DE3069307D1 - Process for providing enzyme activity to a surface of an article and an article having enzyme activity on a surface thereof - Google Patents

Process for providing enzyme activity to a surface of an article and an article having enzyme activity on a surface thereof

Info

Publication number
DE3069307D1
DE3069307D1 DE8080303727T DE3069307T DE3069307D1 DE 3069307 D1 DE3069307 D1 DE 3069307D1 DE 8080303727 T DE8080303727 T DE 8080303727T DE 3069307 T DE3069307 T DE 3069307T DE 3069307 D1 DE3069307 D1 DE 3069307D1
Authority
DE
Germany
Prior art keywords
article
enzyme activity
providing
providing enzyme
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080303727T
Other languages
English (en)
Inventor
Takagi Kunihiko
Yabushita Yasunori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unitika Ltd
Original Assignee
Unitika Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unitika Ltd filed Critical Unitika Ltd
Application granted granted Critical
Publication of DE3069307D1 publication Critical patent/DE3069307D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0047—Enzymes, e.g. urokinase, streptokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes
DE8080303727T 1979-10-27 1980-10-22 Process for providing enzyme activity to a surface of an article and an article having enzyme activity on a surface thereof Expired DE3069307D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13912179A JPS5664788A (en) 1979-10-27 1979-10-27 Method for imparting enzyme activity to solid surface

Publications (1)

Publication Number Publication Date
DE3069307D1 true DE3069307D1 (en) 1984-10-31

Family

ID=15237982

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080303727T Expired DE3069307D1 (en) 1979-10-27 1980-10-22 Process for providing enzyme activity to a surface of an article and an article having enzyme activity on a surface thereof

Country Status (4)

