DD159566A1 (de) * 1981-06-10 1983-03-16 Hartmut Lucht Spektralfluorometer
JPS608738B2 (ja) * 1982-05-12 1985-03-05 株式会社日立製作所 細胞の螢光偏光度測定装置
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube

Also Published As

Publication number Publication date
EP0122741B1 (de) 1989-06-21
US4577110A (en) 1986-03-18
EP0122741A2 (de) 1984-10-24
JPH0115811B2 (de) 1989-03-20
EP0122741A3 (en) 1985-06-12
JPS6022649A (ja) 1985-02-05

Similar Documents

Publication Publication Date Title
DE3478760D1 (en) Optical apparatus and method for measuring the characteristics of materials by their fluorescence
JPS56153206A (en) Optical clearance measuring apparatus and method
GB2135050B (en) Optical electric-field measuring apparatus
PT80393A (en) Apparatus for the cryofixation of specimens
GB2125967B (en) Method for measuring physical properties of materials
IL66382A0 (en) Method and apparatus for optically measuring linear distances
DE3374216D1 (en) Method of and apparatus for measuring the thickness and the refractive index of transparent materials
EP0145343A3 (en) Optical fibre test method and apparatus for performing the method
GB2160311B (en) Optical measurement apparatus
IL62195A (en) Apparatus and method for measuring optical triangulation
GB2046898B (en) Method of measurement of particles
EP0140029A3 (en) Optical distance measuring apparatus
GB2162943B (en) Apparatus for measuring fluorescence decay characteristics of materials
DE3070876D1 (en) Method and apparatus for measuring antibody levels
JPS57153204A (en) Method of and apparatus for photoelectrically measuring moving fiber material
GB8325921D0 (en) Optical method of measuring displacement
PT80394A (en) Apparatus for the cryofixation of specimens
DE3367027D1 (en) Method for the measurement of the difference in the optical properties of two samples
GB8313496D0 (en) Optical measuring apparatus
GB2128735B (en) Method and apparatus for optically measuring clearance change
GB8814415D0 (en) Method of & apparatus for testing materials
NO172086C (no) Apparat for mikro-induktiv undersoekelse av grunnformasjoner
DE3477514D1 (en) Apparatus for measuring optical transmission factor
HUT34084A (en) Apparatus for optical testing
IL90610A0 (en) Method for measuring rapid optical phenomena and apparatus for measuring these phenomena by this method

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8370 Indication of lapse of patent is to be deleted
8339 Ceased/non-payment of the annual fee