DE3382587D1 - Injizierbares langwirkendes mikroteilchen-praeparat zur verabreichung entzuendungshemmender mittel. - Google Patents

Injizierbares langwirkendes mikroteilchen-praeparat zur verabreichung entzuendungshemmender mittel.

Info

Publication number
DE3382587D1
DE3382587D1 DE8383401489T DE3382587T DE3382587D1 DE 3382587 D1 DE3382587 D1 DE 3382587D1 DE 8383401489 T DE8383401489 T DE 8383401489T DE 3382587 T DE3382587 T DE 3382587T DE 3382587 D1 DE3382587 D1 DE 3382587D1
Authority
DE
Germany
Prior art keywords
solvent
administration
inflammatory agent
inflammatory agents
microparticle preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383401489T
Other languages
English (en)
Other versions
DE3382587T2 (de
Inventor
Thomas R Tice
Danny H Lewis
Donald R Cowsar
Lee R Beck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stolle Research and Development Corp
Original Assignee
Stolle Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stolle Research and Development Corp filed Critical Stolle Research and Development Corp
Publication of DE3382587D1 publication Critical patent/DE3382587D1/de
Application granted granted Critical
Publication of DE3382587T2 publication Critical patent/DE3382587T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE8383401489T 1982-07-29 1983-07-20 Injizierbares langwirkendes mikroteilchen-praeparat zur verabreichung entzuendungshemmender mittel. Expired - Lifetime DE3382587T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/402,857 US4530840A (en) 1982-07-29 1982-07-29 Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents

Publications (2)

Publication Number Publication Date
DE3382587D1 true DE3382587D1 (de) 1992-08-13
DE3382587T2 DE3382587T2 (de) 1992-12-24

Family

ID=23593552

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383401489T Expired - Lifetime DE3382587T2 (de) 1982-07-29 1983-07-20 Injizierbares langwirkendes mikroteilchen-praeparat zur verabreichung entzuendungshemmender mittel.

Country Status (7)

Country Link
US (1) US4530840A (de)
EP (1) EP0102265B1 (de)
JP (1) JPS59161316A (de)
AT (1) ATE77946T1 (de)
CA (1) CA1218306A (de)
DE (1) DE3382587T2 (de)
ES (1) ES8501978A1 (de)

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EP0102265A2 (de) 1984-03-07
ATE77946T1 (de) 1992-07-15
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