Country Link
US (1) US4378435A (de)
EP (1) EP0028122B1 (de)
JP (1) JPS5664788A (de)
DE (1) DE3069307D1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3126551C2 (de) * 1981-07-04 1983-12-15 Rolf Dr. 8700 Würzburg Siegel Herstellungsverfahren für Materialien zur Immobilisierung von Proteinen und Kohlenhydratgruppen
US4401765A (en) * 1981-09-01 1983-08-30 E. I. Du Pont De Nemours And Company Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US5258041A (en) * 1982-09-29 1993-11-02 Bio-Metric Systems, Inc. Method of biomolecule attachment to hydrophobic surfaces
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
SE8205908D0 (sv) * 1982-10-18 1982-10-18 Pharmacia Diagnostics Ab Sett att bilda polymerskikt
JPS59225064A (ja) * 1983-06-03 1984-12-18 ユニチカ株式会社 生理活性物質固定化用担体
US4664658A (en) * 1984-11-08 1987-05-12 Mitsubishi Monsanto Chemical Company Medical material and process for its production
DE3608453A1 (de) * 1986-03-14 1987-09-17 Boehringer Mannheim Gmbh Verfahren zur enzymatischen bestimmung von bilirubin im serum
US4794090A (en) * 1986-09-26 1988-12-27 W. R. Grace & Co.-Conn. Immobilization support for biologicals
WO1988002623A1 (en) * 1986-10-17 1988-04-21 Bio-Metric Systems, Inc. Improvement of the biocompatibility of solid surfaces
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
NL8701337A (nl) * 1987-06-09 1989-01-02 Sentron V O F Substraat voorzien van een bloedcompatibel oppervlak, verkregen door koppeling aan het oppervlak van een fysiologisch aktieve stof met remmende invloed op de vorming van bloedstolsels en/of in staat om gevormde bloedstolsels af te breken, alsmede werkwijze ter vervaardiging van het substraat.
US4882148A (en) * 1987-06-18 1989-11-21 Corvita Corporation Crack prevention and improved thrombogenicity of implanted prostheses by sulfonation
US4906465A (en) * 1987-10-19 1990-03-06 Massachusetts Institute Of Technology Antithrombogenic devices containing polysiloxanes
JPH0245040A (ja) * 1988-08-03 1990-02-15 Terumo Corp 減圧採血管
US5126140A (en) * 1988-08-03 1992-06-30 New England Deaconess Hospital Corporation Thrombomodulin-coated bicompatible substance
EP0388480A1 (de) * 1989-03-20 1990-09-26 Siemens Aktiengesellschaft Implantierbare Reizelektrode
JPH0382472A (ja) * 1989-08-28 1991-04-08 Terumo Corp 生体内長期埋植材及びその製造方法
IT1247946B (it) * 1991-05-17 1995-01-05 Instrumentation Lab Srl Stabilizzazione in forma liquida dell'enzima urato ossidasi
US5356433A (en) * 1991-08-13 1994-10-18 Cordis Corporation Biocompatible metal surfaces
JPH05285164A (ja) * 1992-04-03 1993-11-02 Unitika Ltd 抗血栓性眼内レンズ
US5336518A (en) * 1992-12-11 1994-08-09 Cordis Corporation Treatment of metallic surfaces using radiofrequency plasma deposition and chemical attachment of bioactive agents
US5531789A (en) * 1993-12-24 1996-07-02 Sun Medical Technology Research Corporation Sealing system of an artificial internal organ
US5869127A (en) * 1995-02-22 1999-02-09 Boston Scientific Corporation Method of providing a substrate with a bio-active/biocompatible coating
US6558798B2 (en) 1995-02-22 2003-05-06 Scimed Life Systems, Inc. Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity
US5731087A (en) * 1995-06-07 1998-03-24 Union Carbide Chemicals & Plastics Technology Corporation Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US5672638A (en) * 1995-08-22 1997-09-30 Medtronic, Inc. Biocompatability for solid surfaces
US6416546B1 (en) 1997-06-04 2002-07-09 Unitika Ltd. Medical device and production method thereof
JPH10328293A (ja) * 1997-06-04 1998-12-15 Unitika Ltd 医療用具及びその製造方法
US20030118572A1 (en) * 1997-12-29 2003-06-26 Novozymes A/S Modified enzymes
US6214594B1 (en) 1998-05-08 2001-04-10 University Of California Size enhanced fibrinolytic enzymes: limitations of plasma inactivation
US6348042B1 (en) * 1999-02-02 2002-02-19 W. Lee Warren, Jr. Bioactive shunt
JP2001276210A (ja) * 2000-03-28 2001-10-09 Unitika Ltd 抗菌性医療用具及びその製造方法
US6770024B1 (en) 2000-03-28 2004-08-03 Stony Brook Surgical Innovations, Inc. Implantable counterpulsation cardiac assist device
JP2001276211A (ja) * 2000-03-28 2001-10-09 Unitika Ltd 生理活性を有する抗菌性医療用具及びその製造方法
JP4352600B2 (ja) * 2000-09-01 2009-10-28 ソニー株式会社 データ改竄チェック装置および方法、ならびに、記録媒体
US7407668B2 (en) * 2002-01-24 2008-08-05 Boston Scimed, Inc. Medical articles having enzymatic surfaces for localized therapy
EP2796041B1 (de) * 2006-03-31 2016-04-27 Koch Agronomic Services, LLC Verfahren zur herstellung beschichteter harnstoffformaldehydpolymere
JP5642540B2 (ja) 2007-06-01 2014-12-17 アロウ・インターナショナル・インコーポレイテッドＡｒｒｏｗ Ｉｎｔｅｒｎａｔｉｏｎａｌ， Ｉｎｃ． 組み合わされた線維素溶解性および抗菌性のカテーテル、およびその使用
US8545459B2 (en) 2009-02-25 2013-10-01 Teleflex Medical Incorporated Stabilized enzyme compositions
US9333280B2 (en) 2009-02-25 2016-05-10 Teleflex Medical Incorporated Stabilized enzyme compositions
CA2925858A1 (en) 2013-09-30 2015-04-02 Teleflex Medical Incorporated Stabilized enzyme compositions
US10501383B2 (en) 2014-10-31 2019-12-10 Koch Agronomic Services, Llc Nitrification inhibitor compositions and methods of making thereof
US10881781B1 (en) * 2020-04-29 2021-01-05 Orth Consulting, Llc Blood processing apparatus and method for detoxifying bacterial lipopolysaccharide
US11103628B1 (en) * 2020-04-29 2021-08-31 Orth Consulting, Llc Blood processing apparatus and method for detoxifying bacterial lipopolysaccharide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1603393A (de) * 1967-12-27 1971-04-13
US3649457A (en) * 1968-09-27 1972-03-14 Monsanto Co Enzymatic processing with polymer-enzyme product
DE1945748A1 (de) * 1968-09-27 1970-04-02 Monsanto Co Enzymatisch aktives Addukt,Verfahren zu seiner Herstellung und seine Verwendung
GB1274869A (en) * 1969-02-11 1972-05-17 Guinness Son & Co Ltd A Enzymes
US3715278A (en) * 1970-02-11 1973-02-06 Monsanto Co Enzyme-polymer product attached to surface of siliceous materials thereof
DE2008990A1 (de) * 1970-02-26 1971-09-09 Merck Patent Gmbh Vernetzte Polymerisate zur covalenten Bindung von Substanzen mit reaktionsfähi gen Gruppen
US3941756A (en) * 1972-03-20 1976-03-02 Bayer Aktiengesellschaft New water-insoluble preparations of peptide materials, their production and their use
DE2215539C2 (de) * 1972-03-30 1984-08-02 Bayer Ag, 5090 Leverkusen Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate
DE2614192C2 (de) * 1976-04-02 1986-09-18 FMC Corp., Wilmington, Del. Analysenvorrichtung und Analysenverfahren
US4229536A (en) * 1978-12-28 1980-10-21 Uop Inc. Process for preparing immobilized enzymes

Also Published As

Publication number Publication date
JPS6214273B2 (de) 1987-04-01
EP0028122B1 (de) 1984-09-26
EP0028122A3 (en) 1982-03-31
JPS5664788A (en) 1981-06-02
EP0028122A2 (de) 1981-05-06
US4378435A (en) 1983-03-29

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee