DE3203410A1 - Closure body and method for its production - Google Patents

Closure body and method for its production

Info

Publication number
DE3203410A1
DE3203410A1 DE19823203410 DE3203410A DE3203410A1 DE 3203410 A1 DE3203410 A1 DE 3203410A1 DE 19823203410 DE19823203410 DE 19823203410 DE 3203410 A DE3203410 A DE 3203410A DE 3203410 A1 DE3203410 A1 DE 3203410A1
Authority
DE
Germany
Prior art keywords
closure body
closure
body according
items
wire
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19823203410
Other languages
German (de)
Inventor
Joachim Dr.-Ing. DDR 9071 Karl-Marx-Stadt Heinke
Thomas Dr.rer.nat. DDR 8023 Dresden Müller
Heinrich Dr. DDR 8101 Pappritz Paul
Paul Karl Heinz Dr. med. DDR 8060 Dresden Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WAELZLAGER NORMTEILE VEB
Original Assignee
WAELZLAGER NORMTEILE VEB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WAELZLAGER NORMTEILE VEB filed Critical WAELZLAGER NORMTEILE VEB
Publication of DE3203410A1 publication Critical patent/DE3203410A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214—Coils or wires
    • A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0006—Rounded shapes, e.g. with rounded corners circular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0069—Three-dimensional shapes cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section

Abstract

The invention relates to a closure body suitable for internal closure of tubular hollow profiles, especially for the intra-arterial and intravenous closure of blood vessels, and to a method for its production. It is the object of the invention to eliminate the disadvantages of known technical solutions and to provide a closure body which can be employed without open and expensive operating techniques. It is the underlying object to provide a closure body for internal use from a material suitable for implantation purposes and a method for its production. The object is achieved in that a helically-wound wire is formed to give a helical spring body by using relatively high degrees of deformation in such a way that the body can be elastically deformed to give a straight helically-wound wire by application of an external force and assumes a nodular shape when the force is partially cancelled.

Description

Titel der Erfindung Verschlußkörper und Verfahren zu seiner Herstellung Anwendungsgebiet der Erfindung Die Erfindung betrifft einen Verschlußkörper, geeignet zum internen Verschluß rohrförmiger Hohlprofile, insbesondere zum intraarteriellen und intravenösen Verschluß von Blutgefäßen sowie ein Verfahren zu seiner Herstellung.Title of the invention Closure body and process for its manufacture Field of application of the invention The invention relates to a closure body, suitable for the internal closure of tubular hollow profiles, especially for intra-arterial ones and intravenous occlusion of blood vessels and a method for its preparation.

Charakteristik der bekannten technischen Lösungen Die bisher verbreiteste Therapie bei der Bekämpfung stark lokalisierter Karzinome bestand in der sofortigen operativen Entfernung des befallenen Gewebes. Die Gefahr der Metastasierung weiterer Gewebsbereiche war und ist dabei erheblich und grenzt die Erfolgsaussichten in großem Maße ein. Mit den Fortschritten in der Tumorbekämpfung festigte sich deshalb in den letzten Jahren in der Welt die Erkenntnis, daß bei bestimmten Indikationen dieser Mangel durch eine Embolisation vermittels eines Verschlusses der versorgenden Blutgefäße zum Zwecke der Hemmung bzw. Verlangsamung des Tumorwachstums weitestgehend beseitigt werden kann. Eine operative Entfernung ist nachfolgend zumindest nicht in jedem Fall erforderlich.Characteristics of the known technical solutions The most widespread so far Therapy to combat highly localized carcinomas was immediate surgical removal of the affected tissue. The risk of metastasis further Tissue areas was and is considerable and limits the chances of success to a large extent Dimensions a. With the advances in tumor control, the the last few years in the world the realization that with certain indications this Deficiency due to embolization by means of an occlusion of the supplying blood vessels largely eliminated for the purpose of inhibiting or slowing down tumor growth can be. Surgical removal is at least not in everyone afterwards Case required.

Eine derartige Verfahrensweise kann beispielsweise bei Nieren, im Unterleibsbereich von Frauen u.dgl. angewendet werden.Such a procedure can, for example, in kidneys, im Abdominal area of women and the like.

Bekannte technische Lösungen zum Verschluß von Blutgefäßen sind Schlauch- bzw. Arterienklemmen, Fadenschlingen usw. Der Nachteil aller dieser Verschlußelemente besteht darin, daß ihre Applikation nur extern möglich ist. Daraus resultiert die Notwendigkeit der sogenannten offenen Operationstechnik mit erheblichem Aufwand an Zeit, Personal, technischen Hilfsmitteln und wesentlich höheren Belastungen des Patienten. Hierbei entsteht die bereits genannte Gefahr der Metastasierung. Solchen Patienten, die sich bereits im inoperablen Zustand auf Grund bereits eingetretener Tumormetastasierung befinden, kann mit den bisherigen Mitteln nicht geholfen werden.Known technical solutions for the closure of blood vessels are hose or arterial clamps, thread loops, etc. The disadvantage of all these closure elements consists in the fact that their application is only possible externally. This results in the Necessity of the so-called open surgical technique with considerable effort in terms of time, personnel, technical aids and significantly higher loads on the Patient. This creates the already mentioned risk of metastasis. Such Patients who are already in an inoperable state due to already occurred There are tumor metastases, cannot be helped with the previous means.

Ziel der Erfindung Das Ziel der Erfindung besteht darin, die Nachteile bekannter technischer Lösungen zu beseitigen und einen Verschlußkörper zu schaffen, der ohne offene und aufwendige Operationstechnik eingesetzt werden kann.Object of the invention The object of the invention is to overcome the disadvantages to eliminate known technical solutions and to create a closure body, which can be used without open and complex surgical technique.

Darlegung des Wesens der Erfindung Der Erfindung liegt die Aufgabe zugrunde einen Verschlußkörper zur internen Anwendung ~as einem für Implantationezwecke geeigneten Material und ein Verfahren zur Herstellung desselben zu schaffen.Statement of the essence of the invention The object of the invention is to be found based on a closure body for internal use as one for implantation purposes to provide a suitable material and method for making the same.

Merkmale der Erfindung Erfindungsgemäß wird die Aufgabe dadurch gelöst, daß eine Drahtwendel unter Anwendung höherer Umformgrade so zu einem Schraubenfederkörper ausgebildet ist, daß er unter Anwendung eines äußeren Zwanges zu einer geraden Drahtwendel elastisch umformbar ist und nach teilweisem Wegfall desselben eine knotenförmige Gestalt annimmt. Dabei kann der Schraubenfederkörper eine zylindrische, kegelförmige oder tonnenförmige Gestalt aufweisen. Nach einem weiteren Merkmal der Erfindung besitzt der Schraubenfederkörper zur Erhöhung des Abdichteffektes an einem oder an beiden Enden eine Kopfverdickung. Diese Kopfverdickung ist als eine weitere Drahtwendel ausgebildet und auf den Enden des Schraubenfederkörpers angeordnet. Zweckmäßigerweise wird die Kopfverdickung mit dem Schraubenfederkörper durch geeignete und bekannte Verfahren formschlüssig verbunden. Der Schraubenfederkörper und auch die Kopfverdickung sind aus einem gewebeverträglichen, für Humanimplantate geeigneten, hochelastischen und aushärtbaren hochlegierten Eisenwerkstoff hergestellt. Dabei besteht erfindungsgemäß das Verfahren zur Herstellung des Verschlußkörpers aus folgenden Verfahrensschritten: a) Wickeln der Drahtwendel zu einer zylindrischen, tonnenförmigen oder kegelförmigen Bauform b) Form- und Lagefixierung des so gewickelten Körpers c) Wärmebehandlung, ausgeführt als Entspannungsglühen bei 3000 - 5500C, 2 h unter Schutzgas d) Form- und lagefixierte Luft- oder Wasserabkühlung e) Formentspannung Ausfiihrungsbeispiel Die Erfindung soll in einem nachstehenden Ausführungsbeispiel näher erläutert werden, ohne sich darauf zu beschränken. Es zeigen: Fig. 1s einen Schraubenfederkörper in gestreckter Form als Drahtwendel Fig. 2s einen Schraubenfederkörper in gestreckter Form als Drahtwendel mit einer Kopfverdickung Fig. 3: einen Verschlußkörper in zylindrischer Bauform Fig. 4s einen Verschlußkörper in zylindrischer Bauform mit Kopfverdickung an einer Seite Fig. 5: einen Verschlußkörper in kegliger Bauform Fig. 6: einen Verschlußkörper in kegliger Bauform mit Kopfverdickung an einer Seite Fig. 7: einen Verschlußkörper in tonnenförmiger Bauform Fig. 8: einen Verschlußkörper in tonnenförmiger Bauform mit Kopfverdickung auf beiden Seiten Fig. 9: einen Verschlußkörper in einer Arterie eingeführt mit einem Katheter Der Verschlußkörper gemäß Fig. 1 besteht in seiner Ausgangsform, gleich welche Endform gemäß Fig. 3 bis 8 entstehen soll, aus einer Drahtwendel 1. Diese Drahtwendel 1 ist aus einem gewebeverträglichen, für Humanimplantate geeigneten austenitischen Stahl mit 0,02 % CI 18,2 % Cr; 10,4 % Ni; 2,5 % Mo hergestellt. Zur Erhöhung der Verschlußwirkung einerseits sind an einem Ende oder an beiden Enden der Drahtwendel eine Kopfverdickung 2 angeordnet, wobei das Ende der Drahtwendel 1 mit dem Ende der Kopfverdickung 2 formschlüssig verbunden ist. Die Drahtwendel 1 wird entsprechend dem jeweiligen Anwendungsfall in eine zylindrische, Fig. 3 und 4, keglige, Fig. 5 und 6 oder tonnenförmige Endform 7 und 8 verformt. Durch die Drahtwendel 1 mit den Abmessungen 0,18 x 0,9 x 70 mm wird ein Draht, beispielsweise 0,2 mm ~ X 12 Cr Ni 17.7 G gezogen und um einen zylindrischen Körper 4 mm ~ gewickelt. Dabei dient der Draht 0,2 mm ~ als Bindedraht, der die Drahtwendel 1 um den zylindrischen Körper fixiert. Durch eine lageorientierte Vergütungswärmebehandlung bei 4RO°C/2 h unter Schutzgas und anschließender Wasserabkühlung wird ein Verschlußkörper nach Lösen des Bindedrahtes nach Fig. 1 oder 2 mit einem Außendurchmesser von 9 mm hergestellt. Die medizintechnische Nutzanwendung erfolgt mit einem üblichen Plastkatheter 1,8 x 2,5. Fig. 9 zeigt einen eingeführten Verschlußkörper 3 in ein Blutgefäß 4. Nach Ausstoßen des Verschlußkörpers 3 aus dem Katheter 5 befinden sich die einzelnen Windungen unter einem Zwang durch das Blutgefäß 4. Die einzelnen Windungen schieben sich ineinander und hemmen somit in hohem Maße den Blutdurchfluß* Aufstellung über die verwendeten Bezugsseichnn 1 = Drahtwendel 2 = Kopfverdickung 3 = Verschlußkörper 4 = Blutgefäß .5 = KatheterFeatures of the invention According to the invention, the object is achieved by that a wire coil using higher degrees of deformation becomes a helical spring body is designed that he under the application of an external constraint to a straight wire helix is elastically deformable and after partial elimination of the same a knot-shaped Takes shape. The coil spring body can be cylindrical, conical or have a barrel shape. According to a further feature of the invention the coil spring body has to increase the sealing effect on one or a thickening of the head at both ends. This head thickening is available as another wire helix formed and arranged on the ends of the coil spring body. Appropriately is the head thickening with the coil spring body by suitable and known Process positively connected. The coil spring body and also the head thickening are made of a tissue-compatible, highly elastic material suitable for human implants and hardenable high-alloy ferrous material. According to the invention, there is thereby the process for producing the closure body from the following process steps: a) Winding the wire coil into a cylindrical, barrel-shaped or conical shape Design b) shape and position fixation of the wound body c) heat treatment, performed as stress relief annealing at 3000 - 5500C, 2 h under protective gas d) molding and positionally fixed air or water cooling e) Mold relaxation exemplary embodiment The invention is to be explained in more detail in an exemplary embodiment below, without being limited to it. They show: FIG. 1s a helical spring body in FIG stretched form as a wire helix Fig. 2s shows a helical spring body in stretched Form as a wire helix with a head thickening Fig. 3: a closure body in a cylindrical shape Design Fig. 4s shows a closure body in a cylindrical design with a thickened head on one side Fig. 5: a closure body in a conical design Fig. 6: a closure body in a conical shape with a thickened head on one side. Fig. 7: a closure body in barrel-shaped design Fig. 8: a closure body in barrel-shaped design with head thickening on both sides. Fig. 9: an occlusive body in an artery introduced with a catheter. The closure body according to FIG. 1 consists in its Starting shape, whatever the final shape according to FIGS. 3 to 8 is to be created from one Wire helix 1. This wire helix 1 is made of a tissue-compatible one for human implants suitable austenitic steel with 0.02% CI 18.2% Cr; 10.4% Ni; 2.5% Mo produced. To increase the locking effect on the one hand are at one end or at both ends the wire helix a head thickening 2 is arranged, the end of the wire helix 1 is positively connected to the end of the head thickening 2. the Wire helix 1 is according to the respective application in a cylindrical, Fig. 3 and 4, conical, Fig. 5 and 6 or barrel-shaped end shape 7 and 8 deformed. Through the Wire helix 1 with the dimensions 0.18 x 0.9 x 70 mm is a wire, for example 0.2 mm ~ X 12 Cr Ni 17.7 G drawn and wound around a cylindrical body 4 mm ~. The wire 0.2 mm ~ serves as a binding wire, which the wire helix 1 around the cylindrical Body fixed. By means of a position-oriented heat treatment at 4RO ° C / 2 h under protective gas and subsequent water cooling, a closure body is after Loosen the binding wire according to Fig. 1 or 2 made with an outer diameter of 9 mm. The medical technical use takes place with a conventional plastic catheter 1.8 x 2.5. Fig. 9 shows an inserted closure body 3 in a blood vessel 4. After Ejecting the closure body 3 from the catheter 5 are the individual Coils under a force through the blood vessel 4. Push the individual coils into each other and thus inhibit the blood flow to a high degree * Lineup About the reference numbers used 1 = wire helix 2 = head thickening 3 = closure body 4 = blood vessel. 5 = catheter

Claims (7)

tentans ruch 1. Verschlußkörper für rohrförmige Hohlprofile, dadurch gekennzeichnet, daß eine Drahtwendel (1) unter Anwendung höherer Umformgrade so zu einem Schraubenfederkörper ausgebildet ist, daß er unter Anwendung eines äußeren Zwanges zu einer geraden Drahtwendel (1) elastisch umformbar ist und nach teilweisem Wegfall desselben eine knotenförmige Gestalt besitzt.tentans ruch 1. Closure body for tubular hollow profiles, thereby characterized in that a wire helix (1) using higher degrees of deformation so is formed into a coil spring body that he is using an outer Constraint to a straight wire helix (1) is elastically deformable and after partial Elimination of the same has a knot-like shape. 2. Verschlußkörper nach Punkt 1, dadurch gekennzeichnet, daß der Schraubenfeder>brper eine zylindrische, kegelförmige oder tonnenförmige Gestalt aufweist. 2. Closure body according to item 1, characterized in that the Helical spring> brper a cylindrical, conical or barrel shape having. 3. Verschlußkörper nach Punkt 1 und 2, dadurch gekennzeichnet, daß der Schraubenfederkörper an einem oder an beiden Enden Kopfverdickungen (2) aufweist. 3. Closure body according to items 1 and 2, characterized in that the coil spring body has head thickenings (2) at one or both ends. 4. Verschlußkörper nach Punkt 1 bis 3, dadurch gekennzeichnet, daß die Kopfverdickung (2) vorzagsweise aus einer Drahtwendel besteht. 4. Closure body according to items 1 to 3, characterized in that the head thickening (2) preferably consists of a wire helix. 5. Verschlußkörper nach Punkt 1 bis 4, dadurch gekennzeichnet, daß die Enden der Kopfverdickung (2) und der Drahtwendel (1) durch geeignete Verfahren forinschlilssig verbunden sind. 5. Closure body according to items 1 to 4, characterized in that the ends of the head thickening (2) and the wire coil (1) by suitable methods are positively connected. 6. Verschlußkörper nach Punkt 1 bis 5, dadurch gekennzeichnet, daß der Schraubenfederkörper und die Kopfverdickung aus einem gewebeverträglichen, fur Humanimplantate geeigneten, hochelastischen und aushärtbaren hochlegierten Eisenwerkstoff bestehen. 6. Closure body according to items 1 to 5, characterized in that the coil spring body and the head thickening from a fabric-compatible, fur Highly elastic and hardenable high-alloy iron material suitable for human implants exist. 7. Verfahren zur Herstellung des Verschlußkörpers nach Punkt 1 bis 6, gekennzeichnet durch folgende Verfahrensschritte: a) Wickeln der Drahtwendel (1) zu einer zylindrischen' tonnenförmigen oder kegelförmigen Bauform b) Form- und Lagefixierung des so gewickelten Körpers c) Wärmebehandlung, ausgeführt als Entspannungsglühen bei 3000 - 550°C, 2 h unter Schutzgas d) Form- und lagefixierte Luft- oder Wasserabkiihlung e) Formentspannung 7. Process for the production of the closure body according to item 1 to 6, characterized by the following process steps: a) winding the wire coil (1) to a cylindrical 'barrel-shaped or conical design b) shape and Fixing of the body wound in this way. C) Heat treatment, carried out as stress relief annealing at 3000 - 550 ° C, 2 h under protective gas d) Form and position fixed air or water cooling e) Mold relaxation
DE19823203410 1981-05-08 1982-02-02 Closure body and method for its production Withdrawn DE3203410A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD81229818A DD158084A1 (en) 1981-05-08 1981-05-08 CLOSURE BODY AND METHOD FOR ITS MANUFACTURE

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EP0165713A1 (en) * 1984-05-23 1985-12-27 William Cook, Europe A/S A collapsible filter basket
FR2645731A1 (en) * 1989-04-14 1990-10-19 Fondation Avenir Rech Med App System for preventing pulmonary embolisms
FR2652737A1 (en) * 1989-10-09 1991-04-12 Fondation Avenir Rech Medical A filter for preventing pulmonary embolisms and a kit for introducing and positioning it
WO1991004716A1 (en) * 1989-10-09 1991-04-18 Fondation De L'avenir Pour La Recherche Medicale Appliquee Anti-pulmonary embolism filter and kit for storing and applying such filter
FR2671006A1 (en) * 1990-12-28 1992-07-03 Nycomed Ingenor Sa Lab FILTERING DEVICE FOR THE PREVENTION OF EMBOLISMS AND / OR THE DISTENSION OF THE WALLS OF BLOOD VESSELS.
FR2672487A1 (en) * 1991-02-12 1992-08-14 Caburol Guy Adaptable self-centring vein filter which can be implanted on the blood path
FR2673830A1 (en) * 1991-03-14 1992-09-18 Ethnor Improved filter for protecting against pulmonary embolisms, and corresponding kit for presentation and positioning
WO1992016163A1 (en) * 1991-03-14 1992-10-01 Ethnor Improved pulmonary embolism prevention filter and associated positioning and fitting kit
FR2679127A1 (en) * 1991-07-16 1993-01-22 Cleef Jean Francois Van INTRAVENOUS OBSTRUCTION OR HOLDING DEVICE.
FR2683714A1 (en) * 1991-11-19 1993-05-21 Ethnor Improved filter for preventing pulmonary embolisms and corresponding presentation and positioning kit
FR2697995A1 (en) * 1992-11-19 1994-05-20 Celsa Lg Removable blood filtration device, with variable rigidity, implantable in the body of a patient and allowing the injection of a treatment product.
EP0484468A4 (en) * 1990-03-13 1994-07-20 Univ California Endovascular electrolytically detachable guidewire tip
FR2707862A1 (en) * 1993-07-21 1995-01-27 Nycomed Lab Sa System for temporarily sealing an orifice of a perforated organ, such as in particular a vessel.
US5531788A (en) * 1989-10-09 1996-07-02 Foundation Pour L'avenir Pour La Recherche Medicale Appliquee Anti-Pulmonary embolism filter
EP0743866A4 (en) * 1992-11-19 1996-07-26 Target Therapeutics Inc Large diameter vasoocclusion coil
EP0743047A2 (en) * 1995-04-20 1996-11-20 Medical University Of South Carolina Anatomically shaped vasoocclusive device and method of making same
EP0747014A1 (en) * 1995-06-06 1996-12-11 Target Therapeutics, Inc. Multiple layered vaso-occlusive coils
EP0747013A1 (en) * 1995-06-06 1996-12-11 Target Therapeutics Three dimensional in-filling vaso-occlusive coils
EP0765636A2 (en) * 1995-09-29 1997-04-02 Target Therapeutics, Inc. Anatomically shaped Vasoocclusive devices
FR2742650A1 (en) * 1995-12-20 1997-06-27 Braun Celsa Sa Flexible filter tube for blood vessel
WO1997027808A1 (en) * 1996-02-02 1997-08-07 Regents Of The University Of California Clot capture coil
WO1997042881A1 (en) * 1996-05-14 1997-11-20 PFM PRODUKTE FüR DIE MEDIZIN AKTIENGESELLSCHAFT Strengthened implant for bodily ducts
US5695518A (en) * 1990-12-28 1997-12-09 Laerum; Frode Filtering device for preventing embolism and/or distension of blood vessel walls
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USRE42625E1 (en) 1990-03-13 2011-08-16 The Regents Of The University Of California Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
US5855578A (en) * 1990-03-13 1999-01-05 The Regents Of The University Of California Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
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